Clinical trials: Mixed Method Implementation Study
Cataract (Post-operative Cataract Surgery Follow-up)
Vision Center Determinants of Cataract Follow-Up in Rural India
Cataract remains the leading cause of avoidable blindness in India despite substantial expansion of surgical services over the past two decades.
- Trial name
- NCT07513402
- Testing
- Follow-Up Strengthening Intervention Framework
- Volunteers
- 150 people
- Sponsor
- Seva Canada Society
Generative Artificial Intelligence
Implementation of a Blended Online and Offline Teaching Model
This study aims to design, implement, and evaluate a blended online and offline teaching model for Internal Medicine Nursing, integrating generative artificial intelligence (GAI), a virtual simulation platform, card-based…
- Trial name
- NCT07189611
- Testing
- A blended online and offline teaching model for internal medicine nursing practice based on generative artificial intelligence
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Hengxu Wang
Schistosomiasis in Children, Social Acceptance
Adoption of L-PZQ for Schistosomiasis by Endemic Counties - Social Science Research Study
Knowledge, acceptability and perception of paediatric schistosomiasis and its treatment will be explored through a social science-driven mixed-methods approach within three endemic countries: Kenya, Uganda and Côte d'Ivoire.
- Trial name
- ADOPT (NCT05350462)
- Testing
- Community pilot L-PZQ distribution - intervention is NOT part of this observational study
- Where
- 3 sites in Côte d’Ivoire, Kenya and 1 more
- Volunteers
- 225 people
- Sponsor
- Technical University of Munich
HIV Infections
Electronic Capture of Adherence Barriers for HIV Care
Adherence to antiretroviral therapy (ART) remains problematic. Our team has thus developed a new patient-reported measure of barriers to ART adherence (the I-Score) which will be completed by HIV patients through the Opal patient…
- Trial name
- CTNPT039 (NCT04702412)
- Testing
- The Opal patient portal and smartphone application combined with the I-Score patient-reported outcome measure
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Implementation Research, Artificial Intelligence (AI)
Barriers and Facilitators to Nursing Record With AI Technology Application
The goal of this study is to examine the facilitators and barriers to the comprehensive implementation of AI technology in nursing documentation.
- Conditions
- Implementation Research, Artificial Intelligence (AI), Nursing Documentation Burden
- Trial name
- NCT07532343
- Testing
- AI-based technologies systems to assist with nursing record
- Where
- Taiwan
- Volunteers
- 271 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University Hospital
Perinatal Anxiety, Perinatal Depression
Pathways to Perinatal Mental Health Equity
Mental health conditions occurring during pregnancy and up to one year postpartum (the perinatal period) occur in 1 in 5 perinatal individuals.
- Conditions
- Perinatal Anxiety, Perinatal Depression, Social Determinants of Health (SDOH), Peer Support
- Trial name
- Pathways (NCT06790641)
- Testing
- Program in Support of Moms (PRISM), PSI Peer Support
- Where
- United States
- Volunteers
- 1,270 people
- Sponsor
- University of Massachusetts, Worcester
Substance Abuse Disorder, Dialectical Behavior Therapy
Implementing DBT in Short-Term SUD-treatment
The main objective of the study is to provide new knowledge about the implementation of DBT-informed environmental therapy in short-term substance use disorder (SUD) inpatient treatment.
- Conditions
- Substance Abuse Disorder, Dialectical Behavior Therapy, Emotion Management Skills
- Trial name
- NCT07693439
- Testing
- DBT-informed milieu therapy, Treatment as usual
- Where
- Norway
- Volunteers
- 82 people
- Sponsor
- Helse Møre og Romsdal HF
Palliative Care
Implementation of RELIEF for Patients With Palliative Care Needs
For patients with palliative care needs, access to care is constrained by health system resources and a requirement to visit their clinician for assessments.
- Trial name
- NCT05806255
- Testing
- The RELIEF App
- Volunteers
- 600 people
- Sponsor
- William Osler Health System
Parents, Children With Disabilities
ACT Together: Implementing a Web-Based Program With Brief Coaching for Parents of Children With Disabilities in Pediatric Outpatient Clinics
The goal of this clinical trial is to evaluate the feasibility, usability, and preliminary benefits of implementing ACT Together for parents of children with disabilities in pediatric outpatient clinics.
