Clinical trials: Mobility
Surgical Wound, Bilateral Total Knee Arthroplasty
Evaluating Edema and Range of Motion Using Negative Pressure Therapy vs. Standard Surgical Dressing in Bilateral TKA
This study will compare the effects of closed incision negative pressure dressing vs. standard of care silver dressing on lower limb swelling after bilateral primary total knee arthroplasty.
- Conditions
- Surgical Wound, Bilateral Total Knee Arthroplasty, Wounds and Injuries, Joint Diseases
- Trial name
- ENABLE (NCT04712019)
- Testing
- Closed Incision Negative Pressure Therapy (ciNPT), Standard Silver-containing Dressing
- Where
- 6 sites in United States
- Volunteers
- 10 people
- Sponsor
- Solventum US LLC
Spastic Cerebral Palsy
Short Term Follow-up of a Botulinum Toxin Intervention in Children With Spastic Cerebral Palsy
This study investigates the effect of integrated Botulinum Neurotoxin A (BoNT) treatment on morphologic muscle and tendon properties, spasticity, joint stiffness, joint range of motion, muscle strength, gait and gross motor…
- Trial name
- NCT05126693
- Testing
- Botulinum Toxin treatment combined with a post-BoNT intensive physical therapy period guided by individualized treatment goals.
- Where
- Belgium
- Volunteers
- 61 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Aging, Mobility Limitation
Yoga to Prevent Mobility Limitations in Older Adults
The loss of mobility during aging impacts independence and leads to further disability, morbidity, and reduced life expectancy. The study objective was to examine the feasibility and safety of conducting a randomized controlled…
- Conditions
- Aging, Mobility Limitation, Sedentary Lifestyle
- Trial name
- NCT03544879
- Testing
- Yoga Intervention, Healthy Aging Education
- Volunteers
- 46 people
- Sponsor
- University of California, San Diego
Lower Extremity Amputation
Community Walking Trials: Comparing Prosthetic Feet
The purpose of the study is to obtain performance measurements and participant feedback about use of an investigational prosthetic foot compared to the participant's usual prosthetic foot.
- Trial name
- NCT03703232
- Testing
- Investigational prosthetic foot
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Washington
Cardiac Rehabilitation, Health Coaching
Targeted Health Coaching to Improve Physical Activity Post-Structured Cardiac Rehabilitation
To identify factors and triggers influencing physical activity (PA) participation after structured cardiac rehabilitation (CR) among older adults who have enrolled in a center-based CR program, and compare the effects of a…
- Conditions
- Cardiac Rehabilitation, Health Coaching, Physical Activity
- Trial name
- Target-CR (NCT05773287)
- Testing
- Targeted Health Coaching Group, Standard Care Group
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Duke University
Adhesive Capsulitis, Frozen Shoulder
Clinical Study for the Treatment of Adhesive Capsulitis of the Shoulder
The objectives of this study are to assess the safety, effectiveness, and immunogenicity of AA4500 in the treatment of adhesive capsulitis.
- Trial name
- AC (NCT02006719)
- Testing
- Collagenase Clostridium Histolyticum
- Where
- 46 sites in United States, Australia
- Volunteers
- 322 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Cerebral Palsy, Child, Preschool
Effect of Power Wheelchairs on the Development and Function of Young Children With Severe Physical Disabilities
Self-produced locomotion often is limited in children with cerebral palsy and other conditions that cause severe motor impairments.
- Trial name
- NCT01115998
- Testing
- Power wheelchair, No power wheelchairs
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Oklahoma
Obesity, Dysmobility
Multimodel Exercise and Weight Loss in Older Obese Veterans With Dysmobility
Obesity is a major risk factor for mobility problems in older adults and many older adults use a walking aid to help with their mobility.
- Trial name
- RISE (NCT02806336)
- Testing
- Multi Modal Balance Training (MMBI), Weight Loss (WL)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- VA Office of Research and Development
Weakness, Muscle, Delirium in Old Age
YOOMI: Effect of Gamified Physical Therapy Exercise Software on Inpatient Mobility
Patients admitted to the hospital often develop functional impairments due to being in bed most of the day. Each day of bedrest leads to significant muscle loss.
- Conditions
- Weakness, Muscle, Delirium in Old Age, Muscle Atrophy or Weakness, Muscle Loss
- Trial name
- YOOMI (NCT05815017)
- Testing
- Yoomi Physical Therapy Software
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Parkinsonian Signs in Older Persons
Neurobiological Drivers of Mobility Resilience: The Dopaminergic System - Placebo-Controlled Arm
Walking with age becomes both slower and less 'automated', requiring more attention and brain resources. As a result, older adults have a greater risk of negative outcomes and falls.
- Trial name
- RES (NCT06219915)
- Testing
- Carbidopa 25 mg, Carbidopa-Levodopa 25/100 mg
- Where
- 2 sites in United States
- Volunteers
- 13 people
- Sponsor
- University of Michigan
Foot Pain
Orthofeet: A Prospective Proof of Concept Trial to Evaluate an Innovative Pain Relief Footwear
The purpose of this prospective randomized crossover study is to evaluate the effectiveness of a new pain relief footwear, Orthofeet, in reducing foot pain and improving daily physical activity.
- Trial name
- NCT05434078
- Testing
- Orthofeet Shoes
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Bijan Najafi, PhD