Clinical trials: Medical Abortion
Termination of Pregnancy (TOP)
Interest of Cervical Dilators in Second Trimester Termination of Pregnancy
The purpose of this study is to evaluate whether the use of cervical dilators for cervical ripening in case of second trimester medical termination of pregnancy (TOP) is effective to reduce duration of labor.
- Trial name
- DILATOP (NCT03194230)
- Testing
- With cervical dilatator
- Where
- France
- Volunteers
- 355 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pregnancy Related
Requests for Medical Termination of Pregnancy for Psychological or Social Maternal Reasons
When the request for termination of pregnancy is made at a term of less than sixteen weeks of amenorrhea, the patients have complete decision-making autonomy. This is called voluntary termination of pregnancy.
- Trial name
- NCT05499325
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Centre Hospitalier de Saint-Denis
Missed Abortion, Medical; Abortion, Fetus
Gemeprost Versus Dinoprostone in First Trimester Miscarriages
Comparison between gemeprost and dinoprostone to evacuate first trimester miscarriages.
- Conditions
- Missed Abortion, Medical; Abortion, Fetus, Incomplete Abortion
- Trial name
- NCT05342467
- Testing
- Gemeprost 1 Mg Vaginal Pessary, Dinoprostone 3 mg
- Where
- 2 sites in Malaysia
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Abortion, Induced
A Randomized Trial of Buccal Compared to Oral Misoprostol Following Mifepristone for Medical Abortion up to 63 Days LMP
This open-label, randomized study will compare the efficacy, safety, and acceptability of mifepristone 200 mg followed in 24-36 hours either by buccal (i.e., in the cheeks) or oral misoprostol 800 mcg for termination of pregnancy…
- Trial name
- NCT00386867
- Testing
- 800 mcg misoprostol via oral or buccal administration
- Where
- 8 sites in United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Miscarriage
Comparison Between Letrozole and Mifepristone in Medical Termination of First Trimester Miscarriages
Prospective interventional study where participants with non-viable pregnancy at 1st trimester will be randomized into two arms, one group will receive conventional treatment with oral mifepristone followed by misoprostol…
- Trial name
- NCT05304273
- Testing
- Mifepristone, Letrozole
- Where
- India
- Volunteers
- 120 people
- Sponsor
- Calcutta National Medical College and Hospital
Pregnancy
Telemedicine Medical Abortion Service Using the "No-test" Protocol in Ukraine and Uzbekistan.
The goal of this study is to pilot and evaluate a telemedicine medical abortion service delivery that allows remote communication between the woman and provider and limits medically unnecessary in-person visits to health or…
- Trial name
- NCT05028387
- Testing
- medical abortion
- Where
- 4 sites in Ukraine, Uzbekistan
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Second Trimester Medical Abortion
Paracervical Block During II-trimester Abortion
Paracervical blockage can reduce severe pain during second trimester induced medical abortion.
- Trial name
- NCT01617564
- Testing
- bipuvacain, NaCl
- Where
- 2 sites in Sweden
- Volunteers
- 112 people
- Sponsor
- Kristina Gemzell Danielsson
Abortion, Induced
Mifepristone and Misoprostol Versus Misoprostol Alone for Mid-trimester Termination of Pregnancy (14 - 21 Weeks LMP): A Randomized-controlled Double-blinded Trial
The primary goal of this study is to determine the clinical advantage of pre-treatment with mifepristone in second trimester misoprostol induction abortion.
- Trial name
- NCT00784186
- Testing
- mifepristone+misoprostol, misoprostol
- Where
- 2 sites in Vietnam
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Abortion, Legal
A Prospective Randomized Comparison Trial on the Use of Mifepristone With Sublingual or Buccal Misoprostol for Medical Abortions of Less Than 9 Weeks Gestation
The primary objective of this study is to compare the incidence of side effects of buccal and sublingual misoprostol when combined with mifepristone for medical abortions of less than 9 weeks gestation.
- Trial name
- NCT01156688
- Testing
- Misoprostol
- Where
- Hong Kong
- Volunteers
- 90 people
- Sponsor
- The University of Hong Kong
Early Pregnancy
Comparison of the Effectiveness of Treatment With Mifepristone and Misoprostol at the Same Time Compared to the Administration of Drugs at a 48-hour Interval for Medical Abortion.
