Clinical trials: Maternal Complications, open to volunteers
Maternal Complications, Pregnancy Complication
Pregnancy Surveillance Program of Patients Exposed to Epidiolex/Epidyolex During Pregnancy
The purpose of this study is to evaluate pregnancy-related health outcomes in participants who are exposed to Epidiolex/Epidyolex during pregnancy and their infant up to 12 months of life.
- Conditions
- Maternal Complications, Pregnancy Complication, Birth Outcomes, Adverse, Pregnancy
- Trial name
- NCT06113237
- Testing
- Epidiolex
- Where
- 3 sites in United States, Germany and 1 more
- Volunteers
- 50 people
- Sponsor
- Jazz Pharmaceuticals
Pregnancy, Post Partum
Deconstructing Maternal Burdens: Doulas and the Community Unite for Health
This study is a randomized controlled trial comparing two models of doula support for pregnant individuals enrolled in Medicaid: an enhanced doula support model, in which support starts earlier in pregnancy, occurs more…
- Conditions
- Pregnancy, Post Partum, Doula Care, Postpartum Depression (PPD)
- Trial name
- UNITE (NCT07799805)
- Testing
- Doula, Standard (non-enhanced) Medicaid doula support
- Where
- United States
- Volunteers
- 516 people
- Sponsor
- University of Florida
Maternal Health, Child Health
Boston Birth Cohort Study
Early life exposures may lead to adverse effects on health in later life. The Boston birth Cohort study is designed to study a broad array of early life factors and their effects on maternal and child health outcomes across the…
- Conditions
- Maternal Health, Child Health, Pregnancy Complications, Birth Outcome, Adverse
- Trial name
- NCT03228875
- Where
- United States
- Volunteers
- 24,000 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Postpartum Complication
IMPACT: Improving Maternal Postpartum Access to Care Through Telemedicine
The purpose of this study is to compare two complex, multi-component evidence-based postpartum interventions in underserved populations of lower socioeconomic status in an effort to reduce maternal morbidity and mortality.
- Trial name
- IMPACT (NCT06218355)
- Testing
- Intensive Education, Enhanced Virtual Care
- Where
- 2 sites in United States
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Pregnancy Complications, Maternal Distress
Providing an Optimized and Empowered Pregnancy for You (POPPY) Aim 3: Randomized Controlled Trial
The PᵌOPPY study is designed to support the American Heart Association's mission to improve maternal/infant health outcomes and address inequities in maternal/infant health care.
- Conditions
- Pregnancy Complications, Maternal Distress, Adverse Birth Outcomes, Infant Conditions
- Trial name
- P3OPPY (NCT06510075)
- Testing
- Digital Health intervention, Community Health Worker, Digital Health Intervention plus Community Health Worker
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- University of Alabama at Birmingham
Pregnancy Complication, Aortic Dissection
PregnAncy-Related Aortic DISsEction in China
A multicenter observational study on pregnancy-related aortic dissection
- Conditions
- Pregnancy Complication, Aortic Dissection, Marfan Syndrome, Loeys-Dietz Syndrome
- Trial name
- PARADISE (NCT07672210)
- Testing
- Intervention strategies including medication or surgery
- Where
- 4 sites in China
- Volunteers
- 500 people
- Sponsor
- DeltaHealth Hospital · Shanghai
Hemophilia A, Hemophilia A, Severe
Hemophilia A Research Program
This study longitudinally observes the intergenerational (mother-child) continuum in hemophilia A from pregnancy through early childhood.
- Conditions
- Hemophilia A, Hemophilia A, Severe, Factor VIII (FVIII), FVIII Deficiency
- Trial name
- HARP (NCT07414511)
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Washington
Postpartum Complication, Maternal Hypertension
Safest Choice of Antihypertensive Regimen for Postpartum Hypertension
The purpose of this investigator-initiated randomized control trial is to determine whether oral Nifedipine versus oral Labetalol is superior in controlling high blood pressures in the postpartum period.
- Conditions
- Postpartum Complication, Maternal Hypertension, High Blood Pressure
- Trial name
- SCARPH (NCT05551104)
- Testing
- Oral Nifedipine, Oral Labetalol
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Loma Linda University
Maternal Sepsis, Infections
EnCoRe MoMS: Engaging Communities to Reduce Morbidity From Maternal Sepsis (Aim 1)
Sepsis is the second leading cause of maternal death in the U.S. Labor and postpartum are particularly vulnerable risk periods. The goal of this multi-center, multidisciplinary study is to evaluate a maternal sepsis safety bundle.
