Clinical trials: Malocclusion
Malocclusion, Angle Class II
The Effect of Timing on Orthodontic Treatment
The aim of this longitudinal randomized investigation is to determine the long-term effects of early headgear treatment on craniofacial structures and dental arches, compared to treatment started later, during the most active…
- Trial name
- NCT02010346
- Testing
- Early headgear treatment
- Volunteers
- 120 people
- Sponsor
- University of Oulu
Osteogenesis Imperfecta
Dental Malocclusion and Craniofacial Development in OI
Osteogenesis imperfecta (OI) is a rare inherited disorder that causes bones to break easily. Individuals with osteogenesis imperfecta break bones often and may have other problems, including hearing loss and pain and difficulty…
- Trial name
- NCT02934451
- Where
- 3 sites in United States, Canada
- Volunteers
- 75 people
- Sponsor
- Baylor College of Medicine
Malocclusion, Angle Class II, Malocclusion, Angle Class III
Facial Aesthetic Analysis Model Based on Clinical Cohort Phenotype to Explore 45° Facial Profile.
Facial aesthetics has always been a complex and subjective concept. The overall facial harmony, along with lip protrusion, which is often a focus for orthodontists, requires evaluation from multiple perspectives.
- Trial name
- NCT06984666
- Testing
- language
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Linyu Xu
Class II Div 2 Incisal Relationship
Comparison Between 2 Protocols for the Treatment of Class II Division 2 Malocclusion
The aim of this prospective study was to compare between two different treatment modalities of class II division 2; to start treatment in upper arch first until adequate overjet is obtained or to start in the lower arch first…
- Trial name
- NCT03833739
- Testing
- Fixed appliance
- Where
- Jordan
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Surgical Complication, Paresthesia
Trial of Bilateral Sagittal Split Osteotomy Induced Paresthesia Using Ultrasonic vs. Reciprocating Saw Instrumentation
The aim of this prospective study is to analyze the postoperative paresthesias experienced in patients who undergo bilateral sagittal split osteotomies (BSSO) using an ultrasonic saw, versus a reciprocating saw.
- Conditions
- Surgical Complication, Paresthesia, Fracture, Nerve Injury
- Trial name
- NCT05205616
- Testing
- Sonopet ultrasonic saw, Reciprocating saw
- Where
- 2 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Patient Comfort, Malocclusion
Comparison of Patient-Reported Comfort Between Two Clear Aligner Trimming-Line Designs: A Split-Mouth Study
The trimming-line design of clear aligners (supragingival versus juxtagingival) is a routine clinical decision whose influence on patient-reported comfort has not been established; available evidence on aligner comfort derives…
- Conditions
- Patient Comfort, Malocclusion, Oral Health
- Trial name
- COMFORT-ALIGN (NCT07660809)
- Testing
- Supragingival trimming-line design, Juxtagingival festooned trimming-line design
- Where
- Romania
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- George Emil Palade University of Medicine, Pharmacy, Sciences and Technology of Targu Mures
Dental Plaque, Oral Hygiene
Smartphone App Versus Verbal Motivation for Oral Hygiene in Fixed Orthodontic Patients
This study looked at whether a smartphone app can help patients with fixed braces keep their teeth cleaner than usual spoken advice alone.
- Conditions
- Dental Plaque, Oral Hygiene, Gingivitis, Malocclusion
- Trial name
- iTeeth (NCT07835022)
- Testing
- Smartphone application for oral-hygiene motivation (iTeeth Orthodontics), Conventional verbal oral-hygiene motivation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Atlas University
Malocclusion, Quality of Life
The Effect of Malocclusions on Oral Health Related Quality of Life
Malocclusions in adolescents may affect oral health related quality of life. The study aims at; 1. Evaluating two instruments measuring oral health related quality of life; "Child Perceptions Questionnaire 11-14" (CPQ 11-14)…
- Conditions
- Malocclusion, Quality of Life, Orthodontics, Adolescent
- Trial name
- NCT05038865
- Testing
- Malocclusion and Orthodontic Treatment
- Where
- 3 sites in Sweden
- Volunteers
- 675 people, healthy volunteers welcome
- Sponsor
- Malmö University
Malocclusion, Craniofacial Morphology
Research on Deep Learning-Based Intelligent Diagnosis and Treatment
This study aims to develop and evaluate deep learning-based artificial intelligence models for craniomaxillofacial multi-modal imaging analysis and clinical decision support.
- Conditions
- Malocclusion, Craniofacial Morphology, Dentofacial Deformities
- Trial name
- NCT07551622
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Xi'an Jiaotong University
Orthodontics, Malocclusion
The Use of 2D and 3D Imaging Modalities and Its Influence on Diagnosis and Treatment Planning in Orthodontics
Research questions: 1. Will the panoramic images derived from cone beam CT data give better diagnostic ability than conventional panoramic radiographs? 2.
