Clinical trials: Memory Deficit
Healthy, Amusia, Congenital
Auditory Deficits in Congenital Amusia (AMUSIE CONGENITALE)
The project studies auditory deficits in congenital amusia at the behavioral and neurophysiological levels. The auditory processes investigated are pitch discrimination, short-term memory, sound-induced emotions.
- Trial name
- NCT03094624
- Testing
- Neuropsychological and neurophysiological tests, Experiment 1, Experiment 2
- Where
- France
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Memory Impairment
The Efficacy of Phosphatidylserine-Omega3 in Elderly Subjects With Memory Impairment
The primary objective of this trial is to assess the ability of Phosphatidylserine-Omega3 to improve cognitive performance in elderly subjects with memory impairment.
- Trial name
- NCT00736034
- Testing
- Phosphatidylserine-Omega3 (SharpPS™-Gold)
- Where
- Israel
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Enzymotec
Schizophrenia, Cognitive Deficits
Augmentation of Working Memory Training With Transcranial Direct Current Stimulation in Patients With Schizophrenia
Cognitive impairment is a core symptom of schizophrenia and is in a large part responsible for the poor psychosocial outcome of the disorder.
- Trial name
- NCT03621540
- Testing
- active tDCS, Adaptive working memory training
- Where
- 2 sites in Germany
- Volunteers
- 37 people
- Sponsor
- University Hospital Tuebingen
Cognitive Decline, Alzheimer Disease
Effects of Real vs. Soundless Acoustic Stimulation During Deep Sleep on Brain Activity, Memory, and Blood Biomarkers in Older Adults (60-85) With Mild Memory Impairment
This study aims to explore a non-invasive way to improve memory and slow cognitive decline in older adults by enhancing sleep quality.
- Conditions
- Cognitive Decline, Alzheimer Disease, Subjective Cognitive Decline (SCD), Mild Cognitive Impairment (MCI)
- Trial name
- NCT06669546
- Testing
- Phase-locked auditory stimulation (PLAS)
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- University of Bern
Focal Epilepsy, Temporal Lobe Epilepsy
Spatial Scene Recognition Memory in Epilepsy Surgery
This study investigates the anatomical and physiological basis of spatial scene recognition memory in patients with temporal lobe epilepsy and temporal lobe lesions.
- Conditions
- Focal Epilepsy, Temporal Lobe Epilepsy, Medically Refractory Epilepsy, Memory Disorders
- Trial name
- NCT07580183
- Testing
- Virtual Tour Recognition Memory Task, Intracranial EEG Recording with Research Electrodes (Aim III only), MRI Neuroimaging and Neuropsychological Assessment (Aim I)
- Where
- 2 sites in United States
- Volunteers
- 620 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Mild Cognitive Impairment, Mild Neurocognitive Disorder
Noninvasive Brain Stimulation for Mild Cognitive Impairment
The goal of this study is to test the efficacy of repetitive Transcranial Magnetic Stimulation (rTMS) as a treatment for Mild Cognitive Impairment (MCI).
- Conditions
- Mild Cognitive Impairment, Mild Neurocognitive Disorder, Cognitive Decline, Mental Deterioration
- Trial name
- NCT03331796
- Testing
- Active rTMS (Bilateral DLPFC), Active rTMS (Bilateral LPC)
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- Palo Alto Veterans Institute for Research
Healthy, Self-reported Memory Problems
A Study to Investigate the Safety and Efficacy of NeuroQ on Cognitive Function in Health Adults with Self-Reported Memory Problems
The objective of this study is to investigate the safety and efficacy of NeuroQ on cognitive function in a North American population of healthy adults with self-reported memory problems compared to placebo.
- Trial name
- NCT06672094
- Testing
- NeuroQ
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- LifeSeasons Inc.
Age-Related Memory Disorders
A Study to Evaluate The Effects Of a Multivitamin/Mineral With Ginko In Subjects With Age Associated Memory Impairment
A Study to evaluate the cognitive effects and tolerance of a Multi-Vitamin/Mineral Preperation containing Gingko in elderly subjects with age associated memory impairment.
- Trial name
- NCT01160692
- Testing
- Multivitamin/Multimineral/Ginkgo (BAY 81-2775)
- Where
- United Kingdom
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Bayer
ADHD
Working Memory Training and Neurofeedback for Children With ADHD, a Pilot Study
This pilot study compares the effect of working memory training and neurofeedback in non-medicated children age 7 to 13 years with ADHD.
- Trial name
- NCT02754336
- Testing
- Cogmed Robomemo, working memory training, Othmer, neurofeedback
- Where
- Norway
- Volunteers
- 6 people
- Sponsor
- Helse Stavanger HF
Parkinson Disease, Mild Cognitive Impairment
Uncovering a Novel Therapeutic Target to Reduce Dementia Risk in Parkinson's Disease
The present study is a proof-of-concept clinical trial to test the efficacy of low doses of a repurposed anti-epileptic drug (levetiracetam) in treating memory problems in Parkinson's disease (PD).
