Clinical trials: Mental Health (Depression)
Depression, Problematic Alcohol Use
Scaling Up Science-based Mental Health Interventions in Latin America
Conduct systematic, multi-site mental health implementation research in both rural and urban primary care settings with a broad group of stakeholders in the US and Latin America.
- Trial name
- DIADA (NCT03392883)
- Testing
- Laddr
- Where
- 6 sites in Colombia
- Volunteers
- 1,348 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Mental Health Wellness 1, Depression
Designing a Mental Health Model for Latina Women
The goal of this study is to implement such an approach conceptualized by a community health worker (CHW) to pilot an innovative, multi-level intervention to address social and structural determinants that negatively influence…
- Trial name
- NCT03901430
- Testing
- Group navigation model
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Pregnancy Related, Stress, Psychological
The Stony Brook University Calm-Mom Study
The present trial will evaluate the feasibility, acceptability and preliminary efficacy of 2 different internet-delivered programs for prenatal maternal stress.
- Conditions
- Pregnancy Related, Stress, Psychological, Anxiety, Perinatal Depression
- Trial name
- NCT04018625
- Testing
- SMART Mom, Mama Support
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Stony Brook University
Depression, Postpartum, Depression, Unipolar
Tracking Depression Symptoms With a Health Chatbot
The goal of this research is to bridge a significant "effectiveness" gap in the treatment of depression. The investigators have developed a chatbot which will assist in performing measurement-based care (MBC) via Facebook…
- Trial name
- NCT03990389
- Testing
- Chatbot Intervention
- Where
- 2 sites in United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Depression, Anxiety
Potency and Precision Investigation
The overarching goal of this study is to establish initial proof of mechanism for precision interventions in an adult population.
- Trial name
- PAPI (NCT06240091)
- Testing
- DISC-MA
- Where
- United States
- Volunteers
- 203 people
- Sponsor
- Woebot Health
Chronic Low-back Pain, Anxiety
EaseVRx-8w+ for the Treatment of Chronic Lower Back Pain
The aim of this randomized controlled trial (RCT) is to assess outcomes for virtual reality therapy (including pain intensity, pain interference, anxiety, depression, physical function, sleep, behavioral skills development…
- Conditions
- Chronic Low-back Pain, Anxiety, Depression
- Trial name
- AVR_HEOR (NCT05263037)
- Testing
- EaseVRx
- Where
- United States
- Volunteers
- 1,093 people
- Sponsor
- AppliedVR Inc.
Medication Adherence, Depressive Symptoms
Testing THRIVE 365 for Black Sexual Minority Men (On The Daily)
The primary goal of this study is to test a minority stress model of psychological health outcomes for Black sexual minority men (BSMM) while using and not using a novel intervention named THRIVE 365.
- Conditions
- Medication Adherence, Depressive Symptoms, Anxiety Symptoms, Emotion Regulation
- Trial name
- OTD (NCT05376397)
- Testing
- iTHRIVE 365
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Anxiety Depression
Mobile Health and COVID-19
The proposed research focuses on evaluating the mobile application, Easing Anxiety Sensitivity for Everyone (EASE), to improve overall public health that concerns risks and mental health status during the coronavirus disease of…
- Trial name
- NCT05074693
- Testing
- EASE app, INSIGHT (Control) App
- Where
- 2 sites in United States
- Volunteers
- 822 people, healthy volunteers welcome
- Sponsor
- University of Houston
Major Depressive Disorder
The Effects of Videogames on Depression Symptoms and Brain Dynamics
The purpose of the study is to evaluate the effects of a game-based digital-therapeutics (DTx) medical software device on the symptoms of depression in adults with confirmed major depressive disorder.
- Trial name
- NCT05426265
- Testing
- MEL-T01, MEL-S01
- Where
- 6 sites in Finland
- Volunteers
- 1,001 people, healthy volunteers welcome
- Sponsor
- Aalto University
Mild Traumatic Brain Injury, Posttraumatic Stress Disorders
Multifamily Group to Reduce Marital Conflict and Disability in Veterans With mTBI
This project addresses the rehabilitation and mental health needs of married combat Veterans post-deployed from Iraq or Afghanistan with a mild traumatic brain injury (mTBI) and/or significant posttraumatic stress (PTS) or…
- Conditions
- Mild Traumatic Brain Injury, Posttraumatic Stress Disorders, Depression
- Trial name
- MFG-mTBI (NCT02057081)
- Testing
- Multifamily Group for mTBI for Couples, Group Health Education (GHE)
- Where
- 3 sites in United States
- Volunteers
- 249 people
- Sponsor
- VA Office of Research and Development
Anxiety Depression, Disability Physical
Exploratory Study for Toivoa-001 on Human Factors
The Study will evaluate Rauha as an experimental digital therapeutic for persons with Disabilities suffering from anxiety and/or depression.
- Trial name
- NCT06477913
- Testing
- Rauha
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Toivoa Inc
Depression, Depressive Symptoms
Evaluation of a Proactive Identification and Digital Mental Health Intervention Approach to Address Unmet Psychosocial Needs of Individuals Living With Cancer
The purpose of this research study is to evaluate a mobile application (app) for depression treatment called "Moodivate" among cancer survivors.
- Conditions
- Depression, Depressive Symptoms, Cancer
- Trial name
- NCT05932810
- Testing
- Behavioral Activation Therapy app, Treatment as Usual
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Medical University of South Carolina
Anxiety Disorder, Cognitive/Functional Effects
Health Education Materials With/Out a Physical Activity Program for Patients Who Have Undergone Treatment for High-Risk Stage II or Stage III Colon Cancer
RATIONALE: Participating in a physical activity program designed to increase free time physical activity and receiving written health education materials may influence the chance of cancer recurring as well as impact on physical…
- Conditions
- Anxiety Disorder, Cognitive/Functional Effects, Colorectal Cancer, Depression
- Trial name
- CHALLENGE (NCT00819208)
- Testing
- exercise intervention, counseling intervention, educational intervention
- Where
- 47 sites in United States, Australia and 4 more
- Volunteers
- 889 people
- Sponsor
- Canadian Cancer Trials Group
Depressive Disorder, Depression
Telephone Administered Psychotherapy for the Treatment of Depression for Veterans in Rural Areas
The purpose of this study is to examine the efficacy of telephone-administered cognitive-behavioral therapy (T-CBT) in treating major depression among veterans served by community-based outpatient clinics (CBOCs) in the Veteran's…
- Trial name
- NCT00223652
- Testing
- Telephone cognitive behavioral therapy
- Where
- 3 sites in United States
- Volunteers
- 85 people
- Sponsor
- US Department of Veterans Affairs
Post-traumatic Stress Disorder, Traumatic Brain Injury
Multisite RCT of STEP-Home: A Transdiagnostic Skill-based Community Reintegration Workshop
In this proposal, the investigators extend their previous SPiRE feasibility and preliminary effectiveness study to examine STEP-Home efficacy in a RCT design.
- Conditions
- Post-traumatic Stress Disorder, Traumatic Brain Injury, Substance Related Disorders, Depression
- Trial name
- STEP-Home (NCT03868930)
- Testing
- STEP-Home, PCGT
- Where
- 2 sites in United States
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
COVID-19, Pregnancy Complications
Health and Wellbeing of Pregnant and Post-Partum Women During the COVID-19 Pandemic
The purpose of this study is to assess the health and wellbeing of pregnant and recently pregnant women during the COVID-19 pandemic using an online survey.
- Conditions
- COVID-19, Pregnancy Complications, Mental Health Wellness 1, Anxiety
- Trial name
- NCT04385238
- Testing
- This is an online survey with no intervention.
- Where
- United States
- Volunteers
- 6,894 people
- Sponsor
- Pregistry
Anxiety Disorders, Depressive Disorder
Harnessing Mobile Technology to Reduce Mental Health Disorders in College Populations
The prevalence of mental health problems among college populations has risen steadily in recent decades, with one third of today's students struggling with anxiety, depression, or an eating disorder (ED).
- Conditions
- Anxiety Disorders, Depressive Disorder, Eating Disorders
- Trial name
- iAIM EDU (NCT04162847)
- Testing
- SilverCloud Health Intervention
- Where
- 4 sites in United States
- Volunteers
- 6,205 people
- Sponsor
- Washington University School of Medicine
Depression in Adolescence
Evaluation of MoodRing on Improving the Quality of Depression Management in Adolescents
The MoodRing intervention is a mobile application for adolescents, parents, and an accompanying web-based clinician portal which enables adolescents to monitor their mood through the use of passively collected smartphone data.
- Trial name
- TECH-E (NCT05376358)
- Testing
- MoodRing App, Usual Care
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Ana Radovic
Depression, Anxiety
A Transdiagnostic Course for Common Mental Health Problems in Primary Care
This study investigates the feasibility of a transdiagnostic course that is intended to work for a large variety of patient groups with clinically significant depression or anxiety in primary care.
- Trial name
- NCT04522713
- Testing
- Behavioral activation, evidence-based sleep strategies including sleep restriction, exposure-based strategies, promotion of physical activity and recuperating activities, psychoeducational material
- Where
- 2 sites in Sweden
- Volunteers
- 91 people
- Sponsor
- Karolinska Institutet
Major Depressive Disorder
Evaluation of a Mental Health Physician Support Program in Nova Scotia
The aim of this study is to test the program's effectiveness in a primary care setting in reducing stigma among medical personnel, increasing the comfort level of physicians and staff in providing care to those living with mental…
- Trial name
- NCT01975948
- Testing
- Mental Health Practice Support Program, Treatment as Usual
- Where
- Canada
- Volunteers
- 285 people
- Sponsor
- Nova Scotia Health Authority