Clinical trials: Metabolic Parameters
Diabetes, Gingivitis
Study on Periodontal Treatment in Diabetic Patients
Diabetes is a metabolic disorder that affects the uptake of glucose into cells. This causes a cascade of systemic alterations that may lead to kidney failure, cardiovascular complications, altered tissue healing, retinopathies…
- Conditions
- Diabetes, Gingivitis, Periodontitis
- Trial name
- NCT01271231
- Testing
- Scaling and root planing plus azythromycin, Prophylaxis plus azythromycin
- Where
- Colombia
- Volunteers
- 90 people
- Sponsor
- Universidad de Antioquia
Diabetes Mellitus, Type 2, Bariatric Surgery Candidate
Restoration of Beta Cell Function and Cardiovascular Parameters in Relation to Adipoinsular and Enteroinsular Axes After Gastric Bypass Surgery
Bariatric operations such as the gastric bypass procedure provide a unique in vivo model of improvement of pathological beta cell function.
- Trial name
- NCT01271062
- Testing
- gastric bypass surgery, abdominal surgery, very low caloric diet
- Where
- 2 sites in Austria, Switzerland
- Volunteers
- 55 people
- Sponsor
- Cantonal Hospital of St. Gallen
PCOS
Myo-inositol Versus D-chiro-inositol in the Treatment of Polycystic Ovary Syndrome and Insulin Resistance: Evaluation of Clinical, Metabolic, Endocrine and Ultrasound Parameters
Insulin resistance has important implications in the pathogenesis of the polycystic ovary syndrome (PCOS) and insulin-sensitizing drugs are considered a useful therapeutic approach.
- Trial name
- NCT01514942
- Testing
- Myo-inositol + Folic acid, D-chiro-inositol, manganese, folic acid, vit B12, Folic acid, vit B12
- Where
- Italy
- Sponsor
- AGUNCO Obstetrics and Gynecology Centre
HIV Infections
The St. Marys and The Mater Switch Study
The aim of the study is to determine whether switching from an antiretroviral regimen containing abacavir and/or didanosine to one containing maraviroc will lead to a reduction in platelet reactivity and inflammatory markers at…
- Trial name
- SMASH (NCT00981773)
- Testing
- Maraviroc
- Where
- 3 sites in Ireland, United Kingdom
- Volunteers
- 18 people
- Sponsor
- Imperial College London
Glucose Parameters, Triglycerides
Investigating the Effects of Glucodia™ on Glucose Parameters, Triglycerides and Body Weight
This study is investigating the effects of 8 weeks of supplementation with Glucodia™, on glucose parameters, triglycerides and body weight as compared to a placebo.
- Conditions
- Glucose Parameters, Triglycerides, Body Weight
- Trial name
- 14GGHF (NCT02322294)
- Testing
- Glucodia™
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- KGK Science Inc.
Type 1 Diabetes
Effects of Vitamin D Supplementation in Subjects With New Onset of Type 1 Diabetes
In this placebo controlled study the investigators aim to investigate the effects of vitamin D supplementation in subjects with new onset of type 1 diabetes on immunological, endocrine and metabolic parameters.
- Trial name
- NCT01390480
- Testing
- Cholecalciferol
- Where
- Austria
- Volunteers
- 31 people
- Sponsor
- Medical University of Graz
Diabetes Mellitus, Type 2
Glycaemic Control and Other Clinical Parameters in Adult Type 2 Diabetes Patients on Basal Insulin Initiating Treatment With IDegLira in Routine Clinical Practice in Colombia
The purpose of this study is to investigate the glycaemic control and other clinical parameters in adult patients previously treated with basal insulin (with or without OADs) and switched to IDegLira in real-world clinical…
- Trial name
- SPIRIT (NCT05324462)
- Testing
- IDegLira
- Where
- 6 sites in Colombia
- Volunteers
- 175 people
- Sponsor
- Novo Nordisk A/S
Healthy, Obesity
A Pharmacokinetic Study to Compare the Dosing of Valproic Acid in Subjects With Different Body Weights
The purpose of this study is to compare the blood levels of valproic acid in subjects with different body weights and to evaluate whether the pharmacokinetic parameters of this drug is altered in the obese population.
- Conditions
- Healthy, Obesity, Pharmacokinetics
- Trial name
- NCT00298857
- Testing
- Valproic acid
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Metabolic Syndrome, Elevated Blood Pressure
Evaluation of a Nigella Sativa Extract (10% Thymoquinone, Nisatol®) in Perimenopausal Women With Metabolic Syndrome
A prospective, multicenter, randomized controlled study evaluating the efficacy and safety of a Nigella sativa extract standardized to 10% thymoquinone (Nisatol®) in perimenopausal women with metabolic syndrome.
- Trial name
- NCT07013058
- Testing
- Nigella sativa extract (Nisatol®), Mediterranean Diet
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Liaquat University of Medical & Health Sciences
Osteopenia, Osteoporosis
Time-specific Exercise in Circadian Context
The project aims to explore the mechanisms, by which physical activity can support healthy ageing and decrease the negative impact of ageing on the circadian system, musculoskeletal system and immunity.
- Conditions
- Osteopenia, Osteoporosis, Aging
- Trial name
- CAEx (NCT06746649)
- Testing
- Combined training
- Where
- Slovakia
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Comenius University
Anaemia
Iron Metabolism in Dragon Boat Athletes
The purpose of the study is: To investigate the effect of sport-specific stress in the iron metabolism of dragon boat athletes To investigate the effects of sport-specific stress in the activity of pro-hepcidin and hepcidin
- Trial name
- NCT01431118
- Testing
- specific dragon boating training intervention, specific dragon boat intervention
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Giessen
Obesity
Acupuncture for Obesity on Serum Metabolic Parameters
This research is planned to build a basis about the effect of acupuncture on serum metabolic parameters in pre-menopausal obese women with economic evaluation.
- Trial name
- NCT02066090
- Testing
- Real acupuncture
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Kyung Hee University Hospital at Gangdong
Healthy, Deficiency Diseases
Creatine Kinase Levels and Clinical and Functional Parameters in Parajiu-jitsu Athletes
Introduction: Evidence indicates that muscle damage caused by exercise can lead to functional, biochemical and clinical damage. Therefore, it is pertinent to perform investigations related to the muscle damage marker, creatine…
- Trial name
- NCT03698578
- Testing
- combat fight
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- São Paulo State University
Overweight Adults
Effects of a Soya-Based Fibre Beverage on Weight and Health in Overweight Adults
The goal of this intervention study is to evaluate the effect of soya-based dietary fiber beverage (SBB) in overweight adults. The main question it aims to answer is: Does the SBB effective in improving the weight and metabolic…
- Trial name
- SBB-WEIGHTLOSS (NCT07614178)
- Testing
- Soya-based dietary fibre beverage
- Where
- Malaysia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Obesity
Effect of Downhill Training on Ankle Joint
Downhill training help to improve musculoskeletal condition. Applying downhill training could help obese children by improving their muscular strength.
- Trial name
- NCT05221268
- Testing
- Level walking exercise, Downhill exercise
- Where
- Saudi Arabia
- Volunteers
- 32 people
- Sponsor
- Taif University
Obesity, Insulin Resistance
Assessing the Value of Red Grapes Polyphenol Supplementation on Metabolic Parameters in Obese Insulinoresistant Subjects
Obesity, chronic disease, is a real public health problem because of its high prevalence but also because of the high risk of complications, including insulin resistance (IR) and type 2 diabetes (T2D).
- Conditions
- Obesity, Insulin Resistance, Menopause
- Trial name
- POLYGIR (NCT02633150)
- Testing
- Supplementation with red grapes polyphenol
- Where
- France
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Type 2 Diabetes Mellitus
Vitamin D Receptor Polymorphisms and Efficacy of Vitamin D-Fortified Yogurt Drink in Patients With Type 2 Diabetes
Study is a 12-week Double blind,controlled experiments designed to examine the possible effects of vitamin D receptor gene polymorphisms on the metabolic, inflammatory and oxidative stress markers in type 2 diabetic patients to…
- Trial name
- NCT01236846
- Testing
- Fortified Yogurt Drink, Plain Yogurt Drink
- Where
- 4 sites in Iran
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Tirang R. Neyestani
Type 2 Diabetes
Characterization of the Variability of Insulin Secretory Parameters in the Meal Tolerance and the Maximal Stimulation Tests of Subjects With Type 2 Diabetes Mellitus
A multi-year clinical study to improve tools for measuring the function of insulin-producing beta cells in people with type 2 diabetes mellitus.
- Trial name
- NCT01663220
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Foundation for the National Institutes of Health
Metabolism, Nutrition
Assessment Metabolic Flexibility in Middle-aged Individuals: The Nutritional Impact of Cheese Consumption
The aim of the study will be to evaluate the impact of consumption of meat and dairy products from extensive or intensive farming on apparently healthy individuals aged between 45 and 65 years, a stage of life associated with…
- Trial name
- Kent'Erbas (NCT06012227)
- Testing
- kent'erbas cheese study
- Where
- Italy
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Cagliari
Renal Transplantion, Kidney Transplantion
A Pilot Trial to Evaluate the Effect of Diet and Exercise in Renal Transplant Recipients on Tacrolimus
The purpose of this trial is to investigate whether a combined dietary and exercise intervention, added to standard care, reduces the expected frequency of insulin resistance in renal (kidney) transplant recipients on tacrolimus.
- Trial name
- PRIDE (NCT00492661)
- Testing
- Tacrolimus With Diet and Exercise Intervention
- Where
- 4 sites in Australia
- Volunteers
- 55 people
- Sponsor
- Janssen-Cilag Pty Ltd