- Conditions
- Parents, Children With Disabilities, Stress, Depression
- Trial name
- NCT07360600
- Testing
- ACT Together
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of South Florida
Depression
Mixed Methods Implementation Evaluation of an Integrated Depression and Microfinance Program for Women in Vietnam
This is an implementation project to develop a model to support implementation of LIFE-DM, an evidence-based practice (EBP) program that integrates depression management with microfinance services to address both poverty and…
- Trial name
- LIFE-DM (NCT04218214)
- Testing
- LIFE-DM Group (Integrated Depression and Livelihood Group Intervention)
- Where
- 2 sites in Vietnam
- Volunteers
- 141 people
- Sponsor
- RAND
Health Behavior, Quality of Life
Feasibility and Implementation of a Healthy Lifestyles Program
Chronic conditions, such as obesity and diabetes, are increasing worldwide. Lifestyle changes (e.g., physical activity, healthy diet, sufficient sleep, managing stress, smoking cessation) are often recommended to prevent or…
- Conditions
- Health Behavior, Quality of Life, Chronic Disease, Health Promotion
- Trial name
- NCT03258138
- Testing
- Health and wellness learning sessions, Brainstorming group sessions, Individual sessions with a multidisciplinary health team
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- McMaster University
Low Back Pain
Evaluating the Impact of a Champion on Implementation of the Back Skills Training (BeST) Program in Canada
There is global recognition in clinical guidelines and governing bodies that low back pain (LBP) should be managed with a biopsychosocial approach.
- Trial name
- NCT04377529
- Testing
- Local Champion
- Where
- Canada
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Memorial University of Newfoundland
HIV Infections, ART
Accelerated ART Initiation for PWHIV Who Are Out of Care
The main purpose of the study is to evaluate the effectiveness, of the ACCELERATE model of care to achieve HIV viral suppression at Week 24.
- Conditions
- HIV Infections, ART, Noncompliance, Patient
- Trial name
- ACCELERATE (NCT06374758)
- Testing
- The Accelerate model of care, bictegravir/emtricitabine/tenofovir alafenamide 50/200/25 mg
- Where
- 4 sites in United States
- Volunteers
- 120 people
- Sponsor
- University of Missouri-Columbia
Exercise, Disability Physical
Testing the Implementation of Movement-to-Music in a Community Fitness Center and Blended Onsite and Teleexercise Class
To prepare for a large scale-up study, the goal of this pilot implementation trial is to examine the feasibility of Movement-to-Music (M2M©) delivery mechanisms through two channels: 1) a group-based M2M© program conducted onsite…
- Trial name
- NCT03991273
- Testing
- Y-M2M©, B-M2M©
- Sponsor
- University of Alabama at Birmingham
Eating Disorders in Adolescence, Transition of Care
Feasibility of the TransitionED Framework for Youth and Young Adults With Eating Disorders
Moving from pediatric (children's) health care to adult health care can be challenging for youth and young adults with eating disorders.
- Trial name
- TransitionED 3 (NCT07518641)
- Testing
- TransitionED Healthcare Transition Framework
- Where
- 2 sites in Canada
- Volunteers
- 60 people
- Sponsor
- McMaster University
Focus of Study: Accurate Clinical Measurement and Diagnosis
TIMCIs: A Hybrid Type 2 Study of Next-generation Pulse Oximeters
This study aims to provide evidence on next-generation clinical measurement tools through a mixed methods diagnostic accuracy and implementation study in Kenya, Senegal, Tanzania, and Uttar Pradesh, India.
- Trial name
- NCT05527990
- Testing
- Multimodal PO
- Where
- 2 sites in Kenya
- Volunteers
- 650 people
- Sponsor
- PATH
Nurse Practitioners, Implementation Research
Role Development, Implementation and Evaluation of Nurse Practitioners
Hospitals face new challenges in providing sustainable high quality care as the prevalence of chronic conditions, multimorbidity and the complexity of care increases.
- Conditions
- Nurse Practitioners, Implementation Research, Quality of Care
- Trial name
- NUPRA-DI (NCT05520203)
- Testing
- Care provided by the Nurse Practitioner
- Where
- 2 sites in Belgium
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Leukemia, Multiple Mieloma
The Implementation of the Go Wish Game to Promote Advance Care Planning in Onco- Hematologic Disease
This is a mixed-method, device-free and drug-free multicenter interventional study. The study aims at facilitating end-of-life conversations within the doctor-patient relationship through the use of the Go Wish Game (GWG) and…
- Conditions
- Leukemia, Multiple Mieloma, Advanced Solid Tumors, Lymphoma
- Trial name
- OHGW-ACP (NCT06795815)
- Testing
- Go Wish Game
- Where
- Italy
- Volunteers
- 75 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Major Depressive Disorder
Enhanced Measurement-Based Care Effectiveness for Depression (EMBED) Study
Measurement-based care (MBC) is an evidence-based practice that incorporates routine outcome assessment using validated rating scales to guide collaborative clinical decision-making.
- Trial name
- EMBED (NCT05527951)
- Testing
- eMBC, standard MBC
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Shanghai Mental Health Center
Dementia, Dementia Alzheimers
Implementation of a Diagnostic Decision-aid for People With Memory Complaints and Their General Practitioners
In a mixed-methods design the investigators will study decision making processes and experiences regarding a diagnostic trajectory before and after the introduction of a patient decision aid for people with memory complaints…
- Conditions
- Dementia, Dementia Alzheimers, Dementia, Mild
- Trial name
- S-DeciDeD (NCT04531956)
- Testing
- Diagnostic decision aid s-decided
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- Maastricht University