Clinical trials: Micronutrient Deficiency
Mortality Through Six Months of Age, Vitamin A Deficiency
Community Trial of Newborn Vitamin A Supplementation to Reduce Infant Mortality in Rural Bangladesh
The purpose of this trial is determine whether a 50,000 IU oral dose of vitamin A delivered to newborn infants within the first days of life, reduces six-month infant mortality by at least 15%.
- Trial name
- NCT00128557
- Testing
- vitamin A supplementation (15,000 ug retinol equivalents or 50,000 IU)
- Where
- Bangladesh
- Volunteers
- 15,937 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Protein Malnutrition, Vitamin Deficiency
Evaluation of Protein Intake and Micronutrient Supplementation After Bariatric Surgery
Obesity is a chronic disease in which accumulation of excess body fat can result in impaired health. In cases of severe obesity, weight loss surgery can be necessary as a treatment.
- Conditions
- Protein Malnutrition, Vitamin Deficiency, Mineral Deficiency, Trace Element Deficiency
- Trial name
- BOP (NCT04587076)
- Where
- Germany
- Volunteers
- 38 people
- Sponsor
- University Medicine Greifswald
Vitamin A Deficiency, Iron-deficiency
Effect of Household Use of Multiple Micronutrient-fortified Bouillon on Micronutrient Status Among Women and Children in Two Districts in the Northern Region of Ghana
Background: Micronutrient (MN) deficiencies are severe and widespread in West Africa, particularly among young children and women of reproductive age.
- Conditions
- Vitamin A Deficiency, Iron-deficiency, Folate Deficiency, Vitamin B 12 Deficiency
- Trial name
- NCT05178407
- Testing
- Multiple micronutrient-fortified bouillon cube, Control bouillon cube (iodine-only)
- Where
- Ghana
- Volunteers
- 2,372 people
- Sponsor
- University of California, Davis
Iodine Deficiency Disorders
RCT of Iodine-containing MNPs vs Oral Iodized Oil to Prevent Iodine Deficiency in Weaning Infants
In this study, two intervention strategies to address iodine deficiency and prevent iodine deficiency disorders in breast-fed weaning infants will be evaluated in a mild to moderate iodine-deficient population in Zamboanga del…
- Trial name
- NCT02421653
- Testing
- MNP90, MNP45, IODISED OIL
- Volunteers
- healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Vitamin A Deficiency, Maternal Mortality
Impact of Maternal Vitamin A or Beta-Carotene Supplementation on Maternal and Infant Mortality in Bangladesh
The purpose of this trial is to determine whether providing women with a weekly oral supplement of vitamin A, either preformed or as beta-carotene, at a dosage equivalent to a recommended intake from early pregnancy through three…
- Conditions
- Vitamin A Deficiency, Maternal Mortality, Infant Mortality
- Trial name
- NCT00198822
- Testing
- Vitamin A or Beta-Carotene Supplements
- Where
- 3 sites in United States, Bangladesh
- Volunteers
- 59,666 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Age-related Macular Degeneration, Vitamin D Deficiency
Omega 3 and Vitamin D Dosage in a Population With Moderate to High Risk of AMD
Objectives: The investigators conducted a prospective study in Belgium with the objective to determine the proportion of subjects identified at moderate-to-high risk for AMD, based on the STARS® questionnaire, in need of…
- Trial name
- OVID-AMD (NCT04482465)
- Testing
- blood sample
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Critical Illness, Nutritional Deficiency
Trace Element Repletion Following Severe Burn Injury
Major burn patients are characterized by large exudative losses of Cu, Se and Zn. Trace element (TE) repletion has been shown to improve clinical outcome.
- Conditions
- Critical Illness, Nutritional Deficiency, Trace Element Deficiency, Burn Injury
- Trial name
- NCT03204669
- Testing
- Trace elements replacement
- Where
- Switzerland
- Volunteers
- 139 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Environmental Enteric Dysfunction, Zinc Deficiency
Effects of EED on Zn Absorption and Retention in Children From a MNP
The overall objective is to determine the impact of EED on total daily zinc absorption of young Bangladeshi children (18-24 months of age) in an austere setting with high rates of diarrhea, stunting, and micro-nutrient…
- Trial name
- ZEED2 (NCT02758444)
- Testing
- Micronutrient Powder (MNP) + 15 mg Zn, MNP + 10 mg Zn, MNP + 5 mg Zn
- Where
- 2 sites in United States, Bangladesh
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Nutritional Status, Nutrient Deficiency
Challenges in Achieving Adequate Dietary Status of Women
The aim of the study is to investigate the dietary habits of women of reproductive age (20-49 years). We aim to obtain epidemiological data on the intake and adequacy of key macronutrients and micronutrients, as well as to…
- Conditions
- Nutritional Status, Nutrient Deficiency, Micronutrient Deficiency, Vitamin D Deficiency
- Trial name
- NutriFem (NCT06745817)
- Testing
- Assessement of nutritional status, Dermis density and thickness, Skin elasticity
- Where
- 3 sites in Slovenia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Institute of Nutrition, Slovenia (Nutris)
Folate Deficiency, Vitamin B 12 Deficiency
Effectiveness of Fortification With Folic Acid and Vitamin B12 Among Teenage Girls
Folic acid and vitamin B12 play an interdependent role in key cellular processes, namely deoxyribonucleic acid synthesis, cell division, red blood cell formation, and nervous system myelination.
