Clinical trials: Memory
Alcohol Use Disorder, Alcohol Dependence
Altering Memories That Increase Risk of Relapse in Alcohol Use Disorders
The purpose of this study is to examine the effects of rapamycin (sirolimus) versus a placebo, an inactive substance, on responses to alcohol cues in individuals with alcohol use disorder.
- Trial name
- NCT03732248
- Testing
- Rapamycin
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Parkinson's Disease, Mild Cognitive Impairment
A Trial of Neurocognitive and Supportive Therapy Interventions for Individuals With Parkinson's Disease
This randomized, controlled trial (RCT) evaluates the benefits of memory and problem solving training compared to supportive therapy in individuals with Parkinson's Disease with Mild Cognitive Impairment (MCI) and their support…
- Trial name
- NCT01646333
- Testing
- Memory and Problem-Solving Intervention, Supportive Therapy
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Virginia Commonwealth University
Healthy Volunteers (HV)
Electrical Nerve Stimulation During Sleep for Memory Consolidation
The purpose of this study is to investigate the effects of transcutaneous electrical nerve stimulation (eTNS) applied during sleep on memory consolidation and brain-body physiological coupling.
- Trial name
- NCT07658274
- Testing
- 120 Hz Transcutaneous Electrical Nerve Stimulation, 2 Hz Transcutaneous Electrical Nerve Stimulation
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Xidian University
Sickle Cell Disease, Cognitive Impairment
Cognitive Rehabilitation in Sickle Cell Disease
The majority of school-age children with sickle cell disease (SCD) experience neurocognitive deficits, even in the absence of stroke.
- Trial name
- NCT01793740
- Testing
- Cogmed
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Duke University
Healthy
Impact of Resveratrol on Brain Function and Structure
The study will investigate whether resveratrol could provide positive effects on memory and brain structures and functions in healthy elderly participants.
- Trial name
- NCT02621554
- Testing
- resveratrol supplementation
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Max Planck Institute for Human Cognitive and Brain Sciences
Alzheimer's Dementia (AD)
AMPER Proof of Concept Study
The AMPER (Agent-based Memory Prosthesis to Encourage Reminiscing) system has been built to help people with Alzheimer's disease by improving their memory recall and quality of life.
- Trial name
- AMPER (NCT06894953)
- Testing
- Personalised Agent-based Memory Prosthesis to Encourage Reminiscing (AMPER), Non-Personalised Agent-based Memory Prosthesis to Encourage Reminiscing (AMPER)
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University of Strathclyde
Schizophrenia
Effects of Galantamine on Cognition
Schizophrenia is a chronic disorder with onset of psychosis occurring in late teen early twenties, with cognitive impairments and negative symptoms frequently emerging much earlier.
- Trial name
- NCT01100775
- Testing
- Galantamine
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Maryland, Baltimore
Sleep Deprivation
fMRI-behavioral Study of Cholinergic Augmentation With Donepezil in Healthy Sleep Deprived Adults
The purpose of this study was to characterize how the anti-cholinesterase inhibitor (AChE-I) donepezil modulates brain regions involved in visual short-term memory, episodic memory and inhibitory efficiency following 24 hours of…
- Trial name
- NCT00800553
- Testing
- donepezil
- Where
- Singapore
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Duke-NUS Graduate Medical School
ADHD With Working Memory Deficits
Brain Stimulation for Working Memory Deficits in Adolescents With ADHD
Working memory (WM) is the foundational cognitive control process of holding information 'in mind' to execute goal-directed behaviors. WM deficits are an established component of ADHD.
- Trial name
- NCT03480737
- Testing
- Magstim Super Rapid2 stimulator, 10 Hz condition, Magstim Super Rapid2 stimulator, iTBS condition
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Bradley Hospital
Attention Concentration Difficulty
Evaluation of a School-Based Attention Training Programme for Improving Concentration
This study evaluates a school-based attention training programme for improving sustained attention in children.
- Trial name
- NCT04698577
- Testing
- Attention Training, Active Control
- Where
- Ireland
- Volunteers
- 36 people
- Sponsor
- University of Limerick
Age-related Cognitive Decline
Study on the Chronic and Acute Effects of Nordic Berry Beverage on Cognitive Function
The aim of the current study is to investigate whether acute and 12-weeks daily intake of Nordic berries can improve cognitive abilities of adults without cognitive disease, and whether the effect can be linked to changes in…
- Trial name
- SCANBerry (NCT05693441)
- Testing
- Active berry product, Reference berry-like product
- Where
- Sweden
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Aventure AB
Schizophrenia
Cue-based Intervention in Prospective Memory and Medication Adherence.
