Clinical trials: Mechanical Ventilation Strategies
Acute Kidney Failure, Mechanical Ventilation Strategies
Driving Pressure Optimization, RV-PA Coupling, and AKI in Mechanically Ventilated Critically Ill Patients
This study evaluates the effect of driving pressure optimization on right ventricular-pulmonary artery (RV-PA) coupling, assessed by TAPSE/PASP ratio, and its association with acute kidney injury (AKI) progression in mechanically…
- Conditions
- Acute Kidney Failure, Mechanical Ventilation Strategies, Right Ventricular (RV) Dysfunction, Critical Illness
- Trial name
- NCT07836387
- Testing
- Driving Pressure-Guided Ventilator Optimization
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Nardin Aymn Boshra
Acute Respiratory Insufficiency
Ventilation Strategies During Spontaneous Breathing Trial
Patients who are intubated and mechanically ventilated for acute respiratory failure in the Intensive Care Unit (ICU) are at some point eligible for weaning.
- Trial name
- WEANING (NCT02939963)
- Testing
- ATC then pressure support 7 cm H2O PEP 4 cm H2O, Pressure support 7 cm H2O PEP 4 cm H2O then ATC
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Hospices Civils de Lyon
Adult, Guideline Adherence
Adherence to LPV in SICU and Associated Clinical Outcomes
Lung Protective Ventilation strategy (LPV) with low tidal volume and adequate positive end-expiratory pressure is recommended for not only patients with acute respiratory distress syndrome (ARDS) but also those without ARDS too.
- Conditions
- Adult, Guideline Adherence, Humans, Intensive Care Units
- Trial name
- NCT03698799
- Where
- Thailand
- Volunteers
- 306 people
- Sponsor
- Mahidol University
ARDS (Acute Respiratory Distress Syndrome), Electrical Impedance Tomography (EIT)
Comparison of Different PEEP Titration Strategies Using Electrical Impedance Tomography in Patients With ARDS
The aim of the this study is to assess the short term physiological effects of 3 ventilation strategies for adult patients with ARDS admitted to intensive care unit.
- Conditions
- ARDS (Acute Respiratory Distress Syndrome), Electrical Impedance Tomography (EIT), Positive End Expiratory Pressure (PEEP), Acute Lung Injury
- Trial name
- DELTA (NCT04247477)
- Testing
- Ventilation strategy
- Where
- France
- Volunteers
- 22 people
- Sponsor
- University Hospital, Angers
Mechanical Ventilation
Protective Ventilatory Strategy in Potential Organ Donors
The aim of the study is to verify if a "PROTECTIVE" ventilatory strategy (low tidal volume and high PEEP, application of CPAP during the apnea test and recruitment maneuvers), improves lung function and increases the number of…
- Trial name
- NCT00260676
- Testing
- change ventilation
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- University of Turin, Italy
Mechanical Ventilation, Acute Respiratory Distress Syndrome
ART-3 Pilot - Driving Pressure Limited Ventilation for Patients Without ARDS (ART3pilot)
This is a multicenter randomized controlled pilot trial to investigate the feasibility of a driving pressure limited mechanical ventilation strategy compared to a conventional strategy in patients without acute respiratory…
- Trial name
- ART-3pilot (NCT02376647)
- Testing
- Driving pressure limited ventilation, Conventional ventilation
- Where
- Brazil
- Sponsor
- Hospital do Coracao
Mechanical Ventilation, Acute Respiratory Failure
FRC Guided Therapy in Acute Respiratory Failure
In ventilated patients with acute respiratory failure endotracheal suctioning may lead to alveolar derecruitment, which can be monitored by means of functional residual capacity (FRC) measurements.
- Conditions
- Mechanical Ventilation, Acute Respiratory Failure, Cardiac Surgery
- Trial name
- NCT01280019
- Testing
- alveolar recruitment manoeuvre
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University of Luebeck