Clinical trials: Mastication Disorder, open to volunteers
Nutritional and Metabolic Diseases, Overweight
The FaibaGo Study - Long-Term Weight Reduction Via Low-Threshold Intervention
The main aim of this study is to assess the effect of a chewing gum containing galactooligosaccharides (GOS) on the body mass index (BMI), the metabolism and the oral and intestinal microbiomes in a population of overweight…
- Trial name
- NCT07036692
- Testing
- FibreGum
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- University of Bern
Schizophrenia Disorder
AI-assisted Masticatory Muscle Training in Patients With Schizophrenia
Dysphagia seems to be quite common and potentially severe in schizophrenia, which may lead to acute asphyxia or pneumonia. Dysphagia in schizophrenia could be associated with drug-induced Parkinsonism, dystonia, tardive…
- Trial name
- AI-assisted (NCT07154407)
- Testing
- AI-assisted Mastisting Training App
- Volunteers
- 100 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Periodontitis
Occlusal Force and Chewing After Periodontal Therapy
Stage III and Stage IV periodontitis are associated with loss of periodontal support, tooth mobility, and impaired oral function, which may affect occlusal force distribution and chewing performance.
- Trial name
- NCT07772115
- Testing
- Non-Surgical Periodontal Therapy
- Volunteers
- 30 people
- Sponsor
- Mohammed Bin Rashid University of Medicine and Health Sciences
Colorectal Cancer (CRC)
Trial of Gum Chewing to Enhance the Restoration of Intestinal Motility in Colorectal Cancer Surgery
Surgery is one of the most frequent treatments of colorectal cancer. However, delayed restoration of intestinal motility is a common phenomenon in patients who undergo colorectal surgery, and may reduce comfort, prevent the early…
- Trial name
- NCT06860685
- Testing
- gum chewing
- Where
- China
- Volunteers
- 292 people
- Sponsor
- Sichuan Cancer Hospital and Research Institute
Vertigo Benign Positional, Dizziness
The Effect of Chewing Gum on Dizziness in Patients Diagnosed With Posterior Canal Benign Paroxysmal Positional Vertigo in the Emergency Department
Dizziness is a common reason for emergency department visits. Posterior canal benign paroxysmal positional vertigo (BPPV) is one of the most frequent causes of peripheral vertigo.
- Trial name
- NCT07749573
- Testing
- Dimenhydrinate, Sugar-Free Mint-Flavored Chewing Gum
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Pain, Anxiety
Effects of Music Application and Gum Chewing on Pain, Anxiety, and Patient Satisfaction During Episiotomy Repair
Lacerations and episiotomies are serious procedures requiring surgical stitches. Therefore, pain occurs during episiotomy repair. Pain during episiotomy repair also causes anxiety, which in turn exacerbates pain.
- Conditions
- Pain, Anxiety, Patient Satisfaction
- Trial name
- NCT07323758
- Testing
- Music, Gum Chewing
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Osteopenia, Osteoporosis
Calcium-Rich Food Versus Calcium Carbonate for Bone Health
This study will compare adherence, tolerability, safety, and treatment satisfaction between a calcium-rich food and a traditional calcium carbonate supplement in women ages 40 to 90 who are at increased risk for osteoporosis.
- Conditions
- Osteopenia, Osteoporosis, Bone Health in Perimenopausal Women, Menopause Related Conditions
- Trial name
- NCT07763509
- Testing
- 500 mg calcium from milk-derived minerals, Calcium Carbonate 500 MG
- Where
- United States
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Cornell University
Pain Management, Fear
Distraction Methods for Reducing Pain and Fear During Blood Draw in Children
Blood draw is a common invasive procedure that can cause pain and fear in children. This randomized controlled trial aims to compare the effects of pinwheel blowing, 3D hologram viewing, and sugar-free gum chewing on pain and…
- Trial name
- PED-DISTRACT (NCT07770191)
- Testing
- 3D Hologram Viewing, Pinwheel Blowing, Gum Chewing
- Where
- Turkey (Türkiye)
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Gülsev Kutman
Preterm Birth, Low Birthweight Neonate
Xylitol and the Prevention of Periodontal Disease and Preterm Birth Trial
The ground-breaking Prevention of Prematurity and Xylitol (PPaX) cluster randomized controlled clinical trial was conducted in Lilongwe, Malawi and enrolled approximately 10,069 pregnant individuals seeking to evaluate the impact…
- Conditions
- Preterm Birth, Low Birthweight Neonate, Periodontitis, Gingivitis
- Trial name
- XaPPP (NCT07424846)
- Testing
- Xylitol Chewing gum, Sorbitol chewing gum
- Where
- Malawi
- Volunteers
- 6,000 people
- Sponsor
- University of Washington
Endodontically Treated Teeth
Bite Force and Occlusal Force Distribution Following Root Canal Treatment.
