Clinical trials: Mood Change
Mood Change, Emotion Regulation
Interoception and Emotion Regulation
The goal of this observational study is to examine the role of interoception in emotion regulation of negative mood in healthy individuals. Participants will fulfill several questionnaires and perform the Heartbeat Counting Task.
- Trial name
- INTEROEMOTION3 (NCT05684614)
- Testing
- Negative mood induction procedure, Spontaneous emotion regulation task, Positive mood induction procedure
- Where
- 3 sites in Spain
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Cognitive Change, Mood
Effect of PeakATP on Mood, Reaction Time and Cognition
Oral ATP disodium (adenosine 5'- triphosphate disodium) is a commercially available product available alone and as a constituent in a number of sports supplements that is purported to maintain ATP levels and improve performance…
- Trial name
- NCT05100589
- Testing
- PeakATP
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Mood, Cognitive Change
Hypo-hydration Mood and Cognition
Recently changes in mood and cognition have been reported following minor reductions in hydration status. The aim is to explore that such changes in part at least reflect placebo response; therefore the consumption of plain or…
- Trial name
- NCT03948230
- Testing
- Salt with / without water
- Where
- 2 sites in United Kingdom
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Swansea University
Alcohol Craving, Mood Changes
A Dose Response Effect of Atomoxetine to the Acute Effects of Alcohol
This two-stage study will examine the effects of a 5 day course of atomoxetine (placebo, 40, 60 or 80 mg/day; Strattera) (a selective NE transporter (NET) inhibitor) on alcohol-elicited craving and sensitivity to alcohol.
- Trial name
- ATX_COMT (NCT01408589)
- Testing
- Atomoxetine, Strattera
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Appetite, Mood
Effects of Dietary Protein Intake From Beef/Pork and Soy/Legumes on Appetite, Mood, and Weight Loss
The primary aims of this study are to assess the effects of habitual dietary protein intakes across the acceptable macronutrient distribution range with lean beef/pork or soy/legumes as the predominate sources of protein on…
- Conditions
- Appetite, Mood, Weight Loss
- Trial name
- NCT01005563
- Testing
- Beef/Pork, Soy/Legumes
- Where
- 2 sites in United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Purdue University
Depression, Anxiety
Tracking Mood and Language Change Across a Phone-based Mindfulness Intervention
The objective of this study is to administer a brief, phone(voice)-based training program in mindfulness (or control task of active listening to narrated articles) to older adults who receive primary care services at NM.
- Trial name
- NCT04861844
- Testing
- mindfulness training, active listening
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Cognitive Change, Effects of Ginseng on Cognitive Function
Investigating the Acute and Chronic Effects of an American Ginseng Root Extract on Cognition and Mood
Ginseng refers to the extract of any slow growing perennial plant with a fleshy root, deriving from the Panax genus of the Araliaceae family.
- Trial name
- NCT03579095
- Testing
- Cereboost
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Reading
Bipolar Disorder, Schizophrenia
Change in Brain Bioenergetics in Bipolar Disorder in Response to Photic Stimulation
This study aims to gather additional information to support the theory that bipolar disorder is due to cellular (mitochondrial) dysfunction.
- Conditions
- Bipolar Disorder, Schizophrenia, Healthy Controls
- Trial name
- NCT00801567
- Testing
- Magnetic resonance spectroscopy (MRS)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mclean Hospital
Mood, Diet Modification
The Effect of Glycaemic Index Variation on Blood Glucose and Mood in Healthy Participants Across the Day
This study provided 24 healthy subjects with two diets that varied in their glycaemic index values. One condition was a low GI diet, whilst the other was a high GI diet.
- Conditions
- Mood, Diet Modification, Glucose, Low Blood, Glucose, High Blood
- Trial name
- NCT03344185
- Testing
- Low Glycaemic Diet, High Glycaemic Diet
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Matthew Grout
Cognitive Change, Affect
Cognitive Effects of Mint Essential Oil
This study investigates the cognitive and mood effects of mint essential oils in a group of healthy, human adults. The investigational product will also be tested in vitro to ensure a number of biological mechanisms.