- Conditions
- Folate Deficiency, Vitamin B 12 Deficiency, Anemia, Megaloblastic, Cognitive Development
- Trial name
- NCT06100146
- Testing
- Folic acid and vitamin B12 fortified flour, Unfortified cereal flour
- Where
- 2 sites in Ethiopia
- Volunteers
- 472 people, healthy volunteers welcome
- Sponsor
- University Ghent
Anemia, Iron Deficiency
Is Iron Deficiency the Cause of Anemia Among Women in Cambodia?
Globally, the most common cause of anemia is thought to be iron deficiency anemia (IDA). This was assumed to be the major cause of anemia in Cambodia, because Cambodian diets, which consist mainly of rice, lack iron-rich animal…
- Conditions
- Anemia, Iron Deficiency, Hemoglobin Disorder, Infection
- Trial name
- NCT02481375
- Testing
- Multiple micronutrients, Iron
- Where
- Cambodia
- Volunteers
- 809 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Nutrient Deficiency
Study of Multiply-fortified Salt Among Women of Reproductive Age and Preschool Children in India
Micronutrient (MN) deficiencies are highly prevalent in India, particularly among women of reproductive age (WRA) and preschool aged children (PSC).
- Trial name
- MFS (NCT05166980)
- Testing
- Mutiply-fortified salt, Iodized salt
- Where
- India
- Volunteers
- 1,389 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Vitamin A Deficiency, Iron Deficiency
Effect Of Multiple Biofortified Food Crops On Micronutrient Status And Immune Function Among Indian Infants and Their Mothers
In this study, meals based on multiple food crops (containing either biofortified or commercially-available food crops) will be fed to young children in Madanapalle, Andhra Pradesh, India over a period of nine months to measure…
- Conditions
- Vitamin A Deficiency, Iron Deficiency, Zinc Deficiency
- Trial name
- MBFC (NCT02648893)
- Testing
- Multiple biofortified food crops (MBFC-Exp), Commercially available non-fortified food crops (MBFC-C)
- Where
- 2 sites in India
- Volunteers
- 200 people
- Sponsor
- Cornell University
Nutritional Status, Iron-deficiency
Assessing Dietary Intake of Selected Food Components Using Short Questionnaires
The aim of the study is to validate short questionnaires for assessing dietary intake of selected food components, with a focus on dietary fibre and iron.
- Conditions
- Nutritional Status, Iron-deficiency, Diet
- Trial name
- NutriPlant/FFQ (NCT07442305)
- Testing
- 5d-PD: Nutritional intakes using 24-h food recalls, KV-PV: Dietary fibre intake, KV-Fe: Iron intake
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Institute of Nutrition, Slovenia (Nutris)
Micronutrient Deficiency, Cardiovascular Disease
Health2016: Monitoring Chronic Disease and Risk Factors in the General Population
Health2016 is a general population cross-sectional study aimed at completing af monitoring program for monitoring chronic disease and risk factors in the period 2006 to 2016.
- Conditions
- Micronutrient Deficiency, Cardiovascular Disease, Allergy, Respiratory Disease
- Trial name
- NCT02720809
- Where
- Denmark
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Glostrup University Hospital, Copenhagen
Protein-Energy Malnutrition, Anorexia
Energy Dense Formula to People Living in Old Peoples Home
Dietary intake in frail elderly is often lower than estimated needs due to the combined effects of the anorexia of ageing, frailty and the presence of acute and chronic disease.
- Conditions
- Protein-Energy Malnutrition, Anorexia, Weight Change
- Trial name
- NCT01259999
- Testing
- Calogen extra strawberry
- Where
- Sweden
- Volunteers
- 32 people
- Sponsor
- Karolinska University Hospital
Focus: Nutritional Deficiency
Sanitary Napkins for Urinary Assessment of Micronutrients
This study aims to find an easy urinary collection method for the assessment of urinary markers of micronutrient status.
- Trial name
- NCT05777356
- Testing
- Urine collection and assessment of dietary intake by food frequency questionaire
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Hohenheim
Stunting, Anemia
Effectiveness Study During the First 1,000 Days in Kenya
Malnutrition is a public health problem in Kenya, with 26% of children underfive years of age stunted, and 26% of pre-school children, 26% of women of reproductive age and 42% of pregnant women being anaemic, respectively.
- Conditions
- Stunting, Anemia, Micronutrient Deficiency
- Trial name
- NCT03558464
- Testing
- Intervention (integrated package), Control
- Where
- Kenya
- Volunteers
- 1,199 people, healthy volunteers welcome
- Sponsor
- Fabian Rohner
Bariatric Surgery
Multivitamin Support Following Bariatric Surgery
Bariatric surgery (BS), an effective treatment for severe obesity and its comorbidities, may result in micronutrient and vitamin deficiencies.
- Trial name
- NCT06152965
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Bioitalia srl
Iodine Deficiency, Iodine Deficiency Disorder
Iodine Status of Preschoolers Given Micronutrient Powder for 6 Months
Iodine deficiency remains widespread worldwide with children as among the vulnerable groups considering their stage of growth and development.
- Conditions
- Iodine Deficiency, Iodine Deficiency Disorder, Hypothyroidism
- Trial name
- MNP-CAR (NCT02280330)
- Testing
- MNP group
- Where
- Philippines
- Volunteers
- 396 people, healthy volunteers welcome
- Sponsor
- Nutrition Center of the Philippines