Clinical trials: Morbid Obesity, open to volunteers
Obesity, Morbid
Bariatric Surgery and Pharmacokinetics of Enalapril
Changes to gastric pH, gastric emptying time, gastrointestinal transit-time or the pre-systemic metabolizing effect of enzymes secreted in the mucosa may all alter the pharmacokinetics of medicines.
- Trial name
- NCT03460366
- Testing
- Enalapril
- Where
- Norway
- Volunteers
- 12 people
- Sponsor
- Norwegian University of Science and Technology
Obesity, Morbid
Bariatric Surgery and Pharmacokinetics of Fluoxetine
Changes to gastric pH, gastric emptying time, gastrointestinal transit-time or the pre-systemic metabolizing effect of enzymes secreted in the mucosa may all alter the pharmacokinetics of medicines.
- Trial name
- NCT03476525
- Testing
- Fluoxetine
- Where
- Norway
- Volunteers
- 12 people
- Sponsor
- Norwegian University of Science and Technology
Obesity, Morbid
Bariatric Surgery and Pharmacokinetics of Gabapentin
Changes to gastric pH, gastric emptying time, gastrointestinal transit-time or the pre-systemic metabolizing effect of enzymes secreted in the mucosa may all alter the pharmacokinetics of medicines.
- Trial name
- NCT03476538
- Testing
- Gabapentin
- Where
- Norway
- Volunteers
- 12 people
- Sponsor
- Norwegian University of Science and Technology
Obesity, Morbid
Bariatric Surgery and Pharmacokinetics of Hydrochlorothiazide
Changes to gastric pH, gastric emptying time, gastrointestinal transit-time or the pre-systemic metabolizing effect of enzymes secreted in the mucosa may all alter the pharmacokinetics of medicines.
- Trial name
- NCT03476551
- Testing
- Hydrochlorothiazide
- Where
- Norway
- Volunteers
- 12 people
- Sponsor
- Norwegian University of Science and Technology
Obesity, Morbid
Bariatric Surgery and Pharmacokinetics of Ibuprofen
Changes to gastric pH, gastric emptying time, gastrointestinal transit-time or the pre-systemic metabolizing effect of enzymes secreted in the mucosa may all alter the pharmacokinetics of medicines.
- Trial name
- NCT03476577
- Testing
- Ibuprofen
- Where
- Norway
- Volunteers
- 12 people
- Sponsor
- Norwegian University of Science and Technology
Obesity, Morbid
Bariatric Surgery and Pharmacokinetics of Irbesartan
Changes to gastric pH, gastric emptying time, gastrointestinal transit-time or the pre-systemic metabolizing effect of enzymes secreted in the mucosa may all alter the pharmacokinetics of medicines.
- Trial name
- NCT03476603
- Testing
- Irbesartan
- Where
- Norway
- Volunteers
- 12 people
- Sponsor
- Norwegian University of Science and Technology
Obesity, Morbid
Bariatric Surgery and Pharmacokinetics of Lercanidipine
Changes to gastric pH, gastric emptying time, gastrointestinal transit-time or the pre-systemic metabolizing effect of enzymes secreted in the mucosa may all alter the pharmacokinetics of medicines.
- Trial name
- NCT03497156
- Testing
- Lercanidipine
- Where
- Norway
- Volunteers
- 12 people
- Sponsor
- Norwegian University of Science and Technology
Obesity, Obesity, Morbid
Trans-nasal Endoscopy for Bariatric Patients
This study plans to learn if the EvoEndo Endoscopy system can be used to evaluate, provide and follow up care for upper gastrointestinal tract diseases in the bariatric population.
- Conditions
- Obesity, Obesity, Morbid, Obese, GI Disorders
- Trial name
- TNE (NCT06200961)
- Testing
- Transnasal Endoscopy, Esophagogastroduodenoscopy
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Christopher C. Thompson, MD, MSc
Morbid Obesity, Anorectal Diseases
GLP-1 Receptor Agonists and Early Proctologic Effects in Morbid Obesity
Prospective observational cohort study evaluating the early proctologic effects of GLP-1 receptor agonist therapy in morbidly obese patients.
- Conditions
- Morbid Obesity, Anorectal Diseases, Drug-Related Side Effects and Adverse Reactions, Constipation
- Trial name
- GLP-PROCT (NCT07668765)
- Testing
- GLP-1 receptor agonist therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Gazi University
Obesity, Morbid, Bariatric Surgery Candidate
Obesity Cohort : Medical Follow-up of Severe or Morbid Obese Patients Undergoing Bariatric Surgery
The aim of this cohort is to evaluate the follow-up of morbidly obese patients treated by several types of bariatric procedures.
- Trial name
- BAREVAL (NCT02310178)
- Testing
- Bariatric surgery
- Where
- France
- Volunteers
- 750 people
- Sponsor
- University Hospital, Montpellier
Obesity, Morbid
Low Impact Laparoscopy In Bariatric Surgery
The goal of this clinical trial is to learn if low pressure pneumoperitoneum and small incisions (low impact laparoscopy, LIL) works to reduce pain and improve pulmonary function in patients underwent to bariatric surgery.
