Clinical trials: Mature Teeth
Regenerative Endodontic Treatment, Cleaning and Shaping Only With Proper Coronal Seal
Outcomes of Conventional Root Canal Treatment Compared to Regenerative Endodontics, and Cleaning and Shaping Only in Mature Upper First Premolars
It was to compare clinically between the success of the primary endodontic treatment, regeneration, and only cleaning and shaping in necrotic mature first premolars with apical periodontitis
- Conditions
- Regenerative Endodontic Treatment, Cleaning and Shaping Only With Proper Coronal Seal, Necrotic Mature First Premolar
- Trial name
- NCT07609732
- Testing
- cell homing, Cleaning and shaping only
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pulpitis, Pulp Exposure, Dental
Pulpotomy in Carious Permanent Mature Teeth: Pulp Survival and Risk Factors
This Trial evaluated the extent of pulp survival following pulpotomy in the permanent tooth pulp exposed by caries and identify potential risk factors for pulpal complications.
- Conditions
- Pulpitis, Pulp Exposure, Dental, Pulp and Periapical Tissue Disease
- Trial name
- NCT03490422
- Testing
- Pulpotomy
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- National University Health System, Singapore
Pulpitis
Evaluation of Pulpotomy Using Two Different Agents in Mature Anterior Teeth With Pulpitis
the study will evaluate the clinical and radiological success of mature permanent anterior teeth pulpotomy in children and adolescents with signs of pulpitis using two different Biomimetic materials (NeoPutty® and Biodentine™) as…
- Trial name
- NCT06468085
- Testing
- premixed Bioceramic NeoPUTTY®, Biodentine™, Root canal treatment
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Irreversible Pulpitis
Evaluation of Two Different Calcium Silicate Cements as a Treatment for Irreversible Pulpitis in Mature Molars
This randomized controlled clinical trial aims to evaluate the effect of two calcium silicate cements-Biodentine and EndoCem-on post-operative pain and treatment success in vital pulp therapy (VPT) for mature permanent mandibular…
- Trial name
- NCT07066410
- Testing
- intervention 1: endocem, Intervention 1: biodentine
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Irreversible Pulpitis, Mature Teeth
Effectiveness of Pulpotomy in the Management of Mature Permanent Tooth With Irreversible Pulpits
This study is to evaluate the effectiveness of pulpotomy in mature permanent tooth with irreversible pulpits, and compare the clinical efficacy of pulpotomy and root canal therapy.
- Trial name
- NCT05622266
- Testing
- Pulpotomy, Root Canal Therapy
- Where
- China
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Post-operative Pain
Using Three Different Final Irrigants and Showing Their Effects on the Success of Revascularization
this study will assess different irrigating materials on the success revascularization of necrotic mature teeth associated with PRF.
- Trial name
- NCT03591172
- Testing
- Propolis, Nano-propolis, saline
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Cairo University
Drug Effect
Evaluation of Antibacterial Effect of Allium Sativum, Calcium Hydroxide and Their Combination in Infected Mature Teeth
This study was to evaluate and compare garlic extract antibacterial effect when used as an intra-canal medicament in infected mature anterior teeth with calcium hydroxide and a mixture of calcium hydroxide and garlic, using real…
- Trial name
- Garlic (NCT05050071)
- Testing
- Allium Sativum, Polymerase chain reaction
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Maturation of the Midpalatal Suture and Maxillary Third Molar Mineralization in Healthy Individuals
Correlation Between the Midpalatal Suture Maturity and the Maxillary Third Molar Mineralization: a CBCT Study
Assessing the maturation of the mid-palatal suture is an essential criterion for orthodontic decision-making. However, from a CBCT according to Angelieri's classification , it remains difficult for the practitioner's untrained…
- Trial name
- NCT07181707
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Carious Teeth
The Effect of Cryotherapy on Treatment Outcomes for Pulpotomy
The goal of this clinical trial is to investigate the effect of cryotherapy on treatment outcome for pulpotomny in permanent mature carious posterior teeth.
- Trial name
- NCT07303010
- Testing
- Addition of Cryotherapy on pulpotomy
- Where
- Thailand
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Sirawut Hiran-us
Dental Pulp Capping, Dental Caries Extending to Pulp
Long-term Evaluation of Direct Pulp Capping
Calcium hydroxide and mineral trioxide aggregate have been used in vital pulp therapy with variable outcomes recorded by different study.
- Trial name
- NCT03403985
- Testing
- Calcium Hydroxide (Ca(OH)2), Mineral Trioxide Aggregate
- Where
- Jordan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Apical Periodontitis
Different Treatment Options For Mature Teeth With Apical Periodontitis
A randomized control trial which aim to compare the healing potential for the following treatment options for mature teeth with apical periodontitis: Group I: Conventional root canal treatment (CRT) Group II: Regenerative…
- Trial name
- NCT07700394
- Testing
- root canal treatment and intracanal medicament, Regeneration, Regeneration with BMPs
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sara Tariq Elemam
Irreversible Pulpitis, Partial Pulpotomy
Evaluation of Hemostasis Time on Partial Pulpotomy in Teeth With Clinical Signs Indicative of Irreversible Pulpitis
The aim of this prospective study is to investigate the influence of time taken to achieve hemostasis on outcome of partial pulpotomy in teeth with clinical signs indicative of irreversible pulpitis. OBJECTIVE:- 1.
- Trial name
- NCT06768567
- Testing
- effect of hemostasis time on outcome of partial pulpotomy in teeth with clinical signs indicative of irreversible pulpitis.
- Where
- India
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Periapical Periodontitis
Effect of Injectable Platelet Rich Fibrin Augmented With Vitamin C Compared to Injectable Platelet Rich Fibrin Alone on Healing of Necrotic Mature Single Rooted Teeth With Chronic Peri-apical Periodontitis Following Regenerative Endodontics (A Randomized Controlled Trial)
The purpose of the study is to investigate the effect of injectable platelet rich fibrin augmented with Vitamin C (ascorbic acid) in healing of chronic peri-apical lesion, by assessing it radiographically 2dimensionally and 3…
- Trial name
- NCT05585359
- Testing
- injectable platelet rich fibrin augmented with Vitamin C
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Apical Periodontitis
Assessment of Different Disinfection Protocols on Regenerative Potential of Mature Teeth
Regenerative endodontic procedures have been used to successfully treat human mature permanent teeth with necrotic pulps and apical periodontitis.
- Trial name
- NCT05557994
- Testing
- Method
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Minia University
Deep Caries
Deep Caries in Mature Teeth With Reversible Pulpitis
This clinical trial will be conducted to clinical, radiographical and histological evaluation of pulp condition with reversible pulpities after total and selective removal of primary and secondary caries (randomized clinical…
- Trial name
- NCT07028905
- Testing
- Total caries removal, Partial caries removal
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Minia University
Irreversible Pulpitis
Partial Pulpotomy in Mature Permanent Teeth With Signs and Symptoms of Irreversible Pulpits
The main purpose of the present study is to assess the outcome of partial pulpotomy by using two different bioactive materials, namely MTA [MTA Angelus (Angelus, Londrina, Brazil) and Total Fill BC putty (FKG, La Chaux-de-Fonds…
- Trial name
- NCT04870398
- Testing
- Vital Pulp therapy-Partial pulpotomy
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Pulpitis - Irreversible
A-prf,Nanochitosan Combined With A-prf Compared to Chitosan for Symptomatic Irreversible Pulpitis of Mature Teeth
Clinical and radiographic assessment of A-prf,A-prf combined with nanochitosan compared to chitosan for symptomatic irreversible pulpits in lower permanent first molar
- Trial name
- NCT06438523
- Testing
- PULPOTOMY OF MATURE PERMENANT TEETH
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Pulpitis
MMP-9 Expression in Permanent Mature Teeth With Symptomatic Pulpitis
Matrix metallopeptidase-9 (MMP-9) expression was compared in healthy and inflamed pulp and the outcome of coronal pulpotomy in teeth with symptomatic pulpitis was assessed.
- Trial name
- NCT03807674
- Testing
- Coronal pulpotomy
- Where
- Lithuania
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Eglė Gvazdaitytė
Pulpitis - Irreversible
Assessing Success of MTA and Pre-mixed Bioceramic in Mature Teeth With Irreversible Pulpitis With Full Pulpotomy.
Although many pulpotomy agents are commercially available, there is a dearth of clinical research comparing the efficacy of these agents in treating individuals with irreversible pulpitis.
- Trial name
- GCP (NCT05853185)
- Testing
- Pro Root MTA®, EBRRM®
- Where
- Pakistan
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Liaquat University of Medical & Health Sciences
Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1
Baby Detect : Genomic Newborn Screening
Newborn screening (NBS) is a global initiative of systematic testing at birth to identify babies with pre-defined severe but treatable conditions.
- Conditions
- Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1, Phosphoglucomutase 1 Deficiency, Maturity Onset Diabetes of the Young
- Trial name
- BabyDetect (NCT05687474)
- Where
- Belgium
- Volunteers
- 6,824 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Liege