Clinical trials: Methamphetamine Dependence
Substance-Related Disorders
A Behavioral Trial for the Treatment of Methamphetamine Dependence. - 1
The purpose of this study is to examine behavioral treatment for methamphetamine dependence.
- Trial name
- NCT00033124
- Testing
- Behavior Therapy
- Where
- 5 sites in United States
- Volunteers
- 50 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Amphetamine-Related Disorders
Bupropion for the Treatment of Methamphetamine Dependence - 1
The purpose of this study is to assess the efficacy and safety of bupropion in reducing methamphetamine use in subjects with methamphetamine dependence
- Trial name
- NCT00069251
- Testing
- Bupropion
- Where
- 5 sites in United States
- Volunteers
- 150 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Methamphetamine Abuse, Methamphetamine Dependence
Targeting GABA and Opioid Systems for a Pharmacotherapy for Methamphetamine Abuse
The research proposed in this application will determine the initial efficacy, safety and tolerability of a novel drug combination, oxazepam (Serax®) and naltrexone (Revia®), as a pharmacotherapy for methamphetamine (Desoxyn®)…
- Trial name
- NCT01967381
- Testing
- Methamphetamine (Desoxyn®)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Kentucky
Methamphetamine Dependence
Effects of Modafinil in Methamphetamine Dependence
Methamphetamine dependence is a serious public health problem with no pharmacologic treatments currently available. Relapse rates are high in this population.
- Trial name
- NCT00751023
- Testing
- Modafinil
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Medical University of South Carolina
Methamphetamine Dependence
Intensive Motivational Interviewing for Methamphetamine Dependence
A Stage 2 randomized clinical trial (RCT) to test the efficacy of a 9-session model of motivational interviewing (MI) for methamphetamine (MA) dependence.
- Trial name
- NCT01071356
- Testing
- Intensive MI, Single session MI
- Where
- United States
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Public Health Institute, California
Methamphetamine-dependence
Pilot Study of the Effect of Ibudilast on Neuroinflammation in Methamphetamine Users
Addiction to methamphetamine is a serious health problem in the United States. Right now, there are no medications that a doctor can give someone to help them stop using methamphetamine.
- Trial name
- Ibudilast (NCT03341078)
- Testing
- Ibudilast
- Where
- United States
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Methamphetamine-dependence
Effects of Genotype on Resting State Connectivity During Methamphetamine Administration
Addiction to methamphetamine (MA) is a serious health problem in the United States. Right now, there are no medically approved treatments for MA dependence.
- Trial name
- MATAAR (NCT03973489)
- Testing
- Magnetic resonance imaging (MRI), Methamphetamine Hydrochloride Tablets
- Where
- 2 sites in United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Substance Abuse, HIV Infections
Acceptability of Pharmacologic Treatment for Methamphetamine Dependence Among MSM
Studies demonstrate that methamphetamine (meth) use is associated with high-risk sexual behavior among MSM, putting meth-using MSM at extraordinarily high risk for transmitting or acquiring HIV.
- Trial name
- NCT00318409
- Testing
- Bupropion
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- San Francisco Department of Public Health
Methamphetamine Dependence
Ph1 Lobeline Interaction Study - 1
The purpose of this study is to determine if there are significant cardiovascular or other interactions between sublingual lobeline and intravenous methamphetamine.
- Trial name
- NCT00439504
- Testing
- Lobeline
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Crystal Methamphetamine Abuse, Crystal Methamphetamine Dependence
Behavioral Activation and HIV Risk Reduction for Men Who Have Sex With Men With Crystal Meth Abuse
The purpose of this study is to research a new behavioral treatment to reduce sexual risk-taking in men who have sex with men (MSM) who abuse crystal methamphetamine (crystal meth), and are at risk for HIV acquisition.
- Trial name
- NCT01255280
- Testing
- Behavioral Activation Therapy and Risk Reduction Counseling (BAT-RR), Information, Motivation, Behavioral skills change approach to sexual risk reduction
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Massachusetts General Hospital
Amphetamine Dependence
Trial of Modafinil for Methamphetamine Dependence
The study aims to evaluate the safety and efficacy of modafinil (200 mg/day) over 10 weeks plus a tailored cognitive behavioural therapy program in the treatment of methamphetamine dependence.
