Clinical trials: Menopause
Menopause
The Effects of a Novel Probiotic Supplement on Menopausal Symptoms and Bone Health
This Phase II study is designed to evaluate the potential effects of a novel probiotic supplement on the severity of global menopause symptoms (e.g., psychological, somatic, urogenital symptoms) and on bone health in…
- Trial name
- MPS (NCT04001088)
- Testing
- Probiotic
- Where
- 5 sites in United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Lallemand Health Solutions
Menopause, Perimenopausal Disorder
Effectiveness of Assessment and Educational Intervention on Motor Control of the Pelvic Floor Muscle in Women
The goal of the present study is to evaluate the short and long term effectiveness of a tailored assessment and educational intervention on motor control of the pelvic floor muscle in menopausal and non-menopausal women.
- Trial name
- MENO_edu (NCT03220672)
- Testing
- Tailored assessment and educational
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Malaga
Women in Need of Long Acting Reversibel Cntraception With the Intrauterine Levonorgestrel Releasing System, Mirena
Pretreatment With Mifepristone Prior to Mirena Insertion
Hypothesis: Pretreatment with mifeprsitone prior to Mirena placement will induce amenorrhea and reduce bleeding irrregularities during the initial months of Mirena use.
- Trial name
- MiMi (NCT01931657)
- Testing
- Mifepristone prior to Mirena
- Where
- Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Menopause, Hot Flashes
Acupuncture for Hot Flushes in Menopause
In a pragmatic study investigate whether Traditional Chinese Medicine acupuncture-care decreases the frequency of hot flushes and increases health related quality of life among postmenopausal women.
- Trial name
- ACUFLASH (NCT00284492)
- Testing
- Traditional chinese medicine type acupuncture, Self Care
- Where
- Norway
- Volunteers
- 286 people, healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
Menopause, Perimenopause
Multi-Acupoint Laser Therapy for Body Shape and Composition in Obese Menopausal Women
The purpose of this study is to integrate Traditional Chinese Medicine (TCM) theory and therapeutic methods with modern low-level laser stimulation on corresponding acupoints, applying this combined approach to the field of…
- Conditions
- Menopause, Perimenopause, Obesity, Overweight
- Trial name
- NCT07472881
- Testing
- Multi-acupoint low-level laser therapy, Diet and exercise guidance
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Perimenopausal Depression, Depressive Symptoms
Testing the Efficacy of Mindfulness-based Stress Reduction in the Prevention of Perimenopausal Depression
Depression is the leading cause of disability worldwide and a risk factor for other diseases. While women are at elevated risk for depression in general, the menopause transition is a particularly vulnerable time for many women…
- Trial name
- NCT03526523
- Testing
- Mindfulness-based stress reduction
- Where
- Canada
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Regina
Vaginal Dryness, Menopause
Humectant Activity of a New Formulation of Gynomunal® Vaginalgel
Aim of the study is to evaluate the humectant activity and the local tolerability of a new formulation of Gynomunal® vaginalgel in menopausal women (menopause since at least 2 years) with referred vaginal dryness
- Trial name
- GYNOMUNAL® (NCT01948583)
- Testing
- Hyaluronic Acid
- Where
- Italy
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Derming SRL
Overactive Bladder
Detrol Long Acting (LA) vs Estrace Vaginal Cream for the Treatment of Overactive Bladder Symptoms
The purpose of this study is to determine if long acting tolterodine confers more benefit than intravaginal low dose estrogen in the treatment of Overactive Bladder Syndrome at 12 weeks post-treatment initiation.
- Trial name
- DRIVE (NCT00465894)
- Testing
- Extended Release Tolterodine LA, Intra Vaginal Estradiol Cream
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Aesthetic, Menopause
Post-Menopause Skin Rejuvenation Study
The post-menopausal state is marked by a sharp decline in estrogen, leading to significant structural and functional changes in the skin, including collagen loss, dryness, thinning, and reduced elasticity.
- Conditions
- Aesthetic, Menopause, Post-menopause, Injectables
- Trial name
- NCT07205744
- Testing
- Restylane SkinBoosters Vital, Sculptra Aesthetic
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Erevna Innovations Inc.
Drug Toxicity
Phase I Clinical Study of Soy Isoflavones in Healthy, Post-Menopausal Women
The purpose of this research study is to examine the safety of specific soy components, known as isoflavones, and to find out what effects (good and bad) these components have on tissues that are sensitive to the hormone estrogen…
- Trial name
- NCT00491595
- Testing
- High Dose Soy isoflavones
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of North Carolina
Pelvic Organ Prolapse
Alfacalcidol Supplementation on Levator Ani Muscle Strength of Menopausal Pelvic Organ Prolapse Patients
This is a study performed to evaluate the role of vitamin D supplementation on the strength of levator ani muscle in menopausal women with pelvic organ prolapse
- Trial name
- NCT05505253
- Testing
- Alfacalcidol 0.0005 MG
- Where
- Indonesia
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Universitas Padjadjaran
Menopause, Menopausal Syndrome
Predictors of Religious Orientation Attitudes in Menopausal Women
This descriptive, cross-sectional study examines whether the severity of menopausal symptoms and attitudes toward sexual myths predict intrinsic religious orientation in menopausal women.
- Conditions
- Menopause, Menopausal Syndrome, Sexual Dysfunction
- Trial name
- MENO-RO (NCT07797296)
- Where
- Turkey (Türkiye)
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- KTO Karatay University
Menopause
Hormonal Replacement Therapy and Small Artery Function
Endothelial dysfunction in resistance arteries in women after the menopause is important for the development of high blood pressure and cardiovascular disease
- Trial name
- HRT (NCT00564031)
- Testing
- Femanest, gestapuran, Femanest plus Gestapuran
- Where
- Sweden
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Karolinska University Hospital
Pre-Diabetic
Effect of 1,25-dihydroxyvitamin D3, Treatment on Insulin Secretion and Muscle Strength in Pre-diabetic Persons
The purpose of this research is to study the effects of 1,25(OH)2 D3 (a prescription form of active Vitamin D) on muscle strength and insulin secretion by the pancreas and glucose utilization by skeletal muscle.
- Trial name
- NCT04286529
- Testing
- Calcitriol capsules
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Lipid Depletion, Excessive Physical Exercise, Unspecified
Chinese Health Investigation of Nurse Aging
A follow-up intervention for the climacteric symptoms of nurses in Peking
- Conditions
- Lipid Depletion, Excessive Physical Exercise, Unspecified, Menopausal Syndrome
- Trial name
- NCT02001402
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Bai Wen-Pei
Genitourinary Syndrome of Menopause, Sexual Function Disturbances
The Ultrasonographic Assessment of Efficacy of Injectable Hyaluronic Acid for Genitourinary Syndrome of Menopause
Genitourinary syndrome of menopause (GSM) is a definition including vaginal dryness, burning, vaginal pruritus, dyspareunia and urinary symptoms which can have a negative effect on women's sexuality and quality of life.
- Trial name
- NCT05561972
- Testing
- injectable multifractional intercalated hyaluronic acid [Armonia®, Regenyal, Italy]
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Maltepe University
Genitourinary Syndrome of Menopause
Ultrasonic Evaluation of Carbon Dioxide Laser Effects on Patients With Genitourinary Syndrome
The aim of the study was to evaluate the efficacy of vaginal Carbon Dioxide Laser treatment in patients with Genitourinary Syndrome of Menopause on the improvement of Vulvovaginal Atrophy (VVA) and stress urinary incontinence…
- Trial name
- NCT06142695
- Where
- Italy
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Allergic Rhinitis, Asthma
Integrating Targeted MedlinePlus Health Prescriptions Into Clinic Practice Workflow
The specific aim of this proposed project is to implement a standard process for integrating MedlinePlus health information prescriptions into the clinic workflow.
- Conditions
- Allergic Rhinitis, Asthma, Back Pain, Benign Prostatic Hypertrophy
- Trial name
- NCT00634608
- Testing
- Health Information Prescription
- Where
- United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Vaginal Atrophy, Vulvar Atrophy
VG101 Phase I/II to Treat Vulvar and Vaginal Atrophy in Post-Menopausal Women
To conduct a prospective, randomized, blinded, placebo controlled, dose escalation clinical trial in 4 cohorts of 10 postmenopausal women (total N=40) aged 45 to 65 years with at least one menopausal vaginal symptom, vaginal pH >…
- Trial name
- NCT00453089
- Testing
- VG101
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bionovo
Obesity, Menopause
Calorie Restriction With Leucine Supplementation
The purpose of this study is to determine whether consuming additional leucine during calorie restriction induced weight loss has beneficial or harmful effects on multi-organ (liver, muscle, adipose tissue) insulin sensitivity…
- Conditions
- Obesity, Menopause, Osteoporosis, Sarcopenia
- Trial name
- NCT01757340
- Testing
- Weight loss with normal protein and leucine intake, Weight loss with protein/leucine supplementation
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine