Clinical trials: Memory Deficit
Cannabis Intoxication
The Impact and Detection of Driving Impairments Associated With Acute Cannabis Smoking
This study was authorized by the California Legislature (Assembly Bill 266, the Medical Marijuana Regulation and Safety Act to help with detection of driving under the influence of cannabis.
- Trial name
- NCT02849587
- Testing
- Cannabis
- Where
- United States
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Mild Cognitive Impairment (MCI), Mild Alzheimer Disease
Self-Administered Interactive Exercise Program (Tele-Exergame)
This longitudinal Phase I feasibility trial combines care-as-usual with a 6-week, single-arm exercise intervention using Tele-Exergame, an interactive, self-administered home-based exercise program aimed at improving…
- Conditions
- Mild Cognitive Impairment (MCI), Mild Alzheimer Disease, Memory Deficits
- Trial name
- NCT07072962
- Testing
- home-based self-administered interactive exercise
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Baylor College of Medicine
Alzheimer's Disease, Vascular Dementia
Effect of Insulin Sensitizer Metformin on AD Biomarkers
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive loss of memory and other cognitive functions.
- Conditions
- Alzheimer's Disease, Vascular Dementia, Dementia, Memory Impairment
- Trial name
- NCT01965756
- Testing
- Metformin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Pennsylvania
TBI (Traumatic Brain Injury), Brain Injuries
Brain Markers of Improvements in Cognitive Functioning
Some of the most common, persistent, and disabling consequences of traumatic brain injury affect an individual's ability to achieve personal goals.
- Conditions
- TBI (Traumatic Brain Injury), Brain Injuries, Stress, Attention Deficit
- Trial name
- NCT03490110
- Testing
- State regulation skill training, Treatment-as-usual
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- VA Office of Research and Development
Memory Impairment
Reversing Corticosteroid Induced Memory Impairment
Medically stable outpatients receiving chronic oral corticosteroid therapy were enrolled in a 48-week randomized, double-blind, placebo-controlled, parallel-group, trial of lamotrigine.
- Trial name
- NCT01142310
- Testing
- Lamotrigine
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of Texas Southwestern Medical Center
Alzheimer Disease
tACS for Amyloid-β Reduction in Alzheimer's Disease
Alzheimer's Disease (AD) is characterized by amyloid-β (Aβ) plaque buildup and phosphorylated tau (p-tau) in the brain, as well as widespread neurodegeneration.
- Trial name
- NCT03290326
- Testing
- Transcranial Alternating Current Stimulation (tACS)
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Massachusetts General Hospital
Mild Cognitive Impairment, Alzheimer's Disease
Reducing Risk for Alzheimer's Disease in High-Risk Women Through Yogic Meditation Training
The purpose of this pilot study will be to test whether Kundalini yoga (KY) and Kirtan Kriya (KK) yogic meditation is superior to Memory Enhancement Training (MET) for improving cognitive functioning, health (including…
- Trial name
- NCT03503669
- Testing
- Memory Training, Kundalini yoga and meditation
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, Los Angeles
Mild Cognitive Impairment
Olfactory Deficits in MCI as Predictor of Improved Cognition on Donepezil
Odor identification deficits, which are a result of early Alzheimer's Disease (AD) pathology in the olfactory bulb and tract as well as olfactory projection areas in the medial temporal lobe (entorhinal and piriform cortex and…
- Trial name
- NCT01845636
- Testing
- Donepezil, Atropine
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- New York State Psychiatric Institute
Memory Impairment, Alzheimer's Disease
Roflumilast and Donepezil to Reverse Scopolamine Induced Cognitive Deficits in Healthy Adults
The purpose of this study is to determine whether scopolamine-induced cognitive impairment is attenuated by the administration of roflumilast in combination with donepezil.
- Trial name
- NCT02051335
- Testing
- Roflumilast, Donepezil, Scopolamine
- Where
- United Kingdom
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Mild Cognitive Impairment, Dementia
A 3 Year Study to Evaluate the Safety and Efficacy of Low Dose Ladostigil in Patients With Mild Cognitive Impairment
The purpose of this study is to determine whether treatment with the investigational drug ladostigil will delay the onset of Alzheimer's disease(AD) in patients with Mild Cognitive Impairment (MCI).
- Trial name
- NCT01429623
- Testing
- ladostigil hemitartrate
- Where
- 12 sites in Austria, Germany and 1 more
- Volunteers
- 210 people
- Sponsor
- Avraham Pharmaceuticals Ltd
Mild Cognitive Impairment, Cognitive Decline
Exercise in Adults With Mild Memory Problems
This study evaluates the effects of physical exercise on cognition, functional status, brain atrophy and blood flow, and cerebrospinal fluid biomarkers of Alzheimer's disease in adults with a mild memory impairment.
