Clinical trials: Metabolism Changes
Thyroid Metabolism
The Reduced Thyroid Function of the Premature Newborn: Relation With Molecular Changes in the Placenta and Maternal Thyroid Hormone Status and Neurodevelopmental Implications
Transient hypothyroxinemia of prematurity (THOP) is a typical entity of the preterm infant, affecting the majority of preterm infants, born less than 30 weeks of gestational age.
- Trial name
- NCT01466023
- Where
- Belgium
- Volunteers
- 319 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Ovarian Cancer
Evaluation of Amino Acid Metabolism Changes in Ovarian Cancer
Ovarian cancer is associated with undernutrition in more than half of all cases. The current management of undernutrition-cachexia in cancer is not specific.
- Trial name
- AMINOCANCER (NCT06216496)
- Testing
- dynamic test for amino acid metabolism
- Where
- France
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Diabetes Mellitus, Type 2, Obesity
Culturally Adapted Dietary Clinical Trial in PR
This project will determine whether a diet culturally adapted to adults in Puerto Rico can effectively decrease cardiometabolic risk factors.
- Conditions
- Diabetes Mellitus, Type 2, Obesity, Hypertension, Dyslipidemias
- Trial name
- PRECISION (NCT05962372)
- Testing
- Culturally tailored food and diet advice, Standard healthy eating advice
- Where
- Puerto Rico
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Obesity, Weight Loss
Bariatric Embolization of Arteries for the Treatment of Nonalcoholic Steatohepatitis
Obesity is an epidemic in the US. With progression of obesity, Nonalcoholic steatohepatitis (NASH) has been a growing public health issue.
- Conditions
- Obesity, Weight Loss, Body Weight, Nonalcoholic Steatohepatitis
- Trial name
- NCT02933554
- Testing
- Embospheres Microspheres
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Keith Pereira, MD:
Weight Loss, Reflux
Mechanism of Weight Loss After Endoscopic and Laparoscopic Sleeve Procedures
The purpose of this research study is to understand the mechanism of weight loss for weight loss procedures: that is Laparoscopic sleeve gastrectomy and Endoscopic sleeve Gastroplasty.
- Trial name
- NCT04006002
- Testing
- Metabolic and Hormonal profile
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Obesity, PreDiabetes
Network Meta-analysis of Intermittent Fasting and Cardiometabolic Risk
Intermittent fasting is a method of restricting calories over a defined period of time and includes regimens such as whole-day fasting, alternate-day fasting, and time-restricted feeding.
- Conditions
- Obesity, PreDiabetes, Diabetes, Hypertension
- Trial name
- NCT05309057
- Testing
- Intermittent Fasting
- Where
- 2 sites in Canada
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Obesity
Effects of Weight Loss on Vascular Function in Obese Subjects
To evaluate the effect of weight loss on vascular function in obese with poor cardiovascular health. The investigators will evaluate the effects of weight loss on total and central body adiposity, blood pressure, central…
- Trial name
- NCT04198519
- Testing
- Weight Loss
- Where
- 2 sites in Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mario Fritsch Neves
Gestational Diabetes, Mobile Application
eHealth in Treatment of Gestational Diabetes (eMOMGDM)
The overall aim of the eMOM GDM-project is to develop and evaluate a novel system to clinical decision making and patient behavior change in treatment of GDM, combining diet, physical activity, sleep, heart rate (e.g.
- Trial name
- eMOMGDM (NCT04714762)
- Testing
- eMOM GDM application
- Where
- Finland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Obesity
Adapted Physical Activity Study
An uncontrolled, non-randomized, open-plan, multi-centre study of treatment and therapeutic education in endocrinology-diabetes-Nutrition that seeks to assess the interest of an adapted physical activity educator for the…
- Trial name
- APA (NCT03337412)
- Testing
- Adapted physical activity
- Where
- France
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Obesity, Osteoporosis
Milk Supplementation and Energy Balance.
The aim of the project is to determine if milk supplementation during a caloric restriction program facilitates the lost of weight, improves the appetite control and attenuates the decrease of bone mineral content in low-calcium…
- Trial name
- NCT00729170
- Testing
- Supplementation of milk (35% more calcium)
- Where
- Canada
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Laval University
Body Weight Changes
Effect of the Administration of L-Carnitine on Body Weight in Women in Crossfit Training
The L-carnitine has demonstrated effects in the treatment of obesity mainly promoting the fat degradation during exercise.
