Clinical trials: Methamphetamine Dependence
Opioid Use Disorder, Medication Adherence
MHealth Incentivized Adherence Plus Patient Navigation
Polysubstance use involving opioids and methamphetamine is emerging as a new public health crisis. Patients with opioids and methamphetamine use often experience serious medical complications requiring hospitalization, which…
- Conditions
- Opioid Use Disorder, Medication Adherence, Polysubstance Drug Use (Indiscriminate Drug Use), Methamphetamine-dependence
- Trial name
- MIAPP (NCT06027814)
- Testing
- Patient Navigation and mHealth (PN+mHealth)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Washington
Substance-Related Disorders
Methamphetamine Abuse Treatment in Patients With AIDS - 1
The purpose of this study is to evaluate the efficacy of desipramine, sertraline, and placebo on methamphetamine dependent gay men with AIDS.
- Trial name
- NCT00000321
- Testing
- Desipramine
- Where
- United States
- Sponsor
- National Institute on Drug Abuse (NIDA)
Substance Use Disorders, Opioid Use Disorder
Enhanced Digital-Chemosensory-Based Olfactory Training for Remote Management of Substance Use Disorders
The overarching goal of this study phase, Phase II component is to implement Enhanced Digital-Chemosensory-Based Olfactory Training for Remote Management of Substance Use Disorders (EDITOR) device in substance use disorder (SUD)…
- Conditions
- Substance Use Disorders, Opioid Use Disorder, Alcohol Use Disorder, Cocaine Use Disorder
- Trial name
- EDITOR (NCT06434818)
- Testing
- EDITOR (CBOT with olfactory stimulants, OFC tasks & remote monitoring of treatment compliance), CBOT with olfactory stimulants & OFC tasks
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- Evon Medics LLC
Methamphetamine Dependence, Substance Abuse
Rivastigmine as a Treatment for Methamphetamine Dependence
To study the effects of treatment with rivastigmine on craving produced by experimental administration of methamphetamine.
- Conditions
- Methamphetamine Dependence, Substance Abuse, Methamphetamine Abuse
- Trial name
- NCT01073319
- Testing
- Rivastigmine
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Baylor College of Medicine
Amphetamine Abuse, Amphetamine Dependence
Combination of Psychosocial Intervention and Slow Prosecutions for the Treatment of Methamphetamine Abuse/Dependence
The hospital where this study will be conducted is responsible for the one-year contingency management treatment for methamphetamine drug offenders referred from the Yunlin District Prosecutors Office.
- Conditions
- Amphetamine Abuse, Amphetamine Dependence, Methamphetamine Abuse, Methamphetamine Dependence
- Trial name
- NCT01273701
- Testing
- Psychosocial intervention, Telephone reminding
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Methamphetamine Dependence
Safety and Tolerability of Modafinil for Methamphetamine Dependence
This 7 week, open-label pilot clinical trial will examine the safety and tolerability of modafinil up to 400mg/day as a potential treatment to reduce methamphetamine use in methamphetamine-dependent volunteers.
- Trial name
- NCT00569374
- Testing
- Modafinil
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Methamphetamine or Cocaine Dependence
Doxazosin for Psychostimulant Dependence
Psychostimulant dependence is a major public health problem and no medications have been shown to be very effective in treating this disorder.
- Trial name
- NCT01371851
- Testing
- Doxazosin extended release
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Arkansas
Methamphetamine
Effectiveness of Bupropion Combined With Behavioral Therapy for Treating Methamphetamine Dependence - 2
Methamphetamine is an addictive stimulant drug that strongly activates certain parts of the brain. The purpose of this study is to determine the effectiveness of bupropion in combination with behavioral therapy for the treatment…
- Trial name
- NCT00135785
- Testing
- Bupropion
- Where
- 2 sites in United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Methamphetamine-dependence, Postpartum Abstinence
PRevention Of Methamphetamine Use Among Postpartum Women Trial (PROMPT)
The PRevention Of Methamphetamine Use among Postpartum Women Trial (PROMPT) is randomized controlled trial of postpartum individuals with methamphetamine use disorder to 12 weeks of 200 mg oral micronized progesterone twice daily…
- Trial name
- NCT05128071
- Testing
- Progesterone
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Utah
Substance-Related Disorders
Flupenthixol Decanoate in Methamphetamine Smoking - 1
The purpose of this study is to evaluate the safety and efficacy of flupenthixol decanoate for treatment of methamphetamine dependence.
