Clinical trials: Mandibular Fractures
Mandible Fracture
Effect of Adipose Tissue Derived Autologous Mesenchymal Stem Cell Concentrate on Bone Quality in Mandibular Fracture Healing.
The goal of study is to evaluate the effectiveness of adipose tissue derived-MSCs concentrate application in mandibular fractures.
- Trial name
- NCT07671183
- Testing
- Adipose tissue derived mesenchymal stem cells concentrate application in addition to the open reduction and internal fixation., Open reduction and internal fixation
- Volunteers
- 20 people
- Sponsor
- Cairo University
Postoperative Pain, Mandible Fracture
Postoperative Pain After Bupivacaine Supplementation in Mandibular Fracture Surgery
Pain following open reduction of mandibular fractures is the most reported complaint during the first 24 post-operative hours. The goal of this clinical trial is to evaluate the impact of inferior alveolar nerve block with…
- Conditions
- Postoperative Pain, Mandible Fracture, Analgesia, Anesthesia, Local
- Trial name
- NCT06243263
- Testing
- Bupivacain
- Where
- 2 sites in Tunisia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Tunis El Manar
Mandibular Fractures
Bone Regeneration With Mesenchymal Stem Cells
Mandible fractures are a common cause of facial injury in adults. The autologous mesenchymal stem cell (AMSC) transplantation, is proposed as an alternative to the conventional graft treatment, improving bone neoformation.The…
- Trial name
- NCT02755922
- Testing
- Application of autologous mesenchymal stem cells
- Volunteers
- 20 people
- Sponsor
- Instituto Mexicano del Seguro Social
Condylar Neck Fractures, Polyetheretherketone
Clinical and Radiographical Assessment of Patients With Sub-condylar Fracture Using Polyetheretherketone (PEEK) Trapezoidal Plates Versus Titanium Trapezoidal Plates
Some of titanium's drawbacks that is commonly used in maxillofacial surgery included scatter artefacts on regular imaging, implant exposure and inflammation, high thermal conductivity, and high elastic modulus.
- Conditions
- Condylar Neck Fractures, Polyetheretherketone, Mandible Fracture
- Trial name
- NCT06940115
- Testing
- titanium trapezoidal plates, PEEK trapezoidal plates
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Cairo University
Mandibular Fractures
A Multicenter RCT to Investigate the Treatment of Double (Bilateral) Mandibular Fractures
Mandibular fractures represent approximately 50% of the total facial fractures and are commonly (more than half) presented in more than one location. A few simple fractures can be treated using a conservative approach.
- Trial name
- DMFx (NCT02341443)
- Testing
- Implants
- Where
- 11 sites in United States, Finland and 7 more
- Volunteers
- 314 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Mandibular Fracture Treatment
Evaluation of Z-shaped Bone Plates in Management of Mandibular Fractures
he goal of this clinical trial is to evaluate Z shaped bone plate in mandibular fracture treatment regarding post operative healing, function restoration and esthetic.
- Trial name
- z-FIX (NCT07184762)
- Testing
- open reduction and internal fixation with bone plate, z-plates., conventional miniplates.
- Where
- Egypt
- Volunteers
- 18 people
- Sponsor
- Suez Canal University
Mandibular Class Iv Fractures
Patient-Specific Guides vs. Classical Workflow in Class IV Mandibular Fracture Fixation
This study aims to overcome the limitations of current, standard approach of mandibular fracture reduction and fixation including improper alignment of segments, malocclusion, nerve affections and related teeth roots injury.
- Trial name
- NCT07153354
- Testing
- patient-specific screw holes locating surgical guide and pre-bent plates, 2 titanium per-bent mini plates
- Volunteers
- 20 people
- Sponsor
- Mohamed abdelsalam Gaber elkhouly
Mandible Fracture
Comparative Study Evaluating Stability of Fracture Segments After Treatment of Mandibular Angle Fracture With 3d Strut Plate With or Without IMMF.
comparative study evaluating stability of fracture segments in mandibular angle fracture with 3d strut plate with or with out post operative IMMF.
- Trial name
- NCT03640039
- Testing
- 3d strut plate.
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Cairo University
Mandible Fracture, Maxillofacial Trauma
3D Printed Models for Mandibular Fracture Repair
The investigators will test the hypothesis that patients randomized to the intervention (3D printing with pre-bent plate) arm have less operative room time and less time for the critical part of the procedure than patients in the…
- Trial name
- NCT05733221
- Testing
- 3D Printed Model
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- University of Cincinnati
Anterior Mandibular Fracture
Comparing Bone Healing in Jaw Fractures Fixed With Herbert Screws Versus 3D Miniplates
the goal of this clinical trial is to compare two methods of fixing fractures in the front part of the jaw (mandible): second-generation Herbert screws and 3-dimensional miniplates.
- Trial name
- herbert screw (NCT07826416)
- Testing
- headless compression screw, 3D mini plates
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Vitamin C Deficiency, Smoking
The Effect of Vitamin C on Wound Healing In Mandibular Fracture Patients
The goal of this study is to perform a randomized clinical trial to assess the effects of vitamin C versus placebo on wound healing in mandibular fracture patients.
- Conditions
- Vitamin C Deficiency, Smoking, Surgery, Surgery--Complications
- Trial name
- NCT03938584
- Testing
- Vitamin C
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Hennepin Healthcare Research Institute
Mandibular Fractures
Approaches for Open Reduction and Internal Fixation of Mandibular Condylar Fracture
The condylar region is the most frequent anatomical site for mandibular fractures . Condylar fractures constitute 25.5% to 35.5% of all mandibular fractures.
- Trial name
- NCT06333197
- Testing
- ORIF through transparotid approach, ORIF through retroparotid approach
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assiut University
Mandibular Fractures
Assessment of Serum Concentration of Interleukin-17 and Osteoprotegerin in Response to Surgical Trauma Induced by Management of Mandibular Fractures Via Intraoral Versus Extraoral Approaches: Prospective Cohort Study
Assessment of Serum Concentration of Interleukin-17 and Osteoprotegerin in Response to Surgical Trauma Induced by Management of Mandibular Fractures via Intraoral Versus Extraoral Approaches: Prospective Cohort Study
- Trial name
- NCT06349135
- Testing
- Open Reduction & Internal Fixation
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Aya Ayman Ahmed
Posterior Mandibular Fractures
T-prf Versus T-prf and Low-level Laser Stimulation on Bone Healing at Posterior Mandibular Fractures
Different types of grafting substances have been used in the recent decade to accelerate bone healing at large bony facial defects.
- Trial name
- NCT06970379
- Testing
- T-PRF, T-PRF and Laser biomodulation
- Where
- Egypt
- Volunteers
- 14 people
- Sponsor
- Alexandria University
Mandibular Fractures
Mandibular Fracture Reduction Using Bone Reduction Forceps
Different methods have been used in reducing mandibular fractures. Bone reduction forceps provides precise reduction and stabilize mandibular fracture segments.
- Trial name
- NCT04443998
- Testing
- Bone reducion forceps
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Hams Hamed Abdelrahman
Mandibular Fractures
Comparison of Operating Room Time Length With the Use of Virtual Surgical Planning Versus Conventional Treatment of Mandible Fractures
The purpose of this trial is to compare operating room time between conventional treatment techniques [without Virtual surgical Planning (VSP)] versus treatment with use of Virtual surgical Planning (VSP) in patients that undergo…
- Trial name
- NCT04283981
- Testing
- Control group without use of VSP, Treatment Group with use of VSP
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- The University of Texas Health Science Center, Houston
Fracture Mandible
A Comparison of Stryker Hybrid Arch Bars
Patients who sustain a fracture of the lower jaw are typically treated by wiring the teeth together or using small titanium plates and screws to fix the fracture.
- Trial name
- Hybrid (NCT02283528)
- Testing
- Stryker Hybrid, Erich
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Emory University
Mandible Fracture, Rigid Internal Fixation
Comparison of Biodegradable and Titanium Fixation Systems in Mandibular Symphysis or Parasymphysis Solitary Fractures
The mandible bears a wide range of mechanical load from the contraction of masticatory muscles, and has a significant function in normal chewing movements.
- Conditions
- Mandible Fracture, Rigid Internal Fixation, Three-dimensional Finite Element
- Trial name
- NCT02181868
- Testing
- Biodegradable and titanium fixation used in mandibular fractures.
- Where
- China
- Sponsor
- Louqiang Zhang
Mandibular Parasymphyseal Fractures
3D Titanium Plates for Mandibular Parasymphyseal Fracture Fixation
Mandibular fractures pose significant challenges in maxillofacial surgery due to their frequency, potential for functional impairment, and aesthetic concerns.
- Trial name
- NCT07651033
- Testing
- 3D Titanium Plates
- Where
- Egypt
- Volunteers
- 18 people
- Sponsor
- Cairo University
Jaw Fractures, Jaw; Fracture, Upper Jaw
Minimally Invasive Dental Occlusion Ties
Patients sustaining fractures of the upper (maxilla) and/or lower (mandible) jaw may be candidates for the minimally invasive technology evaluated in this study.
- Conditions
- Jaw Fractures, Jaw; Fracture, Upper Jaw, Mandibular Fractures, Maxilla Fracture
- Trial name
- NCT04985461
- Testing
- dental occlusion ties maxillo-mandibular fixation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Altru Health System