Clinical trials: Migraines
Migraine
Psychosomatic Factors Influencing the Efficacy of Holistic Care for Migraine
This research project aims at exploring the psychosomatic factors that influence and moderate the efficacy of holistic care and personalized treatment for migraine patients. It is a prospective longitudinal observational study.
- Trial name
- NCT06334237
- Testing
- personalized treatment
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Changhua Christian Hospital
Neck Pain, Migraine
Common Pain Mechanisms in Migraine, Migraine-Related Neck Pain, and Lower Back Pain: A Cross Sectional Study
Migraine is one of the primary headache disorders with a high prevalence worldwide, leading to significant disability and reduced quality of life.
- Conditions
- Neck Pain, Migraine, Low Back Pain
- Trial name
- NCT07567300
- Where
- Turkey (Türkiye)
- Volunteers
- 179 people
- Sponsor
- Bozok University
Migraine
Comparing Efficacy and Safety of 2 Dose Regimens of Subcutaneous Administration of TEV-48125 Versus Placebo for the Preventive Treatment of Chronic Migraine
The study is being conducted to evaluate two doses of TEV-48125 in adult patients with chronic migraine
- Trial name
- NCT02621931
- Testing
- Fremanezumab
- Where
- 273 sites in United States, Canada and 7 more
- Volunteers
- 1,130 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Migraine
Head-to-head Study of Erenumab Against Topiramate in Patients With Episodic and Chronic Migraine
This study used a single-cohort, 2-treatment arm, parallel-group randomized, double-blind, double-dummy design in adult patients with episodic migraine and chronic migraine, who had to be either naïve or not suitable for or could…
- Trial name
- HER-MES (NCT03828539)
- Testing
- Erenumab, Topiramate
- Where
- 79 sites in Germany
- Volunteers
- 777 people
- Sponsor
- Novartis Pharmaceuticals
Migraine, Abdominal Pain
Migraine and Recurrent Abdominal Pain in Children
This study will evaluate a new model for assessing and treating migraine and recurrent abdominal pain in children. The model combines behavioral techniques such as relaxation training with biologic components such as thermal…
- Trial name
- NCT00060619
- Testing
- thermal biofeedback, relaxation training, cognitive coping skills
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
MELAS Syndrome, Lebers Hereditory Optic Neuropathy With Extra Ocular Symptoms (LHON-Plus)
A Basket Clinical Study to Assess Glycerol Tributyrate in Patients With Mitochondrial Encephalopathy, Lactic Acidosis, Stroke-like Episodes (MELAS) or Leber's Hereditary Optic Neuropathy-Plus (LHON-Plus)
This is a parallel arm non-randomized dose-escalation, open-label basket exploratory phase 1 clinical trial where Mitochondrial encephalopathy, lactic acidosis, stroke-like episodes (MELAS) and Leber's hereditary optic…
- Trial name
- NCT06792500
- Testing
- Glycerol Tributyrate
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- George Washington University
Migraine
A Phase 1 Study to Evaluate the Safety, Tolerability, and Immunogenicity of UB-313 in Healthy Participants
This first in-human (FIH) study of UB-313, an anti-calcitonin gene-related peptide based immunotherapeutic candidate, is designed to assess the safety, tolerability, and immunogenicity of 4 selected UB-313 dose regimens in…
- Trial name
- NCT05477095
- Testing
- UB-313
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Vaxxinity, Inc.
Headache, Migraine
Investigating the Frequency and Phenotype of Headaches Associated With Fasting During the Month of Ramadan.
Headaches are more common in the month of Ramadan in patients who already suffer from migraine. The object of the present study is investigate the frequency in the Ramadan month .
- Trial name
- NCT04804995
- Testing
- There is no intervention.
- Where
- Denmark
- Volunteers
- 134 people
- Sponsor
- Danish Headache Center
Migraine With or Without Aura
Eletriptan for the Treatment of Migraine in Patients With Previous Poor Response or Tolerance to Oral Sumatriptan
To determine the tolerability and efficacy of eletriptan in patients who had discontinued oral sumatriptan due to lack of efficacy or intolerable adverse events (AEs) during previous clinical treatment (not a controlled trial).
- Trial name
- NCT01989936
- Testing
- Eletriptan 40 mg, Eletriptan 80 mg
- Where
- 43 sites in Denmark, Finland and 3 more
- Volunteers
- 446 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Migraine, Headaches
Effect on Migraine Frequency of Combined Anti-oxidant Therapy: The MIGRANT Study.
