Clinical trials: Marijuana Intoxication
Marijuana Impairment
Neuroscience of Marijuana Impaired Driving
Marijuana is one of the most widely used substances. However, marijuana intoxication is not fully understood in relation to driving.
- Trial name
- MJDriving (NCT02757313)
- Testing
- Low dose THC marijuana, High dose THC marijuana
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Yale University
Cannabis Intoxication, Alcohol Intoxication
The Impact of Oral Cannabis Administration and Co-Administration of Alcohol on Impairment
This study will evaluate the individual and interactive effects of oral cannabis and alcohol on subjective and behavioral measures of impairment.
- Trial name
- NCT04931095
- Testing
- Cannabis, Alcohol
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Marijuana Impairment
Examine the Feasibility of a Standardized Field Test for Marijuana Impairment: Laboratory Evaluations
Marijuana is one of the most widely used substances. This study will characterize the persistence of cannabis' (CNB's) acute effects on cognitive test performance and simulated driving over a several hour time period.
- Trial name
- NCT03191084
- Testing
- Low Dose THC Marijuana, High Dose THC Marijuana
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Yale University
Acute Cannabinoid Intoxication
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CB1 Antagonist ANEB-001 in a THC Challenge Test
The aim of this study is to investigate whether ANEB-001 effectively penetrates the brain and inhibits the psychotropic effects of Δ9-Tetrahydrocannabinol (THC), the main psychoactive constituent of cannabis.
- Trial name
- NCT05282797
- Testing
- ANEB-001
- Where
- Netherlands
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Anebulo Pharmaceuticals
Driving Under the Influence, Marijuana Intoxication
Cannabis Impairment Detection Application (CIDA)
Subjects will participate in a 4-visit study protocol in which they will be asked to complete a set of computerized tasks and a 45-minute simulated drive in a driving simulator.
- Conditions
- Driving Under the Influence, Marijuana Intoxication, Alcohol Intoxication
- Trial name
- CIDA (NCT04230460)
- Testing
- Cannabis (High% THC) (Inhaled), Cannabis (Very High% THC) (Inhaled), Alcohol (oral)
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Advanced Brain Monitoring, Inc.
Marijuana Impairment
Standardized Field Test for Marijuana Impairment II
This research responds to NHTSA's request with a proposal to increase our understanding of smoked cannabis' (CNB's) acute effects on driving-relevant cognition and simulated driving performance, the persistence of these deficits…
- Trial name
- NHTSA-II (NCT05115513)
- Testing
- Medium THC
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Yale University
Schizophrenia, Cannabis Use
Does Cannabidiol Attenuate the Acute Effects of ∆9-tetrahydrocannabinol Intoxication in Individuals Diagnosed With Schizophrenia? A Double-blind, Randomised, Placebo-controlled Experimental Study
This study will recruit schizophrenia patients who use cannabis recreationally. Each participant will attend the laboratory on three occasions: an initial visit to check that they are safe to join the study and two days of…
- Trial name
- INTEGRATE (NCT04605393)
- Testing
- Cannabidiol, Delta-9-THC
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- King's College London
Cannabis Intoxication, Drug Effects
The Efficacy of a Smart Phone-based Test on Measuring Pupillary Light Reflex Alterations Following Cannabis Use Healthy in Adults
The goal of this open label study is to evaluate the efficacy of smart phone-based test (SOBEREYE OPTOVERA) on measuring pupillary light reflex (PLR) alterations following cannabis use healthy in adults.
- Trial name
- NCT06967051
- Testing
- Tetrahydrocannabinol (10 mg), Tetrahydrocannabinol (25 mg), Pupillary Light Reflex (PLR) Test
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sobereye Inc.
Cannabis Intoxication
Effects of Cannabidiol (CBD) on a Fixed Dose of Delta-9-tetrahydrocannabinol (THC)
This study will evaluate the subjective and behavioral effects of cannabis products containing delta-9-tetrahydrocannabinol and cannabidiol
- Trial name
- NCT07870187
- Testing
- 0mg THC + 0mg CBD Brownie, 10mg THC + 0mg CBD Brownie, 10mg THC + 10mg CBD Brownie
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Cannabis Intoxication in Children
Contamination of Young Children Hair During Acute Cannabis Intoxication
Hair analysis in pediatric cannabis intoxication is limited by possible sudoral self-contamination, especially in young children due to hair porosity. However, adult studies show no THC-COOH in sweat, challenging this hypothesis.
- Trial name
- INTERACTION (NCT07524088)
- Testing
- sudoral and hairing sampling
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Toulouse
Cannabis
Pharmacokinetic and Pharmacodynamic Effects of Smoked and Vaporized Cannabis
Few studies have been conducted to assess the pharmacokinetic and pharmacodynamic effects of smoked and vaporized cannabis. Careful analysis of different cannabis administration methods on these parameters is required to…
- Trial name
- NCT03676166
- Testing
- Cannabis
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Cannabis, Cannabis Intoxication
Do Adolescents and Adults Differ in Their Acute Response to Cannabis?
The acute effects of cannabis may differ between adolescents and adults. Furthermore, these effects may be tempered by the presence of cannabidiol.
- Conditions
- Cannabis, Cannabis Intoxication, Cannabis Use, Cannabis Dependence
- Trial name
- CannTeenA (NCT04851392)
- Testing
- Cannabis with delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), Cannabis with THC without CBD
- Where
- United Kingdom
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University College, London
Pain, Abuse, Drug
Age-dependent Effects of Smoked and Oral Delta-9-THC
This study will assess the age-dependent effects of smoked and oral THC on abuse liability, intoxication, analgesia and impairment as a function of age.
- Conditions
- Pain, Abuse, Drug, Intoxication; Cannabinoids
- Trial name
- SAGE (NCT05865470)
- Testing
- Cannabis, Dronabinol
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles