Clinical trials: Methamphetamine Dependence
Methamphetamine Use Disorder
TACS Intervention for Methamphetamine Addiction
In 2021, nearly 296 million people worldwide used psychoactive substances, highlighting a significant need for effective interventions for disorders such as Methamphetamine Use Disorder (MUD).
- Trial name
- tACS for MUD (NCT06288997)
- Testing
- Active transcranial alternating current stimulation
- Where
- 5 sites in China
- Volunteers
- 70 people
- Sponsor
- Shanghai Mental Health Center
Methamphetamine Addiction
A Pilot Trial of Modafinil for Treatment of Methamphetamine Dependence
Patients treated for methamphetamine dependence have high rates of relapse, and no pharmacotherapy has yet been demonstrated to be efficacious.
- Trial name
- NCT00538655
- Testing
- modafinil
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- California Pacific Medical Center Research Institute
Methamphetamine-dependence, Methamphetamine Abuse
Multiple-Dose Study to Evaluate the Safety and Efficacy of IXT-m200
This Phase 2 study will evaluate the safety and efficacy of monthly intravenous doses of IXT-m200 in treatment-seeking individuals with methamphetamine (METH) use disorder.
- Trial name
- OUTLAST (NCT05034874)
- Testing
- IXT-m200
- Where
- 9 sites in United States
- Volunteers
- 61 people
- Sponsor
- InterveXion Therapeutics, LLC
Methamphetamine Dependence
N-Acetyl Cysteine Plus Naltrexone in Methamphetamine Dependence
The goal of the proposed study is to evaluate the efficacy and safety of N-Acetyl Cysteine (NAC) in combination with naltrexone in methamphetamine dependence.
- Trial name
- NCT00332605
- Testing
- Naltrexone plus N-Acetyl Cysteine
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Chicago
Methamphetamine Dependence
Citicoline Treatment of Methamphetamine Dependence
The purpose of the study is to determine if citicoline (a nutritional supplement) is effective in helping people reduce their dependence on methamphetamine.
- Trial name
- NCT00950352
- Testing
- Citicoline
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Perry Renshaw
Stimulant Use Disorder
Smartphone Services for Stimulant Use Disorder
This study is testing two approaches to treating Stimulant Use Disorder, or problems with cocaine, crack, methamphetamine, etc. Stimulant Use Disorder is a national epidemic in the U.S.
- Trial name
- NCT07092059
- Testing
- Smartphone digital therapeutic system
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- DynamiCare Health
Methamphetamine Abuse, Methamphetamine-dependence
ACT for Methamphetamine Use Disorder in Women and Gender Non-Conforming Individuals
This study aims to assess the feasibility, acceptability and preliminary effectiveness of Acceptance Commitment Therapy, in conjunction with motivation enhancement, and the use of the ChillTime App, in reducing methamphetamine…
- Trial name
- NCT05334914
- Testing
- Acceptance Commitment Therapy
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Centre for Addiction and Mental Health
Methamphetamine Dependence, Methamphetamine Abuse
Buspirone as a Candidate Medication for Methamphetamine Abuse
Methamphetamine use disorders are an unrelenting public health concern. Intensive research efforts have yielded behavioral interventions that reduce methamphetamine use, however, these interventions are not universally effective…
- Trial name
- NCT01843205
- Testing
- Methamphetamine
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Kentucky
Methamphetamine Dependence
Clinical Efficacy of Atomoxetine for Methamphetamine Dependence
The purpose of this study is to examine the ability of atomoxetine compared to placebo to increase time to relapse in methamphetamine dependent volunteers.
