Clinical trials: Meniscal Tear
Meniscal Tears
Meniscal Repair Augmented With Leukocyte-Poor Platelet-Rich Plasma: A Prospective Comparative Clinical Study
This prospective, randomized, comparative clinical study will evaluate the clinical and functional outcomes of meniscal repair augmented with intraoperative intralesional leukocyte-poor platelet-rich plasma (LP-PRP) compared with…
- Trial name
- NCT07815743
- Testing
- Leukocyte-poor platelet-rich plasma, Meniscal Repair
- Where
- Mexico
- Volunteers
- 62 people
- Sponsor
- Universidad Autonoma de Nuevo Leon
Meniscus Tear, Meniscus; Derangement
Enhancing Recovery Through a Combined Mechanobiologic Intervention Following Meniscus Repair
Arthroscopic meniscal procedures are the most commonly performed orthopaedic procedure in the U.S. affecting 15% of Americans ages 10-65 years.
- Conditions
- Meniscus Tear, Meniscus; Derangement, Meniscus Lesion, Meniscus Disorder
- Trial name
- NCT05505747
- Testing
- Fisetin
- Where
- United States
- Sponsor
- Austin V Stone
Meniscus Tear, Meniscus Disorder
Clinical Outcomes, Graft Longevity, and Chondral Protection Following Primary or Revision Meniscal Allograft Transplantation Surgery
The MERCuRE (MEniscus, REstoration, Conservation, and Repair) group is embarking on a 20-year follow-up study to evaluate the clinical outcomes, graft longevity, and chondral protection following primary or revision Meniscal…
- Conditions
- Meniscus Tear, Meniscus Disorder, Patient Satisfaction
- Trial name
- NCT06749431
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Joint Restoration Foundation, Inc.
Meniscus Injury, Meniscus Tear
Assessment of Quadriceps Femoris Muscle Function in Patients After Arthroscopic Knee Surgery in Outpatient Rehabilitation
The goal of this clinical trial is to learn if a high intensity magnetic field is an effective way to treat quadriceps muscle atrophy after knee arthroscopic surgery in adult patients.
- Conditions
- Meniscus Injury, Meniscus Tear, Arthroscopic Knee Surgeries, ACL Injuries
- Trial name
- NCT06870825
- Testing
- High-intensity Magnetic Field Muscle Stimulation, Transcutaneous Neuromuscular Electrical Stimulation
- Where
- Lithuania
- Volunteers
- 150 people
- Sponsor
- Lithuanian University of Health Sciences
Meniscus Tear
Effects of TENS Therapy Following Arthroscopic Knee Surgery
Following standard of care procedures for arthroscopy knee surgery it is anticipated that Transcutaneous Electrical Nerve Stimulation (TENS) will provide improved pain relief and improve functional outcomes.
- Trial name
- TENS (NCT01528228)
- Testing
- TENS Treatment with functional or disabled unit
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- A.T. Still University of Health Sciences
ACL Reconstruction, Meniscus Tears
A Comparison of Outcomes After Anterior Cruciate Ligament (ACL) or Anterior Cruciate Ligament and Meniscus (ACL+Meniscus) Surgery Using Semiconductor Fabric Products
The goal of this clinical trial is to determine the effect of semiconductor sleeves on the treatment of Anterior Cruciate Ligament (ACL) or Anterior Cruciate Ligament and Meniscus (ACL+Meniscus) arthroscopic surgery.
- Conditions
- ACL Reconstruction, Meniscus Tears, Anterior Cruciate Ligament Rupture
- Trial name
- NCT06979804
- Testing
- Semiconducting fabric sleeves, Non-semiconducting fabric sleeves
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- Illinois Center for Orthopaedic Research and Education
Meniscal Tear, Meniscus Tear
Study of Suture Repair of Torn Meniscus in the Knee
Horizontal meniscus tears meeting specified criteria will be repaired by any commonly used suture technique. Subjects will be followed for 2 years to evaluate the effectiveness of the repair, by assessing the re-operation rate…
- Trial name
- STITCH (NCT02237001)
- Testing
- Suture-based meniscal repair
- Where
- 8 sites in United States
- Volunteers
- 30 people
- Sponsor
- Smith & Nephew, Inc.
Knee Pain Chronic
Arthroscopic Versus Conservative Treatment of Degenerative Meniscal Tear in Middle Aged Patients in Regard to Pain & Knee Function
The study is prospective comparative study, conducted in Erbil teaching hospital on 60 patients, their age ranging between 40 and 60 years.
- Trial name
- NCT04313569
- Testing
- Arthroscopic menisctomy
- Where
- Iraq
- Volunteers
- 60 people
- Sponsor
- Hawler Medical University
Knee Medial Meniscus Tears, Meniscus Lesion
Predictors of Early Success From Circumferential Compression STITCH Meniscal Repairs
This is a retrospective study of meniscal tear repairs at least one-year post repair status. All patients were treated with Ceterix NovoStitch devices.
- Conditions
- Knee Medial Meniscus Tears, Meniscus Lesion, Meniscus; Rupture, Bucket Handle, Meniscus Disorder
- Trial name
- STITCHRetro (NCT03097744)
- Testing
- Ceterix NovoStitch
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Smith & Nephew, Inc.
Anterior Cruciate Ligament Tear, Knee Meniscus Tear
Adductor Canal Block Versus Femoral Block on Pain and Quadriceps Strength
The purpose of this study is to compare the effects of a femoral nerve block vs. an adductor canal block on pain and quadriceps muscle strength for knee arthroscopy surgery.
