Clinical trials: Menopause
Postmenopausal Syndrome
Ex Vivo High-Throughput Assay for Vaginal Community Post-menopausal Women
This purpose of this study is to collect vaginal microbial samples of postmenopausal women to assess the optimal conditions for cultivation and storage of the vaginal microbiota.
- Trial name
- FLORA (NCT02415868)
- Where
- Netherlands
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Kimberly-Clark Corporation
Menopause
A Pilot Study to Evaluate Equol and Its Effects on Menopausal Symptoms Experienced by Women in Singapore
The main aim of this study is to evaluate the effect of equol on menopausal symptoms of women. Our hypothesis is that equol producers will have milder menopausal symptoms compared to non-equol producers.
- Trial name
- EQUOL (NCT07136220)
- Testing
- Consumption of soy protein bar
- Where
- Singapore
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ang Seng Bin
Quality of Life, Menopause
Improvement of Quality of Life in Patients Using Low-dose Pills in the Different Phases of Menacme
The purpose of this study is to determine whether low-dose contraceptive pills are effective in the improvement of quality of life in patients in the different phases of menacme.
- Conditions
- Quality of Life, Menopause, Contraception
- Trial name
- NCT01174524
- Testing
- gestoden 60 mcg, ethinylestradiol 15 mcg
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hospital Geral de Fortaleza
Gout
Effect of Aquatic Exercise and Traditional Physical Therapy on Gout in Hypertensive Menopausal Women With Hyperuricemia
Aquatic Exercise and traditional physical therapy are effective methods of treatment for gout and hypertension in menopausal women.
- Trial name
- NCT05454423
- Testing
- the Aquatic exercises +Traditional physical therapy programs +anti-hyperuricemia medication, traditional physical therapy + anti-hyperuricemia medication
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Merit University
Laxity; Skin
Evaluate the Safety and Efficacy of AGE Serum in Post-menopausal Patients on Hormone Replacement Therapy Taking Glucagon-like Peptide-1 Agonist
The primary objective is to assess the safety and efficacy of the AGE Serum in improving the appearance of skin in post-menopausal subjects on HRT and non-HRT who are takingGLP-1 agonist therapy through the use of investigator…
- Trial name
- NCT07558603
- Testing
- On GLP1 plus HRT, On GLP1 Only
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Menopause, Aging
Hormone Replacement and Neural Cardiovascular Control in Postmenopausal Women
Older women have an exaggerated increase in blood pressure during exercise. However, the reasons for this are unclear. It is important to investigate this phenomenon because a greater blood pressure response to exercise has been…
- Conditions
- Menopause, Aging, Blood Pressure
- Trial name
- NCT01633814
- Testing
- Transdermal estradiol
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Menopause, Perimenopause
Effects of a Synbiotic Intervention on Perimenopausal/Menopausal Symptoms
FemmeBiome Meno is a synbiotic supplement, meaning it contains both probiotics (beneficial bacteria) and prebiotics (a special kind of fiber that feeds these bacteria).
- Conditions
- Menopause, Perimenopause, Perimenopausal Women
- Trial name
- NCT07759908
- Testing
- Femmebiome Meno
- Where
- Ireland
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University College Cork
Healthy
Bioavailability Study of Anastrozole Tablets 1 mg of Dr.Reddy's Under Fasting Conditions
The purpose of this study is to compare bioavailability in healthy, post menopausal women subjects under fasting conditions.
- Trial name
- NCT01155947
- Testing
- Anastrozole
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Cardiovascular Diseases, Diabetes
The Flamenco (Fitness League Against MENopause COsts) Project
Spain is the second country in the world that consume more drugs. The average drug expenditure per capita in Andalucía during 2011 was 219.2 €. This drug spending increases during the perimenopausal period.