- Trial name
- ATM (NCT01557569)
- Testing
- Atomoxetine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Arkansas
Methamphetamine Abuse, Methamphetamine Dependence
NAC as a Potential Treatment for Methamphetamine Dependence
The purpose of this study is to determine the effects of treatment with NAC, compared to treatment with placebo, on cue- and methamphetamine (MA)-induced craving and MA subjective effects in non-treatment-seeking MA-dependent…
- Conditions
- Methamphetamine Abuse, Methamphetamine Dependence, Substance Abuse
- Trial name
- NCT01063205
- Testing
- N-acetylcysteine
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Baylor College of Medicine
Methamphetamine Dependence
Efficacy and Safety of CDP-choline in Patients With Methamphetamine Dependence
The purpose of the study is to determine if cytidine 5'diphosphocholine (CDP-choline, a naturally occurring chemical in your body) has efficacy in reducing the methamphetamine craving of the subjects with methamphetamine…
- Trial name
- NCT01007539
- Testing
- CDP-choline
- Where
- 2 sites in South Korea
- Volunteers
- 31 people
- Sponsor
- Seoul National University Hospital
Methamphetamine Dependence
An Study of Aripiprazole in the Treatment of Methamphetamine Dependence
Methamphetamine substance use is common worldwide. No approved pharmacologic treatments for methamphetamine dependence exist. Aripiprazole are Second generation antipsychotics，but have different pharmacological effects of…
- Trial name
- NCT01813656
- Testing
- Aripiprazole
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Wei Hao
Methamphetamine Dependence
Methylphenidate to Treat Methamphetamine Dependence
This 4-year study will investigate the effectiveness of methylphenidate for initiating and sustaining abstinence in methamphetamine dependent individuals.
- Trial name
- MPH (NCT01044238)
- Testing
- methylphenidate
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of California, Los Angeles
Opioid-use Disorder, Cocaine Use Disorder
Encouraging Abstinence Behavior in a Drug Epidemic: Optimizing Dynamic Incentives
Combatting the rise of the opioid epidemic is a central challenge of U.S. health care policy. A promising approach for improving welfare and decreasing medical costs of people with substance abuse disorders is offering incentive…
- Conditions
- Opioid-use Disorder, Cocaine Use Disorder, Opioid Use, Cocaine Use
- Trial name
- NCT04927143
- Testing
- App-Based Contingency Management
- Where
- 2 sites in United States
- Volunteers
- 206 people
- Sponsor
- Wake Forest University Health Sciences
Methamphetamine Dependence
Transcranial Magnetic Stimulation Used to Both Measure Cortical Excitability and Explore Methamphetamine Cue Craving
Specific Primary Aims include: Aim # 1. The investigators explore the feasibility of using the TMS to investigate the cortical excitability and to inhibit meth cue craving in meth dependent population.
- Trial name
- NCT01685463
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Stimulant Dependence
An Eval of Neurocognitive Function, Oxidative Damage, and Their Association With Outcomes in METH and Cocaine Abusers.
The purpose of this study is to determine whether performance on neurocognitive measures predicts treatment outcomes in individuals with substance abuse disorders.
- Trial name
- NCT00628927
- Where
- 6 sites in United States
- Volunteers
- 217 people
- Sponsor
- University of Cincinnati
Treatment Methamphetamine Addiction
Deep Brain Stimulation of Nucleus Accumbens for Methamphetamine Addiction
The main objective of this study is to assess the efficacy of bilateral deep brain stimulation (DBS) of the Nucleus Accumbens(NAc) as a novel treatment in severe methamphetamine addiction.
- Trial name
- NCT03347474
- Testing
- Bilateral surgical implantation of DBS system to NAc
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Ruijin Hospital
Substance Dependence, Amphetamine Dependence
A Dose Ranging Study of Modafinil for Methamphetamine Dependence
Patients treated for methamphetamine dependence have high rates of relapse, and no pharmacotherapy has yet been demonstrated to be efficacious.
- Trial name
- NCT00630097
- Testing
- modafinil
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- California Pacific Medical Center Research Institute
Stress Physiology, Stress Reaction
The Human Stress Response in a Simulated ED Setting
Stress is important for health. As emergency departments (EDs) are often stressful places, a better understanding of the human stress response is important for understanding how and why patients respond as they do when they come…
- Conditions
- Stress Physiology, Stress Reaction, Substance Use Disorders, Methamphetamine-dependence
- Trial name
- NCT04317482
- Testing
- Standard social stress task, Stressful experience in the ED
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Methamphetamine Dependence
Pilot Study of Entacapone for Methamphetamine Abuse
Addiction to methamphetamine is a serious health problem. There are no medications that a doctor can give someone to help them stop using methamphetamine.
- Trial name
- NCT02058966
- Testing
- Entacapone, Methamphetamine
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University