- Trial name
- NCT03475836
- Testing
- Mentha piperita
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Healthy
Phenytoin as a Neuroprotective Agent Against Corticosteroid-induced Functional Imaging Changes
The purpose of this research is to determine if patients who receive phenytoin (also commonly known as Dilantin) before taking corticosteroids will show less memory impairment and hypomanic symptoms (feelings of agitation…
- Trial name
- NCT00591006
- Testing
- Phenytoin (brand name Dilantin), Hydrocortisone
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Major Depression, Treatment
fMRI Study of Treatment Changes in Major Depression
The overall purposes of this research are to determine if Cognitive Behavioral Therapy (CBT) has the same healing effect on the brain for people with depression as traditional antidepressants do, and in comparison to healthy…
- Trial name
- NCT01027559
- Testing
- Sertraline, Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Nicotine Dependence
IV Nicotine Induced Changes in Hormone Function, Mood States and Behavior
Clinical studies are proposed to analyze the interactions between nicotine, alterations in endocrine hormones, mood and cardiovascular measures.
- Trial name
- NCT01589055
- Testing
- Intravenous Nicotine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mclean Hospital
Menopause
Estrogen and Serotonin on Changing Brain Chemistry
The aim of this study is to examine the effects of estrogen and serotonin on cognition, emotional processing, and brain activation.
- Trial name
- NCT01208324
- Testing
- estrogen patch, Amino acids
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
PMS, Menstrual Cramp
A Randomized Placebo-Controlled Study to Evaluate the Effects of a Gummy and Capsule Supplement on Symptoms of Premenstrual Syndrome
This virtual, randomized, placebo-controlled clinical trial evaluates the effectiveness of a PMS capsule and PMS gummy in alleviating premenstrual syndrome symptoms over 12 weeks.
- Conditions
- PMS, Menstrual Cramp, Mood Change
- Trial name
- NCT06763809
- Testing
- PMS Capsule, PMS Gummy
- Where
- United States
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Semaine Health
Sleep, Healthy Vollunteer
Wearable Sleep EEG and Auditory Stimulation in Healthy Adults
The purpose of this single-site pilot study is to evaluate the feasibility, usability, and technical performance of a wearable sleep-monitoring system that records electroencephalography (EEG) and delivers brief, low-volume…
- Trial name
- NCT07808645
- Testing
- Wearable EEG-Based Sleep Monitoring and Closed-Loop Auditory Stimulation System
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Houston
Sleep Disturbance, Mood Disturbance
Enhancement of Sleep Quality and Mood Following Supplementation With Lemon Balm in an Adult Population (Lemslp)
This study aims to investigate the effect of a 4-week dietary intervention of 300mg encapsulated aqueous lemon balm extract on measures of sleep quality, mood and well-being, alongside relevant biomarkers of circadian rhythms in…
- Trial name
- NCT05422599
- Testing
- Lemon balm
- Where
- United Kingdom
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Reading
Depression, Treatment Resistant Depression
Computational Psychiatric Approach to Depression
The purpose of this research is to investigate how the brain changes in patients undergoing electroconvulsive (ECT) treatment for depression.
- Trial name
- NCT04189939
- Testing
- clinical assessments
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Anxiety Disorder, Depressive Disorder
Feasibility of a Culturally Adapted Emotional-Behavioral Prevention Program for American Indian Children
American Indians (AI) are at greater risk for anxiety and depression early in life. This is concerning given the potential negative effects of these conditions across the lifespan (substance use, suicide).
- Trial name
- NCT05371665
- Testing
- Culturally Adapted Cognitive-Behavioral Prevention and Early Intervention (PEI) Program
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Montana State University
Cerebrovascular Disease
Aerobic Dance Training in Small Vessel Disease
Introduction: Cerebral small vessel disease (SVD) is associated with age-related disabilities including dementia, depression, physical and functional impairment. Chinese are more prone to developing SVD than Caucasians.
- Trial name
- ADTSVD (NCT02730065)
- Testing
- Structured Aerobic Dance Training Group, Stretching plus education
- Where
- 2 sites in Hong Kong
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong