Clinical trials: Menstrual Cycles
Postoperative Sensitivity, Rebound Pain
Menstrual Cycle Effects on Postoperative Sensitivity and Rebound Pain in Composite Restorations
This study aims to evaluate how different phases of the menstrual cycle affect pain after dental treatments. Specifically, it investigates two types of pain: Postoperative sensitivity (pain felt after the filling procedure), and…
- Conditions
- Postoperative Sensitivity, Rebound Pain, Menstrual Cycle, Composite Restorations
- Trial name
- NCT06886243
- Testing
- Direct Posterior Composite Restoration
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Firat University
Uterine Fibroids, Leiomyoma
An Open-Label Study to Evaluate the Effect of Elix Cycle Balance & Elix Daily Harmony on Fibroid-related Symptoms
This is a 24-week, single-arm, open-label, virtual study evaluating the effects of Elix Cycle Balance and Elix Daily Harmony on uterine fibroid-related symptoms and quality of life in 42 participants.
- Conditions
- Uterine Fibroids, Leiomyoma, Menstrual Pain
- Trial name
- NCT07078682
- Testing
- Elix Daily Harmony
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Zenchi, Inc.
Grip, Athlete
Hand Grip Strength in Athletic and Non-Athletic Girls at Different Phases of Menstrual Cycle
The study was designed as an observational study
- Conditions
- Grip, Athlete, Non-athlete, Menstrual Cycle
- Trial name
- NCT06086262
- Testing
- Hydraulic hand dynamometer (Jamar, Product model J00105, U.S.A)
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Heba Ahmed Mohamed Ahmed
Polycystic Ovary Syndrome
Simvastatin and Metformin Therapy in PCOS Women. Prospective Randomised Trial.
The purpose of this study is to compare effects of statins (simvastatin) and metformin on clinical (menstrual cycle, excessive hair, skin problems), endocrine (androgens), metabolic (lipids, markers of systemic inflammation), and…
- Trial name
- NCT00396513
- Testing
- Simvastatin, Simvastatin and Metformin, Metformin
- Where
- Poland
- Sponsor
- Poznan University of Medical Sciences
Breast Cancer, Perioperative/Postoperative Complications
Correlation of Menstrual Cycle Phase at Time of Primary Surgery With 5-Year Disease-Free Survival in Women With Stage I or Stage II Breast Cancer
RATIONALE: Timing of breast cancer surgery may improve effectiveness of treatment and may help patients live longer. PURPOSE: Clinical trial to determine whether timing of primary surgery in relation to menstrual cycle is…
- Trial name
- NCT00002762
- Testing
- patient interviewing to obtain menstrual history, blood sampling
- Where
- 54 sites in United States, Canada
- Volunteers
- 1,118 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Menstrual Cycle, Achilles Tendon
Effects of the Menstrual Cycle on Triceps Surae Properties in Women
The menstrual cycle is an important biological rhythm, whereby large cyclic fluctuations in endogenous sex hormones, such as estrogen and progesterone, are observed, which can affect performance.
- Trial name
- NCT06214442
- Testing
- Evaluations of the mechanical properties of the achilles tendon in different phases of the menstrual cycle
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Marco Aurélio Vaz, PhD
PMS, Menstrual Pain
Study to Evaluate the Efficacy of Elix's Cycle Balance and Its Impact on PMS and Menstrual Symptoms
This is an open-label observational single-group clinical trial to study the efficacy of a commercially available dietary supplement and its effect on common PMS and menstrual symptoms.
- Trial name
- NCT05145257
- Testing
- Elix Cycle Balance
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Zenchi, Inc.
Postmenopausal, Premenopausal
Oxytocin in Postmenopausal Women
The aim of the present study is to assess whether cumulative endogenous neurophysin I secretion over one month differs between premenopausal and postmenopausal women.
- Trial name
- OxyMENO (NCT07742124)
- Testing
- Repeated assessments
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- University Hospital, Basel, Switzerland
Dysmenorrhea Primary, Pain
Effects of Transcutaneous Vagus Nerve Stimulation (taVNS) in Individuals With Primary Dysmenorrhea
This study aims to investigate the effects of transcutaneous auricular vagus nerve stimulation (taVNS) on pain, functional and emotional symptoms, and physical performance in individuals with primary dysmenorrhea (PD).
- Trial name
- NCT06146569
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation (taVNS)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Artvin Coruh University
Premenstrual Syndrome, Mastodynia
Efficacy and Safety of 20 mg (2 Tablets of 10mg)VAC BNO 1095 FCT on Cyclic Mastodynia and PMS
The purpose of this study is to proof the efficacy and safety of 20 mg (2 tablets of 10 mg) VAC BNO 1095 film-coated tablets in patients suffering from cyclic mastodynia and PMS (pre menstrual syndrome).
