Clinical trials: Modified Radical Mastectomy
Regional Anesthesia Morbidity
Serratus Anterior Plane Block and Costotransverse Block for Analgesia Following Modified Radical Mastectomy Surgeries
Adequate pain management following modified radical mastectomy (MRM) is crucial for early ambulation and patient satisfaction. Breast cancer is the most common malignancy in females, with an increasing incidence in recent years.
- Trial name
- NCT06260397
- Testing
- serratus anterior plane block, costotransverse block, patient controlled analgesia
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Breast Cancer
Single vs. Double Drain in Modified Radical Mastectomy
Seroma is a common complication following modified radical mastectomy(MRM). Closed drainage is used routinely to reduce incidence of seroma.
- Trial name
- NCT02411617
- Testing
- Drain
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Memon Medical Institute
Acute Pain
Analgesic Efficacy of Magnesium Sulphate as an Adjuvant to Levobupivacaine in Erector Spinae Block for Acute Pain Management in Modified Radical Mastectomy
To evaluate the analgesic efficacy of magnesium sulphate as adjuvants to levobupivacaine in erector spinae plane block in modified radical mastectomy surgery for acute pain management
- Trial name
- NCT04732390
- Testing
- erector spinae block with bupivacaine, erector spinae block with bupivacaine and magnesium sulphate
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- South Egypt Cancer Institute
Covid19, Breast Cancer Stage
COVID-19 Pandemic: Effect on Management of Patients With Breast Cancer
The objective was to find out the impact of COVID-19 on stage of breast cancer at presentation and its effects on overall onco-surgical management.
- Conditions
- Covid19, Breast Cancer Stage, Isolation, Social, Locally Advanced Breast Cancer
- Trial name
- COVID-19 (NCT04929964)
- Testing
- MRM , Toilet Mastectomy , BCS
- Where
- Pakistan
- Volunteers
- 87 people
- Sponsor
- Mehwish Mooghal , MBBS
Breast Cancer Surgery, Young Adult Females
Sexual Functıon in Young Women After Breast Cancer Surgery
The aim of this observational study was to analyse sexual function in young women after breast cancer surgery. The main question it aims to answer is Sexual function in young women after breast cancer surgery changes during the…
- Trial name
- NCT06966791
- Testing
- No intervention will be performed as part of this study. However, regardless of the study, all participants will have breast cancer surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- ATİYE KAŞ ÖZDEMİR
Postoperative Pain, Breast Cancer
Comparison of Erector Spinae Plane Block With Serratus Anterior Plane Block for Breast Surgery
Breast cancer is by far the world's most common cancer among women and the most common cause of female death from cancer worldwide. It's worldwide incidence is 43.4 in 100.000 while in Egypt is 48.8 in 100.000.
- Trial name
- NCT03579524
- Testing
- Erector Spinae Plane Block, Serratus Anterior Plane Block
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Fayoum University Hospital
Comparing of 2 Different Volumes in ESPB in Patients Undergoing MRM
Comparing the Perioperative Analgesic Effect of Two Different Volumes of Local Anesthetic Solution in Erector Spinae Plane Block in Patients Undergoing Modified Radical Mastectomy
The aim of this study is to compare and evaluate the analgesic effects of ultrasound-guided Erector Spinae Plane block using low volumes and high concentrations versus high volumes and low concentrations in patients undergoing…
- Trial name
- NCT05813158
- Testing
- Group 1(low concentration-high volume bupivacaine US guided Erector Spinae Plane block), Group 2(high concentration-low volumecbupivacaine US guided Erector Spinae Plane block)
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Cairo University
Postoperative Pain, Breast Cancer
RISS Versus SPSIP Block in Modified Radical Mastectomy
This prospective randomized double-blind controlled trial aims to compare the postoperative analgesic efficacy and dermatomal spread of rhomboid intercostal-subserratus plane (RISS) block and serratus posterior superior…
- Trial name
- RSMRM (NCT07659990)
- Testing
- Rhomboid Intercostal-Subserratus Plane Block, Serratus Posterior Superior Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ferit Yetik
Modified Radical Mastectomy, Postoperative Analgesia
Mid-point Transverse Process to Pleura Block VS Serratus Anterior Plane Block for Postoperative Analgesia After Modified Radical Mastectomy
This study aimed to compare the analgesic efficacy of ultrasound-guided mid-point transverse process-to-pleura block versus serratus anterior plane block after unilateral modified radical mastectomy.
- Conditions
- Modified Radical Mastectomy, Postoperative Analgesia, Mid-point Transverse Process to Pleura Block, Serratus Anterior Plane Block
- Trial name
- NCT06625879
- Testing
- Serratus Anterior Plane Block (SAPB), Midpoint transverse process to pleura (MTP) block
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Postoperative Pain Following Modified Radical Mastectomy for Breast Cancer
Ultrasound-guided Thoracic Interfascial Plane Nerve Block Versus Erector Spinae Plane Block for Pain Control After Modified Radical Mastectomy
This study compares two methods of local pain control in patients undergoing Modified Radical Mastectomy, a common surgery for breast cancer( tumor in the breast) treatment.
- Trial name
- NCT06548646
- Testing
- Thoracic Interfascial Plane Block, Erector Spinae Plane Block
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Safie ramez tewfeik abd el moneim
Breast Neoplasm Female, Postoperative Pain Management
PECS II vs. MTP for Analgesia After MRM
This randomized controlled study aims to compare the analgesic efficacy of the ultrasound-guided modified pectoral nerve block (PECS II) and the midpoint transverse process to pleura (MTP) block in female patients undergoing…
- Trial name
- NCT06187909
- Testing
- PECS II BLOCK, MTP BLOCK
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Ain Shams University
Breast Cancer
Dexamethasone Versus Dexmedetomidine as Adjuncts to Serratus Anterior Plane Block
Modified radical mastectomy is the most commonly performed surgical approach for breast cancer. The procedure enables surgeons to remove the main tumor mass, adjacent glandular tissue and regional lymph nodes.
- Trial name
- NCT06300099
- Testing
- Dexamethasone, Dexmedetomidine
- Volunteers
- 126 people
- Sponsor
- Al-Azhar University
Pain, Postoperative
Analgesic Efficacy of Ultrasound Guided Erector Spinae Block for Modified Radical Mastectomy
To compare the analgesic efficacy of dexmedetomidine and magnesium sulphate as adjuvants to levobupivacaine in erector spinae plane block in modified radical mastectomy surgery for acute and chronic pain management.
- Trial name
- NCT04732364
- Testing
- ultrasound guided erector spinae plan block using bupivacaine for modified radical mastectomy, ultrasound guided erector spinae plan block with bupivacaine and Dexmetonidine for modified radical mastectomy, ultrasound guided erector spinae plan block with bupivacaine and magnesium slphate for modified radical mastectomy
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- South Egypt Cancer Institute
Breast Cancer
Efficacy of Ketamine Added to Local Anesthetic in Modified Pectoral Block for Management of Postoperative Pain
This study aims to compare the analgesic efficacy and safety of local bupivacaine alone versus bupivacaine plus ketamine in ultrasound guided modified Pecs block in patients undergoing breast cancer surgery.
- Trial name
- NCT02620371
- Testing
- modified pectoral block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Breast Cancer, Post Operative Pain
Perioperative Mirogabalin for Pain Relief After Modified Radical Mastectomy
This study aims to evaluate whether perioperative mirogabalin can reduce postoperative pain and morphine consumption in female patients undergoing modified radical mastectomy for breast cancer.
- Trial name
- NCT07880821
- Testing
- Mirogabalin
- Volunteers
- 50 people
- Sponsor
- Cairo University
Seroma Following Procedure, Infections
Single Versus Double Drains in the Axillary and Pectoral Regions After Modified Radical Mastectomy
Normally, after this surgery, skin is stitched in the usual simple way, with no quilting, and two drains are put in to remove serosa, one under the arm and one on the chest.
- Conditions
- Seroma Following Procedure, Infections, Pain, Postoperative
- Trial name
- SVDD (NCT07512141)
- Testing
- Double drains will be placed, A single drain will be placed
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Sindh Institute of Urology and Transplantation
Ketamine, Pecs Block, Topical Wound Instillation , Modefied Radical Mastectomy
Comparative Study of Ketamine Added to Bupivacaine in PECS Block Versus Topical Wound Instillation on Post Operative Analgesia in Modified Radical Mastectomy Surgery
Comparative study of ketamine added to bupivacaine in PECS block versus topical wound instillation on post operative analgesia in modified radical mastectomy surgery
- Trial name
- NCT05410158
- Testing
- Ketamine in PECS block versus topical wound instillation
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Postoperative Pain, Breast Cancer
Erector Spinae Plane Block Versus Serratus Plane Block for Breast Surgery
Serratus plane block (SPB) was first described in 2013 by Blanco and designed to primarily block the thoracic intercostal nerves.
- Trial name
- NCT03538483
- Testing
- Bupivacaine Hcl 0.25% Inj, Bupivacaine HCl Inj 0.25%
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ataturk University
Modified Radical Mastectomy
Effect of ERAS and Upper Limb Exercise on LoS After Modified Radical Mastectomy
The goal of this clinical trial is to learn if Enhanced Recovery After Surgery (ERAS) protocol and upper limb exercise shorten the length of stay (LoS) in adults after modified radical mastectomy (MRM) surgery.
- Trial name
- NCT07574372
- Testing
- Enhanced Recovery After Surgery, Upper Limb Exercise
- Where
- Indonesia
- Volunteers
- 24 people
- Sponsor
- Prof. R. D. Kandou General Hospital
Mastectomy, Rhomboid Intercostal Block
The Efficacy of Ultrasound-Guided Rhomboid Intercostal Block Versus Serratus Plane Block in Mastectomy.
The aim of this study is to evaluate analgesic efficacy of ultrasound-guided rhomboid plane block or serratus plane block versus Intravenous opioid in patients undergoing modified radical mastectomy.
- Conditions
- Mastectomy, Rhomboid Intercostal Block, Serratus Plane Block
- Trial name
- NCT05156775
- Testing
- Serratus Plane Block (SPB), Rhomboid intercostal nerve block (RIB)
- Where
- Egypt
- Volunteers
- 105 people
- Sponsor
- Tanta University