Clinical trials: Microcirculation
Thyroid Associated Orbitopathy
Changes in Orbital Macrovascular and Intraocular Microvascular Blood Flow After Orbital Decompression Surgery in Patients With Thyroid Eye Disease
This study aims to evaluate the effects of balanced orbital decompression surgery in patients with inactive thyroid-associated orbitopathy.
- Trial name
- BOD-VASC (NCT07393230)
- Testing
- Balanced Orbital Decompression Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Microcirculation, Photoplethysmography
Evaluation of Microcirculation With Photoplethysmography (Pulse Oximetry) in Healthy Volunteers and Ventilated Patients
The objective of this observational study is to explore microcirculation in healthy volunteers and in ventilated patients in the operating room and in critical care.
- Trial name
- NCT06141681
- Testing
- photoplethysmography
- Where
- Argentina
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hospital Privado de Comunidad de Mar del Plata
Acute Myocardial Infarction
Effect of Shexiang Tongxin Dropping Pills on Microcirculation in Patients With AMI
This study is a randomized, controlled clinical trial. Evaluation of microcirculation resistance by index of microcirculation resistance to explore the protective effect of Shexiang Tongxin dripping pills on microcirculation in…
- Trial name
- NCT04952259
- Testing
- Shexiang Tongxin Dropping Pills + routine treatment, routine treatment
- Volunteers
- 60 people
- Sponsor
- Peking University Third Hospital
Microcirculatory Status, Spectroscopic Analysis
Near-Infrared Spectroscopy Measurements in Chronic Obstructive Pulmonary Disease
Participants were selected based on three groups: healthy, chronic obstructive pulmonary disease, and chronic renal disease. NIRS was used to measure tissue oxygenation on the thenar region of the right hand.
- Conditions
- Microcirculatory Status, Spectroscopic Analysis, COPD, Renal Failure
- Trial name
- NIRS (NCT06976762)
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Local Skin Blood Flow
Reproducibility of Photobiomodulation Induced Changes in Local Skin Blood Flow in Healthy Subjects
This study investigated whether near-infrared photobiomodulation (PBM), a non-invasive light therapy, can consistently increase blood flow in the skin of healthy adults.
- Trial name
- PBM (NCT07809464)
- Testing
- Near-infrared photobiomodulation (NIR PBM), Control (heat)
- Where
- Norway
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Myocardial Ischemia
Clinical Study on the Correlation Between IMR（Index of Microcirculation Resistance） and FFR（Fractional Flow Reserve）
To study the effect of myocardial microcirculation disturbance on coronary flow reserve fraction, compare the evaluation value of IMR, FFR and QCA on myocardial ischemia, and discuss the correlation among them.
- Trial name
- NCT04224714
- Testing
- FFR
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The People's Hospital of Liaoning Province
Microcirculation of the Caput Femoris
Identification of the Microcirculation of the Caput Femoris After Fracture of the Femoral Neck
This project investigates wether the intra-capsular hematoma, that often occurs after fracture of the femural neck, decreases the capillary blood flow of the caput femoris.
- Trial name
- MicroFemNeck (NCT01483404)
- Testing
- Measurement with O2c
- Where
- Germany
- Sponsor
- RWTH Aachen University
STEMI, Coronary Microvascular Dysfunction
Super Saturated Oxygen (SSO2) Therapy in Patients With ST-segment Elevation Myocardial Infarction (STEMI) and Action on Coronary Microcirculation Dysfunction
The goal of this clinical trial is to demonstrate the improvement in Coronary Microcirculation Dysfunction (CMD) with Super Saturated Oxygene (SSO2) therapy in patients with anterior ST-segment Elevation Myocardial Infarction…
- Trial name
- IC-HOT-MICRO (NCT05790876)
- Testing
- SSO2 therapy
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Grenoble
Septic Shock
Microcirculation Recruitment Using Albumin 20% and Terlipressin in Septic Patients
The aim of this study is to evaluate the effect of combining HSA 20% and terlipressin on the microcirculation in patients with septic shock using the following;- Microcirculation recruitment by Cytocam-IDF.
- Trial name
- NCT05080543
- Testing
- Albumin 20% and terlipressin
- Volunteers
- 36 people
- Sponsor
- Amany Mousa Salama Muhammed
Hypertension, Diabetes Mellitus
Population Research of Sublingual Microcirculation Data of Patients With Systemic Diseases
This is an observational clinical study, patients with systemic diseases will be enrolled according to the inclusion and exclusion criteria.