Understanding the changes in bite force and occlusal force distribution in ETT is clinically important, as it can directly influence tooth prognosis, guide restorative treatment planning, and impact the long-term survival of the…
- Trial name
- B-FORCE RCT (NCT07626372)
- Where
- Thailand
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Tobacco Use Cessation, Tobacco Use
Reach Through Equitable Implementation in Utah
The goal of this pragmatic, multilevel Type III Hybrid Effectiveness-Implementation trial is to increase the reach of existing evidence-based interventions (EBIs) for tobacco cessation and to mitigate the impact of adverse Social…
- Conditions
- Tobacco Use Cessation, Tobacco Use, Tobacco Smoking, Tobacco Chewing
- Trial name
- REI-UT (NCT06881069)
- Testing
- Clinic Level: AAC - SDOH, AAC - Tobacco, Non-Bundled, Bundled
- Where
- United States
- Volunteers
- 1,560 people
- Sponsor
- University of Utah
Mild Cognitive Impairment (MCI), Aging
Elderberry Functional Gum and Cognitive & Oral Health in Older Adults
Globally, the aging population is increasing rapidly, leading to a dramatic rise in the prevalence of Alzheimer's disease and other types of dementia.
- Conditions
- Mild Cognitive Impairment (MCI), Aging, Oral Microbiome
- Trial name
- NCT07054645
- Testing
- Elderberry Anthocyanin Chewing Gum
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Burdur Mehmet Akif Ersoy University
Face
Effects of Hard Gum Chewing on Facial Soft Tissue Morphology
This pilot clinical trial will evaluate whether intentional chewing of a standardized hard chewing gum for 4 weeks produces measurable changes in facial morphology in healthy adults.
- Trial name
- GUM-3D (NCT07726511)
- Testing
- Hard Gum Chewing
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- UConn Health
Molar-Incisor Hypomineralization (MIH), Masticatory Performance
Evaluation of Occlusal Force and Masticatory Function in Children With Molar-Incisor Hypomineralization
This study aims to evaluate right-left chewing balance and masticatory function in children with Molar-Incisor Hypomineralization (MIH) before and after restorative treatment.
- Conditions
- Molar-Incisor Hypomineralization (MIH), Masticatory Performance, Occlusal Analysis, Chewing Function
- Trial name
- NCT07589179
- Testing
- Glass Hybrid Restorative Treatment
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Marmara University
Malocclusion
Comparison of Acupressure, Ibuprofen, and Chewing Gum for the Management of Post-Archwire Orthodontic Pain
The goal of this clinical trial is to find out which method works best to reduce pain after braces are adjusted for the first time (when the first archwire is placed).
- Trial name
- NCT07638644
- Testing
- Acupressure, Ibuprofen 400 mg (if necessary), Chewing Gum
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Bahria University
TMD/Orofacial Pain, Myalgia of Mastication Muscle
Botulinum Toxin in the Management of Temporo-mandibular Related Myalgia: a Prospective Study
The aim of this study was to evaluate the clinical course in terms of pain, function and quality of life of patients with TMD-related myalgia during six months after receiving BTX-A injections.
- Conditions
- TMD/Orofacial Pain, Myalgia of Mastication Muscle, Botulinum Toxin, Type a
- Trial name
- BOMAMY (NCT06677216)
- Testing
- Botulinum Toxin, Type A
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Diakonessenhuis, Utrecht
Hypersialorrhea (Excessive Salivation), Psychiatric Disorders
Chewing Gum as a Therapeutic Intervention for the Management of Hypersalivation
Psychiatric disorders often require specific treatments, usually involving medications called psychotropic drugs. While effective, these medications can cause significant side effects.
- Trial name
- Chew Daily (NCT07158359)
- Testing
- chewing gum mastication
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Cadillac
Edentulism Complete, Denture, Complete
Nutritional Intervention for Older Adults With Complete Dentures
The purpose of this clinical trial is to test a nutritional intervention. This study helps older adults who wear complete removable dentures improve their health.
- Conditions
- Edentulism Complete, Denture, Complete, Mastication Disorder
- Trial name
- NCT07692828
- Testing
- Nutritional Intervention
- Where
- Chile
- Volunteers
- 40 people
- Sponsor
- Universidad de La Frontera
Systemic Sclerosis (SSc), Scleroderma
Patients Diagnosed With Scleroderma and Their Chewing and Swallowing Performance
It is recommended to focus on the physical functionality, chewing, and swallowing performance of individuals diagnosed with scleroderma.
- Conditions
- Systemic Sclerosis (SSc), Scleroderma, Scleroderma (Limited and Diffuse), Scleroderma, Localized
- Trial name
- NCT07182981
- Testing
- Questionnaire application for child and adult scleroderma patients
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Hacettepe University
Type 2 Diabetes
Effect of Molar Replacement on Glycemic Control in Adults With Uncontrolled Type 2 Diabetes
Type 2 diabetes (T2D) is a major global health issue, affecting about 9.2% of adults in Europe. Although treatment begins with lifestyle changes and medications, up to half of patients fail to achieve adequate blood sugar…
- Trial name
- DIABETEETH (NCT07666529)
- Testing
- Replacement of one pair of molars
- Volunteers
- 140 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris