Clinical trials: Mental Disorder, open to volunteers
Inflammation, Depression Disorder
Inflammatory Pathways Modulated by Prenatal Mindfulness: A Route to Improve Maternal Child Emotional Well Being and Whole Person Health
The goal of this study is to investigate inflammation as the biological mechanism by which mindfulness based cognitive therapy for perinatal depression (MBCT-PD) administered during pregnancy improves women's emotional well-being…
- Conditions
- Inflammation, Depression Disorder, Mindfulness, Emotional Well-being
- Trial name
- NCT07892326
- Testing
- Mindfulness-based cognitive therapy for perinatal depression, Pregnancy Health Group
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Oregon Health and Science University
Psychiatric Disorder
Pilot Study on the Acceptability of Auricular Vagus Nerve Neurostimulation in Adolescents
Non-suicidal self-injury (NSSI) are acts defined by the DSM-5 (Diagnostic and Statistical Manual of Mental Disorders 5) as intentional and deliberate, occurring outside a psychotic state and directly causing moderate injury.
- Trial name
- NEUROMUTE (NCT06433583)
- Testing
- transcutaneous auricular vagal nerve stimulation
- Where
- 2 sites in France
- Volunteers
- 22 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Parenting Stress, Mental Health
Development & Validation of a Life Balance Program for Parents of Preschoolers: A Pilot Study
This study aims to examine the relationships among life balance, parenting stress, and mental health in parents of preschool children, and to develop an individualized life balance promotion program for this population.
- Conditions
- Parenting Stress, Mental Health, Occupational Balance
- Trial name
- NCT07669896
- Testing
- Occupational Balance Promotion Program
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Psychiatric Disorder, Involuntary Psychiatric Hospitalization
A Brief Case Management Intervention to Promote Personal Recovery and Prevent Psychiatric Involuntary Readmissions.
The goal of this randomized control trial is to assess the effectiveness of a Brief Case Management (BCM) intervention aimed at promoting personal recovery and reducing the negative effects of coercion among people involuntarily…
- Trial name
- CARP-RCT (NCT07497763)
- Testing
- Brief Case Management intervention, TAU
- Where
- Switzerland
- Volunteers
- 262 people
- Sponsor
- Stéphane Morandi
Severe Mental Illness
Supporting Older Adults Remotely
The Supporting Older Adults Remotely (SOAR) study is a randomized controlled trial evaluating a 12-week, telephone-delivered peer support intervention for adults age 50 and older with serious mental illness who live in supportive…
- Trial name
- SOAR (NCT07878169)
- Testing
- Supporting Older Adults Remotely (SOAR), Peer support as usual
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Severe Mental Illness, Hospitalizations Psychiatric
Community-Based Intensive Treatment (CBIT): Meeting the Complex Needs of Rural Adults With Serious Mental Illness
The purpose for this research project is to successfully achieve the primary systems intervention outcome, maintaining fidelity to the intervention model and time to rehospitalization.
- Conditions
- Severe Mental Illness, Hospitalizations Psychiatric, Rural Healthcare-seeking Behaviour, Rural Health
- Trial name
- CBIT (NCT07887113)
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Yale University
Disruptive Behaviors
Hybrid Pilot of Personalized Parent-Child Interaction Therapy
The goal of this clinical trial is to learn whether a personalized version of Parent-Child Interaction Therapy (PCIT), called MY PCIT, can improve treatment fit, treatment participation, and outcomes for young children with…
- Trial name
- PCIT (NCT07887295)
- Testing
- Behavioral Parent Training
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- San Diego State University
Depressive Symptoms, Anxiety Disorders and Symptoms
Family Spirit Strengths
This project addresses the disproportionate morbidity and mortality associated with mental and behavioral health problems in American Indian and Alaska Native communities.
- Conditions
- Depressive Symptoms, Anxiety Disorders and Symptoms, Substance Use, Mental Health Issue
- Trial name
- FSS (NCT05836090)
- Testing
- Family Spirit Strengths (FSS), Family Spirit Nurture
- Where
- 3 sites in United States
- Volunteers
- 188 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Diabete Mellitus, Dyslipidaemia
Prevalence and Associated Factors of High BMI and Periodontitis in Thai Adults Aged Under 60 Years
Overweight and obesity, as well as periodontitis, are common public health problems with increasing prevalence. Both conditions may be linked through shared mechanisms involving chronic low-grade systemic inflammation.
- Conditions
- Diabete Mellitus, Dyslipidaemia, Chronic Kidney Disease, Psychiatric Disorder
- Trial name
- NCT07880717
- Testing
- Periodontal Examination, Questionnaire interview, Anthropometric measurements
- Where
- Thailand
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Substance Use Disorder, Mental Illness
Successful Transitions and Reintegration Tools for Veterans (START-VETS)
This study will develop prison reentry materials for Veterans leaving prison.
- Conditions
- Substance Use Disorder, Mental Illness, Recently Incarcerated
- Trial name
- START-VET (NCT04366531)
- Testing
- START-VET, Treatment as usual
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
Virtual Reality Viewing of Unaltered Streetscape Versus Digitally Manipulated Opposite Streetscape to Assess Psychosocial Response in Participants
This clinical trial compares virtual reality viewing of an unaltered streetscape versus a digitally manipulated opposite streetscape to assess the psychosocial response in participants.
- Conditions
- Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm, Psychiatric Disorder
- Trial name
- NCT07216534
- Testing
- Survey Administration, Virtual Technology Intervention
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Schizophenia Disorder, Severe Mental Illness
Effect of Occupational Therapy on Psychosocial Parameters and Functioning in Individuals With Severe Mental Illness
Severe mental illness (SMI), including schizophrenia spectrum disorders and bipolar disorder, is associated with significant impairments in psychosocial functioning, daily life participation, self-efficacy, and social…
- Conditions
- Schizophenia Disorder, Severe Mental Illness, Bipolar Disorder, Nonorganic Psychosis
- Trial name
- OT-SMI (NCT07879118)
- Testing
- Occupational Therapy Group Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Biruni University
Severe Mental Illness, Bipolar Disorder
A Mobile App to Support Mood, Daily Routines and Medication Adherence in Adults With Severe Mental Illness
The goal of this clinical trial is to learn whether MoodSync, a mobile application for patients and their family caregivers, improves mood stability, medication adherence, daily functioning and early detection of relapse warning…
- Conditions
- Severe Mental Illness, Bipolar Disorder, Schizophrenia, Schizoaffective Disorder
- Trial name
- MoodSync (NCT07879131)
- Testing
- MoodSync, Standard care
- Where
- Bahrain
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Serious Mental Illness, Tobacco Use Disorder
Facilitation to Increase Tobacco Treatment
Smoking disproportionally impacts Veterans, and VA spends $2.7 billion annually on smoking-related health conditions. Veterans with serious mental illness (SMI) smoke tobacco products at triple the rate of Veterans without any…
- Trial name
- FITT (NCT07455526)
- Testing
- Multi-component facilitation
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- VA Office of Research and Development
Schizophrenia
A Long-Term Open-Label Study of ML-007C-MA in Adults With Schizophrenia
ML-007C-MA-212 is a 52-week open-label study designed to evaluate the long-term safety, tolerability, and effectiveness of ML-007C-MA in participants with schizophrenia who have recently completed an antecedent study…
- Trial name
- NCT07459647
- Testing
- ML-007C-MA
- Where
- 45 sites in United States
- Volunteers
- 500 people
- Sponsor
- MapLight Therapeutics
Implementation Science, Chronic Disease Self-management
Adapting and Implementing a Chronic Disease Self-Management Program for Primary Care Patients With Opioid Use Disorder and Serious Mental Illness
The purpose of this study is to evaluate a self-management education program designed to help people with opioid use disorder (OUD), serious mental illness (SMI), and other chronic health conditions better manage their health.
- Conditions
- Implementation Science, Chronic Disease Self-management, Mental Illness, Addiction
- Trial name
- NCT07865078
- Testing
- The Chronic Disease Self-Management Program (CDSMP), Treatment as Usual plus self-management information
- Volunteers
- 40 people
- Sponsor
- University of Utah
Mental Health Care, Anxiety and Depression
Feasibility and Acceptability of Group Medical Visits for Anxiety and Depression
The goal of this clinical trial is to evaluate the feasibility and acceptability of the intervention, Group Medical Visits (GMVs), for patients with depression and anxiety.
- Conditions
- Mental Health Care, Anxiety and Depression, Pilot Study
- Trial name
- NCT06651801
- Testing
- Group Medical Visits
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Manitoba
Opioid Use Disorder, Mental Health Disorder
Supporting Treatment Access and Recovery in COD
This 4-year study will randomize 1,000 people with co-occurring opioid use and mental health disorders (COD) at medication for opioid use disorder (MOUD) clinics to evaluate the effectiveness of MISSION, a multi-component team…
- Trial name
- STAR-COD (NCT05138614)
- Testing
- Medication for Opioid Use Disorder, MISSION Critical Time Intervention, MISSION Peer Support
- Where
- 5 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- University of Massachusetts, Worcester
Depression, Unipolar
FMRI-neurofeedback in Depression
Previous studies with fMRI-neurofeedback in depression have demonstrated a good safety profile and considerable symptom reduction.
- Trial name
- NCT05640089
- Testing
- fMRI-based neurofeedback
- Where
- 3 sites in Netherlands
- Volunteers
- 120 people
- Sponsor
- Maastricht University Medical Center
Psychiatric Disorders, Anxiety Disorders
Gaze-Contingent Music Therapy Augmentation of CBT for Pediatric Anxiety
Background: Anxiety disorders are becoming more common among children and teenagers. Anxiety can lead to long-term physical and mental problems, such as depression.
- Trial name
- NCT06595953
- Testing
- Gaze-Contingent Music Reward Therapy
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- National Institute of Mental Health (NIMH)