- Conditions
- Parkinson Disease, Mild Cognitive Impairment, Memory Impairment
- Trial name
- TRIP (NCT04643327)
- Testing
- Levetiracetam
- Where
- Australia
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- The University of Queensland
Mild Cognitive Impairment, Memory Impairment
Enhancing Frontal Lobes Plasticity in Mild Cognitive Impairment
More than 5 million people live with Alzheimer's dementia (AD) in North America. No effective treatment exists yet probably because by the time AD has developed it is too late to intervene.
- Trial name
- PAS-MCI (NCT04583215)
- Testing
- Paired Associative Stimulation (PAS)
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Dementia
Perceptions Regarding Investigational Screening for Memory Problems in Primary Care
The purpose of this study is to conduct a cross-sectional survey of primary care patients to better understand their perceptions of the risks and benefits of a screen and subsequent diagnostic confirmation of dementia.
- Trial name
- PRISM-PC (NCT00759252)
- Where
- United States
- Volunteers
- 954 people, healthy volunteers welcome
- Sponsor
- Indiana University
Attention Deficit Disorder
Neurofeedback and Working Memory Training for Children and Adolescents With ADHD
The purpose of this study is to investigate if neurofeedback and working memory training improves core symptoms of ADHD in children and adolescents.
- Trial name
- KITE (NCT01841151)
- Testing
- SCP training, Live Z-score training, WM training
- Where
- Sweden
- Volunteers
- 202 people
- Sponsor
- Karolinska Institutet
Memory Deficit
To Drill or Not to Drill: Do Memory Drills Help Train the Ability to "Remember to Remember" in Veterans
The goal of this clinical trial is to memory drilling works in improving the ability to remember to do something later in treatment-seeking veterans.
- Trial name
- PMIS (NCT06656637)
- Testing
- Memory Drilling, Compensatory Strategies, Cognitive Processing Therapy
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of California, Los Angeles
Aging, Anxiety
Neurobiological Mechanisms of Aging and Stress on Prospective Navigation
Two hallmarks of both healthy aging and age-related disease are 1) memory and navigational deficits, particularly in orienting towards goal locations and planning how to navigate to them, and 2) increased susceptibility to stress…
- Conditions
- Aging, Anxiety, Memory Impairment
- Trial name
- NCT03896529
- Testing
- Anticipatory psychological stress
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Georgia Institute of Technology
Multiple Sclerosis
Memory Rehabilitation Strategies in Patients With Multiple Sclerosis
The clinical characteristics of MS are extremely variable from one patient to another. In about 60% of cases, motor disabilities are associated with cognitive deficits.
- Trial name
- NCT05462678
- Testing
- Cognitive Rehabilitation, Combined Rehabilitation, Motor Rehabilitation
- Where
- 2 sites in Italy
- Volunteers
- 60 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Healthy Participants, Healthy Population
Evaluate the Safety and Feasibility of tACS With the Miamind Neurostimulator in Healthy Participants
The present study aims to assess the safety and feasibility of repeated transcranial alternating current stimulation (tACS) by the Miamind Neurostimulator in a cohort of healthy participants.
- Trial name
- MindStim (NCT05999916)
- Testing
- Personalized Miamind Neurostimulator
- Where
- Switzerland
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Bottneuro AG
Mild Cognitive Impairment
Network-guided TMS in Early Alzheimer's Disease
The proposed research will test a novel network-based neurostimulation approach using MRI-derived measures of brain connectivity to establish target sites for neurostimulation and test for the enhancement of memory function…
- Trial name
- NetTMS (NCT04549155)
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Duke University
Stroke (CVA) or TIA, Memory Impairment
Investigating the Efficacy of ApplTree on Prospective Memory in Stroke
After a stroke, people can experience memory problems, including difficulty remembering to do things in the future - termed "prospective memory".
- Trial name
- NCT05658315
- Testing
- ApplTree smartphone application
- Volunteers
- 6 people
- Sponsor
- NHS Greater Glasgow and Clyde
Healthy, Mild Cognitive Impairment
Supporting Episodic Memory With Transcranial Direct Current Stimulation in Healthy Controls and Dementia Patients
Previous studies showed that anodal tDCS applied over the dorsolateral prefrontal cortex (DLPFC) improved episodic memory performance, indicating a possible use as an intervention for patients suffering from memory impairments.
- Conditions
- Healthy, Mild Cognitive Impairment, Alzheimer Disease
- Trial name
- NCT03227185
- Testing
- real anodal transcranial direct current stimulation (tDCS)
- Where
- Switzerland
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Bern