Clinical trials: Mammography
Breast Cancer, Screening
Artificial Intelligence in Breast Cancer Screening Programs
The use of artificial intelligence software in breast screening (Transpara®) makes it possible to identify studies with a very low probability of cancer.
- Trial name
- AITIC (NCT04949776)
- Testing
- Mammograms
- Where
- Spain
- Volunteers
- 31,301 people, healthy volunteers welcome
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
Healthy Volunteers
1380GCC: Prospective Study of GP-88 Blood Test in Healthy Women With Baseline Gail Model Risk Assessment Undergoing Screening for Breast Cancer
The purpose of this study is find out if a protein level in the blood (called PC Cell Derived Growth Factor or glycoprotein 88 [GP88]), combined with standard mammography screening, can help detect breast cancer better than…
- Trial name
- 1380GCC (NCT02700776)
- Testing
- Phlebotomy - Blood sampling for GP88 at MM, SOC Tissue biopsy
- Where
- 2 sites in United States
- Volunteers
- 417 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Breast Cancer
A Mammography FastTrack Program in Increasing the Number of Women Undergoing Breast Cancer Screening
RATIONALE: Screening may help doctors find breast cancer cells early and plan better treatment for breast cancer. The Mammography FastTrack program may be effective in increasing the number of patients who undergo mammography.
- Trial name
- NCT00462891
- Testing
- IT System
- Where
- United States
- Volunteers
- 6,730 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Digital Breast Tomosynthesis
The Added Value of DBT Over Mammography in Local Tumor Staging in Patients With BIRADS 4 or 5 Lesions
Compare the diagnostic accuracy of tomosynthesis with 2D mammography in cases with suspected BI-RADS 4 or 5 to determine its potential benefit for staging
- Trial name
- NCT06854887
- Testing
- digital breast tomosynthesis and mammography
- Volunteers
- 64 people
- Sponsor
- Assiut University
Breast Cancer
Assessing Breast Density's Value in Imaging - A Comparative Effectiveness Study
This Breast Cancer Surveillance Consortium (BCSC) ADVANCE study is a large, observational pragmatic comparative effectiveness research study using high-quality, prospectively collected data from BCSC registries to generate…
- Trial name
- BCSC-ADVANCE (NCT02980848)
- Testing
- Screening digital mammography, Screening digital breast tomosynthesis, Screening breast magnetic resonance imaging
- Where
- 7 sites in United States
- Volunteers
- 1,341,172 people
- Sponsor
- University of California, Davis
Breast Cancer
English Mammography Screening Outcomes by Age, Frequency and Test Threshold
Breast cancer screening involves taking mammograms (x-rays) of women's breasts to search for signs of cancer. This study investigates the impact of test threshold, screening interval (frequency) and age of eligibility on…
- Trial name
- ATHENA-M (NCT05247463)
- Testing
- Increase in upper age of eligibility for breast cancer screening from 64 to 70, Screening round length, Screening test threshold
- Where
- United Kingdom
- Volunteers
- 10,000,000 people
- Sponsor
- University of Warwick
Mammogram Scheduled
Video-assisted Intervention for Increasing Mammography Uptake in Private Primary Care in Singapore
Breast cancer is the leading female cancer in Singapore, but 3 in 5 women are not going for their regular mammography screenings at recommended frequencies despite 15 years of nationwide efforts by Breast Screen Singapore.
- Trial name
- NCT02108314
- Testing
- Video Screening and Counselling
- Where
- Singapore
- Volunteers
- 448 people, healthy volunteers welcome
- Sponsor
- National University Health System, Singapore
Breast Cancer Screening, Colon Cancer Screening
Bundled Cancer Screening and Genetic Services Navigation
The goal of this study is to test bundled familial cancer risk assessment + multicancer (colorectal + breast) vs. single (breast) cancer navigation, using a wait list control for colorectal cancer screening referral and…
- Conditions
- Breast Cancer Screening, Colon Cancer Screening, Genetics Predisposition
- Trial name
- NCT07228000
- Testing
- Breast cancer screening navigation, Multicancer screening navigation, Usual care genetics referral
- Where
- 2 sites in United States
- Volunteers
- 820 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Breast Cancer Risk
Total Xenoestrogen Body Burden in Relation to Mammographic Density, a Marker of Breast Cancer Rlisk
Mammographic density is sensitive to estorgen exposure and constitutes a strong intermediate maker of breast cancer risk. We hypothesize that women with higher serum xenoestrogen levels will have greater mammographic density.
- Trial name
- NCT00839696
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- University of Wisconsin, Madison
Breast Neoplasms
Australian Screening Mammography Decision Aid Trial (ASMDAT)
The purpose of the study is to develop and evaluate a decision aid to assist women aged 70 years and over to make an informed choice about whether to continue screening mammography.
- Trial name
- NCT00247442
- Testing
- Decision aid
- Where
- Australia
- Volunteers
- 670 people, healthy volunteers welcome
- Sponsor
- University of Sydney
Breast Cancer
Intra-operative Digital vs. Standard Mammography
A breast biopsy in the operating room may be needed in up to 15% of patients with an abnormality on mammogram. When an abnormality is present but there is no palpable mass, the abnormality must be localized with a wire before…
- Trial name
- NCT01766102
- Testing
- Intra-operative Mammography, Standard Mammography
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Massachusetts General Hospital
Breast Cancer Screening and Diagnosis
Contrast Enhancement Mammography vs MRI for the Surveillance of Women at High Risk of Breast Cancer: Con-trust Randomized Controlled Trial
Women at high risk of breast cancer (BC) should undergo annual magnetic resonance imaging (MRI) and digital mammography (DM) from at least ages 35 to 60.
- Trial name
- CEM (NCT06629896)
- Testing
- Contrast Enhancement Mammography, magnetic resonance imaging (MRI) and digital mammography (DM)
- Where
- Italy
- Volunteers
- 2,200 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Breast Density
Tomosynthesis in Screening Mammography
Tomosynthesis is a new digital mammographic tool which can be performed at the same time as routine screening mammography. It creates CT-like slices through the breast, minimizing the tissue overlap.
- Trial name
- NCT01086241
- Testing
- 2D Mammogram, Tomosynthesis
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- AHS Cancer Control Alberta
Breast Cancer Screening
MADRE (Mammograms Available Due to Research and Education)
The design builds on past studies by integrating social network analysis (SNA) and implementation science (IS) into a longitudinal randomized clinical trial (RCT).
- Trial name
- MADRE (NCT05841355)
- Testing
- Educate, Empower
- Where
- 2 sites in United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Chicago
Molecular Imaging
Evaluation of the Effect of Fasting and Exercise on Uptake of Tc-99m Sestamibi in Breast Tissue
The primary objective of this study is to determine if exercise, fasting, or eating prior to the molecular breast imaging study will have an effect on the uptake of the tracer in the breast tissue.
- Trial name
- NCT01944215
- Testing
- Meal, Exercise, Sestamibi
- Where
- United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Mammographic Breast Density, Mammography
Contrast-enhanced Spectral Mammography (CESM) Breast Cancer Screening
The purpose of this study is to evaluate how well women may adopt a Contrast-enhanced Spectral Mammography (CESM) as their yearly breast screening test compared to the standard 2-D or 3-D mammogram.
- Trial name
- S-CESM (NCT04904757)
- Testing
- Contrast-enhanced spectral mammography (CESM)
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Breast Cancer
Contrast-enhanced Mammography in Women With a Personal History of Breast Cancer and Dense Breast Tissue: Benefit?
This study aims to assess the effectiveness of Contrast-Enhanced Mammography (CEM)as an alternative to traditional ultrasound for breast cancer screening in women with dense breasts and a personal history of breast cancer.
- Trial name
- CEM (NCT06993246)
- Testing
- Contrast-Enhanced Mammography (CEM)
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Jean Seely
Breast Cancer Screening and Diagnosis
National Mammography Database
The National Mammography Database (NMD) leverages data that radiology practices are already collecting under federal mandate by providing them with comparative information for national and regional benchmarking.
- Trial name
- NCT01900821
- Where
- United States
- Volunteers
- 8,000,000 people, healthy volunteers welcome
- Sponsor
- American College of Radiology
Routine Mammography
Pilot Study: Age Extension of NHS Breast Screening Programme
The purpose of this pilot study is to assess the feasibility and acceptability of randomising the phasing-in of the age extension of the NHS Breast Screening Programme in six volunteer sites in different areas of England.
- Trial name
- NCT00890864
- Testing
- Invitation for breast screening
- Volunteers
- 36,000 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Breast Cancer Screening
Safety and Performance of the Multi-Modal UltraSound Tomography (MUST) Device in Breast Cancer Screening
This is a single-center, pilot study being conducted to evaluate the safety and performance of the investigational device (MUST) in detecting malignant lesions in breast tissue.
- Trial name
- NCT04102722
- Testing
- MUST device
- Where
- United States
- Volunteers
- 1,333 people, healthy volunteers welcome
- Sponsor
- Transonic Imaging, Inc.