Clinical trials: Mohs Surgery
Carcinoma, Basal Cell
Recurrence Rate and Esthetic Outcome After Excision of Basal Cell Carcinomas Excluded From Trial NCT00515970
Currently, we conduct a prospective, randomized trial comparing the outcome of surgical excision with the outcome of curettage in nodular and superficial BCCs.
- Trial name
- NCT00639652
- Testing
- 3D-histology, Shave excision
- Where
- Germany
- Volunteers
- 800 people
- Sponsor
- University Hospital Tuebingen
Scar
Forehead Scars Following Mohs Micrographic Surgery and Reconstruction for Skin Cancer
This study will test if the use of DysportTM (abobotulinumtoxinA) improves wound healing and scarring after Mohs surgery. Research in the laboratory as well as previous studies in humans have shown improved wound healing and…
- Trial name
- NCT01459666
- Testing
- Dysport (abobotulinumtoxinA), Bacteriostatic 0.9% Sodium Chloride (vehicle)
- Where
- 2 sites in United States
- Volunteers
- 9 people
- Sponsor
- University Hospitals Cleveland Medical Center
Nonmelanoma Skin Cancer, Basal Cell Carcinoma
Vitamin D Effects on Immune Microenvironment of Nonmelanoma Skin Cancer After Photodynamic Therapy (PDT)
This research study is for people who have been diagnosed with a nonmelanoma skin cancer (either basal cell carcinoma or squamous cell carcinoma) and are planning to receive either Mohs surgery or ED\&C (electrodessication \&…
- Conditions
- Nonmelanoma Skin Cancer, Basal Cell Carcinoma, Squamous Cell Carcinoma
- Trial name
- NCT07241585
- Testing
- Vitamin D (VitD), Photodynamic therapy (PDT), Mohs surgery or electrodessication & curettage (ED&C) (standard of care)
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Case Comprehensive Cancer Center
Postoperative Pain, Acute, Skin Cancer
Meloxicam in Mohs Micrographic Surgery
The goal of this clinical trial is to explore alternative methods of postoperative pain control in Mohs micrographic surgery. The main aims are: To provide more information to the Mohs surgery community regarding postoperative…
- Trial name
- NCT07200544
- Testing
- Meloxicam 7.5 mg, Meloxicam 15 mg, Acetaminophen 500mg
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Oklahoma
Basal Cell Carcinoma, Squamous Cell Carcinoma
Serum Concentration of Lidocaine After Local Injection During Mohs Micrographic Surgery
The primary objective of this study is to (1) determine whether local injection of lidocaine used during Mohs surgery will elevate serum lidocaine concentrations to a level that could cause systemic symptoms and (2) determine…
- Trial name
- NCT00793169
- Testing
- Blood Draw
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Northwestern University
Wounds and Injuries, Burns
Clinical Registry Collecting Real World Evidence on Wound Care Treatments
The proposed registry Sponsor (Siddhey LLC) will collect data on various wound treatments in real life settings. Data collection will facilitate the analysis of the safety and efficacy of wound treatments.
- Conditions
- Wounds and Injuries, Burns, Mohs Surgery, Diabetic Foot Ulcer Mixed
- Trial name
- SIDDX (NCT06328010)
- Testing
- Various types of wound care treatments
- Where
- 12 sites in United States
- Volunteers
- 5,000 people
- Sponsor
- Siddhey LLC
Non-Melanoma Skin Cancer
Experience of Non-Melanoma Skin Cancer (NMSC) Mohs Surgery Project
Mohs surgery excises non-melanoma skin cancer tumors of the head and neck while preserving maximum healthy tissue, an advantageous characteristic when dealing with the cosmetic and functional cervifacial region.
- Trial name
- NCT01452984
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Lidocaine, Bupivacaine
Comparing the Efficacy of Local Anesthetics in Mohs Surgery
Mohs surgery is a very effective option in removing non-melanoma skin cancers, as the tissue being removed is analyzed the same day.