- Trial name
- NCT03436277
- Testing
- L-Carnitine, Sucralose
- Where
- Mexico
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Guadalajara
Overweight and Obesity
Could a Time-restricted Diet Compete With a Calorie-restricted 6-meal Diet?
The prevalence of obesity and obesity-related diseases are on the rise worldwide. The widely accepted approach in dietary treatment of obesity is the calorie-restricted three meals-three snacks a day diet; however, alternative…
- Trial name
- NCT06364475
- Testing
- 16:8 Time-Restricted Intermittent Fasting Group, Energy-Restricted Six-Meal Group
- Where
- Turkey (Türkiye)
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Heart Failure, Overweight and Obesity
Mobile Applet for Weight Management in Obese Heart Failure Patients
The objective of this clinical trial is to investigate the effect of weight reduction through a diet management application and an intelligent weight scale on a composite cardiovascular endpoint in obese patients with heart…
- Conditions
- Heart Failure, Overweight and Obesity, Weight Loss, Heart Failure With Reduced Ejection Fraction
- Trial name
- IDEAL-HF (NCT06455878)
- Testing
- Full usage of diet management app group and with the full usage of an intelligent weight scale, Limited usage of diet management app group and with the limited usage of an intelligent weight scale
- Where
- 26 sites in China
- Volunteers
- 830 people, healthy volunteers welcome
- Sponsor
- Heart Health Research Center
Bone Disease, Metabolic, Osteopenia
Electromagnetic Treatment For Bone Loss After Forearm Fracture
This study will determine the usefulness of pulsing electromagnetic field (PEMF) technology to reverse or reduce the bone loss (osteopenia) that occurs in the forearm after fracture or surgery.
- Conditions
- Bone Disease, Metabolic, Osteopenia, Osteoporosis, Post-Traumatic
- Trial name
- NCT00067834
- Testing
- Pulsing electromagnetic field (PEMF)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Overweight and Obesity
Neurocognitive Benefits of a Weight Management Program
This study will assess whether weight loss induced through diet and physical activity can change neural responses to high- and low-calorie food images.
- Trial name
- NCT04202133
- Testing
- WW (formerly Weight Watchers), Waitlist
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Prediabetic State
Autoimmune Diabetes Accelerator Prevention Trial
The autoimmune diabetes ACCELERATOR PREVENTION TRIAL (adAPT) is based on the accelerator hypothesis. The trial is designed to establish whether metformin, an oral hypoglycaemic agent that is known to reduce insulin demand in type…
- Trial name
- adAPT (NCT02881528)
- Testing
- Metformin Hydrochloride
- Where
- 5 sites in United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Exeter
Obesity
fMRI and Appetite-Related Hormones Pre and Post Obesity Surgery
The investigators are looking at the differences in appetite and obesity between weight loss participants and patients undergoing bariatric surgery.
- Trial name
- NCT01583725
- Testing
- Liquid meal responses, fMRI responses to food-cues
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- New York Obesity and Nutrition Research Center
Dietary Change, Obesity & Overweight
Dietary Peanuts and Nutrition-Related Outcomes
This study will look at how eating peanuts every day might affect participants weight, how healthy their diet is, and how they feel when eating.
- Conditions
- Dietary Change, Obesity & Overweight, Food Acceptance
- Trial name
- NCT07244458
- Testing
- Peanuts, Dual-energy X-ray absorptiometry (DEXA) scans
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Ian J. Neeland, MD
Obesity, Weight Gain
Role of Dairy Products in Weight Maintenance
The goal of the current study is to determine the role of dairy in similarly preventing weight and fat re-gain in obese adults who have successfully completed a weight loss diet program.240 obese subjects will undergo a…
- Trial name
- NCT00686426
- Testing
- Dairy Foods
- Where
- 2 sites in United States
- Volunteers
- 338 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Weight Loss, Bariatric Surgery Candidate
Resting Metabolic Rate Testing in Bariatric Surgery Patients
This study evaluates if measuring resting metabolic rate (the number of calories the body burns at rest) before surgery can help predict successful weight loss after surgery.
- Trial name
- NCT03221543
- Testing
- ReeVue Indirect Calorimeter
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
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