Clinical trials: Malnourishment
Malnutrition in Children
Women Supporting Women to Improve Infant and Child Feeding Practices in Pakistan
This project aims to reduce child malnutrition in Pakistan by building on local strengths and practical community solutions. The project focuses on children 7-23 months of age.
- Trial name
- NCT07345754
- Testing
- 28-day Behavioural Change Program
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- University of British Columbia
Inflammatory Bowel Diseases, Ileostomy
Malnutrition Associated With Complications After Ileostomy Reversal
An ileostomy is a surgical opening established by bringing the end or a loop of the ileum to discharge directly outside the body.
- Trial name
- NCT03909542
- Where
- United States
- Volunteers
- 359 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Thiamine Deficiency
Further Development and Assessment of Tools to Measure Risk Factors for and Treatment of Thiamine Deficiency Disorders
Thiamine deficiency, including the most severe form infantile beriberi, is a public health concern across South and Southeast Asia, where monotonous diets rely on thiamine-poor white rice.
- Trial name
- NCT05390086
- Testing
- Standard of care
- Where
- 2 sites in Laos
- Volunteers
- 42 people
- Sponsor
- University of California, Davis
Folate Deficiency, Vitamin B 12 Deficiency
Effectiveness of Fortification With Folic Acid and Vitamin B12 Among Teenage Girls
Folic acid and vitamin B12 play an interdependent role in key cellular processes, namely deoxyribonucleic acid synthesis, cell division, red blood cell formation, and nervous system myelination.
- Conditions
- Folate Deficiency, Vitamin B 12 Deficiency, Anemia, Megaloblastic, Cognitive Development
- Trial name
- NCT06100146
- Testing
- Folic acid and vitamin B12 fortified flour, Unfortified cereal flour
- Where
- 2 sites in Ethiopia
- Volunteers
- 472 people, healthy volunteers welcome
- Sponsor
- University Ghent
Prostate Cancer, Radiotherapy Side Effect
PROstate CAncer Radiotherapy - Bowel Quality of Life (PROCAR-BQ)
This is a prospective pilot study to evaluate the mean increase of bowel symptoms after pelvic radiotherapy (RT) in prostate cancer (PCa) patient using the validated \& newly translated EORTC-QLQ PRT20 module.
- Conditions
- Prostate Cancer, Radiotherapy Side Effect, Bowel Dysfunction, Quality of Life
- Trial name
- PROCAR-BQ (NCT05880446)
- Testing
- Bowel symptoms & QoL assessment
- Where
- Belgium
- Volunteers
- 41 people
- Sponsor
- Jules Bordet Institute
Severe Acute Malnutrition, Moderate Acute Malnutrition
Transfer of Healthy Gut Flora for Restoration of Intestinal Microbiota Via Enema for Patients in the Rehabilitative Phase of Malnutrition
This single-center, randomized, open-label trial will compare the safety of MTT delivered by rectal catheter enema in participants 12-60 months of age with malnutrition (moderate acute malnutrition [MAM] or severe acute…
- Trial name
- THRIVE (NCT03087097)
- Testing
- Fecal Microbiota Transplantation
- Where
- South Africa
- Volunteers
- 5 people
- Sponsor
- Microbiome Health Research Institute
Severe Acute Malnutrition, Kwashiorkor
Dietary Rehabilitation in Severely Acutely Malnourished Children
Severe acute malnutrition (SAM) is a life threatening condition and is defined by 1) a weight-for-height Z-score more than three standard deviations (SD) below the median based on the 2006 World Health Organization (WHO) growth…
- Conditions
- Severe Acute Malnutrition, Kwashiorkor, Nutritional Edema, Marasmus
- Trial name
- NCT05009823
- Testing
- Standard F75, Alternative F75 With CMV, Alternative F75 Without CMV
- Where
- Burkina Faso
- Volunteers
- 1,959 people
- Sponsor
- University Ghent
Shock Hypovolemic, Shock, Septic
Management of Shock in Children With SAM or Severe Underweight and Diarrhea
Diarrhea is one of the leading causes of under-five childhood mortality and accounts for 8% of 5.4 million global under-5 deaths.
- Conditions
- Shock Hypovolemic, Shock, Septic, Blood Transfusion, Adrenaline
- Trial name
- NCT04750070
- Testing
- Blood and Dopamine, Blood and adrenaline
- Where
- Bangladesh
- Volunteers
- 135 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Vitamin Deficiency
Study of Absorption Characteristics of Two Multivitamin Mineral Formulations (Gel vs. Tablet/Capsule)
This clinical study is designed to evaluate difference in the AUC of the absorption of Multivitamin and minerals defined in the protocol
- Trial name
- NCT03146273
- Testing
- Multivitamins
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Galilee CBR
Hypovitaminosis D, Obesity
Hypovitaminosis D and "Metabolic" Inflammatory Status in Patients With Obesity
Since obesity is related to systemic chronic inflammatory status and hypovitaminosis D, the study aimed to assess the incidence of hypovitaminosis D in obese patients and the correlations between vitamin D levels, inflammation…
- Trial name
- ViDO (NCT06115356)
- Testing
- Vitamin D Plasma Level, Bioelectrical Impedance Analysis (BIA) technique, Ferritin
- Where
- Italy
- Volunteers
- 208 people
- Sponsor
- University of Trieste
Nutrition in Cancer Survival and Treatment
Delivery of Nutritional Services in Nicaragua
This study investigates nutritional status, at predefined points in therapy, and the association with outcomes in children and adolescents undergoing treatment for cancer in institutions under Asociación de Hemato-Oncología…
- Trial name
- NCT04031586
- Where
- Nicaragua
- Volunteers
- 50 people
- Sponsor
- Columbia University
Malnutrition in Children, Liver Stiffness
Effect of Malnutrition on Liver and Spleen Stiffness in Children
This prospective observational study aims to evaluate the effect of malnutrition on liver and spleen stiffness in children using shear wave elastography.
