Clinical trials: Medication Management
Healthy
Drug Drug Interaction of Empagliflozin (BI 10773) and Warfarin in Healthy Volunteers
The objective of the current study is to investigate the bioavailability of BI 10773 and of warfarin after concomitant multiple oral administration of BI 10773 and a single oral dose of warfarin in comparison to BI 10773 and…
- Trial name
- NCT01111331
- Testing
- BI 10773 25 mg, Warfarin 25 mg, Warfarin
- Where
- Germany
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Henna, Hand-Foot Syndrome
Effectiveness of the Henna Application in Patients With Hand-Foot Syndrome: Nested Case-Control Study
Introduction: There is an explanation that there is a connection between the application of henna and the occurrence of hand-foot syndrome, and the purpose and progression of this interaction.
- Conditions
- Henna, Hand-Foot Syndrome, Case-Control Study
- Trial name
- [Henna] (NCT06832501)
- Testing
- Henna
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Hacettepe University
Alcohol Dependence, Alcohol Use Disorder
Extended-release Naltrexone and Care Management for Alcohol Dependent Frequent Emergency Department Users
Our primary aim is to assess the feasibility of initiating treatment in the ED with extended-release naltrexone (XR-NTX) plus care management (CM) vs.
- Trial name
- NCT02445339
- Testing
- XR-NTX+CM (Extended-Release Naltrexone plus Care Management)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- NYU Langone Health
Nursing Student, Simulation
Drug Administration Competency of Nursing Students
The purpose of this study is to examine the effect of a simulation-based education program designed based on cognitive load theory on the development of medication administration competency of nursing students.
- Conditions
- Nursing Student, Simulation, Cognitive Load, Competence
- Trial name
- NCT05837377
- Testing
- Control- standard medication education, Experiment- cognitive load theory based on medication education
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Drug Addiction
Integration of the Therapeutic Workplace in Drug Court
Drug Courts were developed as a therapeutic alternative to incarceration of drug-involved offenders by providing 'judicially supervised' drug abuse treatment and probation for nonviolent offenders in lieu of criminal prosecution…
- Trial name
- NCT00607360
- Testing
- Therapeutic Workplace Intervention
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Opioid-induced Bowel Dysfunction, Constipation Drug Induced
The Efficacy of Acupressure in Managing Opioid-induced Constipation
In a randomized controlled study to evaluate the effect of acupressure application on opioid-related constipation, the Patient Identification Form, Defecation Diary, Visual Analog Scale and Constipation Quality of Life Scale will…
- Trial name
- NCT04876508
- Testing
- Accupressure
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
Healthy
Safety and the Efficacy of a Sublingual Administration of Flumazenil to Reverse the Effect of Hypnotic Drugs in Healthy Adults
The purpose of this study is to evaluate the safety and effectiveness of treatment with sublingual (s/l) Flumazenil in healthy volunteers as reversing the effect of the sleep/hypnotic drugs.
- Trial name
- NCT01071889
- Testing
- Flumazenil
- Where
- Israel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Coeruleus Ltd.
Physician's Role, Administration, Oral
Switching Medications From Intravenous to Oral
In a recent report, drug spending increased by 23.4 percent annually in the inpatient setting from 2013 to 2015 with the average inpatient drug spending increasing from $714 to $990 per admission.
- Trial name
- NCT03666520
- Testing
- Clinical Decision Support prompted to the clinician to convert drug.
- Where
- United States
- Volunteers
- 921 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Cocaine Dependence
Effect of Zonisamide on Cocaine Reinforcement, Craving, and Relapse
This is a residential pilot trial to evaluate the pharmacodynamic interaction between zonisamide and cocaine, with the goal of evaluating zonisamide's potential for the treatment of cocaine dependence.
- Trial name
- NCT01137890
- Testing
- Zonisamide, Cocaine Hydrochloride, Neurocognitive and Performance Battery
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Johns Hopkins University
Behavior Therapy, Cocaine
The Efficacy of Methadyl Acetate (LAAM) and Contingency Management Procedures for Treating Dual Opioid and Cocaine Abuse - 1
Although LAAM, a derivative of methadone, has been successfully used as an alternative to methadone maintenance in opioid addicts, its effect on concurrent opioid and cocaine abuse has not been ascertained.