- Conditions
- Orthodontics, Malocclusion, Impacted Tooth, Cephalometry
- Trial name
- NCT01246830
- Testing
- Panoramic radiograph, Cephalometric radiograph, Cone-beam computed tomography (CBCT)
- Where
- 2 sites in Belgium
- Volunteers
- 32 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Orthodontic Appliance
Occlusal Bite Force Changes After Surgical Correction of the Increased Vertical Dimension
The aim of this study was to record the OBF changes after surgical correction of mandibular prognathism in patients with or without increased vertical skeletal dimensions at different time intervals (T0: before surgery; T1: at…
- Trial name
- NCT04376645
- Testing
- Mandibular Setback with maxillary impaction, Mandibular setback only
- Where
- Jordan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Dental Malocclusion
The Accuracy of Computer Software Prediction of Soft Tissue Profile for Patients Undergoing Fixed Orthodontic Treatment
A clinical study to evaluate the accuracy of computer software in predicting soft tissue profile changes in patients undergoing fixed orthodontic treatment
- Trial name
- NCT05978856
- Testing
- Accuracy of computer software in predicting soft tissue profile changes
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Malocclusion, Angle Class II
Study to Compare Two Functional Appliances for Class II Malocclusions
A randomised controlled clinical trial to compare the effectiveness of two functional appliances in the correction of a Class II malocclusion.
- Trial name
- NCT03773783
- Testing
- Button and Bead appliance, Twin Block appliance
- Where
- United Kingdom
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Juvenile Idiopathic Arthritis, Malocclusion, Angle Class II
Mandibular Advancement Clear Aligner Treatment in Juvenile Idiopathic Arthritis Subjects
There is currently no information on how mandibular advancement therapy could influence three-dimensionally the condylar and mandibular morphology in growing patients affected by Juvenile Idiopathic Arthritis (JIA).
- Trial name
- NCT05467579
- Testing
- Device: orthodontic - mandibular advancement clear aligner
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Genova
Mandibular Growth Stimulation
Comparison of Skeletal Effects of Herbst and Invisalign MA in Growing Patients With KLass II Malocclusion
This study aims to determine and compare the precise skeletal dental and soft tissue effect of Mandibular advancement aligners and Herbst Appliance.
- Trial name
- NCT06409923
- Testing
- Stimulation of mandibular growth.
- Where
- 2 sites in Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Université Libre de Bruxelles
Malocclusion, Angle Class I
A Comparison Between GUMMETAL and SS Orthodontic Wires in Space Closure
When there is space present between our teeth orthodontically we have the ability to close them through many methods. Using braces as our treatment modality this study will be investigating how efficient a new orthodontic wire is…
- Trial name
- NCT04591080
- Testing
- GUMMETAL Orthodontic Wire, Stainless Steel (CrNi)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Malocclusion, Angle Class III
Evaluation of Different Anchorage-supported Appliances and Expansion Procedures for Face Mask Treatment
The purpose of this study is to assess and compare the effect of two appliances (Hybrid-Hyrax expander/ Bonded rapid maxillary expander (RME)) supported by different anchorage units and two different expansion procedures (routine…
- Trial name
- NCT06244563
- Testing
- Face mask with Hybrid-Hyrax, Face mask with Bonded RME, Alternative Rapid Maxillary Expansion and Contraction Protocol (Alt-RAMEC)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Gaziantep
Malocclusions
Effects of Vitamin D in Patients Undergoing Fixed Orthodontic Mechanotherapy
The goal of this interventional research is to determine the impact of vitamin D intake on substances in saliva, pain, tooth movement, and the density of the bone around teeth in patients during orthodontic treatment.
- Trial name
- NCT07299552
- Testing
- Vitamin D (Calcitriol)
- Where
- Malaysia
- Volunteers
- 48 people
- Sponsor
- Hospital Universiti Sains Malaysia
Class II Malocclusion
Comparative Effect of Conventional and 3D-printed Twin Block Appliances on Soft Tissue Changes
: To evaluate the effectiveness of functional device treatment using both 3D-printed and conventional Twin Block appliances on soft tissue changes during growth modification in Class II malocclusion.
- Trial name
- Clinic Radiogr (NCT07795138)
- Testing
- Twin Block
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Malocclusion
Micro-osteoperforations and Tooth Movement
The purpose of this study is determine the effect the Microosteoperforation (MOPs) using the miniscrew on the rate tooth movement.
- Trial name
- NCT02473471
- Testing
- Micro-osteoperforation
- Where
- Jordan
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology