Clinical trials: Microbiome Analysis
Autoimmune Gastritis
Clinical Characteristics, Lifestyle and Multi-omics Analysis in Autoimmune Gastritis
This research will be conducted nationwide in patients with autoimmune gastritis, focusing on their clinical characteristics, possible risk factors, and multi-omics analysis.
- Trial name
- NCT05820607
- Testing
- Microbiome, metabolome, transcriptome, genome
- Where
- China
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Periodontal Disease, Periodontitis
Antibiotic Resistance Genes in Periodontitis
Antimicrobial resistance (AMR) is a major global public health concern, and the oral microbiome may serve as an important reservoir of antibiotic resistance genes (ARGs).
- Conditions
- Periodontal Disease, Periodontitis, Antibiotic Resistance Genes
- Trial name
- NCT07887204
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Repeated Implantation Failure, Normal Fertile
Uterine Microbiome in Women with Repeated Implantation Failure and Normal Fertile Women
Characterization of the uterine microbiome in women with repeated implantation failure as well as in normal fertile women.
- Trial name
- NCT03405883
- Testing
- Vaginal swab + endometrial biopsy
- Where
- Belgium
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Colorectal Polyp, Inflammation
Impact of Dietary Intervention on Inflammation and Microbiome Composition Post-Colonoscopy
This study aims to investigate the impact of various healthy diets, specifically a modified plant-based Mediterranean diet, on the gut microbiome and overall well-being post-colonoscopy.
- Conditions
- Colorectal Polyp, Inflammation, Dietary Intervention, Microbiota
- Trial name
- NCT06603519
- Testing
- Modified Plant-Based Mediterranean Diet
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Healthy
Batch Fermentation and Microbiome Analysis
The correlation between diet and microbiota as well as the effect of microbiota on human health is well established. Studies have shown that people following specific diets have different microbiome profile compared to those…
- Trial name
- NCT06097130
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Major Depressive Disorder
Optimize and Predict Antidepressant Efficacy for Patient With MDD Using Multi-omics Analysis and AI-predictive Tool
OPADE is a non-profit, observational, multicenter, open-label study aimed at defining personalized treatment for Major Depressive Disorder (MDD).
- Trial name
- OPADE (NCT06550037)
- Where
- Italy
- Volunteers
- 350 people
- Sponsor
- Alessio Fasano
Plant-based Milk, Gastrointestinal Microbiome
Study the Effect of Plant-based Beverage Consumption on the Gut Microbiome in Healthy Adults
The goal of this intervention study is to analyse the microbiota composition after the plant-based beverage consumption. The main questions are to evaluate if the plant-based beverage can have a beneficial effect on the gut…
- Trial name
- NCT07730229
- Testing
- plant-based beverage
- Where
- Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lund University
Microbial Colonization, Gut Microbiota
Diet Supplementation With Prebiotics to Improve Gut Health in Egyptian Children
The study described herein seeks to assess the extent to which diet supplementation of young Egyptian children, one of the most vulnerable groups to the risk of diarrhea, with prebiotic fiber can improve their gut health.
- Trial name
- NCT06561724
- Testing
- Biscuits maltodextrin, Biscuits includes prebiotics tartoufa inulin, Biscuits includes prebiotics chicory inulin
- Where
- Egypt
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- National Research Centre, Egypt
Age-Related Macular Degeneration
Analysis of the Intestinal Microbiome in Patients With Wet Age-related Macular Degeneration
Analysis of the Intestinal Microbiome in Patients With Wet Age-related Macular Degeneration
- Trial name
- NCT05757674
- Testing
- Sample examination
- Where
- 2 sites in Greece
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Ioannina
Gastric Intestinal Metaplasia, Gastric Cancer
Microbiome Analysis in Gastric Intestinal Metaplasia and in Gastric Cancer and Subtypes Correlation
The aim of the study will be to analyze the microbiome in the blood and stomach in patients with intestinal metaplasia (IM) and / or gastric cancer (GC).