- Trial name
- NCT02940275
- Where
- Taiwan
- Volunteers
- 156 people
- Sponsor
- National Taiwan University Hospital
Metabolic Syndrome
NWT03 and Arterial Stiffness
Rationale: Subjects with the metabolic syndrome have an increased risk of developing cardiovascular disease and a twofold risk of developing hypertension.
- Trial name
- NCT02561663
- Testing
- NWT-03, an egg-white protein hydrolysate
- Where
- Netherlands
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Newtricious R&D BV
Acute Respiratory Distress Syndrome
Assessment of Microcirculation Alteration With Both Sublingual Microcirculation and Near-infrared Spectroscopy on ARDS
Microcirculatory alterations are frequently observed in critically ill and severe sepsis patients characterized by a decrease in capillary density and an increase in heterogeneity of perfusion.
- Trial name
- NCT05180409
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chang Gung Memorial Hospital
French PNNS Guidelines in Vascular Function
Impact of Dietary Status on Vascular Function Before and After a Standardized Breakfast. An "Exposed/Unexposed" Study Embedded in the SUVIMAX2 Cohort
In France, primary cardiovascular and metabolic prevention is supported by the French National Program for Nutrition and Health (PNNS: Programme National Nutrition Santé).
- Trial name
- Nutri-MicroVas (NCT01579409)
- Testing
- PNNS guidelines
- Where
- France
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Hypertension
Safety and Efficacy of Valsartan vs Atenolol and Hydrochlorothiazide Combination on Blood Flow in Hypertensive Patients
This study evaluated the effect of valsartan on small vessel blood flow in patients with mild-to-moderate hypertension in direct comparison to atenolol and hydrochlorothiazide.
- Trial name
- NCT00396656
- Testing
- Atenolol, Hydrochlorothiazide (HCTZ)), Valsartan
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 30 people
- Sponsor
- Novartis
Chronic Kidney Disease, Vitamin D Deficiency
Vitamin D, Chronic Kidney Disease (CKD) and the Microcirculation
Overall research aims: This study will examine the effect of vitamin D supplementation on the function of the endothelium and microcirculation of patients with chronic kidney disease and vitamin D deficiency.
- Trial name
- NCT00882401
- Testing
- Ergocalciferol (Vitamin D)
- Where
- United Kingdom
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Barts & The London NHS Trust
Microcirculation
Microcirculation of Patients With Kidney Transplant
This study measures the sublingual microcirculation of patients with kidney transplant using MicroScan. The data will be compared with data of health volunteers and end stage renal disease patients on hemodialysis.
- Trial name
- NCT02874781
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
Mesenteric Ischemia
Microcirculation During Extracorporeal Circulation
Digestive tract is supposed to be the motor of multiple organ failure. In ICU patients, mesenteric ischemia appears even when macrocirculatory parameters are controlled especially in our experience in patients coming in ICU after…
- Trial name
- CITRON4 (NCT01389947)
- Where
- France
- Volunteers
- 66 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Vasodilatation, Oral Soft Tissue Conditions
Endothelium Dependent and Non-dependent Vasodilatation in Human Gingiva
The aim of this study is to compare the endothelim-dependent and non-dependent vasodilatation between genders in the human gingiva.
- Trial name
- NCT04918563
- Testing
- Nitroglycerin, Acetylcholine
- Where
- Hungary
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Complication of Hemodialysis
Microcirculation During Haemodialysis
SDF is validated by measuring changes in microcirculation in sepsis patients with MOF (Boerma studies). SDF is validated by measuring changes in microcirculation in stable chronic hemodialysis patients (NDT 2009 Bemelmans).
- Trial name
- NCT01396980
- Where
- Netherlands
- Volunteers
- 8 people
- Sponsor
- Frisius Medisch Centrum
Sepsis and Septic Shock
Circulating Free Hemoglobin and Microcirculation After Administration of Paracetamol in Febrile Septic Patient
The aim of this study is to evaluate the effect of Acetaminophen on the main parameters of microcirculation, on the plasmatic levels of free hemoglobin/oxidative stress markers and on the expression of PD1/Pd-L1, in pyrexial…
- Trial name
- NCT02750163
- Testing
- paracetamol
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Università Politecnica delle Marche