Clinical trials: Mastication Disorder
Dysphagia
Chewing and Oral Processing of Solid Food
Food texture modification is commonly used as an intervention for people with dysphagia (swallowing impairment). However, the field currently lacks a proper understanding of how this intervention works.
- Trial name
- NIH_HVX6 (NCT05594173)
- Testing
- Food texture modification
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Molar Hypomineralization, Incisor
Orofacial Functions in Individuals With and Without Molar Incisor Hypomineralization
Molar incisor hypomineralization (MIH) is a qualitative developmental defect of the enamel with a complex, multifactorial nature and a significant genetic component that predominantly affects the permanent first molars and…
- Trial name
- NCT06692257
- Testing
- Observation
- Where
- Brazil
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Mouth, Edentulous
Evaluation of Chewing Efficiency of Conventional Complete Denture in Comparison to Reinforced Poly Amide Denture
the trial is done in order to reinforce polyamide to improve its modulus of elasticity to be able to use it as a denture base material in all clinical cases
- Trial name
- NCT03391063
- Testing
- polyamide, heat cured acrylic resin
- Volunteers
- 38 people
- Sponsor
- Cairo University
Stroke
The Impact of Chewing Food on Stroke Patients
The goal of this clinical trial is to explore the effect of Chewing Food on quality of life and nutritional status in ischemic stroke patients.
- Trial name
- NCT06637033
- Testing
- Chewing Real Food, routine rehabilitation therapy, Oral tube feeding
- Where
- 2 sites in China
- Volunteers
- 120 people
- Sponsor
- Zeng Xi
Nutritional and Metabolic Diseases, Overweight
The FaibaGo Study - Long-Term Weight Reduction Via Low-Threshold Intervention
The main aim of this study is to assess the effect of a chewing gum containing galactooligosaccharides (GOS) on the body mass index (BMI), the metabolism and the oral and intestinal microbiomes in a population of overweight…
- Trial name
- NCT07036692
- Testing
- FibreGum
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- University of Bern
Bowel Ileus, Flatus
Chewing Gum on Postoperative Ileus in Children
Traditional postoperative care has been challenged recently to improve and speedup recovery (including the return of bowel function) such that patients can be discharged to home more quickly.
- Trial name
- GUM_1 (NCT03666377)
- Testing
- Gum chewing
- Where
- Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Malocclusion, Dementia
Oral Health for Healthy Cognitive Aging
Oral health is a critical factor of systemic health, although usually forgotten. A potential relation between cognitive deficits and oral diseases has been suggested.
- Trial name
- SOECS (NCT02986386)
- Testing
- Dental occlusion restoration, Orthodontic treatment of malocclusion
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Universidad de Granada
Aging, Cognitive Decline
Intermittent Energy Restriction and Chewing on Neural Stem Cell Ageing and Adult Hippocampal Neurogenesis Associated Cognition
Extended bouts of periodic mastication and intermittent energy restriction (IER) may improve cognitive performance in the context of adult hippocampal neurogenesis in an ageing population.
- Trial name
- ChANgE (NCT03457870)
- Testing
- Intermittent Energy Restriction, Chewing, Chewing + Intermittent Energy Restriction
- Where
- United Kingdom
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- King's College London
Biting, Chewing Problem
Biting Force and Chewing Efficiency of Complete Dentures.
The aim of this study was to compare the MBF and chewing efficiency of complete denture bases fabricated by conventional, 3D printing and milling techniques.
- Trial name
- NCT04793503
- Testing
- conventional complete denture, CADCAM 3D printed denture, CAD/CAM milled denture
- Where
- Egypt
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Evaluate the Association Between Certain Environmental Exposures (e.g. Cigarette Smoking, Alcohol Drinking, Betel Nut Chewing…) and Head and Neck Cancers, Assess the Effect of Genetic Factors, Including Both SNP and Copy Number Variation (CNV) Through Analysis of Both Main Effect and Gene-gene Interaction
International Cancer of the Head and Neck, Genetics and Environment (InterCHANGE) Study
Our overall objective is to understand the role of lifestyle factors, genetics and HPV infection in the development and prognosis of head and neck cancer particularly in Asia.
- Trial name
- InterCHANGE (NCT01972802)
- Where
- Taiwan
- Volunteers
- 900 people
- Sponsor
- National Taiwan University Hospital
Gynecologic Disease
Preoperative Chewing Gum and Postoperative Nausea and Vomiting
General anesthesia for surgery can often lead to postoperative nausea and vomiting (PONV). Additionally, decreased or paralyzed bowel movements are among the most common complications following abdominal surgery, causing pain…
- Trial name
- NCT06446583
- Testing
- Chewing sugar-free gum
- Volunteers
- 92 people
- Sponsor
- Min Suk Chae
Temporomandibular Disorder, Bruxism
Botulinum Toxin Administration on Masticatory Performance
This study aimed to evaluate the effect of botulinum toxin type A (BTX-A) injection on masticatory performance and nutritional status in temporomandibular disorder patients with bruxism caused by both intra-articular and…
- Trial name
- NCT05562531
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Marmara University
Healthy Aging, Gender
The Test of Mastication and Swallowing Solids and the Timed Water Swallow Test
This study aimed to gather more information regarding two clinically relevant tests: The Test of Mastication and Swallowing Solids (TOMASS) and the Timed Water Swallow Test (TWST).
- Conditions
- Healthy Aging, Gender, Swallowing Disorder
- Trial name
- NCT05132452
- Testing
- The Test of Mastication and Swallowing Solids (TOMASS) and the Timed Water Swallow Test (TWST)
- Volunteers
- 298 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Cognitive Dysfunction
Chewing Gum and Cognitive Function
This study is to investigate whether the improvement or maintenance of cognitive function is superior to the control group when gum chewing is performed in elderly people with subjective cognitive decline or mild cognitive…
- Trial name
- NCT05873023
- Testing
- Chewing gum
- Where
- 4 sites in South Korea
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Inha University Hospital
Chronic Kidney Disease
A Study to Evaluate Chitosan Chewing Gum in Patients With Chronic Kidney Disease
The purpose of this study is to determine the efficacy of chitosan chewing gum (K2CG) in reducing serum phosphorus in subjects with chronic kidney disease.
- Trial name
- NCT01475760
- Testing
- K2CG chewing gum (20mg chitosan), K2CG chewing gum (60mg chitosan)
- Where
- 4 sites in United States
- Volunteers
- 167 people
- Sponsor
- Denver Nephrologists, P.C.
Cerebral Palsy
Home-Based Action Observation Training for Chewing and Swallowing Function
This study is a two-part randomized controlled trial designed to investigate the effects of home-based Action Observation Training (AOT) combined with Functional Chewing Training (FuCT) in children with Cerebral Palsy (CP) who…
- Trial name
- NCT06268223
- Testing
- Functional Chewing Exercise, Action Observation Training
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Ondokuz Mayıs University
Overweight, Obesity
Use of Chewing Gum to Facilitate Appetite Control and Weight Loss
This purpose of this study was to test the use of chewing gum as an adjunct to lifestyle modification to facilitate appetite control and weight loss in overweight and obese individuals.
- Trial name
- NCT00871676
- Testing
- Lifestyle modification, Lifestyle modification plus gum
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- University of Pennsylvania
Lumbar Spondylosis
Effect of Chewing Gum on Abdominal Distension in Patients After Lumbar Spine Surgery
According to chewing gum can promote the recovery of gastrointestinal function, it is used as an intervention measure for patients after lumbar surgery to evaluate the effect of chewing gum on improving abdominal distension of…
- Trial name
- NCT04970732
- Testing
- Gum chewing
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Peking University Third Hospital
Thirst
Effectiveness of Menthol Chewing Gum in the Management of Thirst
The objective of this study was to compare the effectiveness of menthol chewing gum compared to maintained fasting (usual care) in reducing the intensity of the surgical patient's thirst during the preoperative period.
- Trial name
- NCT03200197
- Testing
- Menthol chewing gum, Usual care (fasting)
- Volunteers
- 102 people
- Sponsor
- Universidade Estadual de Londrina
Mastication Disorder
Chewing Function in Pediatric Neuromuscular Disorders
We aimed to evaluate chewing function (CF) in children with neuromuscular disorders, and investigate reliability of the Karaduman Chewing Performance Scale (KCPS).
- Trial name
- NCT03116620
- Testing
- Chewing evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Hacettepe University