- Trial name
- NCT01870687
- Testing
- 20mg VAC BNO 1095 FCT
- Where
- Germany
- Volunteers
- 96 people
- Sponsor
- Bionorica SE
Ovulation
Heart Rate Variability During the Menstrual Cycle
In this study, women will be required to wear a chest heart rate monitor and wrist heart rate monitor daily and collect daily early morning urine samples for the duration of one complete menstrual cycle.
- Trial name
- NCT04382001
- Where
- United Kingdom
- Volunteers
- 28 people
- Sponsor
- SPD Development Company Limited
Nicotine Dependence, Tobacco Smoking
Smoking Cessation and Menstrual Cycle Phase
Tobacco use is a risk factor for at least 20 types of cancer and remains the leading preventable cause of cancer in Canada. Smoking cessation is an important cancer prevention strategy for the close to 2 million Canadian women…
- Conditions
- Nicotine Dependence, Tobacco Smoking, Smoking Cessation, Nicotine Use Disorder
- Trial name
- MC-NRT (NCT05515354)
- Testing
- Timing of nicotine replacement therapy start date, Nicotine Replacement Therapy Agent
- Where
- Canada
- Volunteers
- 1,200 people
- Sponsor
- Centre for Addiction and Mental Health
Menorrhagia
Lysteda Pediatric Research Equity Act (PREA) Pharmacokinetic Study in Adolescent Females With Heavy Menstrual Bleeding
This is a Phase 4, randomized, 2-way crossover, pharmacokinetic study of Lysteda (tranexamic acid) tablets administered as single doses of 0.65 g and 1.3 g in fasting adolescent female subjects ages 12-16 years with heavy…
- Trial name
- PREA (NCT01190150)
- Testing
- tranexamic acid
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Ferring Pharmaceuticals
Menstrual Cycle, Oral Contraceptive Use
Effects of the Menstrual Cycle and Oral Contraceptive Use on Health and Performance in Athletes
A review of the sports medicine literature reveals a clear underrepresentation of female athletes in research. In the current era of precision medicine, increasing attention has been directed toward the regulatory roles of…
- Conditions
- Menstrual Cycle, Oral Contraceptive Use, Athlete
- Trial name
- Flow2Perform (NCT07591818)
- Where
- Portugal
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Faculdade de Motricidade Humana
Heavy Menstrual Bleeding
Delivering tAN to Reduce HMB: The LUNA Study
The LUNA study is a prospective, randomized, double-blind, sham-controlled, decentralized clinical trial in participants with heavy menstrual bleeding of no known structural cause.
- Trial name
- LUNA (NCT07326722)
- Testing
- Sparrow Link
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Spark Biomedical, Inc.
Extracellular Vesicles
Isolation and Characterization of the Extracellular Vesicles Secreted by the Human Endometrium
The main aim of this study is to describe the morphology, size distributions and specific markers of the different vesicles populations present in the human endometrial fluid.
- Trial name
- NCT02797834
- Testing
- Endometrial fluid collection
- Where
- Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Igenomix
Neural Activity, Brain Function
Whole-Brain Dynamics in the Natural Menstrual Cycle vs. an Ovarian Stimulated Cycle: Impact of Hormonal Fluctuations on Healthy Women Undergoing Ovarian Stimulation
The investigators aim is to investigate the brain's dynamic complexity across three phases of an ovarian stimulation cycle (basal, pre-OPU, mid-luteal), to observe the impact of externally administered hormones, and compare it…
- Conditions
- Neural Activity, Brain Function, Neurodynamics, Brain Connectivity
- Trial name
- NCT06910293
- Testing
- Functional Magnetic resonance imaging will be done on day 2 or 3 of the menstrual cycle, trigger-shot and egg retrieval.
- Where
- 2 sites in United Arab Emirates
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Uterine Adenomyosis, Recurrent Implantation Failure
Aromatase Plus GnRH Analogue Versus GnRH Analog Alone in Adenomyosis
With this study the investigators want to test which is the best medical treatment for symptomatic adenomyosis affecting women undergoing IVF and with previous implantation failure, between Aromatase inhibitor plus GnRH analog…
- Conditions
- Uterine Adenomyosis, Recurrent Implantation Failure, Menstrual Pain
- Trial name
- NCT03421639
- Testing
- GnRH analog (11.25mg Leuprolide acetate), Aromatase inhibitor and GnRH analog, Aromatase and GnRH analog (11.25mg Leuprolide acetate)
- Where
- 3 sites in Albania, Bulgaria and 1 more
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Centre for Endocrinology and Reproductive Medicine, Italy
Menstrual Cycle
The Effect of Menstruation on Food Preference and Balance
Menstruation period, which is accepted as the symbol of fertility, and some problems related to this process covers half of a woman's life.
- Trial name
- NCT05821439
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Circulatory; Change
Changes in Breast 3D Ultrasound Measurements Using Toremifene
To investigate if there are detectable changes in volume and circulation in breasts of healthy volunteers using toremifene 20 mg in luteal phase of the menstruation cycle versus nonmedicated cycle.
- Trial name
- NCT01417754
- Testing
- Toremifene
- Where
- Finland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Satakunta Central Hospital