- Trial name
- NCT00000241
- Testing
- Flupenthixol
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Methamphetamine Abuse, Methamphetamine-dependence
Feasibility of Long-term, High-dose Stimulant for Methamphetamine Use Disorder
Methamphetamine use disorder (MUD) is becoming an increasing public health concern in Canada. While the evidence on the efficacy and safety of prescription psychostimulants for the treatment of MUD is promising, the knowledge on…
- Conditions
- Methamphetamine Abuse, Methamphetamine-dependence, Addiction, Substance Abuse
- Trial name
- NCT06788587
- Testing
- LDX-01 plus TAU
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Methamphetamine Dependence
Open-Label Disulfiram for Methamphetamine Dependence
This 8 week, open-label pilot clinical trial will examine the safety and tolerability of disulfiram at 250 mg/day in up to fifteen methamphetamine dependent individuals.
- Trial name
- NCT00731133
- Testing
- Disulfiram
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Arkansas
Methamphetamine Dependence
Risk and Protective Factors for Rural Methamphetamine Dependence
The primary goal of this study is to identify factors which may put a person that has used methamphetamine at greater risk for mental and physical health problems and social problems and factors that may lessen the risk for these…
- Trial name
- NCT00882037
- Where
- 2 sites in United States
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Methamphetamine Dependence
Tolerability and Safety of 30, 45, and 60 mg of Sublingual Lobeline. - 1
The purpose of this study is to assess safety and pharmacokinetics of sublingual lobeline in healthy normal volunteers.
- Trial name
- NCT00519259
- Testing
- Lobeline
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Amphetamine-Related Disorders
Ondansetron for the Treatment of Methamphetamine Dependence - 1
The purpose of this study is to assess ondansetron for the treatment of methamphetamine dependence.
- Trial name
- NCT00040053
- Testing
- Ondansetron
- Where
- 6 sites in United States
- Volunteers
- 154 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Substance Abuse, HIV Infections
Aripiprazole Treatment for Methamphetamine Dependence Among High-risk Individuals
Studies demonstrate that methamphetamine (meth) use is associated with high-risk sexual behavior among men who have sex with men (MSM), putting meth-using MSM at extraordinarily high risk for transmitting or acquiring HIV.
- Trial name
- NCT00497055
- Testing
- Aripiprazole
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- San Francisco Department of Public Health
Methamphetamine-dependence
Transcranial Magnetic Stimulation for Treatment of Methamphetamine Dependence
Repetitive transcranial magnetic stimulation (rTMS) was used to treat methamphetamine (MA) addiction in previous studies, while the evidence-based protocols still required.
- Trial name
- NCT03827785
- Testing
- rTMS treatment group
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Methamphetamine Dependence
A Randomized, Placebo-Controlled Trial of Modafinil for Methamphetamine Dependence
The proposed study will establish the safety and efficacy of modafinil in the treatment of methamphetamine dependence, as well as assess the affects of modafinil on cognitive function in methamphetamine users and on…
- Trial name
- NCT01354470
- Testing
- Modafinil
- Where
- 2 sites in United States
- Volunteers
- 72 people
- Sponsor
- California Pacific Medical Center Research Institute
Amphetamine-Related Disorders
Mirtazapine for the Treatment of Methamphetamine Dependence Among MSM (M2.0)
The investigators recently conducted a double-blind, randomized controlled trial (n=60) of limited duration (12 weeks), and found that compared with placebo, oral mirtazapine, an FDA-approved antidepressant, significantly reduced…
- Trial name
- NCT01888835
- Testing
- Mirtazapine
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Phillip Coffin, MD, MIA
Methamphetamine Dependence, Substance Abuse
Varenicline-Methamphetamine Interaction Study (2008)
The primary aim of the study is to determine the safety and tolerability of treatment with Varenicline in methamphetamine-dependent volunteers.
- Conditions
- Methamphetamine Dependence, Substance Abuse, Methamphetamine Abuse
- Trial name
- NCT00733967
- Testing
- Varenicline
- Sponsor
- Baylor College of Medicine