- Conditions
- Behavior Therapy, Cocaine, Contingency Management, Heroin Dependence
- Trial name
- NCT00158288
- Testing
- LAAM
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Periprocedural Complication
Periprocedural Direct Oral Anticoagulant Management
Direct oral anticoagulants (DOAC) are a new drug group that has been approved for chronic anticoagulation of patients in atrial fibrillation or suffering acute thrombosis, between others.
- Trial name
- RA-ACOD (NCT03182218)
- Testing
- Direct oral anticoagulant
- Where
- 30 sites in Spain
- Volunteers
- 1,100 people
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
Palliative Care
iLIVE Medication Study
The iLIVE medication study is a before-after study where medication optimisation of patients with an estimated life expectancy of six months is investigated. The investigators will include 400 patients in 3 countries.
- Trial name
- iLIVEmed (NCT04717882)
- Testing
- CDSS-OPTIMED
- Where
- 3 sites in Netherlands, Sweden and 1 more
- Volunteers
- 400 people
- Sponsor
- Prof. dr. Stefan Sleijfer
Healthy
To Evaluate the Pharmacokinetic Drug Interactions, Safety and Drug Tolerance in Healthy Volunteers
A randomized, open-label, multiple-dose, 2x3 crossover clinical trial to investigate the pharmacokinetic drug interaction of JW0201 and C2103 or C2104 after oral administration in healthy adults
- Trial name
- NCT05463497
- Testing
- Treatment A, Treatment B, Treatment C
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- JW Pharmaceutical
Asthma
To Evaluate Newly Developed Pictogram Cards and Their Utility in Improving Inhaler Techniques in Asthmatic Patients
To evaluate newly developed pictogram cards and their utility in improving inhaler techniques in asthmatic patients.
- Trial name
- NCT06562764
- Testing
- Counselling by the Trained Pharmacist, Pictograms Cards and Counselling by the Trained Pharmacist
- Where
- Pakistan
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Islamia University of Bahawalpur
Diabetes, Obesity
AIManage Using an AI-driven CDS and Chatbot
The objective of this project is to define and test the GenAI-powered Clinical Decision Support (CDS) tool, AIManage, providing a broad range of incretin mimetic medication management services to optimize dose titrations.
- Conditions
- Diabetes, Obesity, Medication Side Effects
- Trial name
- NCT07546357
- Testing
- AIManage
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- NYU Langone Health
Gastric Ulcer
Efficacy of TAK-438 Compared to AG-1749 (Lansoprazole) in the Treatment of Gastric Ulcer
The purpose of this study is to investigate the efficacy of TAK-438, once daily (QD), compared to lansoprazole in patients with gastric ulcer.
- Trial name
- NCT01452711
- Testing
- TAK-438, Lansoprazole
- Where
- 64 sites in Japan
- Volunteers
- 482 people
- Sponsor
- Takeda
Stroke
Mobile Terminal Based Management of Stroke Secondary Prevention Adminstration Effect Research
The investigators want to verify whether mobile application based on stroke strengthen prevention management is more effective than traditional management model or open stroke management platform.
- Trial name
- NCT02618265
- Testing
- Mobile terminal, traditional management, website platform management
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Peking University Third Hospital
HIV Infections
A Study of 1592U89 and Ethanol When Given Together to HIV-Infected Patients
The purpose of this study is to see how the body processes 1592U89 and ethanol (pure grain alcohol) when they are given together.
- Trial name
- NCT00002198
- Testing
- Abacavir sulfate
- Where
- United States
- Sponsor
- Glaxo Wellcome
HIV Infections
A Study to Test the Safety, Tolerance, and Metabolism of Abacavir (1592U89, ABC) With Standard Zidovudine (ZDV) Therapy in Newborn Infants Born to HIV-1 Infected Women
The purpose of this study is to determine the safety, tolerance, and metabolism of single-dose and multiple-dose abacavir (ABC) in HIV-exposed infants receiving standard postnatal treatment with zidovudine (ZDV).
- Trial name
- NCT00000864
- Testing
- Abacavir sulfate, Zidovudine
- Where
- 13 sites in United States, Puerto Rico
- Volunteers
- 60 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Sports Drug Abuse, Abuse of Steroids or Hormones
Administration of Clomiphene: Short and Long Term Metabolism in an Anti-Doping Setting
Clomiphene (Clomid) is a drug FDA approved to treat female infertility, however, it is often used by men in an off-label setting to both treat male infertility and in a multitude of sports disciplines to increase performance.
- Trial name
- NCT03028532
- Testing
- Clomid
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Stuart Willick