- Trial name
- NCT00123370
- Testing
- Modafinil
- Where
- 2 sites in Australia
- Volunteers
- 87 people
- Sponsor
- The University of New South Wales
Methamphetamine-dependence
Glutide for Ending Methamphetamine
GEM is a two-phase study to evaluate the use of semaglutide (Wegovy) for the treatment of methamphetamine use disorder (MeUD). The first phase is a pilot study, which will be an open-label, single-arm pilot study of 25…
- Trial name
- GEM (NCT07204249)
- Testing
- Semaglutide
- Where
- United States
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- San Francisco Department of Public Health
Substance Abuse
Positive Effects of Laser Acupuncture in Methamphetamine Users Undergoing Group Cognitive Behavioral Therapy: A Pilot Study
Methamphetamine (MA) addiction has become a crucial public health issue due to its adverse effects. Acupuncture has been used for drug detoxification for many years. However, some disadvantages are not be suitable for MA users.
- Trial name
- NCT04789772
- Testing
- Laser acupuncture
- Where
- 2 sites in Taiwan
- Volunteers
- 15 people
- Sponsor
- Chang Gung Memorial Hospital
Methamphetamine-dependence, Transcranial Direct Current Stimulation
Transcranial Direct Current Stimulation (tDCS) Combined With Computerized Cognitive Addiction Therapy(CCAT) and, Electronic Follow-up for Methamphetamine(MA) Dependent Patients
Transcranial direct current stimulation (tDCS) combined with computerized cognitive addiction therapy(CCAT) for methamphetamine(MA) dependent patients in voluntary drug rehabilitation center.
- Conditions
- Methamphetamine-dependence, Transcranial Direct Current Stimulation, Computerized Cognitive AddictionTherapy, Electronic Health Records
- Trial name
- NCT04139148
- Testing
- Ture Transcranial Direct Current Stimulation (tDCS)
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shanghai Mental Health Center
Methamphetamine Dependence
Comparison of Methamphetamine-Dependent and Healthy Volunteers Using a Web-Enabled Cognitive Neuropsychological Evaluation System
The purpose of this study is to develop the technology infrastructure for a mobile Web-based cognitive and neuropsychological assessment of substance abusers, and to perform a pilot trial using neurocognitive tasks designed to…
- Trial name
- 5I (NCT01919437)
- Testing
- Web-Enabled Cognitive Neuropsychological Evaluation System
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- California Pacific Medical Center Research Institute
Methamphetamine Dependence, Substance Abuse
RTI-336 as a Treatment for Methamphetamine Dependence
The purpose of this study is to evaluate the safety and efficacy of RTI-336 as a treatment for methamphetamine (METH) dependence in non-treatment-seeking METH-dependent volunteers.
- Conditions
- Methamphetamine Dependence, Substance Abuse, Methamphetamine Abuse
- Trial name
- NCT01601717
- Testing
- RTI-336
- Sponsor
- Baylor College of Medicine
Methamphetamine Addiction
A Pilot Trial of Dextroamphetamine for Methamphetamine Dependence
The purpose of this study is to assess the safety and effectiveness dextroamphetamine to help methamphetamine users quit or cut down on their use. The study lasts for 9 weeks.
- Trial name
- 1D (NCT00630682)
- Testing
- Dextroamphetamine
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- California Pacific Medical Center Research Institute
Amphetamine-Related Disorders
Extended-Release Naltrexone to Treat Methamphetamine Dependence in Men Who Have Sex With Men (MSM)
Extended-release naltrexone (XR-NTX, VIVITROL) is an FDA-approved medication with efficacy in treating alcohol dependence and prevention of relapse to opioid dependence.
- Trial name
- TREX (NCT01449565)
- Testing
- Naltrexone
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- San Francisco Department of Public Health
HIV-1-infection, Methamphetamine-dependence
Effect of Methamphetamine on Residual Latent HIV Disease Study
The most commonly used illicit stimulant in HIV-infected individuals is methamphetamine (MA). Prior studies demonstrate strong evidence that MA promotes increased HIV transcription as well as immune dysregulation.
- Trial name
- EMRLHD (NCT03825536)
- Testing
- Oral Methamphetamine
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of California, San Francisco
Methamphetamine-dependence
Repetitive dTMS Intervention for Methamphetamine Addiction
A growing body of evidence suggests a wide range of brain areas including medial prefrontal cortex (mPFC), dorsolateral prefrontal cortex (DLPFC) and other subcortical regions, such as anterior cingulate cortex (ACC) are critical…
- Trial name
- NCT04202926
- Testing
- real coil
- Where
- China
- Volunteers
- 23 people
- Sponsor
- Shanghai Mental Health Center