- Trial name
- LILYBET (NCT07119437)
- Testing
- low pneumoperitoneum laparoscopy with microsurgery, standard laparoscopy
- Where
- Italy
- Volunteers
- 128 people
- Sponsor
- Fondazione Policlinico Universitario Campus Bio-Medico
Obesity, Morbid, Bariatric Surgery
Evaluation of Metabolic Parameters, Intestinal Permeability and Gastrointestinal Symptoms After Bariatric Surgery in Body Weight Management
This study aims to evaluate the changes in metabolic parameters, intestinal permeability, and gastrointestinal symptoms in individuals who have undergone bariatric surgery (Laparoscopic Sleeve Gastrectomy - LSG) for obesity…
- Conditions
- Obesity, Morbid, Bariatric Surgery, Intestinal Permeability, Gastrointestinal Symptoms
- Trial name
- METABAR (NCT07643376)
- Testing
- Clinical and Biochemical Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Toros University
Morbid Obesity
Impact of Bariatric Surgery on Female Sexual Function and Sex Hormones
The goal of this observational study is to learn about how weight loss surgery (also called bariatric surgery) affects sexual function and sex hormone levels in women with severe obesity.
- Trial name
- NCT07446972
- Testing
- Sleeve Gastrectomy, Gastric Bypass
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Abdominal Aortic Aneurysm, Morbid Obesity
Pilot Study on the Effectiveness and Safety of OPTILENE® SILVER MESH ELASTIC in Prevention of Surgical Site Infection (SSI) and Incisional Hernia (IH)
The aim of the study is to describe the effectiveness of Optilene® Silver Mesh Elastic on prevention of surgical site infection (SSI) at 6 months follow-up in patients undergoing urgent laparotomy by collecting clinical data on…
- Trial name
- SSIHLVER (NCT06547138)
- Testing
- Prophylactic mesh
- Where
- 5 sites in Spain
- Volunteers
- 110 people
- Sponsor
- Aesculap AG
Morbid Obesity, Bariatric Surgery Candidate
Determinants of the Long-Term Success of Bariatric Surgery
The management of obesity is based on a multidisciplinary approach and justifies the use of surgery in patients with the most severe forms.
- Trial name
- PRECOS (NCT03517072)
- Where
- 4 sites in France
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Lille
Obesity & Overweight, Morbid Obesity
Investigation of the Effects of Whole Body Vibration Application on Muscle Functional Level, Physical Fitness and Respiratory Parameters After Bariatric Surgery
The aim of this study was to investigate the effects of whole body vibration on muscle functional level, physical fitness and respiratory parameters after bariatric surgery.
- Conditions
- Obesity & Overweight, Morbid Obesity, Morbid Obesity Requiring Bariatric Surgery
- Trial name
- NCT07602959
- Testing
- Resistance Training, Whole Body Vibration, Control Group
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kirsehir Ahi Evran Universitesi
Obesity, Respiratory Insufficiency
Inhaled Nitric Oxide in Severe Obesity
The goal of this clinical trial is to learn about the effects of inhaled nitric oxide on oxygenation and lung perfusion in participants with severe obesity who have acute hypoxemic respiratory failure and are on mechanical…
- Conditions
- Obesity, Respiratory Insufficiency, Hypoxemic Respiratory Failure, Nitric Oxide
- Trial name
- NCT06675435
- Testing
- Nitric oxide
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Morbid Obesity
Metabolic Responses to Bariatric Surgery
Research the genetic and biomechanical markers of human adipose tissue on patients with morbid obesity. Additional tissue/fluid collection is also gathered during the time of surgery.
- Trial name
- NCT02024542
- Testing
- Surgery
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- University of California, Davis
Obesity, Morbid
Laparoscopic Single Anastomosis Sleeve Ileal Bypass Versus Laparoscopic Sleeve Gastrectomy for Morbid Obesity
This study will compare two bariatric surgical interventions in terms of weight loss, gastroesophageal reflux, and effects on obesity-related comorbid conditions in morbidly obese patients.
- Trial name
- NCT05611697
- Testing
- Single anastomosis sleeve ileal bypass, Sleeve gastrectomy
- Where
- 2 sites in Norway
- Volunteers
- 220 people
- Sponsor
- Oslo University Hospital
Morbid Obesity
Stool Analysis After Sleeve Gastrectomy vs Gastric Bypass
The goal of this observational study is to learn whether routine stool tests can detect changes in gut function 6 months after two common types of weight loss surgery: sleeve gastrectomy and gastric bypass (including mini gastric…
- Trial name
- NCT07461610
- Testing
- Laparoscopic Sleeve Gastrectomy, Mini Gastric Bypass, Roux-en-Y Gastric Bypass
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University