- Conditions
- Lidocaine, Bupivacaine, Mohs Surgery, Anesthetic
- Trial name
- NCT03871478
- Testing
- Lidocaine, Bupivacaine, Lidocaine and Bupivacaine
- Where
- Canada
- Volunteers
- 105 people
- Sponsor
- Ottawa Hospital Research Institute
Anxiety, Surgery
Pre-operative Consultation on Patient Anxiety and First-time Mohs Micrographic Surgery
To determine if in-office pre-operative consultation has a significant effect on the anxiety level and overall post-operative satisfaction of patients undergoing first time Mohs surgery
- Trial name
- NCT04612491
- Testing
- Pre-operative Consultation
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of California, Davis
Cicatrix
Comparison of Fast-Absorbing Sutures for Mohs Surgery
This study is being carried out to assess equivalence of scar outcome for two absorbable sutures used for wound closure on the face in dermatologic surgery: rapidly absorbable polyglactin 910 (VicrylRapide™) and fast-absorbing…
- Trial name
- NCT02334917
- Testing
- Surgical wound closure with superficial absorbable sutures
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Skin Cancer, Mohs Micrographic Surgery
Mohs Micrographic Surgery and Reconstruction in the Optum Insurance Claims Database
Mohs micrographic surgery (MMS) followed by skin reconstruction has been widely accepted for treatment of many skin cancers. To further characterize the trends in MMS and reconstruction for skin cancer, a retrospective analysis…
- Conditions
- Skin Cancer, Mohs Micrographic Surgery, Interpolated Flap Repair
- Trial name
- NCT04117373
- Where
- United States
- Sponsor
- University of Pennsylvania
Tissue Expander Disorder, Stress Strain Curve
Use of a Novel Device for Stretch Relaxation During Mohs Surgery
Closure of cutaneous defects is associated with many common and serious problems. For example, Mohs surgery involves the removal of skin and other soft tissues that have been proven to be infiltrated with cancer.
- Conditions
- Tissue Expander Disorder, Stress Strain Curve, Tissue Expansion, Mohs Surgery
- Trial name
- NCT03586960
- Testing
- Peak Force Measurement
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Silver Falls Dermatology
Basal Cell Carcinoma
Checking Wether the m-ALA Cream Could Mark Correctly the Borders of BCC's Tumors
Correlation between Mohs surgery and microscopic fluorescence photometry in determination of histological borders in Basal Cell Carcinoma .
- Trial name
- NCT00449358
- Testing
- apply methyl-ALA cream
- Where
- Israel
- Volunteers
- 32 people
- Sponsor
- Assuta Hospital Systems
Suture, Suture Dermatologic
Effect of Petrolatum Coating on Fast-absorbing Gut Suture
This study is designed to evaluate the effect of using petrolatum to coat gut suture. This coating is commonly performed to make the suture more easy to handle; however, it was unknown if it affects the absorption rate of the…
- Conditions
- Suture, Suture Dermatologic, Mohs Micrographic Surgery, Suture Techniques
- Trial name
- NCT07127029
- Testing
- Petrolatum coating of fast-absorbing gut suture
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- San Antonio Uniformed Services Health Education Consortium
Mohs Surgery
Briagen Observational Study
This research study is evaluating a study product called Briagen™ as a possible treatment for wound healing after Mohs procedure.
- Trial name
- BOS (NCT04090970)
- Testing
- Briagen
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Gemstone Biotherapeutics
Basal Cell Carcinoma, Squamous Cell Carcinoma
Reflectance Confocal Microscopy of Wounds During Moh's Surgery: Feasibility Testing of a Mosaicing Algorithm for Intraoperative Imaging of Cancer Margins
The purpose of this study is to evaluate a new instrument that shines light and takes digital pictures of skin. The goal is to develop a technique that may enable fast and accurate assessment of surgical margins in the excision…
- Trial name
- NCT01872130
- Where
- 4 sites in United States
- Volunteers
- 45 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Carcinoma, Basal Cell
A Randomised Study Comparing Tissue Conservation in Conventional Versus Mohs' Surgery of Basal Cell Carcinoma
We have compared to types of surgery to assess which one leaves the smaller surgical defect.
- Trial name
- NCT00571363
- Testing
- standard surgery, Mohs micrographic surgery
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- NHS Tayside
Quality of Life
Integrative Care and Acupuncture in MOHS Surgery
MOHS method is an effective surgical technique to remove skin cancerous tumors in the head-neck area. Patients undergoing MOHS surgery are struggled with emotional stress during the day of surgery, due to fear of significant…
- Trial name
- NCT03569982
- Testing
- Integrative medicine care
- Where
- Israel
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center
Skin Cancer, Skin Wound
Preoperative Image-based Education Effect on Postoperative Satisfaction of Patients Undergoing First-time Dermatologic Surgery
This research study aims to understand whether visual and written education on wound appearance can improve patients' experience and understanding of what their wound will look like following dermatologic surgery.
- Trial name
- NCT05643755
- Testing
- Preoperative image-based education
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Skin Cancer Excision Site, Basal Cell Carcinoma
Impact of Dysport on PMFF Donor Scar
The purpose of this research study is to investigate the effect of pre-operative injections of Dysport (Abobotulinumtoxin-A, commonly known as "Botox") on the cosmetic appearance of and overall satisfaction with study…
- Conditions
- Skin Cancer Excision Site, Basal Cell Carcinoma, Squamous Cell Carcinoma, Melanoma
- Trial name
- NCT07720726
- Testing
- Abobotulinumtoxin-A, Control- Saline injection
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Vanderbilt University Medical Center