Clinical trials: Memory
Traumatic Brain Injury, Posttraumatic Stress Disorder
Strategic Memory and Reasoning Training for Cognitive Problems
The focus of this study is to test a treatment program (Strategic Memory Advanced Reasoning Training; SMART) that was developed to address specific brain functions found to be crucial for the recovery following traumatic brain…
- Trial name
- SMART (NCT04554537)
- Testing
- SMART, Brain Health Workshop
- Volunteers
- 100 people
- Sponsor
- Dr. Kristin Samuelson
Major Depression, Anxiety Disorder
A Working Memory Training to Decrease Rumination in Depressed and Anxious Individuals
Dysfunctioning executive functioning, including working memory (WM), is related to rumination. Findings show that working memory capacity (WMC) can be increased by training.
- Trial name
- NCT02119975
- Testing
- Working memory training
- Where
- Netherlands
- Volunteers
- 98 people
- Sponsor
- Erasmus Medical Center
Trichotillomania
Cognitive Training in Patients With Trichotillomania (Hair-pulling Disorder)
The principal aim of this study is to establish the impact of Cognitive Training in patients with primary Hair-pulling Disorder.
- Trial name
- CTTTM (NCT02794753)
- Testing
- Working memory training, Game
- Where
- South Africa
- Volunteers
- 40 people
- Sponsor
- University of Stellenbosch
Cannabis, Memory
Cannabis Observations on Brain Waves, Retrieval, and Attention: Experiment 4
This study investigates the impact of ∆9-tetrahydrocannabinol (THC) and cannabidiol (CBD) on recognition memory in healthy, regular cannabis users.
- Conditions
- Cannabis, Memory, Electroencephalography
- Trial name
- COBRA 4 (NCT07679581)
- Testing
- Cannabis (smoked flower)
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- L. Cinnamon Bidwell
Traumatic Brain Injury
Functional Connectivity as a Biomarker of rTMS
Background: Traumatic brain injury (TBI) damages the connections between brain cells. This can lead to problems like memory loss.
- Trial name
- NCT03050801
- Testing
- rTMS
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Dementia, Mild Cognitive Impairment
Case-Finding for Neurocognitive Disorders in Pavia
Dementia is a global public health challenge with a heavy caregiving burden, impacting families, communities, and healthcare systems. It is a priority in healthcare planning, with focus on early diagnosis and ongoing support.
- Trial name
- C-FiND Pavia (NCT06983119)
- Testing
- Case-finding for Neurocognitive Disorders
- Where
- Italy
- Volunteers
- 490 people
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
Brain Fog
Transcranial Direct Current Stimulation (tDCS)
Cognitive impairment refers to when an individual struggles to learn, concentrate, remember, or make decisions. This can be due to underlying neurological diseases (i.e.
- Trial name
- tDCS (NCT05524233)
- Testing
- Active Transcranial Direct Stimulation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Baylor College of Medicine
Alzheimer Disease, Physical Activity
Inspiring Seniors Towards Exercise Promotion to Protect Cognition
The goal of this clinical trial is to test the benefits of beat-accented music stimulation (BMS) for behavioral changes of physical activity (PA) in older adults with subjective memory complaints.
- Trial name
- iSTEP+ (NCT06496425)
- Testing
- Beat-accentuated, personalized music stimulation (BMS), Strength Training (ST), Aerobic exercise (AE)
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Emory University
COVID-19, Neuro-Degenerative Disease
Randomised Clinical Trial to Evaluate the Efficacy of an Online Cognitive Rehabilitation Programme (COPERIA-COG) for Patients With Persistent COVID-19
The pandemic caused by SARS-CoV-2 infection has led to the emergence of diffuse and heterogeneous persistent symptoms in addition to the well-known acute symptoms, which have come to be referred to as persistent COVID.