- Trial name
- NCT06145724
- Testing
- Maternal Sepsis Safety Bundle
- Where
- 4 sites in United States
- Volunteers
- 33,183 people, healthy volunteers welcome
- Sponsor
- Columbia University
Maternal Sepsis, Infections
EnCoRe MoMS: Engaging Communities to Reduce Morbidity From Maternal Sepsis (Aim 2)
Sepsis is the second leading cause of maternal death in the U.S. For racial and ethnic minoritized birthing people, especially those who are Black, living in poverty, and from underserved communities, labor and postpartum are…
- Trial name
- NCT06148532
- Where
- United States
- Volunteers
- 400,000 people
- Sponsor
- Columbia University
Maternal Sepsis, Infections
EnCoRe MoMS: Engaging Communities to Reduce Morbidity From Maternal Sepsis (Aim 3)
Sepsis is the second leading cause of maternal death in the U.S. For racial and ethnic minoritized birthing people, especially those who are Black, living in poverty, and from underserved communities, labor and postpartum are…
- Trial name
- NCT06160349
- Where
- 3 sites in United States
- Volunteers
- 200 people
- Sponsor
- Columbia University
Sarcopenia, Gestational Diabetes Mellitus (GDM)
Sarcopenia in Gestational Diabetes
Sarcopenia is a syndrome characterized by loss of skeletal muscle mass and strength, and physical performance deterioration. Prevalence of sarcopenia in elderly people is remarkably high (prevalence of about 25% in 60+ years…
- Conditions
- Sarcopenia, Gestational Diabetes Mellitus (GDM), Pregnancy Complications, Adverse Maternal and Neonatal Outcomes
- Trial name
- SiGnal-D (NCT06876090)
- Testing
- Sarcopenia tests (for muscle mass, muscle function, physical performance), Oral Glucose Tolerance Test, Montreal Cognitive Assessment
- Where
- 3 sites in Austria, Italy
- Volunteers
- 200 people
- Sponsor
- Istituto di Neuroscienze Consiglio Nazionale delle Ricerche
Maternal Health Services, Infant, Newborn
Comparing Integrative Midwife-led vs. Fragmented Inpatient Postpartum Care: Impact on Satisfaction and Transition to Motherhood
The goal of this clinical trial is to compare two different forms of postnatal care to find out which is most beneficial for mothers and their children after birth and with which they are most satisfied.
- Conditions
- Maternal Health Services, Infant, Newborn, Postnatal Care, Breast Feeding
- Trial name
- SMILE (NCT07077941)
- Testing
- Integrative care
- Where
- Austria
- Volunteers
- 784 people
- Sponsor
- Medical University of Vienna
Delivery Complication, Delivery Problem
Delivery Outcomes by AIDA (Artificial Intelligence Dystocia Algorithm) Analysis
Aims: Primary aim is to investigate outcomes of eutocic labor, evaluating intrapartum ultrasound parameters by AIDA method: Angle of progression (AoP), Asynclitism degree (AD), fetal head-symphysis distance (HSD), and midline…
- Conditions
- Delivery Complication, Delivery Problem, Delivery; Injury, Delivery; Injury, Maternal
- Trial name
- AIDA (NCT06664112)
- Testing
- AIDA Analysis
- Where
- 2 sites in Italy
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Centro di Ricerca Clinica Salentino
Maternal Outcomes, Newborn Complication
Effectiveness of Upright vs. Lithotomy Birthing Position on Maternal and Newborn Outcomes
This study investigates the effectiveness of upright versus lithotomy birthing positions on maternal and newborn outcomes. Conducted at the Maternity Teaching Hospital in Erbil City, it employs a quasi-experimental design with 62…
- Trial name
- NCT06670235
- Testing
- Upright Birthing Position, Lithotomy Birthing Position
- Where
- Iraq
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Hawler Medical University
Preeclampsia, Eclampsia
The Preeclampsia Registry
The purpose of The Preeclampsia Registry is to collect and store medical and other information from women who have been medically diagnosed with preeclampsia or a related hypertensive (high blood pressure) disorder of pregnancy…
- Conditions
- Preeclampsia, Eclampsia, HELLP Syndrome, Toxemia
- Trial name
- TPR (NCT06377878)
- Where
- United States
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Preeclampsia Foundation
Pregnancy in Diabetic, Type 1 Diabetes
Danish Diabetes Birth Registry 2
Pregnancies in women with pre-existing diabetes are considered "high risk" pregnancies, poses daily clinical challenges and in terms of research - a number of unanswered questions.
- Conditions
- Pregnancy in Diabetic, Type 1 Diabetes, Type 2 Diabetes, Parents
- Trial name
- DDBR2 (NCT05678543)
- Where
- 4 sites in Denmark
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Stillbirth, Obstetric Complication
Improving Intrapartum Care for Saving Life at Birth in Ethiopia Through PartoMa Approach
Overall Objective To introduce PartoMa approach (locally agreed and achievable intrapartum guidelines and a continual in-house training program) to Ethiopian context through continuous fetal heart rate (FHR) monitoring using MOYO…
- Conditions
- Stillbirth, Obstetric Complication, Maternal Death, Perinatal Death
- Trial name
- PartoMa-Eth (NCT06273007)
- Testing
- PartoMa intervention(Locally achievable intrapartum care guideline), in house LDHF trainings
- Where
- 2 sites in Ethiopia
- Volunteers
- 500 people
- Sponsor
- Haramaya Unversity
Twin; Complicating Pregnancy, Advanced Maternal Age Pregnancy
Birth Cohort Study of China Medical University
The CMUBCS is a birth cohort study located in Shenyang, China. Its initial aim is to facilitate research on understanding the interplay between genes and environmental factors on disease etiology.
- Conditions
- Twin; Complicating Pregnancy, Advanced Maternal Age Pregnancy, Scarred Uterus, Overweight and Obesity
- Trial name
- NCT03561766
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital