Clinical trials: Menopause Hot Flashes
Menopause
A Safety and Efficacy Study of the Combination Estradiol and Progesterone to Treat Vasomotor Symptoms
This study will be a prospective, randomized, double-blind, placebo-controlled, parallel group, multicenter trial of postmenopausal subjects with an intact uterus.
- Trial name
- REPLENISH (NCT01942668)
- Testing
- Estradiol, Progesterone
- Where
- 119 sites in United States
- Volunteers
- 1,845 people
- Sponsor
- TherapeuticsMD
Hot Flashes, Climactericum
The Effect of Cold Packs on Hot Flushes and Depression in Women Going Through the Climacteric Period
This study is planned as a pre-post test, randomised controlled, experimental trial designed to determine the effect of applying a cold gel pack to the Sanyinjiao (SP6) and Hegu (Large Intestinal 4 (LI4)) acupoints on hot flushes…
- Conditions
- Hot Flashes, Climactericum, Perimenopausal Depression, Cold Application
- Trial name
- NCT07533097
- Testing
- Cold gel packs application
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Rabia Atilla
Menopause
Effects of a Seven-day BASIS™ Supplementation on Menopausal Syndromes and Measurements of the Urinary Vitamin B3 and Estradiol Levels in Pre-, Peri- and Post-menopause
The purpose of this study is to determine whether a short supplementation (7days) with BASIS™ increases the natural production of estradiol, measured in urinary waste.
- Trial name
- NCT04841499
- Testing
- BASIS™ (Crystalline Nicotinamide Riboside 250mg and Pterostilbene 50mg)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of South Alabama
Hot Flashes, Menopause
Use of Black Cohosh and Red Clover for the Relief of Menopausal Symptoms
This Phase II study, a follow-up to a Phase I trial in normal volunteers, will determine the efficacy of black cohosh and red clover for the relief of menopausal symptoms.
- Trial name
- NCT00066144
- Testing
- Cimicifuga racemosa, Trifolium pratense, Black cohosh
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Hot Flashes
Effect of Dehydroepiandrosterone (DHEA) on Hot Flashes in Postmenopausal Women
The purpose of the study is to evaluate the effect of daily oral intake of DHEA 50 mg for 4 months on reducing vasomotor symptoms (hot flashes) compared to placebo administration in postmenopausal women.
- Trial name
- NCT00317148
- Testing
- DHEA capsule
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Hot Flushes, Vasomotor Symptoms
A Study of MF101 in Postmenopausal Women
This phase 3a study is designed to assess the safety and efficacy of MF101 on the frequency of moderate to severe hot flushes in postmenopausal women.
- Trial name
- HERBA (NCT00906308)
- Testing
- MF101 5 g/day, MF101 10 g/day
- Where
- 50 sites in United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Bionovo
Climacteric Symptoms, Hot Flushes and/or Sweats
Development of Active Safety Surveillance System for Traditional Chinese Medicine
Context:Clinical trials demonstrating increased risk of cardiovascular disease and breast cancer among women randomized to hormone replacement therapy have attracted people's focus on the alternative therapy for menopausal…
- Trial name
- NCT00275964
- Testing
- TMN-1
- Sponsor
- National Taiwan University Hospital
Vasomotor Symptoms Associated With Menopause
Herbal Alternatives for Menopause Symptoms (HALT Study)
Surveys indicate that 25 to 33% of women have moderate to severe menopausal symptoms including hot flashes, night sweats, and disturbed sleep.
- Trial name
- NCT00169299
- Testing
- Black cohosh, Multibotanical preparation, Multibotanical preparation + dietary soy counseling
- Where
- United States
- Volunteers
- 351 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Menopause, Hot Flushes
Alternative Treatments for Menopausal Women
To investigate the reported health benefits (lipid profile, inflammatory factors, cardiovascular status and bone density) of a novel, phytoestrogen rich, Red Clover treatment on women suffering from both menopause related primary…
- Conditions
- Menopause, Hot Flushes, Osteoporosis, Dyslipidemia
- Trial name
- NCT02028702
- Testing
- Red Clover extract
- Where
- Denmark
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Hot Flashes, Menopause
MsFLASH-02: Interventions for Relief of Menopausal Symptoms: A 3-by-2 Factorial Design Examining Yoga, Exercise, and Omega-3 Supplementation
This study is the second clinical trial to be conducted by the Menopause Strategies - Finding Lasting Answers for Symptoms and Health (MsFLASH) research network, a group of investigators conducting clinical trials designed to…
- Conditions
- Hot Flashes, Menopause, Vasomotor Symptoms
- Trial name
- NCT01178892
- Testing
- Omega-3, Yoga, Exercise
- Where
- 3 sites in United States
- Volunteers
- 355 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Postmenopause, Hot Flashes
Comparison of Fluoxetine Versus Citalopram Therapy to Control Postmenopausal Vasomotor Syndrome
This study determined the efficacy of non-hormonal therapy with citalopram compared to fluoxetine, for the treatment of menopausal symptoms in Mexican women with vasomotor syndrome (VMS) and urogenital syndrome.
- Trial name
- NCT05346445
- Testing
- Fluoxetine 20 MG, Citalopram 20mg
- Where
- Mexico
- Volunteers
- 91 people
- Sponsor
- Hospital Regional 1o de Octubre
Hot Flashes, Menopause
Reducing the Experience of Menopausal Symptoms Through Temperature
The purposes of this study are to obtain preliminary evidence on the efficacy of a cooling mattress pad in reducing subjective hot flashes for peri and postmenopausal women experiencing menopausal hot flashes, and to obtain…
- Trial name
- REST (NCT03937466)
- Testing
- Cooling mattress pad
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Wake Forest University Health Sciences
Hot Flashes
Breathe for Hot Flashes Randomized Controlled Trial
Background: Paced respiration has been internationally recommended for vasomotor symptom management despite limited empirical evidence.
- Trial name
- NCT00819182
- Testing
- Paced respiration
- Where
- United States
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- Indiana University
Menopause, Hot Flashes
A Dose-ranging Study of the Efficacy of ESN364 in Postmenopausal Women Suffering Vasomotor Symptoms (Hot Flashes)
This study determined the effects of different doses and dosing regimens of ESN364 on the frequency and severity of hot flashes.
- Trial name
- NCT03192176
- Testing
- Fezolinetant
- Where
- 51 sites in United States
- Volunteers
- 356 people
- Sponsor
- Astellas Pharma Global Development, Inc.
Bipolar Disorder, Major Depressive Disorder
Cognitive Behavioral Group Therapy for the Management of Menopause Symptoms in Mood Disorders
The general objective of this study is to advance insight into non-pharmacological treatments for maturing women that impact psychological health and wellbeing of women adapting to menopause, a natural but often challenging…
- Conditions
- Bipolar Disorder, Major Depressive Disorder, Menopause
- Trial name
- Conklin MWW (NCT02860910)
- Testing
- Cognitive Behavioral Group Therapy
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Danette Conklin, PhD