Clinical trials: Meibomian Gland Dysfunction (Disorder)
Chalazia, Chalazion
Intralesional Tetracycline Injection in the Treatment of Chalazia
The investigators propose a study to investigate the role of tetracycline injection into chalazia versus observation alone. The investigators hypothesize tetracycline injection will result in a significant decrease in lesion size…
- Trial name
- TET (NCT01763437)
- Testing
- Tetracycline
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Skin Laxity, Meibomian Gland Dysfunction
Evaluation of Ocular Surface Changes Following RF Electrocoagulation Treatment of the Periorbital Region
This protocol will evaluate THERMIeyes® for its ability to treat periorbital skin laxity and wrinkles and monitor ocular surface changes and their effect on evaporative dry eye associated with MGD.
- Trial name
- NCT03280069
- Testing
- THERMIeyes® 20 RF System
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ophthalmic Consultants of Long Island
Dry Eye Disease, Meibomian Gland Disease
Treating Meibomian Gland Disease in a Pediatric Population
Dry Eye Disease (DED) is commonly encountered among eye care professionals. DED is a disease of the tears and ocular surface that is multi-factorial resulting in a wide range of symptoms and signs with potentially damaging…
- Trial name
- LLLT in Peds (NCT07229001)
- Testing
- Low level light treatment, warm compress and artificial tear
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Illinois College of Optometry
Meibomian Gland Dysfunction, Dry Eye Syndromes
Meibomian Gland Dysfunction Management With ZEST Protocol
The purpose of this study is to investigate if cleaning the eyelid margin with the ZEST protocol (Zocular Eyelid System Treatment) in patients intolerant to contact lens wear consequent to Meibomian gland dysfunction (MGD) will…
- Conditions
- Meibomian Gland Dysfunction, Dry Eye Syndromes, Ocular Surface Disease
- Trial name
- NCT03968731
- Testing
- Zocular Eyelid System Treatment
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of the Incarnate Word
Meibomian Gland Dysfunction
Meibography and Tear Scan Using the Oculus Keratograph 4
The purpose of this study is to look at both the meibomian glands and the tear film using a new clinical instrument marketed in Canada which was recently acquired by the Centre for Contact Lens Research.
- Trial name
- KITCHENER (NCT01382108)
- Where
- Canada
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Dry Eye Disease, Meibomian Gland Dysfunction
Preoperative iLux on Cataract Surgery Derived Dry Eye Disease Due to Meibomian Gland Dysfunction
This prospective study will investigate the effect of pre-operative Systane iLux system administration in treated cataract induced dry eye disease.
- Conditions
- Dry Eye Disease, Meibomian Gland Dysfunction, Cataract Senile, Dry Eye Syndromes
- Trial name
- NCT06483750
- Testing
- Systane iLux Treatment
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- George Washington University
Evaporative Dry Eye Disease, Meibomian Gland Dysfunction
Clinical Study Using Eye Lipid Mobilizer (ELM) With Heat and Vibration To Treat Evaporative Dry Eye Disease
The goal of this clinical trial is to evaluate the Eye Lipid Mobilizer (ELM) for the treatment of evaporative dry eye disease associated with meibomian gland dysfunction.
- Trial name
- ELM (NCT06242860)
- Testing
- ELM
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Eyedetec Medical, Inc.
MGD-Meibomian Gland Dysfunction, Positron-Emission Tomography
PET-CT Imaging Features of Meibomian Glands
Analysis the results of Dry eye analysis results and PET-CT imaging comprehensively
- Conditions
- MGD-Meibomian Gland Dysfunction, Positron-Emission Tomography, Dry Eye
- Trial name
- NCT06324890
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Zhongnan Hospital
Dry Eye, MGD-Meibomian Gland Dysfunction
Study on Prevention and Treatment of Dry Eye in Patients Using Glaucoma Drops
A multicenter randomized controlled trial on prevention and treatment of ocular surface injury and meibomian gland dysfunction in patients using anti-glaucoma eye drops.
- Trial name
- NCT03515187
- Testing
- 0.3% sodium hyaluronate ophthalmic solution, 0.1% sodium bromide solution, Meibomian gland massage
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Shenzhen Hospital of Southern Medical University
Dry Eye Disease, Dry Eye Syndromes
iTear Single-center, Open-label, Single-arm Study
This study aims to evaluate the effectiveness and safety of a device, iTEAR100 Neurostimulator (the device), which is designed to help people with Dry Eye Disease (DED) who are not satisfied with using artificial tears.