- Conditions
- Cardiovascular Diseases, Diabetes, Dyslipidemias, Metabolic Syndrome
- Trial name
- FLAMENCO (NCT02358109)
- Testing
- exercise
- Where
- Spain
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Aging, Menopause
Microgreen Consumption for Healthy Aging
Microgreens are an emerging horticultural food crop with potential to improve human health. Previous research suggests they have broad consumer acceptance and that the micronutrient and bioactive compound levels are higher than…
- Conditions
- Aging, Menopause, Healthy
- Trial name
- NCT04239898
- Testing
- Red cabbage microgreens, Red beet microgreens
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Genitourinary Syndrome of Menopause
Continuous Monitoring and Management of Vaginal Health Via Multifunctional OCT/OCTA/OCE Endoscopy
We have recently developed and optimized a vaginal Optical Coherence tomography/angiography endoscopy imaging system. This technology is able to obtain a comprehensive image of the vaginal epithelium, blood vessels, and lamina…
- Trial name
- NCT04737616
- Testing
- CO2 laser, OCT
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Menopause
Effects of the Concentrated Extract of Soy on Coagulation Factors After Menopause
Hypoestrogenism, common in menopause, is responsible for systemic and metabolic changes affecting women's wellness, favoring hot flashes, urogenital atrophy and bone mass loss.
- Trial name
- NCT00925639
- Testing
- Isoflavone
- Where
- Brazil
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Arterial Stiffening, Aging
Sex Hormones and Atherosclerosis Prevention in Perimenopausal Women
The purpose of this study is to find out why women's arteries stiffen as they go through menopause, and how this is affected by estrogen loss.
- Conditions
- Arterial Stiffening, Aging, Menopause
- Trial name
- SHAPE (NCT00608062)
- Testing
- GnRHant - Ganirelix acetate, Transdermal estradiol patch
- Where
- United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Menopause, Pre-menopause
Following Lipectomy to Understand Adipose Tissue Re-accumulation
The typical female pattern of accumulating fat in the hips and thighs has long been thought to confer less risk for disease than the typical male abdominal fat pattern.
- Trial name
- FLARE (NCT00995631)
- Testing
- Femoral lipectomy
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Aromatherapy
The Effect of Aromatherapy to Women With Vasomotor Complaints on Menopausal Quality of Life and Vasomotor Symptoms
Evaluation of the effect of aromatherapy applied to women with vasomotor complaints on menopausal quality of life and vasomotor symptoms.
- Trial name
- Aromatherapy (NCT06035380)
- Testing
- mint oil group, rose oil group
- Where
- Cyprus
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Menopause
Multicentre Clinical Trial. Project EXIMe
Objective: to evaluate the effectiveness of an individualized intervention in sexual health conducted in the midwife consultation to improve the quality of life in women with Genitourinary Syndrome of Menopause.
- Trial name
- EXIMe (NCT03558451)
- Testing
- Complex intervention in sexual health, Usual care
- Where
- Spain
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Gerencia de Atención Primaria, Madrid
Postmenopause
Use of the Synthetic Hormone CDB-2914 in Treating Symptoms of Menopause
This study will examine the safety and effectiveness of a synthetic hormone, CDB-2914, for treating symptoms of menopause. It will compare the effects of estrogen and CDB-2914 with those of estrogen and progesterone in…
- Trial name
- NCT00009659
- Testing
- CDB 2914
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Menopause, Hot Flushes
Alternative Treatments for Menopausal Women
To investigate the reported health benefits (lipid profile, inflammatory factors, cardiovascular status and bone density) of a novel, phytoestrogen rich, Red Clover treatment on women suffering from both menopause related primary…
- Conditions
- Menopause, Hot Flushes, Osteoporosis, Dyslipidemia
- Trial name
- NCT02028702
- Testing
- Red Clover extract
- Where
- Denmark
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Increased Risk for Development of Breast Cancer
Pilot Study of Bazedoxifene Plus Conjugated Estrogen on Imaging and Blood Biomarkers
Pilot study to test feasibility of 6 months of bazedoxifene (BZA) plus conjugated estrogens (CE) to modulate breast MRI parameters.
- Trial name
- NCT04821375
- Testing
- bazedoxifene plus conjugated estrogens
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Carol Fabian, MD
Menopause, Premenopause
MyMenoPlan: Online Resource for Improving Women's Menopause Knowledge and Informed Decision-making
As part of a National Institute on Aging -funded R01, the investigators developed an evidence-based, multi-media digital resource entitled MyMenoPlan to help women learn about the menopause transition, and the symptoms and…
- Conditions
- Menopause, Premenopause, Postmenopause
- Trial name
- NCT05299983
- Testing
- MyMenoPlan, Control
- Where
- United States
- Volunteers
- 410 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego