Clinical trials: Menopause
Gynecological Malignancies, Menopausal Symptoms
An Observational Study of Menopausal Symptom in Patients With Gynecological Malignancy After Oophorectomy
Through long-term dynamic monitoring of gynecologic malignant tumor patients undergoing early menopause after ovaries resection in our center, we explored the changes in menopausal symptoms and bone health status of this…
- Conditions
- Gynecological Malignancies, Menopausal Symptoms, Bone Loss
- Trial name
- NCT06151028
- Testing
- No intervention
- Where
- China
- Volunteers
- 490 people, healthy volunteers welcome
- Sponsor
- Anhui Provincial Hospital
Atrophic Vaginitis, Menopause
Vaginal and Urinary Microbiome Trial
A randomized controlled trial looking at the effects of vaginal estrogen and a nonhormonal alternative on the vaginal and urinary microbiome in women with genitourinary syndrome of menopause.
- Conditions
- Atrophic Vaginitis, Menopause, Recurrent Urinary Tract Infections
- Trial name
- NCT02869165
- Testing
- Conjugated equine estrogen topical cream, Apricot kernel oil
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Postmenopausal Symptoms, Literacy
The Effect of Digital Literacy Education Given to Postmenopausal Women on Health Literacy and Quality of Life
During menopause, women may experience many conditions and symptoms due to fluctuation in hormone levels. These symptoms can affect a woman's social and personal functioning and quality of life.
- Conditions
- Postmenopausal Symptoms, Literacy, Quality of Life, Health Literacy
- Trial name
- NCT05659693
- Testing
- digital literacy education specific to menopause
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Female Androgenetic Alopecia
The Use of 5mg Finasteride Versus 200mg Spironolactone and Topical 5% Minoxidil in Treating Postmenopausal Female Androgenetic Alopecia
The investigators propose to conduct a head-to-head, randomized clinical trial to compare the effectiveness of Minoxidil with Spironolactone and Finasteride in treating postmenopausal females with Androgenetic Alopecia (AGA).
- Trial name
- NCT02483195
- Testing
- 5% Minoxidil, 200mg Spironolactone, 5mg Finasteride
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Gene Expression, Nutrigenomics
The Improving Effects of French Maritime Pine Bark Extract on Antioxidation and Anti-inflammation a in Post-menopausal Women Based on Nutrigenomic Approach
The goal of this clinical trial is to investigate whether French maritime pine bark extract (FMPBE) supplementation can improve antioxidant capacity and reduce inflammation in postmenopausal women aged 40-75 years.
- Trial name
- NCT07855198
- Testing
- French maritime pine bark extract
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Menopause, Hot Flashes
Effect of a Mindfulness-Based Stress Reduction Program on Hot Flashes and Sleep Quality in Menopausal Women: A Randomized Controlled Trial
Menopause is a natural transition characterized by vasomotor symptoms such as hot flashes and sleep disturbances, which can significantly impair quality of life.
- Conditions
- Menopause, Hot Flashes, Sleep Wake Disorders
- Trial name
- MBSR-MENO (NCT07402096)
- Testing
- Mindfulness-Based Stress Reduction (MBSR)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Inonu University
Infertility, Ovarian Failure, Premature
Maturation of Follicles After Transplantation of Ovarian Tissue Into the Pelvic Wall and the Ovary
The purpose of this study is to determine whether the pelvic wall or the ovary represents a better location for the maturation of follicles in the context of ovarian transplantation after cryopreservation of ovarian tissue before…
- Trial name
- Ovartrans (NCT02780791)
- Testing
- Transplantation into pelvic wall, Transplantation into the ovary
- Where
- Switzerland
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Glucose Monitoring, Continuous, Whole Body Protein Metabolism
Effects of Amylopectin Chromium Blend on Whole-Body Protein Kinetics and Glucose in Peri/Post-Menopausal Women
The goal of this study is to better understand how an amylopectin chromium blend may influence whole body protein balance in women during midlife, when hormonal changes can adversely affect protein metabolism and muscle…
- Conditions
- Glucose Monitoring, Continuous, Whole Body Protein Metabolism, Peri-menopausal Women, Post-menopause
- Trial name
- NCT07402382
- Testing
- Amylopectin-chromium blend, Concentrated Amylopectin-chromium blend
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nutrition 21, Inc.
Menopause
RESPeRATE for Treatment of Hot Flashes
This is an uncontrolled pilot clinical trial to determine the feasibility of recruitment and effectiveness of a device called RESPeRATE that paces respiration to treat menopausal hot flashes in 12 peri- or postmenopausal women.
