Clinical trials: Miscarriage
Miscarriage
Could Colour Dopper Improve the Diagnosis of Retained Placental Fragments After Second Trimester Miscarriage ?
Value of pelvi- abdominal ultrasound and Doppler in diagnosis of retained products of conception after second trimester miscarriage to select who will benefit from surgical evacuations or conservative management.
- Trial name
- NCT02419300
- Testing
- ultrasoungraphy
- Where
- Egypt
- Volunteers
- 82 people
- Sponsor
- Ain Shams University
Pneumonia, Pleural Effusion
Evaluation of Ultra-portable Ultrasound in General Practice
This is an interventional multi-centre study comparing two groups of general practitioners with or without an ultrasound scanner over a period of 6 months.
- Conditions
- Pneumonia, Pleural Effusion, Renal Colic, Hepatic Colic or Cholecystitis
- Trial name
- EPEMedG (NCT04127149)
- Testing
- Ultrasound scan
- Where
- France
- Volunteers
- 166 people
- Sponsor
- Hospices Civils de Lyon
Down Syndrome
Non Invasive Prenatal Testing of Down Syndrome
This is a randomized controlled trial in women at risk following combined prenatal screening for Down Syndrome. Women will be asked about their preferences between NIPT and routine prenatal diagnosis based on a dedicated…
- Trial name
- SAFE 21 (NCT02127515)
- Testing
- Non Invasive Prenatal Testing, Invasive Prenatal Testing
- Where
- France
- Volunteers
- 2,111 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pregnancy, Infertility
Selenium Supplementation in Pregnancy
Serum levels of isolated anti-thyroperoxidase (TPOab) and anti-thyreoglobulin (Tgab) autoantibodies are strongly associated with an increased risk of miscarriage and premature deliveries in euthyroid pregnant women.
- Conditions
- Pregnancy, Infertility, Auto-immune Thyroiditis
- Trial name
- Serena (NCT01465867)
- Testing
- Selenium, Selenium + L-Thyroxine (LT4)
- Where
- 11 sites in Italy
- Volunteers
- 56 people
- Sponsor
- University of Roma La Sapienza
Missed Abortion
Repeated Doses of Misoprostol for Medical Treatment of Missed Miscarriage
Missed abortion is a condition where the fetus has perished but the miscarriage is not expelled. Women often present at a routine ultrasound or with a slight brownish discharge.
- Trial name
- NCT01615224
- Testing
- misoprostol
- Where
- Sweden
- Volunteers
- 23 people
- Sponsor
- Kristina Gemzell Danielsson
Uterine Septum
Reproductive Outcomes Following Uterine Septum Resection
Nowadays, there is little data to validate the performance of surgical hysteroscopies in the case of septate uterus, particularly in the case of incidental discoveries.
- Trial name
- UTER-SEPTUM (NCT05139446)
- Where
- France
- Volunteers
- 400 people
- Sponsor
- University Hospital, Strasbourg, France
Infertility, Aneuploidy
The Effect of Acupuncture on Pregnancy Rates in Women Undergoing in Vitro Fertilization With Preimplantation Genetic Screening
While IVF offers an effective treatment for infertility, a significant proportion of IVF cycles still result in failed implantation and early miscarriage.
- Trial name
- NCT03981120
- Testing
- Laser and Traditional Acupuncture
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Miscarriage
Feasibility Study of a Coping Intervention for Recurrent Miscarriage
Some women experience the pain of miscarriage on numerous occasions. Studies show that these women experience feelings of anxiety and distress during the early stages of a new pregnancy as they worry another miscarriage will…
- Trial name
- NCT02989220
- Testing
- Positive Reappraisal Coping Intervention
- Where
- United Kingdom
- Volunteers
- 75 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Effect of Drug
Analgesia From Conscious Sedation Versus Paracervical Block for Manual Vacuum Aspiration
Miscarriage is one of the major causes of early pregnancy losses. Incomplete miscarriage is a major cause of maternal morbidity and mortality.
- Trial name
- NCT06539143
- Testing
- Lidocaine
- Where
- Nigeria
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Darlington-Peter Chibuzor Ugoji
Miscarriage, Grief
Couples Miscarriage Healing Project:Randomized Trial
This is a randomized trial of three caring based interventions to see if we can help couples heal after miscarriage. All three are based on Swanson's theory of caring and Meaning of Miscarriage Model.
- Conditions
- Miscarriage, Grief, Pregnancy Loss
- Trial name
- NCT00194844
- Testing
- Nurse Caring, Self Caring, Combined Caring
- Where
- United States
- Volunteers
- 682 people, healthy volunteers welcome
- Sponsor
- University of Washington
Spontaneous Abortion in First Trimester
Comparing Buccal and Vaginal Misoprostol in Management of Early Pregnancy Loss
First trimester miscarriages are common. When the failed pregnancy does not pass spontaneously on its own, it is called a missed abortion.
- Trial name
- NCT02141555
- Testing
- Vaginal Misoprostol, Buccal Misoprostol
- Where
- 2 sites in United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Subclinical Hypothyroidism, Infertility
Levothyroxine Treatment and IVF Outcomes in Women With Subclinical Hypothyroidism: A Target Trial Emulation
Subclinical hypothyroidism (SCH) is defined by elevated thyroid-stimulating hormone (TSH) with normal free thyroxine (fT4) levels.
- Conditions
- Subclinical Hypothyroidism, Infertility, Assisted Reproductive Technology, In Vitro Fertilization (IVF)
- Trial name
- LESI (NCT07257250)
- Where
- 2 sites in Vietnam
- Volunteers
- 900 people
- Sponsor
- Mỹ Đức Hospital
Abortion, Habitual
Pr-conceptional Progesterone for Unexplained Recurrent Miscarriage
In women with unexplained recurrent miscarriages, progesterone (400 mg pessaries, twice daily), started soon as possible at luteal phase and after a positive pregnancy test and continued to 28 weeks of gestation, compared to…
- Trial name
- NCT01670929
- Testing
- Progesterone
- Where
- Egypt
- Volunteers
- 700 people
- Sponsor
- Woman's Health University Hospital, Egypt
Infertility
Pregnancy Outcomes With a GnRH Antagonist Protocol Versus GnRH-Agonist Protocol in ICSI Cycles
Cycles with GnRH agonist and GnRH antagonist were compared and main outcome measures were the number of oocytes retrieved, injected and fertilized, embryos transferred, and clinical pregnancy and miscarriage rates, were analized.
- Trial name
- NCT00485537
- Testing
- oocyte retrieval and ICSI procedure
- Where
- Brazil
- Volunteers
- 2,005 people
- Sponsor
- Clinic and Research Center in Human Reproduction Roger Abdelmassih
Frozen Embryo Transfer, Polycystic Ovarian Disease
Letrozole Versus Hormonal Preparation in Frozen Cycles of PCOS Patients.
One of the indications of freezing is to reduce the risk of ovarian hyperstimulation syndrome particularly in polycystic ovarian disease (PCOS) women.
- Conditions
- Frozen Embryo Transfer, Polycystic Ovarian Disease, Letrozole, Hormone Replacement Therapy
- Trial name
- NCT05168865
- Testing
- Letrozole 2.5mg
- Sponsor
- Dubai Fertility Center
Vitamin D Deficiency, Recurrent Miscarriage
The Cohort Study of the Correlation Between Serum 25(OH)D Level and Pregnancy Outcome
The objective of this single-center prospective observational study is to clarify the trend of maternal serum 25(OH)D levels before pregnancy and during pregnancy, and to explore the correlation between serum 25(OH)D levels and…
- Conditions
- Vitamin D Deficiency, Recurrent Miscarriage, Pregnancy Related
- Trial name
- NCT05824897
- Testing
- Serum levels of vitamin D
- Where
- China
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Aimin Zhao
Miscarriage
Misoprostol for Management of Women With an Incomplete Miscarriage
Miscarriage is defined as the spontaneous loss of a pregnancy before 24 weeks gestation, that is, before fetal viability. The clinical signs of miscarriage are usually vaginal bleeding associated with abdominal pain and cramping.
- Trial name
- NCT05088720
- Testing
- misoprostol 800 µg, misoprostol 400 µg
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Aswan University Hospital
Interchromosomal Breakpoint, Infertility
Interchromosomal Insertion Carriers PGT-SR
Interchromosomal insertions (IT) are rare and complex structural rearrangements. Theoretically, the risk to have a child to term with a malformation or mental retardation can reach 50% related to the proportion of unbalanced…
- Trial name
- NCT04978402
- Where
- France
- Volunteers
- 3 people
- Sponsor
- University Hospital, Montpellier
Pregnancy
Correlation Between PIF Maternal Serum Levels and Pregnancy Outcome
PIF: biomarker of pregnancy, miscarriage, premature birth, preeclampsia, placenta accreta. Except for serum hCG, no pregnancy-complication markers are widely employed to predict the need for medical intervention.
- Trial name
- PIFBlood1 (NCT01805102)
- Where
- 5 sites in United States, France and 1 more
- Volunteers
- 500 people
- Sponsor
- BioIncept LLC
IUCD Complication
Isonicotinic Acid Hydrazide (INH) Pretreatment With Misoprostol Versus Misoprostol Alone in Missed Abortion
The primary endpoint was the success rate of adjuvant isonicotinic acid hydrazide (INH) and misoprostol versus misoprostol alone for medical termination of first-trimester pregnancy.
- Trial name
- NCT04500002
- Testing
- Isonicotinic Acid Hydrazide, Misoprostol
- Where
- Egypt
- Volunteers
- 240 people
- Sponsor
- Aswan University Hospital