- Conditions
- Mild Cognitive Impairment, Cognitive Decline, Memory Impairment
- Trial name
- EXERT (NCT02814526)
- Testing
- Aerobic exercise, Stretching/balance/range of motion exercise
- Where
- 14 sites in United States
- Volunteers
- 296 people
- Sponsor
- Alzheimer's Disease Cooperative Study (ADCS)
Dementia, Alzheimer Disease
Our Care Wishes - Dementia
This Our Care Wishes- Dementia pilot study is adapting an existing successful online advance care planning platform to the specific needs of persons living with dementia and shared decision-makers (SDMs) and testing the usability…
- Conditions
- Dementia, Alzheimer Disease, Memory Impairment
- Trial name
- NCT05033262
- Testing
- Our Memory Care Wishes
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Alzheimer's Disease
Trial of Carvedilol in Alzheimer's Disease
This is a 6-month pilot randomized double-blind placebo-controlled trial of carvedilol, with the primary objective being to determine whether carvedilol treatment is associated with improvement in Alzheimer's Disease (AD) as…
- Trial name
- NCT01354444
- Testing
- Carvedilol
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Johns Hopkins University
Mild Cognitive Impairment
Memory Training Versus Yogic Meditation Training in Older Adults With Mild Cognitive Impairment
The purpose of this pilot study is to test whether 6 months of supervised weekly Kundalini yoga classes and a brief daily meditation homework assignment can improve memory and thinking in older adults with mild memory complaints…
- Trial name
- NCT01983930
- Testing
- Kundalini yoga and meditation, Memory Training
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- University of California, Los Angeles
Traumatic Brain Injury
Brain Training to Enhance Frontal Lobe Reasoning
This study is being done to improve the ability to diagnose and to achieve higher-levels of functional recovery in soldiers and civilians who have suffered either mild Traumatic Brain Injury (TBIs) or moderate-to-severe TBIs at…
- Trial name
- NCT01552473
- Testing
- Brain Training Program 1, Brain Training Program 2
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- The University of Texas at Dallas
Healthy
A Study in Healthy Men to Test Whether BI 409306, BI 425809 or Lamotrigine Can Reverse the Memory Problems Caused by Ketamine
The main objective of this trail is to investigate if and to what extent BI 409306, BI 425809 and lamotrigine attenuate ketamine induced cognitive deficits.
- Trial name
- NCT04602221
- Testing
- Lamotrigine, BI 409306, BI 425809
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Boehringer Ingelheim
Attention Deficit Hyperactivity Disorder
Study of the Effects of Osmotic-Release Oral System (OROS) Methylphenidate (Concerta) on Attention and Memory
This study investigates whether OROS-methylphenidate improves performance on different aspects of attention and memory in children with Attention-Deficit Hyperactivity Disorder (ADHD).
- Trial name
- CHOP (NCT00530257)
- Testing
- OROS-methylphenidate
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Children's Hospital of Philadelphia
Mild Cognitive Impairment, Memory Disorders
Cognitive Training and Neuroplasticity in Mild Cognitive Impairment
The purpose of this study is to evaluate if systematic cognitive training can improve cognitive performance in participants (55 and older) with memory loss.
- Conditions
- Mild Cognitive Impairment, Memory Disorders, Memory Impairment, Cognitive Impairment
- Trial name
- CogTraining (NCT03205709)
- Testing
- Computerized Cognitive Training, Crossword Puzzles
- Where
- 2 sites in United States
- Volunteers
- 107 people
- Sponsor
- New York State Psychiatric Institute
Memory Impairment
Better Memory With Literacy Acquisition Later in Life
This study aims to discover whether acquiring basic-literacy in adulthood can improve episodic memory and brain structural and functional connectivity.
- Trial name
- NCT04473235
- Testing
- Literacy training, Non-Literacy training
- Where
- Brazil
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Caregivers of Alzheimer's Disease or Memory Problem Patients
Caring for the Caregiver Network
The prevalence of family caregivers is projected to increase in concert with the projected increase in number of AD patients. The focus of the study is to gather systematic data on the acceptability and efficacy of a unique…
- Trial name
- NCT03049501
- Testing
- Caregiving condition, Nutrition condition
- Where
- United States
- Volunteers
- 244 people, healthy volunteers welcome
- Sponsor
- University of Miami