Clinical trials: Mobility Limitation
Parkinson's Disease (PD)
Pilot Study of Robotic Spinal Mobilization in Parkinson's Disease
This interventional pilot study will evaluate the safety and clinical efficacy of robotic spinal mobilization in community-dwelling adults with Parkinson's Disease (PD).
- Trial name
- NCT07376122
- Testing
- BackHug Robotic Spinal Mobilization System
- Volunteers
- 30 people
- Sponsor
- Pacla Medical Limited
Mobility Limitation, Overweight or Obesity
Functional Fitness for Overweight or Obese Adults With Mobility Disabilities
Over 64 million people in the U.S. have a permanent disability, with mobility-related disability (MRD) representing the most prevalent disability type (13.7%).
- Conditions
- Mobility Limitation, Overweight or Obesity, Physical Disability
- Trial name
- COBRE Pilot (NCT05880966)
- Testing
- Functional Fitness
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Kansas
Mobility Limitation, Frailty
Assisted Ambulation to Improve Health Outcomes for Older Medical Inpatients
The investigator proposes to conduct a randomized trial of supervised ambulation delivered by mobility technician (MT) up to three times daily, including weekends, to hospitalized medical patients.
- Conditions
- Mobility Limitation, Frailty, Hospital Acquired Condition, Weakness, Muscle
- Trial name
- NCT05725928
- Testing
- Mobility technician
- Where
- 5 sites in United States
- Volunteers
- 3,000 people
- Sponsor
- The Cleveland Clinic
Mobility Limitation
Optimizing Protein Intake in Older Americans With Mobility Limitations
This will be a randomized, placebo-controlled, parallel group, double blind, clinical trial in community dwelling, older men, 65 years of age or older, who have mobility limitation and low protein intake.
- Trial name
- OPTIMen (NCT01275365)
- Testing
- Testosterone enanthate
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Brigham and Women's Hospital
Adhesive Capsulitis, Frozen Shoulder
Clinical Study for the Treatment of Adhesive Capsulitis of the Shoulder
The objectives of this study are to assess the safety, effectiveness, and immunogenicity of AA4500 in the treatment of adhesive capsulitis.
- Trial name
- AC (NCT02006719)
- Testing
- Collagenase Clostridium Histolyticum
- Where
- 46 sites in United States, Australia
- Volunteers
- 322 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Difficulty Walking
Spatio-temporal Parameters of Walking in Patients Hospitalized in Acute Geriatrics
The prevalence of walking disorders in the elderly is high. These can lead to falls which represent a major public health issue in terms of hospitalization, morbidity and cost.
- Trial name
- PST (NCT05152069)
- Where
- France
- Volunteers
- 67 people
- Sponsor
- University Hospital, Strasbourg, France
Parkinson Disease, Freezing of Gait
Use of CereGate Therapy for Freezing of Gait in PD
A Multi-Center, Controlled Study to Evaluate Use of CereGate Therapy to Reduce Freezing of Gait in Participants Diagnosed with Parkinson's Disease.
- Conditions
- Parkinson Disease, Freezing of Gait, Deep Brain Stimulation
- Trial name
- NCT05292794
- Testing
- CereGate Software; BSN cDBS Programmer; BSN Burst Programmer
- Where
- 7 sites in United States
- Volunteers
- 41 people
- Sponsor
- CereGate Inc.
Cerebral Palsy, Gait Disorders
The Effects of Exoskeletal Robot-Assisted Gait Training on Children With Cerebral Palsy: A Pilot Study
Cerebral Palsy (CP) is a complex neurodevelopmental disorder caused by early brain injury, leading to motor impairments such as muscle weakness, stiffness, and gait instability, which impact daily functioning.
- Conditions
- Cerebral Palsy, Gait Disorders, Gait Disorders in Children, Gait Disorders, Neurologic
- Trial name
- NCT05759182
- Testing
- Powered Exoskeleton Gait Training
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- COSMO ROBOTICS CO., Ltd
Aging, Fall Risk
Implementation of Routine Walking Speed Measurements in Older Veterans
Walking speed is a powerful predictor of mortality and adverse health consequences (e.g. fall or hospitalization) in older adults.
- Conditions
- Aging, Fall Risk, Mobility Limitation
- Trial name
- NCT07513805
- Testing
- Usual Care, FASTER
- Where
- United States
- Volunteers
- 10,500 people
- Sponsor
- VA Office of Research and Development
Fatigue, Walking, Difficulty
Neurophysiological Effects of Transcutaneous Electrical Nerve Stimulation in Persons With MS
Transcutaneous Electrical Nerve Stimulation (TENS) is a treatment that could potentially reduce walking problems and fatigue in persons with Multiple Sclerosis.
- Conditions
- Fatigue, Walking, Difficulty, Multiple Sclerosis
- Trial name
- NCT06432686
- Testing
- Transcutaneous Electrical Nerve Stimulation, Movement
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Pain, Acute Pain
Mobilization With Movement in Distal Radial Fractures
Distal radius fractures (DRF) are the most common upper extremity disorders encountered in clinical practice. With an understanding of the mechanics of distal radius fractures, surgical intervention, and bone healing, the…
- Conditions
- Pain, Acute Pain, Mobility Limitation
- Trial name
- NCT05976724
- Testing
- TENS, exercise, Mulligan mobilisation
- Where
- Turkey (Türkiye)
- Volunteers
- 53 people
- Sponsor
- Ahi Evran University Education and Research Hospital
Post Stroke, Mobility
Effect of Modified Constraint-induced Movement Therapy Combined With Virtual Reality on Mobility in Post-stroke Patients: A Randomized Control Trial
This study investigates the effectiveness of combining m-CIMT and VR to improve mobility in post-stroke patients. A non-blinded randomized controlled trial will be conducted with 32 participants divided equally into experimental…
- Conditions
- Post Stroke, Mobility, Balance
- Trial name
- NCT06975904
- Testing
- m-CIMT with VR exer-games by Kinect Xbox 360, m-CIMT with Task-Specific Functional Training
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Foundation University Islamabad
Difficulty Walking
EPIC WheelS Feasibility Study
Many older adults have difficulty walking. A wheelchair can improve their participation but older adults typically receive little wheelchair training.
- Trial name
- NCT01740635
- Testing
- EPIC WheelS Training Program
- Where
- 2 sites in Canada
- Volunteers
- 20 people
- Sponsor
- University of British Columbia
Telerehabilitation, COPD
Long-term Home-based Exercise for Patients With COPD: the COPDtoParis Project
This randomised controlled trial (RCT) aims to investigate the effect of long-term, interactive home-based cycle-exercise on patients with Chronic Obstructive Pulmonary Disease (COPD) after a COPD exacerbation requiring…
- Conditions
- Telerehabilitation, COPD, Quality of Life, Mobility Limitation
- Trial name
- COPDtoParis (NCT06235502)
- Testing
- Home-based cycle-exercise for COPD patients, Standard of Care
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Aalborg University Hospital
Fibromyalgia, Back Pain
Effects of Dry Needling on Spinal Mobility and Trigger Points in Patients With Fibromyalgia Syndrome.
This study evaluates the effect of Dry Needling on Spinal Mobility and Trigger Points in Patients with Fibromyalgia Syndrome.
- Trial name
- NCT02380807
- Testing
- Dry Needling, Cross Tape Therapy
- Where
- Spain
- Volunteers
- 66 people
- Sponsor
- Universidad de Almeria
Stroke, Walking, Difficulty
Agonist and Antagonist Muscle Activations in the Lower Limbs During Walking After Central Nervous System Injury
The retrospective study investigates the part of responsibility of neuromuscular disorders associated with chronic hemiparesis in walking impairment.
- Conditions
- Stroke, Walking, Difficulty, Spasticity/Paresis
- Trial name
- NEUROGAIT (NCT06107556)
- Testing
- Gait analysis
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Henri Mondor University Hospital
Erb's Palsy
Effects of Modified Constraint-induced Movement Therapy With and Without Electrical Stimulation in Erb's Palsy
ERB's palsy is an injury of upper section of the brachial plexus (C5-6) leading to an internally rotated and adducted shoulder and a pronated forearm.
- Trial name
- NCT06303427
- Testing
- Modified constraint-induced movement therapy, Electrical stimulation
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Mobility Limitation
Effectiveness of the On the Move Group Exercise Program to Improve Mobility in Community-dwelling Older Adults
The purpose of this study is to test the effectiveness of On the Move (OTM) in terms of improving mobility among 502 older adults in 44 senior community centers and to evaluate intervention fidelity, including adherence and…
- Trial name
- NCT05126355
- Testing
- On the Move group exercise
- Where
- United States
- Volunteers
- 529 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Postmastectomy Lymphedema Syndrome, Pain
Massage for Post Breast Surgery
The aims of this study are to determine the effectiveness of myofascial massage specific to the breast/chest/shoulder area in reducing self-reported pain and increasing mobility among patients who have undergone a mastectomy or…
- Conditions
- Postmastectomy Lymphedema Syndrome, Pain, Shoulder Mobility Impairment, Breast Surgery
- Trial name
- NCT02250898
- Testing
- Myofascial Massage Therapy, Global Relaxation Massage
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Duchenne Muscular Dystrophy, Ambulation Difficulty
Cultural Adaptation, Validity, and Reliability of the Turkish Version of North Star Ambulatory Assessment
The aim of this study is to translate the "North Star Ambulatory Assessment (NSAA)" scale into Turkish and make its cultural adaptation and to demonstrate the reliability and validity of the Turkish version in patients with…
- Conditions
- Duchenne Muscular Dystrophy, Ambulation Difficulty, Ambulation Disorder, Neurologic
- Trial name
- NCT05549999
- Testing
- North Star Ambulatory Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- Hacettepe University