- Conditions
- COVID-19, Neuro-Degenerative Disease, Psychological, SARS CoV 2 Infection
- Trial name
- COPERIA-COG (NCT05629897)
- Testing
- Sessions of cognitive stimulation
- Where
- 2 sites in Spain
- Volunteers
- 88 people
- Sponsor
- Fundacin Biomedica Galicia Sur
Cannabis, Dependence
Effects of Sativex(Registered Trademark) and Oral THC on Attention, Affect, Working Memory, Reversal Learning, Physiology and Brain Activation
Background: The therapeutic modalities of cannabis have received more research attention recently with the discovery of its ability to stimulate appetite and to provide pain and nausea relief in patients with AIDS, cancer, and…
- Conditions
- Cannabis, Dependence, Cannabis Abuse, Pharmacokinetics
- Trial name
- NCT01037608
- Testing
- Sativex(Registered Trademark), THC
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Heart Failure, Cardiac Failure
Heart Failure Insomnia Treatment Study
The purpose of this study is to compare a short, behavioral treatment for insomnia with sleep monitoring to determine whether these approaches are effective in reducing insomnia and improving sleep quality among patients with…
- Conditions
- Heart Failure, Cardiac Failure, Congestive Heart Failure, Insomnia
- Trial name
- H-FITS (NCT03636880)
- Testing
- Brief treatment for Insomnia, Sleep Monitoring
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Ohio State University
Inhibition (Psychology), Updating
Attentional Control Training in Older Adults: Efficacy, Transfer and Brain Substrates
Formal education and cognitively stimulating hobbies and profession have a protective effect against age-related cognitive decline and Alzheimer's disease.
- Conditions
- Inhibition (Psychology), Updating, General Knowledge, No Training
- Trial name
- NCT03532113
- Testing
- Updating, Inhibition, General knowledge
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal
Alzheimer Disease
The Effect of Repeated Transcranial Magnetic Stimulation on Off-line Resting Electroencephalographic Signal in Alzheimer's Disease
The purpose of this study is to examine whether the rTMS (repetitive Transcranial Magnetic Stimulation) could change cortical excitability measured by off-line EEG in Alzheimer's Disease (AD) patients.
- Trial name
- NCT01970150
- Testing
- rTMS real
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Mild Cognitive Impairment
Neurological Changes With a Memory Self-efficacy Training Protocol
Confidence in one's ability to accomplish a task, more formally known as self-efficacy, is an important psychological variable that can influence how the investigators perform on various tasks.
- Trial name
- NCT04077320
- Testing
- Memory Self-Efficacy Training, General Education
- Where
- Canada
- Volunteers
- 28 people
- Sponsor
- Western University, Canada
Dyspnea, Breathlessness
Breathlessness During Exercise: Experience and Memory
Breathlessness during exertion is a major limiting factor for patients' physical capacity and activity. Increased exertional breathlessness often results in impaired activity, spiraling deconditioning and further worsening of…
- Trial name
- NCT03458182
- Testing
- Added exercise
- Where
- Sweden
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Magnus Ekström
Brain Tumor
Memantine +/- Raloxifene for Cognitive Preservation After Radiation Therapy to the Brain
The study investigators are testing to see if patients receiving radiation treatment for brain cancer along with raloxifene plus memantidine take longer to develop memory issues.
- Trial name
- MemoryRT (NCT07470606)
- Testing
- Memantine, Raloxifene
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Attention Deficit Hyperactivity Disorder, Attention Deficit Disorder
Network Control TMS fMRI
This study uses different types of functional magnetic resonance imagining (fMRI) to generate individual transcranial magnetic stimulation (TMS) targets.
- Conditions
- Attention Deficit Hyperactivity Disorder, Attention Deficit Disorder, Working Memory
- Trial name
- NCT05736458
- Testing
- Transcranial Magnetic Stimulation (TMS), High controllability TMS target
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Working Memory
Modulation of Brain Oscillations Underlying Working Memory
This study will use novel transcranial alternating current stimulation (tACS) protocols and electroencephalography (EEG) to modulate and measure brain oscillations that underlie working memory.
- Trial name
- NCT05923606
- Testing
- Active tACS
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Healthy
Transcriptomics Signature of Anti Vaccinia Memory B Cells
Analyse the transcriptomic signature of anti vaccinia memory B cells at a short time after vaccination as compared to the signature already established in long-lived memory B cells.
- Trial name
- NCT02556489
- Where
- France
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Dementia
BELIDE: Better Living With Non-memory-led Dementia
Around 48 million people worldwide 1 live with dementia, of whom 3.9 million start with symptoms before the age of 65 (young-onset dementia).
- Trial name
- BELIDE (NCT06241287)
- Testing
- Better Living with Non-memory led Dementia programme, Waiting list
- Where
- United Kingdom
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- University College, London