Clinical trials: Medication Abuse
Adolescent Substance Abuse, Attention Deficit Hyperactivity Disorder
Family-Based Protocol for Medication Integration in Treatment of Comorbid ASU/ADHD in Routine Care
The goal of this proposal is to develop and pilot a brief protocol designed to systematically integrate pharmacological interventions for attention deficit hyperactivity disorder (ADHD) into behavioral treatment services for…
- Trial name
- NCT01539941
- Testing
- Medication integration protocol
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- The National Center on Addiction and Substance Abuse at Columbia University
Substance Use Disorders, Pregnancy Related
The Oklahoma Parent-Child Assistance Program
The Parent-Child Assistance Program (PCAP) helps mothers who have used alcohol, opioids, or other drugs during pregnancy and their children through the work of highly trained, closely supervised case managers.
- Conditions
- Substance Use Disorders, Pregnancy Related, Alcohol Use Disorder (AUD), Alcohol Use Complicating Pregnancy, First Trimester
- Trial name
- NCT05534568
- Testing
- Parent-Child Assistance Program
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of Oklahoma
Cocaine Dependence
Effects of Propranolol on Responses to Drug-Related Imagery Scripts
Background: Relapse to drug abuse is thought to result, in many cases, from exposure to cues that trigger drug-related memories or emotional associations for example, the association between the sight of a crack pipe and a set of…
- Trial name
- NCT00688805
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Adolescent, Substance Use
Martial Arts as Early Intervention for Teen Drug Abuse
This is a Stage 1A/1B behavioral therapy development project with the aim of developing and piloting an early intervention based upon traditional martial arts for adolescents who are in the early stages of substance use/misuse.
- Trial name
- NCT00956527
- Testing
- Modified traditional martial arts training
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Colorado, Denver
Mental Health Disorder, Substance Abuse Drug
Tobacco Cessation Among Smokers Under Alcohol and/or Cannabis Treatment
Aims: To identify the predictors associated with smoking cessation in smokers under treatment for alcohol and/or cannabis treated in drug treatment centers (DTC).
- Conditions
- Mental Health Disorder, Substance Abuse Drug, Alcohol Abuse, Cannabis Use
- Trial name
- ACT-ATAC (NCT04841655)
- Where
- 2 sites in Spain
- Volunteers
- 1,625 people
- Sponsor
- Institut Català d'Oncologia
Prevention, Family Function
Familias Unidas: Preventing Substance Abuse in Hispanic Youth
The focus of this study will be to test the Familias Unidas Intervention program among Hispanic 8th graders in the Miami-Dade County Public School System.
- Conditions
- Prevention, Family Function, Substance Use, Sexual Behavior
- Trial name
- NCT01038206
- Testing
- Familias Unidas
- Where
- United States
- Volunteers
- 746 people, healthy volunteers welcome
- Sponsor
- University of Miami
Smoking, Alcohol Drinking
Tailored Inhibitory Control Training to Reverse EA-linked Deficits in Mid-life
Insufficient inhibitory control is one pathway through which early adversity is related to a range of problems including excessive alcohol use, tobacco use, and unhealthy eating.
- Conditions
- Smoking, Alcohol Drinking, Prescription Drug Abuse, Substance-Related Disorders
- Trial name
- REV (NCT02945371)
- Testing
- Person-centered inhibitory control training, Active behavioral response training
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Suicidal Ideation, Depression
Population Screening Using Smartphone in Milpa Alta
The objective of this study is to make a suicide screening in the entire population of Milpa Alta (approximately 150,000 inhabitants), taking into account other outcomes such as depression, anxiety, alcohol and drugs.
- Conditions
- Suicidal Ideation, Depression, Depressive Disorder, Anxiety
- Trial name
- Smart-screen (NCT04067063)
- Testing
- Self-administered evaluation questionnaire
- Where
- Mexico
- Volunteers
- 150,000 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
HIV Risk Behaviors, Heroin Injection
Efficacy of Drug and Risk Counseling Among Methadone Patients in Jakarta, Indonesia
According to UNAIDS, Indonesia is experiencing one of the most rapidly expanding HIV/AIDS epidemics in Asia. The epidemic in Indonesia has been fueled by injection drug use among heroin users and the national response includes…
- Conditions
- HIV Risk Behaviors, Heroin Injection, Retention in Methadone Treatment
- Trial name
- JAKPRO (NCT01360463)
- Testing
- Behavioral Drug and Risk Counseling (BDRC), methadone maintenance treatment
- Where
- Indonesia
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Opioid-Related Disorders
Trial of Adherence App for Buprenorphine Treatment (TAAB) Study
The purpose of this study is to pilot test a smartphone application that allows video-based directly observed therapy for participants receiving buprenorphine treatment for opioid use disorder in office-based settings.
- Trial name
- NCT03779997
- Testing
- Video-based DOT Application
- Where
- 2 sites in United States
- Volunteers
- 78 people
- Sponsor
- University of Washington
Alcohol Abuse, Drug Abuse
Adventure: Teacher Delivered Personality-targeted Interventions for Substance Misuse
Several personality factors have been shown to be associated with risk for alcohol and substance misuse, and differentiate substance abusers based on clinical profile, treatment response and susceptibility to other forms of…
- Conditions
- Alcohol Abuse, Drug Abuse, Depression, Panic Disorder
- Trial name
- Adventure (NCT00776685)
- Testing
- Personality-targeted interventions
- Where
- United Kingdom
- Volunteers
- 3,190 people, healthy volunteers welcome
- Sponsor
- King's College London
Opioid-Related Disorders, Drug Addiction
Medication Treatment for Opioid Use Disorder in Expectant Mothers: Conceptual Model Assessments Sub-study
This is a sub-study of NIDA CTN Protocol 0080: Medication Treatment for Opioid Use Disorder in Expectant Mothers (MOMs; Unique protocol ID: 2019-0429-1).
- Conditions
- Opioid-Related Disorders, Drug Addiction, Pregnancy Related, Substance Abuse
- Trial name
- MOMs-CMA (NCT03911466)
- Testing
- Buprenorphine Injection, Buprenorphine Sublingual Product
- Where
- 12 sites in United States
- Volunteers
- 97 people
- Sponsor
- T. John Winhusen, PhD
Opioid-related Disorders, Opioid Addiction
ER/LA Opioid Surveillance for Emergency Department Visits and Hospitalizations for Overdose and Poisoning
Study to evaluate the impact of the ER/LA opioid REMS program on the incidence of Emergency Department visits and hospitalizations for overdose/poisoning and death among patients prescribed ER/LA opioid analgesics.
- Conditions
- Opioid-related Disorders, Opioid Addiction, Narcotic Abuse, Drug Abuse
- Trial name
- NCT02866266
- Testing
- Retrospective database review
- Volunteers
- 183,452 people
- Sponsor
- ER/LA Opioid REMS Program Companies (RPC)
Drug Abuse, Cocaine Dependence
Reward Processing in Cocaine Addiction
Background: Cocaine affects the brain's ability to process information. However, different people respond to cocaine in different ways, and differences in brain structure and function may affect how cocaine alters brain activity.
- Trial name
- NCT01036074
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Drug Abuse, Healthy
Abuse Potential of Single Doses of Lorcaserin in Healthy Recreational Polydrug Users
The purpose of this study is to evaluate the abuse potential of lorcaserin in healthy recreational polydrug users.
- Trial name
- NCT00828659
- Testing
- Active Comparator #1, Active Comparator #2, Active Comparator #3
- Where
- Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Eisai Inc.
Cocaine Dependence
Pharmacogenetic Trial of Doxazosin for Treatment of Cocaine Abuse
Cocaine use disorders affect approximately 1.5 million Americans annually. Currently, there are no US Food and Drug Administration approved medications for treatment of cocaine dependence; however, both animal and human studies…
- Trial name
- NCT01953432
- Testing
- Doxazosin
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Drug Abuse Illicit
Method Comparison of Intelligent Fingerprinting Drug Screening System
Prospective, multi-site, open-label, single- or double-dose, randomized, multi-site performance evaluation of accuracy of the Intelligent Fingerprinting Drug Screening System in the hands of intended users: "operators" and…
- Trial name
- NCT07650136
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Intelligent Bio Solutions Inc.
Attention Deficit Hyperactivity Disorder (ADHD)
Experimental Medicine in ADHD - Cannabinoids
Adult patients with ADHD commonly report an improvement in behavioural symptoms when using cannabis with some reporting a preference towards cannabis over their ADHD stimulant medication.
- Trial name
- EMA-C (NCT02249299)
- Testing
- Sativex Oromucosal Spray
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- King's College London
Substance Abuse
Youth Substance Use Prevention/Reduction Through Science-based Drug Abuse Education
Our primary goal is to conduct a pilot study of the effects of a new potential strategy for youth substance abuse prevention - science-based drug education integrated into the high school science curriculum.
- Trial name
- NCT00612482
- Testing
- drug prevention curriculum
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Substance-related Disorders, Drug Addiction
Buprenorphine and Integrated HIV Care
The purpose of this study is to examine the efficacy of providing two levels of psychosocial support along with buprenorphine/naloxone (BUP) maintenance to opioid dependent patients receiving their care in an HIV clinical care…
- Conditions
- Substance-related Disorders, Drug Addiction, Human Immunodeficiency Virus, AIDS
- Trial name
- NCT00317460
- Testing
- Physician Management, Counseling
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Yale University