Clinical trials: Menopausal Hot Flashes
Hot Flashes
Mechanical Device for the Relief of Hot Flashes
Hypothesis: A mechanical device when applied to the back of the neck at the onset of a menopausal hot flash will attenuate the severity and duration of symptoms providing women with a reassuring non-hormonal intervention to…
- Trial name
- NCT01281332
- Testing
- Menopod, Inactive device
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Queen's University
Accupuncture, Prostate Cancer
Comparing Acupuncture vs. Sham Acupuncture for the Management of Hot Flashes in Prostate Cancer Patients Receiving Hormone Therapy
This study is evaluating whether acupuncture may help reduce hot flashes in men receiving hormone therapy for prostate cancer. Hot flashes are a common side effect of androgen deprivation therapy (ADT) and may negatively affect…
- Conditions
- Accupuncture, Prostate Cancer, Hormone Therapy, Hot Flashes
- Trial name
- NCT07594002
- Testing
- Real Acupuncture
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Kentucky
Menopause, Hot Flashes
PhytoSERM for Menopausal Hot Flashes and Sustained Brain Health
This is a proof-of-concept phase 2 clinical trial to investigate the effect of the phytoestrogenic supplement PhytoSERM on vasomotor symptoms and other symptoms associated with the menopausal transition, and on blood-based…
- Trial name
- HF-Relief (NCT06186531)
- Testing
- PhytoSERM
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- NeuTherapeutics
Obesity, Menopause Hot Flashes
The Effect of Tirzepatide on Menopausal Vasomotor Symptoms and Biological Aging in Post-menopausal Women With Obesity
The purpose of this study is to determine the effect of tirzepatide on vasomotor symptoms and on measures of biological aging.
- Trial name
- NCT07218445
- Testing
- Tirzepatide
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Menopause
Studying the Impact of Exercise on Hot Flashes
A prospective randomized pragmatic trial will be used to obtain data on energy expenditure, temperature changes and vasomotor symptoms at baseline, during the intervention in which participants will be randomized to either…
- Trial name
- NCT03236896
- Testing
- Exercise, No exercise
- Volunteers
- 35 people
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
PMS, Hot Flashes
A Study to Evaluate the Effects of RCN3028 on Moderate to Severe Vasomotor Symptoms in Women
Hot flashes are the most common symptom of menopause and affect almost 75% of menopausal women. Clinical evidence indicates potent antagonists of 5-HT2A are more likely to cause hypothermia.
- Trial name
- RDC (NCT02100540)
- Testing
- II RDC 0.3mg capsule, III RDC 0.6mg capsule
- Where
- Taiwan
- Volunteers
- 58 people
- Sponsor
- Yung Shin Pharm. Ind. Co., Ltd.
Prostate Cancer, Hot Flashes
Reduce HEAT: A Randomized Trial of Wearable Thermal Devices for ADT-Induced Hot Flashes
This is a prospective, randomized, non-pharmacologic interventional trial evaluating the effectiveness of the Embr Wave wearable thermal device in reducing hot flash burden in men with prostate cancer receiving androgen…
- Conditions
- Prostate Cancer, Hot Flashes, Vasomotor Symptoms
- Trial name
- ReduceHEAT (NCT07729150)
- Testing
- Embr Wave
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Dana-Farber Cancer Institute
Menopause, Hot Flashes
Caria: Digital Intervention for Menopause Symptom
Menopause is the time of life when menstrual cycles cease. Women typically spend 30-40% of their lives in menopause. Individual experiences of menopause vary and although some women do not experience any significant symptoms…
- Trial name
- NCT04882982
- Testing
- Caria app, Menopause Education
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Illinois at Chicago
Hot Flashes
A Study to Evaluate the Effects of RAD1901 in the Treatment of Vasomotor Symptoms in Postmenopausal Women
The purpose of this study is to determine whether RAD1901 is effective in decreasing hot flashes in postmenopausal women.
- Trial name
- NCT00875420
- Testing
- RAD1901
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Radius Pharmaceuticals, Inc.
Hot Flashes, Breast Cancer
Evaluate RCN3028 in Treatment of Drug-Induced VMS in Breast Cancer
Due to the fact that majority of breast cancers are estrogen-receptor and/or progesterone receptor positive, tamoxifen and aromatase inhibitors (AIs) are among the mainstay therapies to treat breast cancer.
- Trial name
- VMS (NCT06161792)
- Testing
- 0.8 mg RCN3028
- Where
- 4 sites in Taiwan
- Volunteers
- 10 people
- Sponsor
- Yung Shin Pharm. Ind. Co., Ltd.
Menopause, Hot Flashes
Alternative Therapies for Menopause: A Randomized Trial
This randomized, controlled trial will evaluate the efficacy and safety of three alternative approaches utilizing phytoestrogens to treat hot flashes and night sweats in peri- and post-menopausal women.
- Trial name
- NCT00061711
- Testing
- Hormone Replacement Therapy, Cimicifuga racemosa (Black Cohosh), Multibotanical phytoestrogen formula
- Where
- United States
- Volunteers
- 355 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Menopausal Symptoms
Effects of Soy Isoflavones on Menopausal Hot Flashes
Hot flashes occur in three quarters of menopausal women, and can negatively impact quality of life. Interest has arisen in isoflavones, found in rich supply in soy products, as therapy for hot flashes.
- Trial name
- NCT00179556
- Testing
- Isoflavone supplement
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Breast Cancer, Depression
Tamoxifen in Women With Breast Cancer and in Women at High-Risk of Breast Cancer Who Are Receiving Venlafaxine, Citalopram, Escitalopram, Gabapentin, or Sertraline
RATIONALE: Studying samples of blood in the laboratory from patients receiving tamoxifen may help doctors learn more about the effects of other drugs on the level of tamoxifen in the blood.
- Conditions
- Breast Cancer, Depression, Hot Flashes, Psychosocial Effects of Cancer and Its Treatment
- Trial name
- NCT00667121
- Testing
- citalopram hydrobromide, escitalopram oxalate, gabapentin
- Where
- 6 sites in United States
- Volunteers
- 88 people
- Sponsor
- Mayo Clinic
Breast Cancer
Acupuncture for Hot Flashes in Hormone Receptor-Positive Breast Cancer, a Randomized Controlled Trial
This research study is evaluating acupuncture, a medical therapy in which hair-thin, stainless steel needles are shallowly inserted into specific points to help the body's natural healing process, as a possible treatment to…
- Trial name
- NCT03783546
- Testing
- Acupuncture, Usual Care
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Dana-Farber Cancer Institute
Hot Flashes
24-Week Efficacy & Safety Study of Brisdelle™ (Formerly Known as Mesafem) in the Treatment of Vasomotor Symptoms
To assess the safety and efficacy of Brisdelle (paroxetine mesylate) Capsules 7.5 mg for treatment of vasomotor symptoms (VMS) associated with menopause
- Trial name
- NCT01101841
- Testing
- Brisdelle (paroxetine mesylate)
- Where
- 32 sites in United States
- Volunteers
- 570 people
- Sponsor
- Noven Therapeutics
Menopause-related Hot Flashes
Yoga for Treatment of Hot Flashes
The Yoga for Treatment of Hot Flashes and Menopausal Symptoms is an uncontrolled pilot clinical trial to determine the feasibility of recruitment and of evaluating yoga for the relief of menopausal hot flashes in 12 peri- or…
- Trial name
- NCT00283205
- Testing
- Yoga
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Menopausal Symptom Relief
"Pi" and Hot Flushes
Hot flushes are common symptoms in women after menopause, and are important causes of discomfort and lead to high number of medical consultations.
- Trial name
- NCT01315041
- Testing
- Capsicum frutescens fruits, homeopathic medicine, Inert alcoholic solution
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Casa Espirita Terra de Ismael
Hot Flashes
Effect of High Power Laser Acupuncture on Post Menopausal Hot Flashes
The aim of this study will be to determine the effect of high power laser acupuncture on post menopausal hot flashes.
- Trial name
- NCT07419542
- Testing
- High power laser acupuncture, Paced Respiration Exercise
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men, Hot Flashes
A Study to Learn How Safe the Study Treatment Elinzanetant is and How it Moves Into, Through and Out of the Body When Given as Single Increasing Doses That Are Higher Than Normally Used Compared to Placebo and Moxifloxacin in Healthy Participants
Researchers are looking for a better way to treat vasomotor symptoms, a condition of having hot flashes. The condition is caused by hormonal changes and occurs primarily in women, but can also affect men.
- Conditions
- Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men, Hot Flashes, Healthy Volunteers
- Trial name
- NCT05481528
- Testing
- Moxifloxacin, Elinzanetant (BAY3427080)
- Where
- Germany
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Bayer
Menopause, Prediabetes
Effects of Novel Estrogens on Glucose and Lipids in Postmenopausal Prediabetic Women Veterans
The purpose of this study is to determine the effect of a novel menopause hormone therapy on blood sugar (glucose) and blood and liver fats (lipids) in obese menopausal women Veterans.
- Conditions
- Menopause, Prediabetes, Obesity
- Trial name
- CE/BZA (NCT05073237)
- Testing
- conjugated estrogens/bazedoxifene (CE/BZA)
- Where
- United States
- Sponsor
- VA Office of Research and Development