Clinical trials: Microvascular Circulation
Aging, Sarcopenia
Effect of L-arginine on Microcirculation, Myogenesis and Angiogenesis Associated With Aging, Sarcopenia and Diabetes
This study aims was evaluated the effect of L-arginine on microcirculation, vasoreactivity / endothelial function and vascular smooth muscle of young and old women with Sarcopenia or Type 2 Diabetes Mellitus measured by Nailfold…
- Conditions
- Aging, Sarcopenia, Type 2 Diabetes, Microcirculation
- Trial name
- NCT04112875
- Testing
- L-arginine, Maltodextrin
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Microcirculation
The Effect of Photobiomodulation on Microvascular Blood Flow: The Role of Wavelength and Skin Temperature
The objective of this study is to assess peripheral microcirculatory hemodynamic responses to photobiomodulation in participants with normal circulation and with functional peripheral vasoconstriction, using noninvasive…
- Trial name
- PBM&MBF01 (NCT07338695)
- Testing
- Photobiomodulation - Blue Wavelength, Photobiomodulation - Near Infrared
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Afeka, The Tel-Aviv Academic College of Engineering
Cushing Syndrome, Hypercortisolism
Nailfold Capillaroscopy Evaluation in Cushing Syndrome Patients
This cross-sectional, single-center study will assess the microvascular function using a nailfold video-capillaroscopy in patients with endogenous Cushing syndrome.
- Trial name
- NCT04433819
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Marmara University
Severe Traumatic Brain Injury, Trauma
Impact of Severe Brain Injury on Neuro-vascular and Endothelial Regulation of Peripheral Microcirculation.
Severe brain injury (SBI) is one of the world's leading causes of death and disability in young adults, but its peripheral vascular consequences in humans are poorly understood.
- Trial name
- MicroTC (NCT04597879)
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Severe Sepsis
Effects of Acute Systemic Inflammation on Arterial Stiffness and Microcirculation.
This study aims to assess the effect of acute inflammation on arterial stiffness and microcirculation. Patients with severe sepsis will be compared with age-, sex- and cardiovascular risk factors-matched controls.
- Trial name
- IRIGA (NCT01556373)
- Testing
- NA : non interventional study
- Where
- 2 sites in France
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Chronic Kidney Disease Patients
Glycocalyx and Oxidative Stress in Endothelial Function (Part 1)
The primary research objective of the project is to determine the role of eGC in microvascular reactivity in CKD (cross-sectional study 1).
- Trial name
- GlikoOxEND (NCT07437729)
- Where
- Croatia
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Josip Juraj Strossmayer University of Osijek
Microcirculation
Establishing Normal Ranges of Microcirculatory Function as Determined by CytoCam-IDF Imaging
When infection strikes, the body's immune system reacts by producing chemicals in the bloodstream and changes in white blood cells to attack the infecting organism (bacteria, viruses or other organisms) and prevent it spreading.
- Trial name
- NCT03044483
- Testing
- Measurement of sublingual microcirculatory parameters
- Where
- United Kingdom
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- University Hospitals, Leicester
Microcirculation, Thermoregulation
Impact of Active Thermoregulation on the Microcirculation of Free Flaps
This study evaluates the impact of active thermoregulation on free flap microcirculation following free flap transfer. Thermoregulation is performed by passive warming, active warming (water circulation based device) and active…
- Conditions
- Microcirculation, Thermoregulation, Free Flap
- Trial name
- NCT02466594
- Testing
- Hilotherm Clinic®
- Where
- Germany
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Ulf Dornseifer, MD
Preeclampsia and Intrauterine Growth Restriction
Placental Insufficiency Microcirculation Quantification by Ultrafast Doppler (MICRODOPPLER PLACENTA)
To identify fetuses small for their gestational-age who have reached their appropriate growth potential from growth-restricted fetuses due to placental insufficiency is uneasy.
- Trial name
- NCT03860103
- Where
- France
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Stroke, Vascular Diseases
Passive Limb Movement Study
Stroke survivors have compromised vascular function which may contribute to secondary stroke risk, cardiovascular disease, and may limit their exercise tolerance.
- Conditions
- Stroke, Vascular Diseases, Ischemic
- Trial name
- PLM (NCT05935670)
- Testing
- Ischemic Conditioning
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Hypertension
Neural Mechanism of Aldosterone-induced Insulin Resistance
Patients with high aldosterone hormone have higher blood glucose than normal people. This study is being done to understand how aldosterone hormone affects the nerve activity that controls blood flow in the muscles and blood…
- Trial name
- NCT02102243
- Testing
- DEFINITY® infusion, Human Recombinant Regular Insulin infusion, Dextrose infusion
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Wanpen Vongpatanasin
HIV/AIDS
People Living With HIV/AIDS, Nitrate, Endotelial Function, Arterial Stiffness and Skeletal Muscle Oxygenation
Administration of antiretroviral therapy has brought benefits for infective human immunodeficiency virus-1 (HIV-1)-patients, reducing the number of AIDS-related morbidity and mortality.
- Trial name
- NCT03485248
- Testing
- Beetroot Juice
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Shock Wave and Nitric Oxide
Monitoring Effect Of Shock Wave On Microcirculation Changes In Type2 Diabetes Mellitus
The purpose of the study is to monitor the effect of low intensity extracorporeal shock wave therapy on impaired nitric oxide synthase and microcirculation changes in type 2 diabetes mellitus with peripheral neuropathy.
- Trial name
- NCT06159192
- Testing
- Low intensity extracorporeal shock wave
- Where
- 2 sites in Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- South Valley University