Clinical trials: Microvascular Perfusion
Stroke, Epilepsy
Coronary and Cerebral Microvascular Dysfunction in Neurological Diseases
Neurological and cardiovascular diseases are increasing in relative and absolute terms globally, and pose a major burden in terms of morbidity, mortality, quality of life and healthcare costs.
- Conditions
- Stroke, Epilepsy, Transient Global Amnesia (TGA)
- Trial name
- G-HeBra (NCT07009990)
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Ischemia
Ischemia and Reperfusion Injury in the Human: An Observational Study
We, the researchers at Lawson Health Research Institute, propose to investigate the impact of surgical ischemia and reperfusion on skeletal muscle microcirculation using a hand-held microscope.
- Trial name
- NCT00229047
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Coronary Artery Disease
Correlation Study of Imaging Data Acquired During CABG With Data Acquired in the Cath Lab
Visual assessment of a coronary artery narrowing (called stenosis) seen on angiography is conventionally used to infer how likely the stenosis will limit blood flow (called ischemia) under conditions of increased demand (e.g…
- Trial name
- PERSEUS (NCT02138305)
- Testing
- ComboMap XT Guidewire, 'SPY' NIRF During CABG
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- East Carolina University
Covid19, Multisystem Inflammatory Syndrome in Children (MIS-C)
Contrast Enhanced Ultrasound in COVID-19
Initial data from COVID-19 patients suggests that one of the primary causes of death is significant endothelial injury leading to blood clotting and impaired multiorgan microvascular perfusion.
- Trial name
- NCT04640038
- Testing
- Sulfur hexafluoride lipid-type A microspheres
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Children's Hospital of Philadelphia
Dizziness, Vertigo
Trental for the Treatment of Vertigo/Dizziness/Imbalance
Imbalance, dizziness and vertigo as a result of problems in the inner ear (vestibular dysfunction) are becoming increasingly more prevalent in Americans 40 years of age and older.
- Trial name
- NCT02592863
- Testing
- Pentoxifylline
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Missouri-Columbia
Biological Aging
Effects of Phytonutrients Upon Muscle Perfusion in Response to Feeding
This is a random order cross over design trial to evaluate the efficacy of select nutritional ingredients on enhancing muscle perfusion in response to an acute meal stimulus.
- Trial name
- NCT03213340
- Testing
- Catechin Cohort 1, Curcuminoid Cohort 2, Flavonoid Cohort 3
- Where
- United Kingdom
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Abbott Nutrition
Ischemic Heart Disease
Hyperbaric Oxygen Therapy in Patients With Chronic Stable Ischemic Heart Disease: An Option for Therapeutic Angiogenesis?
Hyperbaric oxygen therapy (HBOT) is proposed as a possible in vivo angiogenic stimulator for improving microvascular myocardial perfusion and anginal symptoms as assessed by myocardial perfusion imaging and angina questionnaire…
- Trial name
- NCT02760394
- Testing
- HBOT
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Assaf Harofeh MC
Microcirculatory Perfusion, ST Elevation Myocardial Infarction
Deferred or Immediate Stent Implantation Based on Microvascular Function in STEMI
Timely percutaneous coronary intervention (PCI) with stenting implantation is the current standard treatment for patients with ST-segment elevation myocardial infarction (STEMI).
- Trial name
- SALVAGE (NCT03581513)
- Testing
- Deferred or Immediate Stent Implantation
- Where
- 8 sites in China
- Volunteers
- 629 people
- Sponsor
- Harbin Medical University