Medical termination of pregnancy is a common and safe alternative to surgical termination of pregnancy(8). The current protocol in the investigators unit includes oral administration of Mifepristone 600 mg and oral Misoprostol…
- Trial name
- NCT03440866
- Testing
- Administration of drugs concomitantly.
- Where
- Israel
- Volunteers
- 250 people
- Sponsor
- HaEmek Medical Center, Israel
Pregnancy
Evaluation of Telemedicine Medical Abortion Service in Ecuador
This research seeks to demonstrate that a telemedicine model for the provision of legal abortion services in Ecuador is safe, feasible and acceptable to users requesting a medication abortion and who are less than 12 weeks…
- Trial name
- NCT06270056
- Testing
- Misoprostol
- Where
- 3 sites in Ecuador
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Medical Abortion
Treatment Regimens for Mifegyne and Cytotec
The purpose of this study is to test two regimens of mifegyne and cytotec for medical abortion. The investigators hypothesize that administration of both medications during one hospital visit will not compromise effectiveness.
- Trial name
- NCT00920465
- Testing
- mifegyne and cytotec
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Western Galilee Hospital-Nahariya
Pregnancy
Feasibility of Telemedicine Medical Abortion
This pilot study is designed to obtain data on the safety, acceptability, and feasibility of providing abortion by direct-to-patient telemedicine and mail.
- Trial name
- NCT04599725
- Testing
- medical abortion
- Where
- 15 sites in United States
- Volunteers
- 413 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Medical Termination of Pregnancy
Medical Termination of Pregnancy : Evaluation of Patients' Practices and Feelings in Brest Hospital
This study evaluate the feelings of patients about a medical termination of pregnancy that they experienced in Brest Hospital. Patients responded to an online questionnaire assessing their feelings at each stage of the medical…
- Trial name
- IMGEPR (NCT04294212)
- Where
- France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Abortion Early, Abortion in First Trimester
Using Telemedicine to Improve Early Medical Abortion at Home
The investigators plan a trial comparing telephone consultations for women requesting early medical abortion (EMA - under 10 weeks pregnant) to regular face-to-face consultations.
- Trial name
- UTAH (NCT04139382)
- Testing
- Telephone Consultation, Face-to-Face Consultation
- Where
- United Kingdom
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- NHS Lothian
Medical Abortion, Fetus
Reducing the Need for In-Clinic Follow-Up for Medical Abortion in Moldova and Uzbekistan
The purpose of this study is to determine whether an alternative method of follow-up after medical abortion is acceptable and feasible for use in Moldova and Uzbekistan.
- Trial name
- NCT01410266
- Testing
- Alternative follow-up
- Where
- 7 sites in Moldova, Uzbekistan
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Medical; Abortion, Fetus
Comparison of Rate of Complete Abortion Between Letrozole Plus Misoprostol vs Misoprostol Alone
Comparison of rate of complete abortion between Letrozole plus Misoprostol versus Misoprostol alone in first trimester pregnancy
- Trial name
- NCT05940233
- Testing
- Letrozole
- Where
- Thailand
- Volunteers
- 70 people
- Sponsor
- Queen Savang Vadhana Memorial Hospital, Thailand
Abortion, Induced
Mifepristone and Misoprostol Versus Misoprostol Alone for Mid-trimester Termination of Pregnancy (14-21 Weeks LMP)
The primary goal of this study is to determine the clinical advantage of pre-treatment with mifepristone in second trimester misoprostol induction abortion.
- Trial name
- NCT00957346
- Testing
- Mifepristone+misoprostol
- Where
- Puerto Rico
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
IUC Insertion After Medical Abortion
Intrauterine Contraception (IUC) After Medical Abortion
Today a large proportion of early abortions are medical, in accordance to the woman's choice. The main objective of the present study was to compare, in a randomised fashion, initiation of intrauterine contraception (IUC) at…
- Trial name
- NCT01537562
- Testing
- Timing of IUC insertion
- Where
- Sweden
- Volunteers
- 129 people
- Sponsor
- Karolinska Institutet
Acute Pain
Prophylactic Pregabalin to Decrease Pain During Medical Abortion
Medical abortion has been associated with significant pain. The objective of this trial is to determine whether one dose of pregabalin 300 mg, given during medical abortion in addition to the standard of care analgesics, will…
- Trial name
- NCT02782169
- Testing
- Pregabalin
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of Hawaii