- Conditions
- Gastric Intestinal Metaplasia, Gastric Cancer, Microbiome
- Trial name
- NCT04365946
- Testing
- Gastroscopy
- Where
- Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ioannina
Microbial Colonization, Microbial Superinvasion
Metagenomic Analysis of Gut Microbiome in Preterm
This is single center study. The investigators will try to know that relationships between intestinal microbiome and mortality in preterm infants and what relationships is between intestinal microbiome in preterm infants and…
- Conditions
- Microbial Colonization, Microbial Superinvasion, Microbial Substitution, Newborn Morbidity
- Trial name
- MAGMP (NCT03235635)
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Wonju Severance Christian Hospital
Dry Eyes
Ocular Surface Dry Eye Microbiome
The investigators seek to characterize the identity of all microorganisms residing on the eye's surface (conjunctiva) in healthy eyes and those with dry eye syndrome, using a combination of analyses.
- Trial name
- NCT02306668
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Washington
Cardiovascular Disease (CVD), Cardiovascular Risk Factor
Women's Advanced Risk-assessment in Manitoba
The main objective of this study is to test the ability of novel cardiovascular disease (CVD) prognostic tools to identify women at risk for future CVD. We plan to establish a cardiovascular health screening program at the St.
- Conditions
- Cardiovascular Disease (CVD), Cardiovascular Risk Factor, Vascular Stiffness
- Trial name
- WARM (NCT03938155)
- Where
- Canada
- Volunteers
- 1,000 people
- Sponsor
- St. Boniface Hospital
Rosacea
Analysis of the Microbiome in Rosacea
The skin and gut microbiome of rosacea patients differs from individuals without rosacea and that the microbiome suffers from unique derangements in rosacea patients following antibiotic therapy.
- Trial name
- NCT04108897
- Testing
- Doxycycline, Ivermectin Topical
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Irritable Bowel Syndrome, Irritable Bowel Syndrome With Diarrhea
Personalized Dietary Intervention Based on Microbiome Analysis vs FODMAP Diet for Irritable Bowel Syndrome
irritable bowel syndrome (IBS) is a well-known risk factor for diseases of the anal region (hemorrhoids, anal fissures, etc.) and large intestine (colon cancer, diverticular disease).
- Conditions
- Irritable Bowel Syndrome, Irritable Bowel Syndrome With Diarrhea, Irritable Bowel Syndrome With Constipation, Irritable Bowel Syndrome Mixed
- Trial name
- NCT05646186
- Testing
- Personalized dietary intervention based on microbiome analysis, Low-FODMAP diet
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istanbul Medipol University Hospital
Microbiome Analysis, Drug Abuse in Pregnancy
Alcohol and Cannabis Use Among Pregnant Slovenian Women
The aim of the study is to determine the prevalence of alcohol and drug use among Slovenian pregnant women. Alcohol and drug use during pregnancy has significant effects on the foetus and has short- and long-term health…
- Conditions
- Microbiome Analysis, Drug Abuse in Pregnancy, Alcohol Abuse in Pregnancy, Health Behavior, Risky
- Trial name
- NCT07456579
- Where
- Slovenia
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Microbiota, Eczema
Infant Restore: Efficacy of Microbiome Analysis and Education
The goal of this clinical trial is to learn if a microbiome analysis, education, and recommendation program can improve gut health, reduce future health risks, and empower parents in their children's health in infants aged 0-3…
- Conditions
- Microbiota, Eczema, Microbiome, Gut Microbiome
- Trial name
- NCT06424691
- Testing
- Tailored Recommendations, Consult Call, Email Series
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Seeding Inc
Gastrointestinal Microbiome
A Cohort Analysis Study of Intestinal Flora in Infants
The purpose of this study is to investigate the influence factors of gastrointestinal microbiome in infants.
- Trial name
- NCT03396198
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mizu Jiang
Acne, Atopic Dermatitis
Sebum Metabolomics and Lipidomics for Clinical Applications
This study aims to develop a standardized workflow for sebum sampling and metabolomics/lipidomics analysis using Sebutape. A total of 200 participants will be recruited, including healthy individuals, patients with skin diseases…
- Conditions
- Acne, Atopic Dermatitis, Seborrheic Dermatitis, Psoriasis
- Trial name
- NCT07549828
- Testing
- Sebutape sampling, Bacitracin/Polymyxin B/Neomycin ointment (Yentuogin ointment)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Abdominal Surgery
Analysis of the Composition of the Intestinal Microbiota in Patients Post-intestinal Anastomosis
Recent research suggests a significant link between gut microbiota and anastomotic leakage (AL) in colorectal surgery. Patients who develop AL have a higher abundance of bacteria from the Lachnospiraceae family and lower…
- Trial name
- MIDESIN (NCT07416760)
- Testing
- Not applicable- observational study
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz