Clinical trials: Meniscal Tear
Meniscus Injury
Efficacy and Safety of FF-31501 in Meniscus Tear Patients
A single-arm, multi-center study to verify that knee joint function at 52 weeks after injection of FF-31501 is better than at screening in patients with meniscus tear who are eligible for meniscectomy .
- Trial name
- NCT05777967
- Testing
- human autologous synovial stem cells
- Where
- 4 sites in Japan
- Volunteers
- 18 people
- Sponsor
- FUJIFILM Toyama Chemical Co., Ltd.
Rupture; Meniscus, Bucket Handle
Can a Simple Trephination Increase the Heeling Potential for All-inside Meniscal Repair in the Vascular Zone?
Meniscus does not always heal when sutured. The investigators will make small holes in the meniscus before repair to promote more bleeding. The investigators expect that will help the meniscus to heal better.
- Trial name
- NCT01740232
- Testing
- trephination, Normal meniscal repair
- Where
- 2 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Mikkel Lindegaard Attrup
Degenerative Meniscus Tear
The Benefit of Arthroscopic Partial Meniscectomy in Middle-Aged Patients
BACKGROUND Osteoarthritis (OA) is the most common form of arthritis and the knee is one of the most affected joints. The meniscus plays an important role in the development of knee OA.
- Trial name
- SLAMSHAM (NCT01264991)
- Testing
- Arthroscopic partial meniscectomy
- Where
- 2 sites in Denmark
- Volunteers
- 41 people
- Sponsor
- Slagelse Hospital
Meniscus Tear, Meniscus Lesion
Study of Clinical Performance and Safety of Treatments in Degenerative Meniscopathy With Injection of Polynucleotides
This is a non-randomized multicentre study for the evaluation of the clinical performance and safaty of the augmentation-to-surgery and conservative treatments for the degenerative meniscopathies, with injection of polynucleotide…
- Trial name
- NCT05322005
- Testing
- partial meniscectomy, Condrotide® (polynucleotides gel: class III medical device)
- Where
- 2 sites in Belgium, Italy
- Volunteers
- 60 people
- Sponsor
- Mastelli S.r.l
Degenerative Meniscal Tear
Surgical or Exercise Therapy on Patients With Degenerative Meniscus Tears
This study is conducted as a collaboration between NAR, Orthopedic Department, Oslo University Hospital,Ullevaal, Hjelp24Nimi Oslo, Martina Hansens Hospital Norway, and University of Southern Denmark, Odense, Denmark.
- Trial name
- OMEX (NCT01002794)
- Testing
- Arthroscopic partial menisectomy, Supervised neuromuscular and strength training
- Where
- Norway
- Volunteers
- 140 people
- Sponsor
- Oslo University Hospital
Degenerative Disease, Meniscus Tear
The Open Kinetic Chain and Closed Kinetic Chain Strengthening Exercises in Degenerative Meniscus Tears
This randomized-controlled trial aims to compare the effect of open kinetic chain and closed kinetic chain strengthening exercises on pain, function, and health-related quality of life in degenerative meniscus tears.
- Conditions
- Degenerative Disease, Meniscus Tear, Knee Pain Swelling
- Trial name
- NCT06447142
- Testing
- Open kinetic chain strengthening exercise, Closed kinetic chain strengthening exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Istanbul University - Cerrahpasa
Meniscus Tear
Safety and Performance Study of the FAST-FIX FLEX System for Meniscal Repairs and Meniscal Transplantations
This study is a post-market follow-up study (PMCF). The data collected will serve the purpose of confirming the safety and performance of the FAST-FIX FLEX device, used according to the indicated for use (IFU) for meniscal repair…
- Trial name
- FAST-FIX FLEX (NCT04903106)
- Testing
- FAST-FIX FLEX Meniscal Repair System
- Where
- 5 sites in United States, Australia and 2 more
- Volunteers
- 63 people
- Sponsor
- Smith & Nephew, Inc.
Meniscal Degeneration, Osteoarthritis, Knee
Comparing Different Types of Physical Therapy for Treating People With a Meniscal Tear and Osteoarthritis
Knee osteoarthritis is a disabling problem affecting over 15 million adults in the United States. Many people who have knee arthritis also experience painful meniscal tears.
- Trial name
- TeMPO (NCT03059004)
- Testing
- TeMPO Home Exercise Program, Motivational SMS Messages, In-Clinic Topical Therapy
- Where
- 4 sites in United States
- Volunteers
- 879 people
- Sponsor
- Brigham and Women's Hospital
Knee Arthroscopy Surgery, Knee Acute and Chronic Pain
Arthroscopic Infrapatellar Fat Pad Release and Mesenchymal Stem Cell Mobilization
This prospective, single-center, paired-sample clinical laboratory study evaluated whether controlled mechanical release of the infrapatellar fat pad during knee arthroscopy increases the number of intra-articular cells with a…
- Conditions
- Knee Arthroscopy Surgery, Knee Acute and Chronic Pain, Meniscal Tears
- Trial name
- IP-MSC-RELEASE (NCT07736716)
- Testing
- Controlled Mechanical Release of the Infrapatellar Fat Pad
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Ankara City Hospital Bilkent
Meniscus Lesion, Meniscus Tear
Long-term Follow-up of Actifit® Meniscal Scaffold Patients.
This study will collect retrospective patient data of Actifit patients (medial and lateral, isolated cases as well as cases with concomitant procedures), including pre-op and any post-op imaging, for 120 retrospective Actifit…
- Trial name
- NCT07800923
- Where
- Belgium
- Volunteers
- 120 people
- Sponsor
- Orteq Sports Medicine
Meniscus Disorder, Meniscus, Torn Tibial
Blood Flow Restriction After Meniscus Repair
The purpose of this study is to evaluate post-operative outcomes after meniscus surgery in participants undergoing blood flow restriction training as a rehabilitative adjunct compared to those with standard rehabilitation.
- Conditions
- Meniscus Disorder, Meniscus, Torn Tibial, Meniscus Lesion, Meniscus Tear, Tibial
- Trial name
- NCT04436523
- Testing
- Blood flow restriction (Delfi Personalized Tourniquet System), Standard rehabilitation
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of California, San Francisco
Meniscal Injuries, Meniscal Tear
Semitendinosus Autograft vs Meniscal Allograft in Post-Meniscectomy Syndrome
This multicenter, stratified, partially randomized clinical trial aims to compare autologous semitendinosus tendon graft and meniscal allograft transplantation (MAT) in young adults with post-meniscectomy syndrome.
- Conditions
- Meniscal Injuries, Meniscal Tear, Meniscus Lesion
- Trial name
- MAT (NCT07204587)
- Testing
- Autologous Semitendinosus Tendon Graft, Meniscal Allograft Transplantation (MAT)
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Chang Gung Memorial Hospital
ACL Injury
Multimodal Assessment of Knee Conditions in Rehabilitation
The purpose of this study is to assess ACL injury and other pathological knee conditions from the combination of signals that are known to provide information on the knee joint.
- Trial name
- NCT03608189
- Where
- Finland
- Volunteers
- 20 people
- Sponsor
- University of Oulu
Anterior Cruciate Ligament Injuries
How to Best Treat Anterior Cruciate Ligament Injuries
The project is a pragmatic registry-based RCT aiming to investigate ACL injury treatment. Study results will help fill knowledge gaps, facilitate shared decision making and strengthen patient treatment.
- Trial name
- NCT04770233
- Testing
- Early ACL reconstruction, Active rehabilitation
- Where
- 2 sites in Norway
- Volunteers
- 328 people
- Sponsor
- University Hospital, Akershus
Meniscal Tears, ACL - Anterior Cruciate Ligament Rupture
The Clinical Study of Bone-patellar Tendon-bone and Quasi-anatomical Meniscus Allograft Transplantation Technique
This clinical study investigates the outcomes of bone-patellar tendon-bone and quasi-anatomical meniscus allograft transplantation techniques in patients requiring joint reconstruction.
- Trial name
- BPTB，Meniscus (NCT07088094)
- Testing
- bone-patellar tendon-bone or meniscus allograft transplantation techniques, Quasi-anatomical meniscus allograft transplantation
- Volunteers
- 200 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Meniscus Tear, Tibial
Operative vs Non-operative Management of Posterior-medial Meniscal Root Tears: A Randomized Multicenter Trial (RCT)
The purpose of this study is to determine differences in pain, functional patient reported outcomes, and objective imaging parameters following non-operative and meniscus root repair treatment.
- Trial name
- NCT05985772
- Testing
- Non-Operative Pain Management, Operative treatment arm will undergo transtibial medial meniscus root repair within 3 weeks of enrollment
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Rush University Medical Center
Meniscus Tear, Tibial, Pain, Postoperative
Ketorolac as an Adjuvant Agent for Postoperative Pain Control Following Arthroscopic Meniscus Surgery
The utilization of arthroscopic surgery to treat meniscus injuries has continued to increase in recent years, partly due to a younger, more active population, and improved technology and technique.
- Conditions
- Meniscus Tear, Tibial, Pain, Postoperative, Postoperative Complications, Ketorolac Adverse Reaction
- Trial name
- NCT04246541
- Testing
- Ketorolac, Oxycodone-Acetaminophen
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Meniscus Tear, Chondropathy/Degenerative Joint Disease (DJD)
Post-op Treatment With Hyaluronic Acid Injections
This study will look at patients with post-operative treatment of a meniscal tear or degenerative joint disease (degenerative arthritis).
- Trial name
- NCT01256788
- Testing
- Euflexxa, Saline
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- The Hawkins Foundation
Meniscus Tear
Early Arthroscopic Partial Meniscectomy(APM)
Arthroscopic partial meniscectomy(APM) surgery outcomes for Metabolic Syndrome(MetS) patients with degenerative meniscus tears(DMTs) was still not clear.
- Trial name
- NCT05114694
- Testing
- early APM, delayed APM
- Where
- China
- Volunteers
- 120 people
- Sponsor
- The First People's Hospital of Jingzhou
Platelet-Rich Plasma, Meniscus Lesion
Platelet-rich Plasma for Menical Tear
Meniscal injuries are a common pathology among athletes, and have an impact on the daily or sporting practice of patients. Surgical approach implies sometimes heavy consequences.
- Trial name
- NCT04040283
- Testing
- Platelet-rich plasma (PRP) therapy
- Where
- Spain
- Volunteers
- 15 people
- Sponsor
- University of Malaga