Clinical trials: Methamphetamine Abuse
Substance-Related Disorders
Rivastigmine For Methamphetamine Dependent Individuals
Methamphetamine abuse has been steadily increasing over the past decade. Rivastigmine is a medication that may be helpful in treating methamphetamine dependence.
- Trial name
- NCT00158210
- Testing
- Rivastigmine
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Methamphetamine Dependence, Substance Abuse
RTI-336 as a Treatment for Methamphetamine Dependence
The purpose of this study is to evaluate the safety and efficacy of RTI-336 as a treatment for methamphetamine (METH) dependence in non-treatment-seeking METH-dependent volunteers.
- Conditions
- Methamphetamine Dependence, Substance Abuse, Methamphetamine Abuse
- Trial name
- NCT01601717
- Testing
- RTI-336
- Sponsor
- Baylor College of Medicine
Methamphetamine Addiction
A Pilot Trial of Dextroamphetamine for Methamphetamine Dependence
The purpose of this study is to assess the safety and effectiveness dextroamphetamine to help methamphetamine users quit or cut down on their use. The study lasts for 9 weeks.
- Trial name
- 1D (NCT00630682)
- Testing
- Dextroamphetamine
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- California Pacific Medical Center Research Institute
Opioid Use Disorder, Methamphetamine Abuse
Contingency Management for Drug Use: Does Age Matter?
The OVERALL AIM is to assess whether app-based incentives are effective for older adults and to quantify the associations between age and both the efficacy and take-up of app-based incentives.
- Conditions
- Opioid Use Disorder, Methamphetamine Abuse, Cocaine Use Disorder
- Trial name
- NCT05521854
- Testing
- DynamiCare app (app-based contingency management)
- Where
- 2 sites in United States
- Volunteers
- 62 people
- Sponsor
- Wake Forest University Health Sciences
Substance Use Disorders, Methamphetamine Abuse
A Clinical Study to Evaluate the Safety of CS-1103 in Healthy Participants
The purpose of this Phase 1a study is to evaluate safety, tolerability, and pharmacokinetics (PK) of single, ascending doses of CS-1103, administered by intravenous (IV) infusion in healthy participants.
- Conditions
- Substance Use Disorders, Methamphetamine Abuse, Methamphetamine Intoxication
- Trial name
- NCT06316973
- Testing
- CS-1103, Sterile Saline
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Clear Scientific, Inc.
Methamphetamine Abuse, HIV/AIDS
FASTLANE II: Reducing Sex, Drug, and Mental Health Risk
The study uses a repeated measures, single group pretest-posttest design methodology to examine the feasibility, acceptability, and preliminary effectiveness of the FASTLANE II intervention aimed at decreasing risky sex behaviors…
- Conditions
- Methamphetamine Abuse, HIV/AIDS, Depression, Sex, Unsafe
- Trial name
- FLII (NCT04109014)
- Testing
- FASTLANE II
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Substance Use Disorders, Methamphetamine Abuse
Pharmacogenetics of Naltrexone for Stimulant Abuse
This investigation will be the first study assessing genetic modulation of naltrexone's NTX effects upon the abuse liability of a stimulant drug (methamphetamine).
- Trial name
- NCT03226223
- Testing
- Intranasal Methamphetamine
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- New York State Psychiatric Institute
Drug Abuse
Stimulant Abuser Groups to Engage in 12-Step
The purpose of this study is to determine whether a combined group and individual 12-Step facilitative (TSF) intervention, Stimulant Abuser Groups to Engage in 12 -Step (STAGE-12), improves substance -related outcomes.
- Trial name
- STAGE-12 (NCT00573183)
- Testing
- STAGE-12, Treatment as Usual
- Where
- 10 sites in United States
- Volunteers
- 471 people
- Sponsor
- University of Washington
Methamphetamine Abuse
Exercise in Methamphetamine Use Disorder Upregulation and Neural Function
The purpose of this research study is to determine the effects of an exercise intervention and health-education program on brain dopamine receptors and on cognitive functions that have been linked to these receptors.
- Trial name
- NCT03709667
- Testing
- EX, CON
- Where
- United States
- Volunteers
- 113 people
- Sponsor
- University of California, Los Angeles
Methamphetamine-dependence, Methamphetamine Abuse
Multiple-Dose Study to Evaluate the Safety and Efficacy of IXT-m200
This Phase 2 study will evaluate the safety and efficacy of monthly intravenous doses of IXT-m200 in treatment-seeking individuals with methamphetamine (METH) use disorder.