- Conditions
- Dry Eye Disease, Dry Eye Syndromes, Dry Eye, Meibomian Gland Dysfunction
- Trial name
- NCT06525961
- Testing
- iTEAR100 Neurostimulator
- Where
- Hong Kong
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Meibomian Gland Dysfunction, Dry Eye Disease
Refractory Meibomian Gland Dysfunction and Plasma Jet
PURPOSE: The investigators propose a new treatment for refractory Meibomian Gland Dysfunction (MGD) patients with plasma jet to remove the hyperkeratinization layer from the lid margin to unblock terminal gland ducts and use…
- Conditions
- Meibomian Gland Dysfunction, Dry Eye Disease, Evaporative Dry Eye, Inflammation
- Trial name
- NCT04608942
- Testing
- Jett Plasma Medical Lift, Mechanical Debridement
- Where
- 2 sites in Brazil
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Dry Eye Syndromes
Clinical Efficacy of Intense Pulsed Light(IPL) Procedure in Dry Eye Patient
Clinical efficacy of Intense Pulsed Light(IPL) procedure in dry eye patients with meibomian gland dysfunction prior to cataract surgery.
- Trial name
- NCT04391907
- Testing
- IPL
- Where
- South Korea
- Volunteers
- healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Meibomian Gland Dysfunction, Dry Eye
Lipiflow vs iLux Patient Acceptance and Comfort Study
This study was designed to compare patient acceptance, comfort, and preference between two meibomian gland clearing devices (Lipiflow vs, iLux).
- Trial name
- NCT04454983
- Testing
- Lipiflow Thermal Pulsation System, iLux System
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Epstein, Arthur B., OD, FAAO
Dry Eye, Meibomian Gland Dysfunction
Crosslinked Hyaluronic Acid With Liposomes and Crocin in Dry Eye
A total of 50 eyes were analyzed (25 patients). The subjects selected were over 18 years of age. No gender distinction was made in the choice of subjects. All subjects were carriers of silicone hydrogel contact lenses.
- Conditions
- Dry Eye, Meibomian Gland Dysfunction, Dry Eye Syndromes
- Trial name
- NCT03617315
- Testing
- Hylauronic Acid
- Where
- Spain
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Seville
Meibomian Gland Dysfunction, Evaporative Dry Eye
Tear Film Innovations iLux Safety Study
The objective of this study was to measure the temperature of the cornea and surrounding eye tissue temperature immediately after heating the eyelids with the iLux device using the protocol treatment profile.
- Trial name
- NCT03055897
- Testing
- iLux 2020 System
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Tear Film Innovations, Inc.
MGD-Meibomian Gland Dysfunction
Single Lipiflow Treatment to Reduce Pharmacologic Burden in DED
Purpose: To evaluate the efficacy of vectored thermal pulsation treatment in subjects with a history of dry eye disease currently using a topical immunomodulator medication.
- Trial name
- Reduce (NCT06542276)
- Testing
- Thermal Vectored Pulsation
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dunes Eye Consultants
Meibomian Gland Dysfunction
Morphological Analysis of Meibomian Glands
An automated quantitative meibomian gland analyzer based on all kinds of infrared meibomian gland images was develop to obtain more detail in meibomian gland, including width, length, area, signal intensity correlated to the…
- Trial name
- NCT04052841
- Testing
- Thermal pulsation, Intense pulsed light therapy, Manual warm compresses
- Where
- 2 sites in China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Meibomian Gland Dysfunction, Evaporative Dry Eye
Dextenza With ILUX for Treatment of MGD
To evaluate the benefit of treatment with a physician administered intracanalicular dexamethasone insert in evaporative dry eye disease (DED) patients with meibomian gland disfunction (MGD) and underlying inflammation undergoing…
- Trial name
- NCT04658927
- Testing
- Dexamethasone, 0.4mg, Prednisone acetate, Control
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Warrenville Eyecare
Meibomian Gland Dysfunction (Disorder), Dry Eye Syndromes
Effectiveness and Safety of Intense Pulsed Light in Patients With Meibomian Gland Dysfunction
Meibomian gland dysfunction (MGD) is one of the most common causes of dry eye diseases. Over the past decade, several treatment options in MGD have been extensively studied including warm compression, lid hygiene, ocular…
- Trial name
- NCT03518398
- Testing
- Intense Pulsed Light, Standard treatment
- Where
- Thailand
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Meibomian Gland Dysfunction
Study to Determine the Effect of Azasite on Corneal Surface Irregularity
The purpose of this study is to evaluate the effect of Azasite on patients with corneal surface irregularity (meibomian gland dysfunction).
- Trial name
- NCT01797107
- Testing
- Azasite
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Philadelphia Eye Associates