Medication adherence is a major challenge while treating patients with major mental illnesses like schizophrenia and schizoaffective disorder.
- Trial name
- NCT06474195
- Testing
- Cue based intervention, Treatment as Usual
- Where
- India
- Volunteers
- 104 people
- Sponsor
- University of Pittsburgh
Dementia (Diagnosis), Mild Cognitive Impairment
Choose Myself (Before) Losing Myself
The purpose of this study is to see if an educational interactive booklet about how dementia progresses throughout a person's life can be a helpful tool for patients to think about future decisions that might need to be made…
- Conditions
- Dementia (Diagnosis), Mild Cognitive Impairment, Alzheimer's Disease Dementia, Alzheimer's Disease
- Trial name
- CYOA (NCT07846566)
- Testing
- CYOA booklet
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- The Cleveland Clinic
Mild Cognitive Impairment
The Relationship Between Metamemory and Memory in Old Age
The purpose of this research is to explore the relationship of metamemory and memory of elders and to evaluate the effectiveness of a metamemory cognitive intervention on elders with mild cognitive impairment and low memory…
- Trial name
- M&Mresearch (NCT02113345)
- Testing
- Metamemory Cognitive Intervention
- Where
- Hong Kong
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Alzheimer Disease, Mild Cognitive Impairment
Memory Enhancement Using Transcranial Alternating Current Stimulation
The 32 million Alzheimer's disease (AD) and 69 million prodromal AD patients worldwide contribute to a large economic burden. Effective and safe therapies that slow or prevent the progression from mild cognitive impairment (MCI)…
- Trial name
- Memento (NCT06202872)
- Testing
- Gamma (40 Hz) tACS at the precuneus region
- Where
- Netherlands
- Volunteers
- 26 people
- Sponsor
- Amsterdam UMC, location VUmc
Mild Cognitive Impairment
A Study of a Self-Administered Memory Screening Test With Automated Reporting (SAMSTAR) in Participants With Mild Cognitive Impairment
The purpose of this study is to evaluate the psychometric properties of a Self-administered Memory Screening Test with Automated Reporting (SAMSTAR) adapted from the Rey Auditory Verbal Learning Test (RAVLT) in normal control…
- Trial name
- NCT02419183
- Testing
- SAMSTAR, RAVLT
- Where
- 2 sites in United States
- Volunteers
- 153 people
- Sponsor
- Janssen Research & Development, LLC
Sleep, Age
Age-Related Changes in Sleep-Dependent Emotional Memory
Memory influences emotional well being. Research has shown that having a negative emotional bias contributes to both emotion dysregulation and depression.
- Conditions
- Sleep, Age, Emotional Valence
- Trial name
- NCT04141722
- Testing
- Overnight sleep, Wake
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Amherst
Alzheimer Disease, Cognitive Decline
Smart Cupboard-based System for Memory Assessment in Alzheimer's Patients
The main objective of the research is to create a tool that can make a good diagnosis of cognitive abilities in Alzheimer's patients.
- Trial name
- NCT05202197
- Testing
- Smart cupboard
- Where
- Spain
- Volunteers
- 13 people
- Sponsor
- Universidad de Zaragoza
Dementia, Neurocognitive Disorders
Effect of Individual Reminiscence Therapy in the Elderly People With Neurocognitive Disorders
This research aims to evaluate the ability of individual reminiscence therapy (RT), using a simple reminiscence format, to improve the overall cognitive function, memory, emotional status and quality of life (QoL) of older adults…
- Conditions
- Dementia, Neurocognitive Disorders, Cognitive Impairment, Cognitive Dysfunction
- Trial name
- NCT04658394
- Testing
- Reminiscence therapy
- Where
- 13 sites in Portugal
- Volunteers
- 122 people
- Sponsor
- Rsocialform - Geriatria, Lda
Parkinson Disease, Cognitive Impairment
Cognitive Training in Parkinson's Disease, the iPARK Study
The aim of the iPARK-study is to investigate the effects of a process-based cognitive training program with focus on working memory in patients with Parkinson's Disease (PD).
- Trial name
- iPARK (NCT03680170)
- Testing
- Working memory updating training
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Umeå University