- Trial name
- OUTLAST (NCT05034874)
- Testing
- IXT-m200
- Where
- 9 sites in United States
- Volunteers
- 61 people
- Sponsor
- InterveXion Therapeutics, LLC
Stimulant Use Disorder
Smartphone Services for Stimulant Use Disorder
This study is testing two approaches to treating Stimulant Use Disorder, or problems with cocaine, crack, methamphetamine, etc. Stimulant Use Disorder is a national epidemic in the U.S.
- Trial name
- NCT07092059
- Testing
- Smartphone digital therapeutic system
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- DynamiCare Health
Methamphetamine Abuse
tACS Treatment for Cognitive Impairments in Methamphetamine Addicts
1. To evaluate the cognitive function of methamphetamine Patients. 2. Investigate the pathological mechanism of methamphetamine patients from the aspects of EEG and biology; 3.
- Trial name
- NCT06292156
- Testing
- Theta treatment group
- Where
- China
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Beijing HuiLongGuan Hospital
Methamphetamine Abuse, Methamphetamine-dependence
ACT for Methamphetamine Use Disorder in Women and Gender Non-Conforming Individuals
This study aims to assess the feasibility, acceptability and preliminary effectiveness of Acceptance Commitment Therapy, in conjunction with motivation enhancement, and the use of the ChillTime App, in reducing methamphetamine…
- Trial name
- NCT05334914
- Testing
- Acceptance Commitment Therapy
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Centre for Addiction and Mental Health
Methamphetamine Induced Psychosis, Cannabis Use
Psychiatric Symptom Characteristics in Methamphetamine-Induced Psychosis With and Without Lifetime Cannabis Use
This prospective cohort study aims to investigate factors associated with psychiatric symptom severity in participants diagnosed with methamphetamine-induced psychotic disorder (MP) with and without lifetime cannabis use (LCU).
- Trial name
- NCT07459270
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Elazığ Mental Health and Diseases Hospital
Methamphetamine Dependence, Methamphetamine Abuse
Buspirone as a Candidate Medication for Methamphetamine Abuse
Methamphetamine use disorders are an unrelenting public health concern. Intensive research efforts have yielded behavioral interventions that reduce methamphetamine use, however, these interventions are not universally effective…
- Trial name
- NCT01843205
- Testing
- Methamphetamine
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Kentucky
Methamphetamine Abuse, Methamphetamine Dependence
NAC as a Potential Treatment for Methamphetamine Dependence
The purpose of this study is to determine the effects of treatment with NAC, compared to treatment with placebo, on cue- and methamphetamine (MA)-induced craving and MA subjective effects in non-treatment-seeking MA-dependent…
- Conditions
- Methamphetamine Abuse, Methamphetamine Dependence, Substance Abuse
- Trial name
- NCT01063205
- Testing
- N-acetylcysteine
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Baylor College of Medicine
Substance-Related Disorders, Dental Caries
A Comparative Feasibility Study to Assess the Prevalence and Severity of Dental Caries in Incarcerated People Who Abuse Methamphetamine
The prevalence and severity of dental caries in incarcerated people who abuse drugs are unknown but an inmate reporting to the dental clinic typically presents with myriad findings: oral signs of uncontrolled decay on the buccal…
- Trial name
- NCT01224002
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Opioid-use Disorder, Cocaine Use Disorder
Encouraging Abstinence Behavior in a Drug Epidemic: Optimizing Dynamic Incentives
Combatting the rise of the opioid epidemic is a central challenge of U.S. health care policy. A promising approach for improving welfare and decreasing medical costs of people with substance abuse disorders is offering incentive…
- Conditions
- Opioid-use Disorder, Cocaine Use Disorder, Opioid Use, Cocaine Use
- Trial name
- NCT04927143
- Testing
- App-Based Contingency Management
- Where
- 2 sites in United States
- Volunteers
- 206 people
- Sponsor
- Wake Forest University Health Sciences
Adolescent Methamphetamine Abuse
Pilot Trial of Bupropion Versus Placebo for Methamphetamine Abuse in Adolescents
Dr Keith Heinzerling, who is a doctor at UCLA, is doing a research study with Behavioral Health Services in the Lincoln Heights neighborhood of Los Angeles to find out if a medication called bupropion can help adolescents (age…
- Trial name
- NCT00994448
- Testing
- Bupropion SR 150mg tabs
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of California, Los Angeles
Methamphetamine Dependence
Pilot Study of Entacapone for Methamphetamine Abuse
Addiction to methamphetamine is a serious health problem. There are no medications that a doctor can give someone to help them stop using methamphetamine.
- Trial name
- NCT02058966
- Testing
- Entacapone, Methamphetamine
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University