- Conditions
- Malnutrition in Children, Liver Stiffness, Spleen Stiffness, Shear Wave Elastography
- Trial name
- SWE (NCT06932445)
- Testing
- Shear Wave Elastography
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Mehmet Akif AĞIR
Iron-deficiency, Vitamin A Deficiency
Sub Regional Micronutrient Survey in Ethiopia
To conduct a sub-regional micronutrient survey (SRMNS) assessing the prevalence of vitamin A, Zn, and Fe status in the country
- Conditions
- Iron-deficiency, Vitamin A Deficiency, Zinc Deficiency
- Trial name
- NCT03353662
- Testing
- Women of Gamo Gofa, Children of Gamo Gofa, Women of West Gojjam
- Where
- 2 sites in Ethiopia, Switzerland
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Sickle Cell Anemia, Severe Acute Malnutrition
Management of Severe Acute Malnutrition in SCD, in Northern Nigeria
Except for children with HIV, all recommendations for treatment of childhood malnutrition are for children < 5 years of age. The overall goal of this randomized controlled nutrition feasibility trial is to identify whether…
- Trial name
- NCT03634488
- Testing
- hydroxyurea (20mg/kg/day), Ready-to-use therapeutic food
- Where
- 3 sites in United States, Nigeria
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Risk of Malnutrition
Plant-based Versus Animal-based Oral Nutritional Supplements
Background information: Many people who are admitted to the hospital are at risk of malnutrition. In some patient groups, this can be as high as 40%.
- Trial name
- PAVOS (NCT07399886)
- Testing
- Fresubin Plant-based drink vanilla©, Fresubin Yodrink raspberry©
- Where
- 2 sites in Netherlands
- Volunteers
- 60 people
- Sponsor
- Radboud University Medical Center
Malnutrition, Heart Disease
Enteral Nutrition After Cardiovascular Surgery
Effect of enteral nutrition in the outcome of patients has the objective to determine the effect of implementing a nutritional support protocol on the outcome of cardiovascular surgery patients, the main justification of the…
- Trial name
- NCT01432769
- Testing
- dietary supplement high in energy and protein
- Where
- Mexico
- Volunteers
- 38 people
- Sponsor
- Instituto Mexicano del Seguro Social
Child Development, Parenting
The Sugira Muryango PLAY Collaborative
The Research Program on Children and Adversity (RPCA) has successfully grown its evidence-based home-visiting program-Sugira Muryango (SM)-in Rwanda, as policies and programs aligned with the Rwandan social protection system have…
- Conditions
- Child Development, Parenting, Parent-Child Relations, Child Malnutrition
- Trial name
- NCT04257383
- Testing
- Sugira Muryango
- Where
- Rwanda
- Volunteers
- 1,333 people, healthy volunteers welcome
- Sponsor
- Boston College
Malnutrition
Quality Improvement Program (QIP) to Reduce 30-Day Readmission in Malnourished Hospitalized Patients
Newly admitted patients will be screened for risk of malnutrition. Patients will receive either the feeding protocol or current oral nutrition supplement (ONS) practice, pending location.
- Trial name
- NCT02262429
- Testing
- ONS QIP, ONS Standard Feeding
- Where
- 4 sites in United States
- Volunteers
- 2,386 people
- Sponsor
- Abbott Nutrition
Malnutrition
A Trial of Oral Nutritional Supplements on Nutritional Status and Clinical Outcomes
The purpose of this study is to determine whether short-term use of oral nutritional supplements as part of the diet improves nutritional and functional status of post-hospitalization malnourished elderly.
- Trial name
- NCT01190969
- Testing
- Nutritional Supplement (Ensure Plus)
- Sponsor
- Singapore General Hospital
Sarcopenia, Cirrhosis, Liver
LIver FRAilty Management IN Cirrhosis (LIFRAMIN)
The goal of this clinical trial is to compare food for special medical purposes (Aminolife Plus, by Piemme Pharmatech) vs. placebo in improving muscle mass and function in a cohort of cirrhotic patients.
- Conditions
- Sarcopenia, Cirrhosis, Liver, Malnutrition; Protein
- Trial name
- LIFRAMIN (NCT06573229)
- Testing
- Aminolife Plus by Piemme Pharmatech, Italy
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
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