Migraine affects 15% of Western Australians and is a leading cause of suffering and disability in our community (1,2). Research suggests that inflammation of the brain's coverings (meninges) by nerve cell inflammation and the…
- Trial name
- MIGRANT (NCT02629536)
- Testing
- N-acetyl cysteine 600 mg, VitE 250 IU, VitC 500 mg tablet
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Notre Dame Australia
Migraine With Aura
Tonabersat in the Prophylaxis of Migraine With Aura
Overall trial objectives: 1. Can treatment with tonabersat reduce the number of days with aura and/or migraine headache in patients with migraine with aura 2.
- Trial name
- NCT00332007
- Testing
- Tonabersat
- Where
- Denmark
- Volunteers
- 39 people
- Sponsor
- Minster Research Ltd
Migraine
A Proof of Concept Alleviating the Symptoms of Photosensitive Migraine.
This proof of concept clinical study will investigate the efficacy of active lens with frame in alleviating the symptoms of migraine which are caused by photosensitivity.
- Trial name
- NCT04904328
- Testing
- Lumishade® Active Lens
- Volunteers
- 77 people
- Sponsor
- Mitsui Chemicals, Inc.
Migraine
A Study of Rizatriptan for the Treatment of Acute Migraine in Patients on Topiramate for Migraine Prophylaxis
This study will provide additional efficacy data for rizatriptan when used for an acute migraine attack in patients already taking topiramate for migraine prophylaxis.
- Trial name
- NCT00812006
- Testing
- rizatriptan benzoate
- Volunteers
- 108 people
- Sponsor
- Organon and Co
Migraine Disorders
Study to Evaluate the Safety, Tolerability, and Blood Pressure Effect of an Oral Dose of Sumatriptan Alone and in Combination With MK-0974 (Telcagepant) in Migraine Patients (0974-026)
Study to understand the effects of migraine treatments on blood pressure in participants with migraine. The primary hypothesis is that the effect on semi-recumbent mean arterial pressure following the coadministration of…
- Trial name
- NCT00701389
- Testing
- telcagepant potassium, sumatriptan
- Volunteers
- 24 people
- Sponsor
- Merck Sharp & Dohme LLC
Migraine, Atrial Fibrillation
Effect of Catheter Ablation on Clinical Course of Migraine in AF Patients With or Without Previous History of Migraine
The purpose of this prospective study is to evaluate the effect of catheter ablation on incidence, prevalence and disease-severity of migraine in AF patients undergoing ablation, with or without a history of migraine.
- Trial name
- CONFIRM (NCT01391091)
- Testing
- Radiofrequency catheter ablation
- Where
- United States
- Volunteers
- 173 people
- Sponsor
- Texas Cardiac Arrhythmia Research Foundation
Borderline Personality Disorder
Clinical Research Study to Evaluate Selegiline in the Treatment of Borderline Personality Disorder
Selegiline is superior to placebo in improving psychological and physical functioning in patients with Borderline Personality Disorder.
- Trial name
- NCT01912391
- Testing
- Selegiline
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mood and Anxiety Research, Inc
Migraine
Chronic Pain and Conditioned Pain Modulation After on Line-behavioral Approach
Chronic pain is a disabling condition associated with progressive changes and decline in psychological wellbeing. According with a modern conceptualization, pain has to be considered a biopsychosocial disorder where biological…
- Trial name
- Be-Home-Pain (NCT04859374)
- Testing
- Mindfullness, treatment as usual (TAU) (pharmacological)
- Volunteers
- 35 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Migraine, Pain, Shoulder
Effects of MTRPs Therapy in Migraine.
Case series, repeated-measures design, pilot study. Adult, female, migraine patients underwent seven Ischemic Compression Myofascial Trigger Points (IC-MTrPs) therapy sessions.
- Conditions
- Migraine, Pain, Shoulder, Trapezius Muscle Strain Left, Trapezius Muscle Strain Right
- Trial name
- MTRPs (NCT05646160)
- Testing
- Ischemic Compression of Myofascial Trigger Points (IC-MTRPs)
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Józef Piłsudski University of Physical Education
Migraine Without Aura
Ibuprofen in Migraine Patients
In this study, the investigators planned to compare the effectiveness of an intravenous ibuprofen against an intravenous dexketoprofen among patients (18-65 years) who were admitted to the emergency department (ED) with acute…
- Trial name
- NCT04533568
- Testing
- Ibuprofen 400 mg, Dexketoprofen
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Kecioren Education and Training Hospital
Migraine
A Study of LY2951742 (Galcanezumab) in Japanese Participants With Migraine
The main purpose of this study is to evaluate the safety and effectiveness of the study drug known as Galcanezumab in Japanese participants with migraine.
- Trial name
- NCT02959190
- Testing
- Galcanezumab
- Where
- 44 sites in Japan
- Volunteers
- 311 people
- Sponsor
- Eli Lilly and Company