Clinical trials: Mental Resilience
Alzheimer Disease, Early Onset, Posterior Cortical Atrophy
MECHANISMS OF NEURONAL RESILIENCE IN ALZHEIMER'S DISEASE AND ITS FOCAL VARIANTS: A PET/MR STUDY
Patients with Alzheimer's disease and with early onset of symptoms (<65 years) (AD-Y) have a multi-domain cognitive deficit, whereas memory disorders (typical of the elderly patient's AD) are less often in the foreground.
- Trial name
- PET-AL (NCT04150198)
- Testing
- TEP/IRM
- Where
- 2 sites in France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Job Stress, Workplace Stress
Breath Regulation and Yogic Exercise An Online Therapy for Calm and Happiness During the COVID-19 Pandemic
This study will examine the feasibility of conducting an online Randomized Controlled Trial (RCT) in frontline hospital and long term care healthcare staff in managing COVID-19 patients in London, ON.
- Conditions
- Job Stress, Workplace Stress, Compassion Fatigue, Psychological Trauma
- Trial name
- BREATH (NCT04368676)
- Testing
- Sudarshan Kriya Yoga (SKY), Health Enhancement Program
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD)
Stepped Care Treatment for Anxiety Resilience
Childhood anxiety disorders (CAD) are common and impairing. Family based cognitive behavioral therapy (CBT) is efficacious in treating CAD.
- Conditions
- Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD), Separation Anxiety Disorder, Specific Phobia
- Trial name
- STAR (NCT07228143)
- Testing
- Relaxation and Mentorship Training (RMT), Stepped Care Targeting Exposure and Parenting for Anxiety (STEP-A)
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Andrew Wiese
Interpersonal Trauma, Depression
The BEAR Program for Women With Trauma Who Have Suicidal Thoughts
The current study aims to test the feasibility of a new form of group therapy for women who have a history of interpersonal trauma and current suicidal ideation.
- Conditions
- Interpersonal Trauma, Depression, PTSD, Anxiety
- Trial name
- BEAR-SI (NCT07346638)
- Testing
- BEAR-SI
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Stanford University
Resilience, Psychological, Loneliness
Study of Resilience and Loneliness in Youth (18 - 25 Years Old) During the COVID-19 Pandemic Lock-down Measures.
The outbreak linked to SARS-CoV-2 pandemic resulted in lock-down measures in almost all European countries. This online survey assesses these measures implications on Mental Health in emerging adults.
- Conditions
- Resilience, Psychological, Loneliness, Youth, Surveys and Questionnaires
- Trial name
- NCT04371250
- Testing
- Survey and Questionnaire
- Where
- Belgium
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Erasme University Hospital
Alcohol Use Disorder
Methylphenidate and Response to Alcohol Cues
The purpose of this study is to determine whether changes in attention levels related to taking a single dose of a medication called methylphenidate, also known as Ritalin, affects responses to alcohol cues.
- Trial name
- NCT07306078
- Testing
- Methylphenidate Pill
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Florida
Childhood Cancer, Depressive Symptoms
Cultivating Resilience in Oncology Practice
The purpose of the CROP study is to investigate the potential to cultivate psychological resources and resilience in childhood cancer patients and their family members using a mobile phone-based intervention.
- Conditions
- Childhood Cancer, Depressive Symptoms, Anxiety Disorders and Symptoms, Mental Health Issue
- Trial name
- CROP (NCT04902313)
- Testing
- Awareness and insight Modules (AiM)
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Linkoeping University
Cancer, Quality of Life
The PRISM Intervention: a Multi-site Randomized Controlled Trial for Adolescents and Young Adults With Advanced Cancer
Multi-Site Randomized Controlled Trial testing the efficacy of the Promoting Resilience in Stress Management (PRISM) intervention among Adolescents and Young Adults with Advanced Cancer
- Conditions
- Cancer, Quality of Life, Anxiety, Depression
- Trial name
- PRISM-AC (NCT03668223)
- Testing
- Promoting Resilience in Stress Management (PRISM)
- Where
- 5 sites in United States
- Volunteers
- 269 people
- Sponsor
- Dana-Farber Cancer Institute
Psychological Stress, Psychological Distress
Mind and Body:A Clinical Trial Evaluation of a Smartphone App-based Mindfulness Intervention
This study evaluates the use of a mobile-app delivered mindfulness-based intervention for supporting psychosocial resilience in aging patients undergoing rehabilitation treatment.
- Conditions
- Psychological Stress, Psychological Distress, Rehabilitation
- Trial name
- NCT03908918
- Testing
- Mindfulness app
- Where
- Canada
- Volunteers
- 11 people
- Sponsor
- Providence Healthcare
Mood Disorders, Depression
Effects of Omega-3 EPA/DHA for Soldiers at Risk for Mood Disorders
Stress-related disorders are among the most prevalent and expensive medical consequences of participation in military operations.
- Conditions
- Mood Disorders, Depression, Combat Disorders, Stress Disorders
- Trial name
- NCT01216982
- Testing
- Lovaza, omega-3 fatty acid ethyl ester
- Where
- Iraq
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- United States Department of Defense
PTSD, Recent Era Combat Veteran
UCLA Couples Counseling for Combat Veterans
A pilot intervention of an existing intervention adapted for the returning warfighter population: a couples treatment for PTSD, Structured Approach Therapy (SAT), which emphasizes reducing the PTSD avoidance/numbing symptoms that…
- Conditions
- PTSD, Recent Era Combat Veteran, Couples Communication
- Trial name
- CCCV (NCT01627548)
- Testing
- Structured Approach Therapy
- Where
- United States
- Sponsor
- University of California, Los Angeles
Military Sexual Trauma, Intimate Partner Violence
Multifaceted Intervention to Restore Resilience and Overcome Risk
The MIRROR study will compare the effectiveness of two interventions in improving emotion regulation and reducing PTSD symptoms in female Veterans with military sexual trauma (MST) and/or intimate partner violence (IPV) and…
- Conditions
- Military Sexual Trauma, Intimate Partner Violence, Brain Injury, Post Traumatic Stress Disorder
- Trial name
- MIRROR (NCT06988787)
- Testing
- webSTAIR, ExpoTx, PsychoEd
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Post Intensive Care Syndrome, Family Members
Incidence and Factors Associated to the Development of PICS-F Among ICU Relatives: A Longitudinal Exploratory Study
The constellation of long-term psychological, physical, and cognitive impairments arising after a critical illness among family members of ICU survivors has been labeled as "Post Intensive Care Syndrome - Family" (PICS-F).
- Conditions
- Post Intensive Care Syndrome, Family Members, Caregiver Burden, Critical Illness
- Trial name
- NCT05827354
- Where
- Chile
- Volunteers
- 175 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Stress Management, Perceived Stress
The Effectiveness of Stress Management Training on Perceiving and Coping With Stress and Developing Resilience
Associate degree students studying in the field of health perform their professions in the status of intermediate staff related to health in our country.
- Conditions
- Stress Management, Perceived Stress, Coping Strategy, Psychological Resilience
- Trial name
- NCT06502314
- Testing
- Stress management training
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Stress, Psychological
Self Help Intervention to Decrease Stress
The present study is designed to test the feasibility and efficacy of a stand alone self help program for decreasing stress and anxiety and enhancing quality of life.
- Trial name
- NCT01242865
- Testing
- Attention and Interpretation Therapy
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Alcohol Use Disorder, Stress Reaction
Neurobehavioral Profiles of Adaptive Stress Responses in Individuals With Alcohol Use Disorder
The goal of this observational study is to investigate longitudinal stress response profiles and adaptive versus non-adaptive stress responses in alcohol use disorder.
- Conditions
- Alcohol Use Disorder, Stress Reaction, Social Stress, Craving
- Trial name
- A03 (NCT06105853)
- Testing
- Trier Social Stress Test, Barlab Cue-Exposure, Functional magnetic resonance imaging
- Where
- 2 sites in Germany
- Volunteers
- 100 people
- Sponsor
- Central Institute of Mental Health, Mannheim
Mindfulness Training, Cardiac Resynchronization Therapy Devices
Efficacy of a Mindfulness-Based Intervention in Patients With Cardiovascular Implantable Electronic Device
An implantable cardiac defibrillator (implantable cardioverter-defibrillator; ICD) can effectively improve heart rhythm problems and reduce sudden death, and is widely used in the treatment of high-risk patients with fatal…
- Conditions
- Mindfulness Training, Cardiac Resynchronization Therapy Devices, Resilience, Psychological, Anxiety
- Trial name
- MBI-CIED (NCT06021236)
- Testing
- mindfulness-based intervention, CIED procedure routine care
- Where
- Taiwan
- Volunteers
- 34 people
- Sponsor
- Chien Chih-Yin
Schizophrenia
The Effect of Developing Psychological Resilience on Functionality in Schizophrenia Patients
People with schizophrenia have low functionality and psychological resilience. Psychological resilience of individuals can be improved. The funcionality of individual with improved psychological resilience can also be improved.
- Trial name
- NCT05739344
- Testing
- Cognitive behavioral approach based resilience development program for schizophrenic individuals
- Where
- Turkey (Türkiye)
- Volunteers
- 13 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Major Depressive Disorder
Pilot Study of Duloxetine in Psychological Resilience
The purpose of this study is to explore benefits of duloxetine in enhancing psychological resilience and to understand the relevance of inhibiting of both serotonin (5HT) and norepinephrine (NE)to therapeutic responses.
- Trial name
- NCT00331799
- Testing
- Duloxetine
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Duke University
HIV Pre-exposure Prophylaxis, HEPATITIS C (HCV)
Trauma-informed, Resilience-based Telehealth Intervention for Improving HIV Prevention and HCV Care for Persons Who Inject Drugs in the Deep South (Pilot Testing: Aim3)
Evaluate the feasibility, acceptability, and usability of the intervention (primary outcomes) and coping skills and resilience (secondary outcomes) of the telehealth intervention over two months (8 weekly sessions) in a…
- Conditions
- HIV Pre-exposure Prophylaxis, HEPATITIS C (HCV), Opioid Use Disorder
- Trial name
- NCT06799702
- Testing
- Telehealth Behavioral Intervention for promoting HIV and HCV care and MOUD among Persons who inject drugs (PWID)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Georgia