- Trial name
- NCT00283231
- Testing
- Paced Respiration
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Infertility, Polycystic Ovary Syndrome
A New Algorithm to Predict Ovarian Age
To collect data of clinical, biochemical and 3D-ultrasonographic parameters of a population of fertile women aged 18-55 in order to design a new algorithm able to predict ovarian age and to evaluate the reliability of a…
- Conditions
- Infertility, Polycystic Ovary Syndrome, Premature Ovarian Failure (POF), Ovarian Cysts
- Trial name
- OvAge (NCT02086318)
- Testing
- OvAge assessment
- Where
- Italy
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- University Magna Graecia
Menopause, Sexual Desire Disorder
Role of Progesterone in Hypoactive Sexual Desire Disorder in Menopausal Women
The objective of this study is the role of vaginal progesterone gel in the treatment of menopausal hypoactive sexual desire disorder.
- Conditions
- Menopause, Sexual Desire Disorder, Hypoactive Sexual Desire Disorder
- Trial name
- NCT02968342
- Testing
- Vaginal progesterone 8%
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Healthy
Evaluation of Consumption Safety and Effect of Mulberry Leaves and Vietnamese Coriander Based Instant Polyherbal Porridge on Working Memory and Bone Formation Markers
This study the investigators aimed to determine the effect of the herbal porridge containing the combined extract of mulberry and Vietnamese coriander (MP) on cognitive function and bone formation markers of menopausal women.
- Trial name
- NCT02562274
- Testing
- MP 50 mg/day, MP 1500 mg/day
- Where
- Thailand
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
Cardiovascular Disease, Skin Health
Effects of Anthocyanin on Skin Health and Markers of Cardiovascular Disease Risk
The purpose of this study is to determine whether short-term exposure to a compound found in some fruits and vegetables (anthocyanin), is effective in improving skin health and reducing the levels of various markers of…
- Conditions
- Cardiovascular Disease, Skin Health, Postmenopause
- Trial name
- NCT00574574
- Testing
- anthocyanin
- Where
- United Kingdom
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of East Anglia
Postmenopausal Osteoporosis, Gut Microbiota
Blackcurrants Modify Gut Microbiota and Reduce Osteoporosis and CVD Risk
Aim to evaluate the effects of blackcurrant supplementation on changes in gut microbiome, bone mass, and CVD risk factors in adult women.
- Conditions
- Postmenopausal Osteoporosis, Gut Microbiota, Cardiovascular Diseases
- Trial name
- NCT04431960
- Testing
- blackcurrant (BC) extract
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Breast Cancer
Effect of a Natural Health Product on Urinary Estrogen Metabolites
The purpose of this study is to determine if a supplemental formula can beneficially alter the ratio of urinary estrogen metabolites.
- Trial name
- NCT01089049
- Testing
- FemMED Breast Health Formula
- Where
- Canada
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Nutrasource Pharmaceutical and Nutraceutical Services, Inc.
Menopause
Hormone Estradiol Replacement Therapy Additional Herbals
The purpose of this study is to determine whether Hormone Replacement Therapy (HRT), safety studies are combined with herbal (garlic oil, rutin, and nattokinase) to reduce estrogen side effects.
- Trial name
- WH (NCT02618148)
- Testing
- ESTROGEN HERBALS 21, ESTROGEN HERBALS 28
- Where
- Vietnam
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Trieu, Nguyen Thi, M.D.
Cognitive Impairment, Cognitive Function
Brain Health in Breast Cancer Survivors
Endocrine therapy (ET) is widely used to treat hormone receptor positive breast cancer and prevent recurrence by downregulating estrogen function.
- Trial name
- NCT04297020
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Jonsson Comprehensive Cancer Center
Hot Flashes
Effect of Dehydroepiandrosterone (DHEA) on Hot Flashes in Postmenopausal Women
The purpose of the study is to evaluate the effect of daily oral intake of DHEA 50 mg for 4 months on reducing vasomotor symptoms (hot flashes) compared to placebo administration in postmenopausal women.
- Trial name
- NCT00317148
- Testing
- DHEA capsule
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Cervical Cancer Screening, HPV Infections
Cervical Cancer Screening of Postmenopausal Women in Low- and Middle-income Countries Using HPV Self-sampling and Triage by Genotyping and Cytology
Cervical cancer remains a major cause of mortality in low- and middle-income countries, especially among women aged 50 years and older who are often under-screened.
- Conditions
- Cervical Cancer Screening, HPV Infections, Cervical Intraepithelial Neoplasia
- Trial name
- NCT07244315
- Testing
- Vaginal specimens for HPV test will be collected by participants themselves using flocked swabs after explanations by co-investigators.
- Where
- Cameroon
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Meditation, Health Education
Women's Healthy Aging and Menopause; (WHAM)
The present study will examine whether women at high risk for developing hypertension, i.e., post-menopausal status, at least mild psychological distress, and mildly elevated blood pressure, show improvements in these risk…
- Trial name
- NCT07314827
- Testing
- Transcendental Meditation (TM), Women's Health Education (WHE)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Miami