Clinical trials: Minority Stress
Depression, Anxiety
Efficacy of a Brief Intervention to Improve Sexual and Gender Minorities' Mental Health: Randomized Controlled Trial.
Experiences of violence, from micro to physical aggressions, have a deleterious impact on mental health. According to the Minority Stress Theory, unfavorable social conditions (such as anticipated and experienced discrimination…
- Conditions
- Depression, Anxiety, Psychological Distress, Social Phobia
- Trial name
- ESCREVA-SE (NCT05349877)
- Testing
- Expressive writing, Self-affirmation
- Where
- Brazil
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidade Católica do Rio Grande do Sul
Cancer, Breast Cancer
Improving Survivorship Among Minority Cancer Dyads
This proposed intervention centers on improving survivorship outcomes among African American and Latinx cancer survivor and caregiver dyads. As a result, there will be four major outcomes.
- Conditions
- Cancer, Breast Cancer, Colon Cancer, Caregiver Burnout
- Trial name
- NCT04685551
- Testing
- Change in knowledge, motivation, skills, and resources
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Charles Drew University of Medicine and Science
Depression, Suicidality
Development and Preliminary Trial of a Brief, Portable Health Intervention for Rural Sexual Minority Emerging Adults
The purpose of this study is to test the feasibility of writing interventions specifically designed for lesbian, gay, and bisexual (LGB) emerging adults (ages 18-29) that are aimed at improving the outcomes: depression…
- Conditions
- Depression, Suicidality, Substance Abuse, HIV
- Trial name
- Project LEAP (NCT03751020)
- Testing
- Expressive Writing (EW) Intervention, Self-Affirmation (SA) Intervention, Control
- Where
- 3 sites in United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Yale University
Gender Dysphoria
Trans Care: An Online Intervention to Reduce Symptoms of Gender Dysphoria
The current project aims to improve the well-being of trans and nonbinary (TNB) individuals through an online intervention (Trans Care) targeting the reduction of symptoms of gender dysphoria.
- Trial name
- NCT05884307
- Testing
- Trans Care Web App
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Heart Diseases, Type2 Diabetes
Psychosocial, Environmental, and Chronic Disease Trends in Puerto Rico
The overall goal is to identify trends and longitudinal associations in psychosocial, food-related, and cardiometabolic risk factors that can guide public health priorities and future research needs aimed at reducing…
- Conditions
- Heart Diseases, Type2 Diabetes, Hypertension, Obesity
- Trial name
- PROSPECT (NCT03794531)
- Where
- Puerto Rico
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Sexual and Gender Minorities, Pregnancy Complications
Physical and Mental Health Among Sexual and Gender Minorities During Pregnancy, Birth and Postpartum
Mental illness increases the risk of adverse birth outcomes (e.g. preterm birth), obstetric complications (e.g. emergency caesarean, birth injuries), and birth trauma.
- Conditions
- Sexual and Gender Minorities, Pregnancy Complications, Obstetric Complication, Psychological Trauma
- Trial name
- NCT05354284
- Testing
- online questionnaire
- Where
- Sweden
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Linkoeping University
HIV, Acquired Immunodeficiency Syndrome
A Unified Intervention for Young Gay and Bisexual Men's Minority Stress, Mental Health, and HIV Risk
The intent of the proposed randomized controlled trial is to test the efficacy of a principle-based, transdiagnostic cognitive behavioral therapy (CBT) intervention that addresses the pathways through which minority stress…
- Trial name
- NCT02929069
- Testing
- ESTEEM, CMHT, VCT
- Where
- 2 sites in United States
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Yale University
Stress, Physiological, Ethanol Intoxication
Internalized Stress in Relation to Alcohol Consumption
The proposed study uses an experimental design to establish causal support for the role of internalized stress, pertaining to uncertainty with regard to one's sexual orientation, in contributing to heavy drinking behavior.
- Conditions
- Stress, Physiological, Ethanol Intoxication, Distress, Emotional
- Trial name
- NCT06091189
- Testing
- Relevant Trier Social Stressor Test (TSST), Ethanol, Irrelevant Trier Social Stressor Test (TSST)
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Emotional Problem, Pain, Back
Minority Joy and Minority Stress in Trans People: an Intervention Study
The aim of this project is to get a better understanding of transgender and gender non-conforming (TGNC) people's experiences of minority joy and minority stress over time.
- Conditions
- Emotional Problem, Pain, Back, Quality of Life
- Trial name
- NCT05693324
- Testing
- Minority stress
- Where
- Sweden
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
Stress, Depression
Latina Friends Motivating the Soul (ALMA)
Latina immigrant women are particularly vulnerable to depression and anxiety due to the social and economic stressors they face, including high levels of poverty, low levels of education, family obligations, exposure to violence…
- Conditions
- Stress, Depression, Anxiety
- Trial name
- NCT03749278
- Testing
- Latina Friends Motivating the Soul (ALMA)
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Washington
Cigarette Smoking
Smoking, Stress, HIV and Mobile Technology
The present investigation aims to address disparities in cigarette use outcomes among Black/African American adults with HIV. The specific aims of this study are: (1) To modify a recently developed, culturally adapted, mobile…
- Trial name
- NCT05709002
- Testing
- MASP+, Control
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Houston
Stress, Externalizing Symptoms
Teenage Health and Wellness Study
This study evaluates the effects of mindfulness on physiological stress mechanisms implicated in externalizing behaviors and symptoms of affective and traumatic stress among urban adolescents.
- Conditions
- Stress, Externalizing Symptoms, Depression Symptoms, Anxiety
- Trial name
- THAW (NCT03989934)
- Testing
- The Mind in Action, Healthy Topics
- Where
- United States
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Penn State University
Minority Stress, Psychological Stress
Effect of Ashwagandha Root Extract on Stress, Anxiety, and Sleep Quality in Adults Experiencing Minority Stress
Sexual and gender minority adults often experience elevated levels of chronic stress due to stigma, discrimination, and social adversity, commonly referred to as minority stress.
- Conditions
- Minority Stress, Psychological Stress, Anxiety
- Trial name
- NCT07441070
- Testing
- Ashwagandha Root Extract
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- SF Research Institute, Inc.
Heavy Drinking, Mental Health Issue
Affirmative Psychotherapy for Sexual Minority Women's Mental and Behavioral Health
The purpose of this 2-arm randomized controlled trial is to assess the efficacy of a 10-session lesbian, gay, bisexual, transgender, and queer (LGBTQ)-affirmative cognitive-behavioral psychotherapy (CBT) delivered via telehealth…
- Trial name
- EQuIP (NCT05509166)
- Testing
- LGBTQ-affirmative Cognitive Behavioral Therapy, LGBTQ-affirmative Treatment-As-Usual
- Where
- United States
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Yale University
Minority Stress
Minority Stress Counseling for LGBTQ+ Individuals
Lesbian, gay, bisexual, transgender, and queer+ (LGBTQ+) individuals experience a breadth of mental health disparities. Reducing these disparities is an area of key psychological research.
- Trial name
- MST (NCT06614868)
- Testing
- Acceptance and Commitment Therapy, Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Alcohol Drinking, Violence in Adolescence
The Healthy Families Bright Futures Program
The goal of this clinical trial is to learn about an online group program (Healthy Families Bright Futures program) for LGBTQ+ teens and their caregivers.
- Trial name
- NCT06309134
- Testing
- Healthy Families Bright Futures Program
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Colorado Springs
Infant Mortality, Infant Death
Today Not Tomorrow Pregnancy and Infant Support Program (TNT- PISP)
This pilot project aims to implement and investigate the feasibility and acceptability of a unique community based prenatal care and support model for African American women and infants in Dane County.
- Conditions
- Infant Mortality, Infant Death, Racial Bias, Prenatal Stress
- Trial name
- NCT04100577
- Testing
- Today Not Tomorrrow Pregnancy and Infant Support Program
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Stress Disorders, Post-Traumatic, Drinking Heavy
Project QueST 2023: Queer Survivors of Trauma
This study aims to test the initial efficacy of tailored online writing interventions specifically designed for sexual minority women, transgender individuals, and/or nonbinary people to target the primary outcomes: posttraumatic…
- Trial name
- QueST2023 (NCT05569915)
- Testing
- Trauma Expressive Writing, Stigma Expressive Writing, Control
- Where
- United States
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Syracuse University
Alcohol Consumption, Violence, Domestic
Proximal Effects of Alcohol on Same-Sex Intimate Partner Violence
We will recruit sexual and gender minority couples to complete 56 days of daily surveys in order to evaluate (1) the impact of COVID-19 stress and sexual and gender minority stress on heavy episodic drinking and intimate partner…
- Conditions
- Alcohol Consumption, Violence, Domestic, Stress, Psychological, Aggression
- Trial name
- PASSION (NCT04625465)
- Testing
- CBT Text Messaging, Attention Control Text Messaging
- Where
- United States
- Volunteers
- 474 people, healthy volunteers welcome
- Sponsor
- Georgia State University
Stress Reaction, Sexuality
Effects of Self-Compassion Practice on Stress Reactivity Among Sexual Minority Women
This project will test the ability of brief self-compassion training to attenuate physiological and subjective responses to induced stress among sexual minority women, transgender people, and nonbinary people.
- Conditions
- Stress Reaction, Sexuality, Compassion
- Trial name
- NCT05949060
- Testing
- Compassion Intervention
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Syracuse University