- Trial name
- NCT05190120
- Testing
- Femoral Nerve Block, Adductor Canal Nerve Block, preoperative Femoral Nerve Block using 20ml of 0.5% ropivacaine
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- University of California, San Francisco
Meniscal Tear
Safety and Efficacy of OMS103HP-S Administered in Joint Irrigation Solution to Subjects Undergoing Arthroscopic Meniscectomy
The purpose of this study is to assess the effect of OMS103HP solution for Injection (OMS103HP-S) and function as measured by the Knee Osteoarthritis Outcome Survey (KOOS) Symptoms subscale through Day 30 compared with vehicle…
- Trial name
- NCT01406561
- Testing
- OMS103HP-S, Vehicle
- Where
- 18 sites in United States
- Volunteers
- 344 people
- Sponsor
- Omeros Corporation
Knee; Injury, Meniscus (Lateral) (Medial), Meniscus Tear
Clinical Efficacy of Exosome in Degenerative Meniscal Injury
Comparison of intra-articular administration of synovial fluid-derived mesenchymal stem cells-derived exosomes with synovial fluid-derived mesenchymal stem cells on the same patient.
- Conditions
- Knee; Injury, Meniscus (Lateral) (Medial), Meniscus Tear, Meniscus Lesion, Meniscus; Degeneration
- Trial name
- KNEEXO (NCT05261360)
- Testing
- SF-MSC-EX, SF-MSC
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Eskisehir Osmangazi University
Meniscus Tear
Prospective Trial of Arthroscopic Meniscectomy for Degenerative Meniscus Tears
Arthroscopic meniscectomy is among the most commonly performed orthopedic surgical procedures in the VA system. There remains substantial uncertainty, however, regarding the short term benefits and the long term consequences of…
- Trial name
- NCT01931735
- Testing
- Randomized Meniscectomy, Randomized Lavage, Standard of Care Meniscectomy Pre-Amend
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- VA Office of Research and Development
Patient Satisfaction, Graft Failure
Semitendinosus Graft as Meniscal Transplant
Removal of meniscal tissue is described to result in poor knee function and a significant risk for future development of osteoarthritis. Different implants have been suggested to substitute a removed meniscus.
- Conditions
- Patient Satisfaction, Graft Failure, Osteo Arthritis Knee, ACL
- Trial name
- NCT04753424
- Testing
- Surgical technique
- Where
- Sweden
- Volunteers
- 10 people
- Sponsor
- Karolinska Institutet
Meniscus Tear, Tibial, Osteoarthritis, Knee
Arthroscopic Partial Meniscectomy Versus Exercise Therapy for Meniscal Injuries in Older Patients, a 5 Year Follow up.
Arthroscopic partial meniscectomie (APM) offers little short-term to medium-term benefit above sham surgery or non-surgical management for knee function in most patients with a symptomatic degenerative meniscus tear.
- Trial name
- NCT05068843
- Testing
- arthroscopic partial meniscectomy, Physical therapy
- Volunteers
- 321 people
- Sponsor
- Onze Lieve Vrouwe Gasthuis
ACL Injury, Meniscus Tear
MOntelukast as a Potential CHondroprotective Treatment Following Anterior Cruciate Ligament Reconstruction (MOCHA Trial)
This is a multicenter randomized, placebo-controlled trial to assess whether a 6-month course of oral montelukast after ACL reconstruction reduces systemic markers of inflammation and biochemical and imaging biomarkers of…
- Conditions
- ACL Injury, Meniscus Tear, Post-traumatic Osteoarthritis
- Trial name
- MOCHA (NCT04572256)
- Testing
- Montelukast
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Austin V Stone
Knee Injuries, Shoulder Injuries
Internet Enhanced, Patient-Centered Orthopedic Care: A Prospective, Randomized, Controlled Pilot Trial
The investigators have previously reported on patient utilization of an eRehab patient education web portal that utilizes streaming, clinician prescribed video instruction to motivate and inform patients in self-care of their…
- Conditions
- Knee Injuries, Shoulder Injuries, Rotator Cuff Disease, Meniscus Tear
- Trial name
- NCT02025400
- Testing
- eRehab, Formal Physical Therapy
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Charlotte Sports Medicine Institute, PA
Meniscus Tear
Study to Evaluate the Safety and Efficacy of AM3101 to Augment Meniscal Healing
The purpose of this clinical trial is to assess the safety and efficacy of AM3101 to facilitate meniscal repair and reduce the incidence of non-healing complications and morbidities associated with a failed meniscal repair.
- Trial name
- NCT05560477
- Testing
- AM3101
- Where
- 3 sites in United States
- Volunteers
- 22 people
- Sponsor
- University of Cincinnati
Meniscus Tear Caused by a Traumatic Event, Fibrin Clot Augmentation
A Comparative Prospective Study of the Arthroscopic Meniscal Repair Methods
Performing arthroscopic meniscus repair following a traumatic meniscus tear as an alternative to a meniscectomy is now an acceptable choice.
- Conditions
- Meniscus Tear Caused by a Traumatic Event, Fibrin Clot Augmentation, Meniscal Repair
- Trial name
- NCT06176183
- Testing
- Arthroscopic meniscus repair
- Where
- 2 sites in Lithuania
- Volunteers
- 100 people
- Sponsor
- Vilnius University
Meniscus Tear
Outcomes of the Nanoscopic Partial Meniscectomy Versus Standard Arthroscopic Partial Meniscectomy
Standard arthroscopy has been the gold standard for treatment of meniscus tears since the 1980's. The purpose of this study is to analyze the clinical outcomes of using the smaller diameter Nanoscope for partial menisectomy.
- Trial name
- NCT05617807
- Testing
- Nanoscopic partial meniscectomy, Standard Partial Meniscectomy
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Marshall University